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DE602007006601D1 - Verfahren zur reinigung von tacrolimus - Google Patents

Verfahren zur reinigung von tacrolimus

Info

Publication number
DE602007006601D1
DE602007006601D1 DE602007006601T DE602007006601T DE602007006601D1 DE 602007006601 D1 DE602007006601 D1 DE 602007006601D1 DE 602007006601 T DE602007006601 T DE 602007006601T DE 602007006601 T DE602007006601 T DE 602007006601T DE 602007006601 D1 DE602007006601 D1 DE 602007006601D1
Authority
DE
Germany
Prior art keywords
tacrolimus
cleaning
cleaning tacrolimus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007006601T
Other languages
English (en)
Inventor
Ladislav Cvak
Martin Buchta
Alexandr Jegorov
Pavel Blatny
Vilmos Keri
Andrea Csorvasi
Angela Simon
Gyorgyne Mako
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Works PLC
Original Assignee
Teva Pharmaceutical Works PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Works PLC filed Critical Teva Pharmaceutical Works PLC
Priority claimed from PCT/US2007/006642 external-priority patent/WO2007106587A2/en
Publication of DE602007006601D1 publication Critical patent/DE602007006601D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE602007006601T 2006-03-15 2007-03-15 Verfahren zur reinigung von tacrolimus Active DE602007006601D1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US78275306P 2006-03-15 2006-03-15
US84732306P 2006-09-25 2006-09-25
US86035906P 2006-11-20 2006-11-20
US87482306P 2006-12-13 2006-12-13
US87986907P 2007-01-10 2007-01-10
PCT/US2007/006642 WO2007106587A2 (en) 2006-03-15 2007-03-15 Process for purifying tacrolimus

Publications (1)

Publication Number Publication Date
DE602007006601D1 true DE602007006601D1 (de) 2010-07-01

Family

ID=38510109

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007006601T Active DE602007006601D1 (de) 2006-03-15 2007-03-15 Verfahren zur reinigung von tacrolimus

Country Status (5)

Country Link
US (1) US20080000834A1 (de)
JP (1) JP4700022B2 (de)
DE (1) DE602007006601D1 (de)
IL (1) IL191920A0 (de)
TW (1) TW200815458A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1697383T1 (sl) * 2003-12-05 2014-09-30 Biocon Limited Postopek za čiščenje takrolimusa
JP2010022888A (ja) * 2008-07-15 2010-02-04 Toshiba Corp 水質浄化材料およびそれを用いた水質浄化方法
KR100910165B1 (ko) * 2008-09-18 2009-07-30 (주) 제노텍 은 이온 용액 추출을 이용한 불포화 알킬기를 가진 락톤 화합물 정제방법
KR101344012B1 (ko) 2012-04-09 2013-12-23 인하대학교 산학협력단 모사이동층 크로마토그래피를 이용하여 타크로리무스와 아스코마이신의 혼합액으로부터 타크로리무스를 분리하는 방법
KR101587321B1 (ko) 2013-07-24 2016-01-20 주식회사 엘지화학 연성인쇄회로기판의 구조체
RU2694354C1 (ru) * 2018-09-25 2019-07-11 Закрытое акционерное общество "БиоХимМак СТ" Способ сорбционно-хроматографического выделения и очистки такролимуса
CN114428133B (zh) * 2021-12-28 2023-06-09 江苏知原药业股份有限公司 一种用反相色谱法检测他克莫司软膏中杂质xv含量的方法
CN114516884B (zh) * 2022-01-05 2024-03-19 福建省微生物研究所 一种高纯度他克莫司的提纯方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
US5194378A (en) * 1991-01-28 1993-03-16 Merck & Co., Inc. Process for producing fk-506
US5116756A (en) * 1991-01-28 1992-05-26 Merck & Co., Inc. Process for producing FK-506
WO1993018042A1 (en) * 1992-03-02 1993-09-16 Pfizer Inc. Desosamino derivatives of macrolides as immunosuppressants and antifungal agents
JP2564765B2 (ja) * 1992-03-02 1996-12-18 ファイザー・インコーポレーテッド マクロライド系抗生物質のフルオロ糖誘導体
US5264355A (en) * 1992-07-02 1993-11-23 Merck & Co., Inc. Methlating enzyme from streptomyces MA6858
UA41884C2 (uk) * 1993-11-05 2001-10-15 Амерікан Хоум Продактс Корпорейшн Спосіб відокремлення рапаміцину від кислотних, основних та неполярних нейтральних домішок, присутніх в концентраті екстрактів ферментаційного бульйону або маточних розчинів
US5622866A (en) * 1994-06-23 1997-04-22 Merck & Co., Inc. Expression cassettes useful in construction of integrative and replicative expression vectors for Streptomyces
US5616595A (en) * 1995-06-07 1997-04-01 Abbott Laboratories Process for recovering water insoluble compounds from a fermentation broth
AU773517B2 (en) * 1998-10-02 2004-05-27 Kosan Biosciences, Inc. Polyketide synthase enzymes and recombinant DNA constructs therefor
DK1183261T3 (da) * 1999-05-25 2005-01-17 Fujisawa Pharmaceutical Co Fremgangsmåde til separering af analoge organiske forbindelser
TW553946B (en) * 1999-09-08 2003-09-21 Fujisawa Pharmaceutical Co Method for separating lactone-containing high-molecular weight compounds
CA2433840C (en) * 2001-01-04 2010-05-04 Albert Einstein College Of Medicine Of Yeshiva University Inhibitors of adp-ribosyl transferases, cyclases, and hydrolases, and uses thereof

Also Published As

Publication number Publication date
US20080000834A1 (en) 2008-01-03
TW200815458A (en) 2008-04-01
JP2007262065A (ja) 2007-10-11
IL191920A0 (en) 2009-08-03
JP4700022B2 (ja) 2011-06-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition