DE602005003803D1 - Verfahren zur herstellung von pyrrolidinoximen - Google Patents
Verfahren zur herstellung von pyrrolidinoximenInfo
- Publication number
- DE602005003803D1 DE602005003803D1 DE602005003803T DE602005003803T DE602005003803D1 DE 602005003803 D1 DE602005003803 D1 DE 602005003803D1 DE 602005003803 T DE602005003803 T DE 602005003803T DE 602005003803 T DE602005003803 T DE 602005003803T DE 602005003803 D1 DE602005003803 D1 DE 602005003803D1
- Authority
- DE
- Germany
- Prior art keywords
- production
- oximes
- pyrrolidine oximes
- pyrrolidine
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- RWRDLPDLKQPQOW-UHFFFAOYSA-N tetrahydropyrrole Natural products C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title abstract 4
- -1 PYRROLIDINE OXIMES Chemical class 0.000 title abstract 2
- 208000005171 Dysmenorrhea Diseases 0.000 abstract 1
- 206010013935 Dysmenorrhoea Diseases 0.000 abstract 1
- 208000005107 Premature Birth Diseases 0.000 abstract 1
- 208000006399 Premature Obstetric Labor Diseases 0.000 abstract 1
- 206010036590 Premature baby Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Reproductive Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pregnancy & Childbirth (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04100773 | 2004-02-26 | ||
| EP04100773 | 2004-02-26 | ||
| PCT/EP2005/050852 WO2005082848A2 (en) | 2004-02-26 | 2005-02-28 | Method for preparing pyrrolidine oximes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602005003803D1 true DE602005003803D1 (de) | 2008-01-24 |
| DE602005003803T2 DE602005003803T2 (de) | 2008-12-24 |
Family
ID=34896105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005003803T Expired - Fee Related DE602005003803T2 (de) | 2004-02-26 | 2005-02-28 | Verfahren zur herstellung von pyrrolidinoximen |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20070197794A1 (de) |
| EP (1) | EP1725526B1 (de) |
| JP (1) | JP2007524702A (de) |
| KR (1) | KR20060124775A (de) |
| CN (1) | CN1946686A (de) |
| AT (1) | ATE380792T1 (de) |
| AU (1) | AU2005217153A1 (de) |
| BR (1) | BRPI0508059A (de) |
| CA (1) | CA2554767A1 (de) |
| CY (1) | CY1107139T1 (de) |
| DE (1) | DE602005003803T2 (de) |
| DK (1) | DK1725526T3 (de) |
| EA (1) | EA011026B1 (de) |
| ES (1) | ES2296137T3 (de) |
| IL (1) | IL177388A0 (de) |
| NO (1) | NO20064352L (de) |
| PL (1) | PL1725526T3 (de) |
| PT (1) | PT1725526E (de) |
| SI (1) | SI1725526T1 (de) |
| UA (1) | UA86226C2 (de) |
| WO (1) | WO2005082848A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2845850A1 (de) | 2013-09-10 | 2015-03-11 | ObsEva S.A. | Pyrrolidinderivate als Oxytocin/Vasopressin-V1a-Rezeptorantagonisten |
| EP2886107A1 (de) | 2013-12-17 | 2015-06-24 | ObsEva S.A. | Orale Formulierungen von Pyrrolydinderivaten |
| JP2017519015A (ja) | 2014-07-02 | 2017-07-13 | オブセヴァ エス．エー． | Ｏｔ−ｒ活性に関する疾患を治療するための方法に有用な結晶質の（３ｚ，５ｓ）−５−（ヒドロキシメチル）−１−［（２’−メチル−１，１’−ビフェニル−４−イル）カルボニル］ピロリジン−３−オン о−メチルオキシム |
| WO2021165927A1 (en) * | 2020-02-21 | 2021-08-26 | Wockhardt Bio Ag | 2-cyanopyrroldines, -piperidines or -dazepines as hyperglycemic agents |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6329418B1 (en) * | 1998-04-14 | 2001-12-11 | The Procter & Gamble Company | Substituted pyrrolidine hydroxamate metalloprotease inhibitors |
| EE200200555A (et) * | 2000-03-27 | 2004-06-15 | Applied Research Systems Ars Holding N.V. | Farmatseutiliselt aktiivsed pürrolidiini derivaadid |
| AU2002319237B2 (en) * | 2001-06-18 | 2008-01-03 | Merck Serono Sa | Pyrrolidine oxadiazole- and thiadiazole oxime derivatives being oxytocin receptor antagonists |
-
2005
- 2005-02-28 UA UAA200609783A patent/UA86226C2/uk unknown
- 2005-02-28 WO PCT/EP2005/050852 patent/WO2005082848A2/en not_active Ceased
- 2005-02-28 DK DK05708062T patent/DK1725526T3/da active
- 2005-02-28 PT PT05708062T patent/PT1725526E/pt unknown
- 2005-02-28 AT AT05708062T patent/ATE380792T1/de not_active IP Right Cessation
- 2005-02-28 AU AU2005217153A patent/AU2005217153A1/en not_active Abandoned
- 2005-02-28 BR BRPI0508059-2A patent/BRPI0508059A/pt not_active IP Right Cessation
- 2005-02-28 EP EP05708062A patent/EP1725526B1/de not_active Expired - Lifetime
- 2005-02-28 SI SI200530122T patent/SI1725526T1/sl unknown
- 2005-02-28 CN CNA200580012856XA patent/CN1946686A/zh active Pending
- 2005-02-28 ES ES05708062T patent/ES2296137T3/es not_active Expired - Lifetime
- 2005-02-28 PL PL05708062T patent/PL1725526T3/pl unknown
- 2005-02-28 DE DE602005003803T patent/DE602005003803T2/de not_active Expired - Fee Related
- 2005-02-28 EA EA200601456A patent/EA011026B1/ru not_active IP Right Cessation
- 2005-02-28 JP JP2007500229A patent/JP2007524702A/ja active Pending
- 2005-02-28 CA CA002554767A patent/CA2554767A1/en not_active Abandoned
- 2005-02-28 US US10/590,813 patent/US20070197794A1/en not_active Abandoned
- 2005-02-28 KR KR1020067019448A patent/KR20060124775A/ko not_active Withdrawn
-
2006
- 2006-08-09 IL IL177388A patent/IL177388A0/en unknown
- 2006-09-26 NO NO20064352A patent/NO20064352L/no not_active Application Discontinuation
-
2008
- 2008-01-14 CY CY20081100051T patent/CY1107139T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| UA86226C2 (en) | 2009-04-10 |
| NO20064352L (no) | 2006-09-26 |
| ATE380792T1 (de) | 2007-12-15 |
| EP1725526A2 (de) | 2006-11-29 |
| CY1107139T1 (el) | 2012-10-24 |
| WO2005082848A2 (en) | 2005-09-09 |
| DE602005003803T2 (de) | 2008-12-24 |
| IL177388A0 (en) | 2006-12-10 |
| BRPI0508059A (pt) | 2007-07-17 |
| ES2296137T3 (es) | 2008-04-16 |
| SI1725526T1 (sl) | 2008-04-30 |
| JP2007524702A (ja) | 2007-08-30 |
| US20070197794A1 (en) | 2007-08-23 |
| PT1725526E (pt) | 2007-12-27 |
| DK1725526T3 (da) | 2008-03-03 |
| AU2005217153A1 (en) | 2005-09-09 |
| CN1946686A (zh) | 2007-04-11 |
| EA011026B1 (ru) | 2008-12-30 |
| EP1725526B1 (de) | 2007-12-12 |
| WO2005082848A3 (en) | 2005-12-01 |
| CA2554767A1 (en) | 2005-09-09 |
| PL1725526T3 (pl) | 2008-03-31 |
| KR20060124775A (ko) | 2006-12-05 |
| EA200601456A1 (ru) | 2007-02-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |