DE60217507D1 - Peptide für die behandlung von tumoren und anderen zuständen, die das entfernen oder zerstören von zellen erfordern - Google Patents
Peptide für die behandlung von tumoren und anderen zuständen, die das entfernen oder zerstören von zellen erfordernInfo
- Publication number
- DE60217507D1 DE60217507D1 DE60217507T DE60217507T DE60217507D1 DE 60217507 D1 DE60217507 D1 DE 60217507D1 DE 60217507 T DE60217507 T DE 60217507T DE 60217507 T DE60217507 T DE 60217507T DE 60217507 D1 DE60217507 D1 DE 60217507D1
- Authority
- DE
- Germany
- Prior art keywords
- peptides
- removal
- cells
- tumors
- destroying
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Surgery (AREA)
- Virology (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30615001P | 2001-07-19 | 2001-07-19 | |
| US30616101P | 2001-07-19 | 2001-07-19 | |
| US306150P | 2001-07-19 | ||
| US306161P | 2001-07-19 | ||
| US33147701P | 2001-11-16 | 2001-11-16 | |
| US331477P | 2001-11-16 | ||
| PCT/CA2002/001105 WO2003008443A2 (en) | 2001-07-19 | 2002-07-19 | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60217507D1 true DE60217507D1 (de) | 2007-02-22 |
| DE60217507T2 DE60217507T2 (de) | 2007-11-15 |
Family
ID=27405149
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60217507T Expired - Lifetime DE60217507T2 (de) | 2001-07-19 | 2002-07-19 | Peptide für die behandlung von tumoren und anderen zuständen, die das entfernen oder zerstören von zellen erfordern |
| DE60218179T Expired - Lifetime DE60218179T2 (de) | 2001-07-19 | 2002-07-19 | Peptide zur behandlung von tumoren und anderen bedingungen, die die entfernung oder zerstörung von zellen erfordern |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60218179T Expired - Lifetime DE60218179T2 (de) | 2001-07-19 | 2002-07-19 | Peptide zur behandlung von tumoren und anderen bedingungen, die die entfernung oder zerstörung von zellen erfordern |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US7192929B2 (de) |
| EP (2) | EP1417228B1 (de) |
| JP (4) | JP4587667B2 (de) |
| KR (2) | KR100966232B1 (de) |
| CN (1) | CN100475843C (de) |
| AT (1) | ATE353914T1 (de) |
| AU (2) | AU2002319050B2 (de) |
| BR (2) | BRPI0211200B8 (de) |
| CA (2) | CA2453967C (de) |
| CY (1) | CY1108009T1 (de) |
| DE (2) | DE60217507T2 (de) |
| DK (1) | DK1417228T3 (de) |
| EA (1) | EA006603B1 (de) |
| ES (2) | ES2281528T3 (de) |
| IL (2) | IL159903A0 (de) |
| MX (1) | MXPA04000561A (de) |
| NO (1) | NO333999B1 (de) |
| NZ (2) | NZ531114A (de) |
| PL (1) | PL207588B1 (de) |
| PT (1) | PT1417228E (de) |
| WO (2) | WO2003008443A2 (de) |
| ZA (1) | ZA200401320B (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050245451A1 (en) * | 2000-04-05 | 2005-11-03 | Pincus Matthew R | Peptides selectively lethal to malignant and transformed mammalian cells |
| DE60222745T2 (de) * | 2001-03-08 | 2008-07-10 | Nymox Pharmaceutical Corp., St. Laurent | Verwendung von neurofilamentproteinen zur behandlung von tumoren |
| US7271240B2 (en) | 2001-03-14 | 2007-09-18 | Agensys, Inc. | 125P5C8: a tissue specific protein highly expressed in various cancers |
| EA006603B1 (ru) * | 2001-07-19 | 2006-02-24 | Наймокс Корпорейшн | Пептиды, эффективные в лечении опухолей и других заболеваний, требующих удаления или разрушения клеток |
| US7317077B2 (en) * | 2001-11-16 | 2008-01-08 | Nymox Pharmaceutical Corporation | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
| AU2002359572A1 (en) * | 2001-12-04 | 2003-06-17 | Millennium Pharmaceuticals, Inc. | 15603, a human ion channel family member |
| EP1644017A2 (de) * | 2003-07-15 | 2006-04-12 | National Research Council Of Canada | Cyclische analoga des humanen parahormons zur behanldung von erkrankungen, die durch hyperproliferative hautzellen charakterisiert sind |
| US20080227125A1 (en) * | 2003-07-15 | 2008-09-18 | Guilaine Argoud-Puy | Secreted Polypeptide Species Reduced in Cardiovascular Disorders |
| CN1965082A (zh) * | 2004-02-06 | 2007-05-16 | 尼莫克斯股份有限公司 | 人源化抗体 |
| US20060173490A1 (en) | 2005-02-01 | 2006-08-03 | Boston Scientific Scimed, Inc. | Filter system and method |
| DK1994152T3 (da) | 2006-02-28 | 2013-03-11 | Nymox Corp | Peptider der er effektive i behandlingen af tumorer og andre tilstande der kræver fjernelse eller destruktion af celler |
| BRPI0708737A2 (pt) * | 2006-03-10 | 2011-06-14 | Nymox Corp | mÉtodo de prevenÇço ou reduÇço do risco ou incidÊncia de cÂncer utilizando-se peptÍdeos baseados na proteÍna na cadeia neural |
| US20080027005A1 (en) * | 2006-07-31 | 2008-01-31 | Paul Averback | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
| JP5572938B2 (ja) * | 2007-10-25 | 2014-08-20 | 東レ株式会社 | 免疫誘導剤 |
| CA2990255C (en) * | 2007-10-25 | 2023-01-10 | Toray Industries, Inc. | Immune response inducer |
| US9539327B2 (en) * | 2007-11-26 | 2017-01-10 | The Research Foundation For The State University Of New York | Small molecule cancer treatments that cause necrosis in cancer cells but do not affect normal cells |
| EP2293809B1 (de) * | 2008-04-24 | 2019-05-15 | Therimunex Pharmaceuticals, Inc. | Peptidyldiacylglyceride |
| KR101851746B1 (ko) | 2010-09-29 | 2018-04-24 | 어젠시스 인코포레이티드 | 191p4d12 단백질에 결합하는 항체 약물 컨쥬게이트(adc) |
| RU2016117275A (ru) | 2013-11-01 | 2017-12-04 | Сфериум Биомед С.Л. | Тельца включения для трансдермальной доставки терапевтических и косметических средств |
| US20160215031A1 (en) * | 2015-01-27 | 2016-07-28 | Nymox Pharnaceutical Corporation | Method of treating disorders requiring destruction or removal of cells |
| US20160361380A1 (en) | 2015-06-12 | 2016-12-15 | Nymox Corporation | Combination compositions for treating disorders requiring removal or destruction of unwanted cellular proliferations |
| US11628202B2 (en) | 2015-07-24 | 2023-04-18 | Nymox Corporation | Methods of reducing the need for surgery in patients suffering from benign prostatic hyperplasia |
| US10183058B2 (en) | 2016-06-17 | 2019-01-22 | Nymox Corporation | Method of preventing or reducing the progression of prostate cancer |
| US10172910B2 (en) * | 2016-07-28 | 2019-01-08 | Nymox Corporation | Method of preventing or reducing the incidence of acute urinary retention |
| US10532081B2 (en) | 2016-09-07 | 2020-01-14 | Nymox Corporation | Method of ameliorating or preventing the worsening or the progression of symptoms of BPH |
| US10335453B2 (en) | 2017-03-01 | 2019-07-02 | Nymox Corporation | Compositions and methods for improving sexual function |
| US10835538B2 (en) | 2018-03-28 | 2020-11-17 | Nymox Corporation | Method of treating benign prostatic hyperlasia with antibiotics |
| US12239720B2 (en) | 2018-04-06 | 2025-03-04 | Oncolyze, Inc. | Compositions for use in lysis of selective cancer cells |
| US20200061150A1 (en) | 2018-08-23 | 2020-02-27 | Nymox Corporation | Method of inducing selective prostate glandular pharmaco-ablation with sparing of nerves and preservation of sexual function |
| AR117652A1 (es) | 2018-12-03 | 2021-08-25 | Agensys Inc | Composiciones farmacéuticas que comprenden conjugados de anticuerpo anti-191p4d12 y fármaco y métodos de usarlas |
| US11278588B2 (en) | 2019-05-13 | 2022-03-22 | Nymox Corporation | Method of treating lower urinary tract symptoms with fexapotide triflutate |
| US20200360466A1 (en) | 2019-05-13 | 2020-11-19 | Nymox Corporation | Method of improving lower urinary tract symptoms |
| US11298400B2 (en) | 2019-05-13 | 2022-04-12 | Nymox Corporation | Method of enhancing the therapeutic efficacy of fexapotide triflutate in treating LUTS |
| US11331374B2 (en) | 2019-07-31 | 2022-05-17 | Nymox Corporation | Focal treatment of prostate cancer |
| US11231421B2 (en) | 2019-07-31 | 2022-01-25 | Nymox Corporation | Methods of treating multifocal cancer |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5948634A (en) * | 1988-12-21 | 1999-09-07 | The General Hospital Coporation | Neural thread protein gene expression and detection of alzheimer's disease |
| JP3309972B2 (ja) | 1988-12-21 | 2002-07-29 | ザ・ジェネラル・ホスピタル・コーポレイション | 神経系疾患または機能障害の検出法 |
| JP4194664B2 (ja) * | 1997-02-26 | 2008-12-10 | ザ ジェネラル ホスピタル コーポレイション | アルツハイマー病の処置または予防のために効果的な薬物をスクリーニングするためのトランスジェニック動物および細胞株 |
| CA2335986A1 (en) * | 1998-06-26 | 2000-01-06 | Simeng Suy | Use of tempo and tempo derivatives for inducing cell death |
| AU2185199A (en) * | 1998-09-30 | 2000-04-17 | Yoko Aida | Apoptosis inducers |
| EP1135494A2 (de) * | 1998-12-11 | 2001-09-26 | Incyte Pharmaceuticals, Inc. | Mit neuronen assoziierte proteine |
| DK1143994T3 (da) * | 1999-01-11 | 2003-10-20 | Leadd Bv | Anvendelse af apoptosis-fremkaldende midler ved fremstilling af et medikament til behandling af (auto)immunitetssygdomme |
| CA2364630A1 (en) | 1999-03-12 | 2000-09-21 | Human Genome Sciences, Inc. | 50 human secreted proteins |
| JP2002543764A (ja) * | 1999-03-19 | 2002-12-24 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 46個のヒト分泌タンパク質 |
| JP2002541833A (ja) | 1999-03-26 | 2002-12-10 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 49個のヒト分泌タンパク質 |
| JP2003535570A (ja) * | 1999-03-26 | 2003-12-02 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 50個のヒト分泌タンパク質 |
| AU3769700A (en) * | 1999-03-26 | 2000-10-16 | Human Genome Sciences, Inc. | 45 human secreted proteins |
| CN1300779A (zh) | 1999-12-22 | 2001-06-27 | 上海博德基因开发有限公司 | 一种新的多肽-人神经元线蛋白17和编码这种多肽的多核苷酸 |
| CN1300783A (zh) | 1999-12-23 | 2001-06-27 | 上海生元基因开发有限公司 | 新的人神经元线蛋白及其编码序列 |
| WO2002000718A2 (en) * | 2000-06-26 | 2002-01-03 | Millennium Pharmaceuticals, Inc. | A human calcium channel protein and uses thereof |
| CN1352145A (zh) * | 2000-11-10 | 2002-06-05 | 上海博德基因开发有限公司 | 一种新的多肽——锌指蛋白14.08和编码这种多肽的多核苷酸 |
| US6783969B1 (en) * | 2001-03-05 | 2004-08-31 | Nuvelo, Inc. | Cathepsin V-like polypeptides |
| DK1390403T3 (da) | 2001-05-25 | 2007-05-14 | Nymox Corp | Peptider afledt af nervetrådsproteiner og medicinsk anvendelse deraf |
| EA006603B1 (ru) * | 2001-07-19 | 2006-02-24 | Наймокс Корпорейшн | Пептиды, эффективные в лечении опухолей и других заболеваний, требующих удаления или разрушения клеток |
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2002
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- 2002-07-19 CN CNB028164903A patent/CN100475843C/zh not_active Expired - Fee Related
- 2002-07-19 WO PCT/CA2002/001105 patent/WO2003008443A2/en not_active Ceased
- 2002-07-19 EP EP02748517A patent/EP1417228B1/de not_active Expired - Lifetime
- 2002-07-19 PL PL368912A patent/PL207588B1/pl unknown
- 2002-07-19 CA CA2453967A patent/CA2453967C/en not_active Expired - Lifetime
- 2002-07-19 AT AT02748517T patent/ATE353914T1/de active
- 2002-07-19 JP JP2003514002A patent/JP4587667B2/ja not_active Expired - Lifetime
- 2002-07-19 KR KR1020047000844A patent/KR100966232B1/ko not_active Expired - Lifetime
- 2002-07-19 ES ES02748516T patent/ES2281528T3/es not_active Expired - Lifetime
- 2002-07-19 IL IL15990302A patent/IL159903A0/xx unknown
- 2002-07-19 US US10/198,069 patent/US7192929B2/en not_active Expired - Fee Related
- 2002-07-19 AU AU2002319050A patent/AU2002319050B2/en not_active Expired
- 2002-07-19 WO PCT/CA2002/001106 patent/WO2003008444A2/en not_active Ceased
- 2002-07-19 MX MXPA04000561A patent/MXPA04000561A/es active IP Right Grant
- 2002-07-19 BR BRPI0211200A patent/BRPI0211200B8/pt not_active IP Right Cessation
- 2002-07-19 KR KR1020047000843A patent/KR101005130B1/ko not_active Expired - Fee Related
- 2002-07-19 DE DE60217507T patent/DE60217507T2/de not_active Expired - Lifetime
- 2002-07-19 NZ NZ531114A patent/NZ531114A/en not_active IP Right Cessation
- 2002-07-19 BR BR0211199-3A patent/BR0211199A/pt not_active IP Right Cessation
- 2002-07-19 PT PT02748517T patent/PT1417228E/pt unknown
- 2002-07-19 JP JP2003514001A patent/JP2005507647A/ja active Pending
- 2002-07-19 NZ NZ531115A patent/NZ531115A/en not_active IP Right Cessation
- 2002-07-19 ES ES02748517T patent/ES2281529T3/es not_active Expired - Lifetime
- 2002-07-19 DE DE60218179T patent/DE60218179T2/de not_active Expired - Lifetime
- 2002-07-19 US US10/198,070 patent/US7241738B2/en not_active Expired - Lifetime
- 2002-07-19 CA CA2453965A patent/CA2453965C/en not_active Expired - Fee Related
- 2002-07-19 EP EP02748516A patent/EP1417227B1/de not_active Expired - Lifetime
- 2002-07-19 DK DK02748517T patent/DK1417228T3/da active
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2004
- 2004-01-15 IL IL159903A patent/IL159903A/en active IP Right Grant
- 2004-01-16 NO NO20040222A patent/NO333999B1/no not_active IP Right Cessation
- 2004-02-18 ZA ZA2004/01320A patent/ZA200401320B/en unknown
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2007
- 2007-04-26 CY CY20071100553T patent/CY1108009T1/el unknown
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2011
- 2011-02-22 JP JP2011035954A patent/JP2011152133A/ja active Pending
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2013
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