DE602005004039D1 - Nicht-peptidische bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus - Google Patents

Nicht-peptidische bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus

Info

Publication number: DE602005004039D1
Authority: DE; Germany
Prior art keywords: peptidic; pharmaceutical compositions; bradykinine; antagonists; bradykinine antagonists
Prior art date: 2004-10-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

DE602005004039T

Other languages

English (en)

Other versions

DE602005004039T2 (de

Inventor

Patrizia Felicetti

Christopher Ingo Fincham

Alessandro Giolitti

Carlo Alberto Maggi

Laura Quartara

Cristina Rossi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Istituto Luso Farmaco dItalia SpA

Original Assignee

Istituto Luso Farmaco dItalia SpA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-10-15

Filing date

2005-09-27

Publication date

2008-02-07

2005-09-27 Application filed by Istituto Luso Farmaco dItalia SpA filed Critical Istituto Luso Farmaco dItalia SpA

2008-02-07 Publication of DE602005004039D1 publication Critical patent/DE602005004039D1/de

2009-01-22 Application granted granted Critical

2009-01-22 Publication of DE602005004039T2 publication Critical patent/DE602005004039T2/de

2025-09-28 Anticipated expiration legal-status Critical

Status Active legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Immunology (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Oncology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Gastroenterology & Hepatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Vascular Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Quinoline Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DE602005004039T 2004-10-15 2005-09-27 Nicht-peptidische bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus Active DE602005004039T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IT001963A ITMI20041963A1 (it)	2004-10-15	2004-10-15	"antagonisti non-peptidici della bradichinina e loro composizioni farmaceutiche"
ITMI20041963		2004-10-15
PCT/EP2005/010412 WO2006040004A1 (en)	2004-10-15	2005-09-27	Non-peptide bradykinin antagonists and pharmaceutical compositions therefrom

Publications (2)

Publication Number	Publication Date
DE602005004039D1 true DE602005004039D1 (de)	2008-02-07
DE602005004039T2 DE602005004039T2 (de)	2009-01-22

Family

ID=35810869

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE602005004039T Active DE602005004039T2 (de)	2004-10-15	2005-09-27	Nicht-peptidische bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus

Country Status (29)

Country	Link
US (1)	US7645759B2 (de)
EP (1)	EP1799214B8 (de)
JP (1)	JP4980917B2 (de)
CN (1)	CN101039671B (de)
AR (1)	AR051392A1 (de)
AT (1)	ATE381931T1 (de)
AU (1)	AU2005293881B2 (de)
BR (1)	BRPI0515983A (de)
CA (1)	CA2583920C (de)
CY (1)	CY1107254T1 (de)
DE (1)	DE602005004039T2 (de)
DK (1)	DK1799214T3 (de)
EA (1)	EA010913B1 (de)
ES (1)	ES2299090T3 (de)
GE (1)	GEP20115322B (de)
HR (1)	HRP20080107T3 (de)
IL (1)	IL182494A (de)
IT (1)	ITMI20041963A1 (de)
MA (1)	MA29007B1 (de)
MX (1)	MX2007004297A (de)
NO (1)	NO339805B1 (de)
NZ (1)	NZ554469A (de)
PL (1)	PL1799214T3 (de)
PT (1)	PT1799214E (de)
RS (1)	RS50563B (de)
SI (1)	SI1799214T1 (de)
UA (1)	UA86091C2 (de)
WO (1)	WO2006040004A1 (de)
ZA (1)	ZA200703009B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ITMI20041963A1 (it) *	2004-10-15	2005-01-15	Luso Farmaco Inst	"antagonisti non-peptidici della bradichinina e loro composizioni farmaceutiche"
WO2008046573A1 (de) *	2006-10-16	2008-04-24	Grünenthal GmbH	Substituierte sulfonamid-derivate als bradykinin 1 rezeptor modulatoren
TWI407960B (zh)	2007-03-23	2013-09-11	Jerini Ag	小分子緩激肽ｂ２受體調節劑
ITMI20072225A1 (it) *	2007-11-23	2009-05-24	Luso Farmaco Inst	"composizioni farmaceutiche a base di antagonisti della bradichinina ed acido ialuronico e loro uso"
IT1391236B1 (it) *	2008-07-11	2011-12-01	St Luso Farm D'italia Spa	Composizioni farmaceutiche a base di antagonisti del recettore b2 delle chinine e corticosteroidi e loro uso
WO2015155323A1 (en) *	2014-04-10	2015-10-15	INSERM (Institut National de la Santé et de la Recherche Médicale)	Br2 antagonist for use in the prevention of the hypotensive effect of patient treated with angiotensin-converting enzyme inhibitors (acei)
CN109716137B (zh) *	2016-09-16	2023-07-21	武田药品工业株式会社	用于与接触活化系统相关的疾病的代谢产物生物标记
HRP20220429T1 (hr)	2017-11-24	2022-05-27	Pharvaris Netherlands B.V.	Novi antagonisti receptora bradikinina b2
UY38707A (es) *	2019-05-23	2020-12-31	Pharvaris Gmbh	Nuevos antagonistas cíclicos del receptor b2 de bradiquinina
UY38706A (es) *	2019-05-23	2020-12-31	Pharvaris Gmbh	Antagonistas cíclicos del receptor b2 de bradiquinina
WO2023180577A1 (en)	2022-03-25	2023-09-28	Pharvaris Gmbh	Therapeutic uses of bradykinin b2-receptor antagonists
US20250228781A1 (en)	2022-03-25	2025-07-17	Pharvaris Gmbh	Solid composition comprising solubilised bradykinin b2-receptor antagonists
TW202345810A (zh)	2022-03-25	2023-12-01	瑞士商帕法瑞斯有限責任公司	包含緩激肽ｂ２受體拮抗劑之固態延長釋放組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ITMI20021247A1 (it) *	2002-06-07	2003-12-09	Menarini Ricerche Spa	Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche
ITMI20041963A1 (it) *	2004-10-15	2005-01-15	Luso Farmaco Inst	"antagonisti non-peptidici della bradichinina e loro composizioni farmaceutiche"
EP1741444A1 (de) *	2005-07-05	2007-01-10	Jerini AG	Antagonisten von Kinin zur Behandlung von Blasenfunktionsstoerungen

2004
- 2004-10-15 IT IT001963A patent/ITMI20041963A1/it unknown
2005
- 2005-09-27 PT PT05789989T patent/PT1799214E/pt unknown
- 2005-09-27 EA EA200700584A patent/EA010913B1/ru not_active IP Right Cessation
- 2005-09-27 UA UAA200702710A patent/UA86091C2/ru unknown
- 2005-09-27 DK DK05789989T patent/DK1799214T3/da active
- 2005-09-27 SI SI200530175T patent/SI1799214T1/sl unknown
- 2005-09-27 AU AU2005293881A patent/AU2005293881B2/en not_active Ceased
- 2005-09-27 WO PCT/EP2005/010412 patent/WO2006040004A1/en not_active Ceased
- 2005-09-27 CN CN2005800348339A patent/CN101039671B/zh not_active Expired - Fee Related
- 2005-09-27 RS RSP-2008/0110A patent/RS50563B/sr unknown
- 2005-09-27 HR HR20080107T patent/HRP20080107T3/xx unknown
- 2005-09-27 DE DE602005004039T patent/DE602005004039T2/de active Active
- 2005-09-27 EP EP05789989A patent/EP1799214B8/de not_active Expired - Lifetime
- 2005-09-27 AT AT05789989T patent/ATE381931T1/de active
- 2005-09-27 PL PL05789989T patent/PL1799214T3/pl unknown
- 2005-09-27 ZA ZA200703009A patent/ZA200703009B/xx unknown
- 2005-09-27 MX MX2007004297A patent/MX2007004297A/es active IP Right Grant
- 2005-09-27 JP JP2007536029A patent/JP4980917B2/ja not_active Expired - Fee Related
- 2005-09-27 NZ NZ554469A patent/NZ554469A/en not_active IP Right Cessation
- 2005-09-27 GE GEAP20059985A patent/GEP20115322B/en unknown
- 2005-09-27 BR BRPI0515983-0A patent/BRPI0515983A/pt not_active Application Discontinuation
- 2005-09-27 ES ES05789989T patent/ES2299090T3/es active Active
- 2005-09-27 CA CA2583920A patent/CA2583920C/en not_active Expired - Fee Related
- 2005-10-14 AR ARP050104324A patent/AR051392A1/es not_active Application Discontinuation
2007
- 2007-04-10 US US11/786,041 patent/US7645759B2/en not_active Expired - Fee Related
- 2007-04-11 NO NO20071840A patent/NO339805B1/no not_active IP Right Cessation
- 2007-04-12 IL IL182494A patent/IL182494A/en not_active IP Right Cessation
- 2007-05-04 MA MA29870A patent/MA29007B1/fr unknown
2008
- 2008-03-20 CY CY20081100314T patent/CY1107254T1/el unknown

Also Published As

Publication number	Publication date
DE602005004039T2 (de)	2009-01-22
AU2005293881B2 (en)	2010-02-25
US20070281944A1 (en)	2007-12-06
SI1799214T1 (sl)	2008-06-30
NO339805B1 (no)	2017-02-06
EP1799214B1 (de)	2007-12-26
MA29007B1 (fr)	2007-11-01
WO2006040004A1 (en)	2006-04-20
HK1107263A1 (en)	2008-04-03
CN101039671B (zh)	2010-10-13
JP2008516901A (ja)	2008-05-22
MX2007004297A (es)	2008-03-11
ATE381931T1 (de)	2008-01-15
AR051392A1 (es)	2007-01-10
EA200700584A1 (ru)	2007-10-26
GEP20115322B (en)	2011-11-10
ZA200703009B (en)	2008-08-27
UA86091C2 (ru)	2009-03-25
CN101039671A (zh)	2007-09-19
PL1799214T3 (pl)	2008-05-30
AU2005293881A1 (en)	2006-04-20
DK1799214T3 (da)	2008-05-13
CA2583920A1 (en)	2006-04-20
EP1799214B8 (de)	2008-06-18
JP4980917B2 (ja)	2012-07-18
CA2583920C (en)	2013-02-12
HRP20080107T3 (en)	2008-05-31
RS50563B (sr)	2010-05-07
US7645759B2 (en)	2010-01-12
BRPI0515983A (pt)	2008-08-12
IL182494A0 (en)	2007-09-20
ES2299090T3 (es)	2008-05-16
NO20071840L (no)	2007-04-11
NZ554469A (en)	2010-02-26
CY1107254T1 (el)	2012-11-21
ITMI20041963A1 (it)	2005-01-15
IL182494A (en)	2011-07-31
EA010913B1 (ru)	2008-12-30
EP1799214A1 (de)	2007-06-27
PT1799214E (pt)	2008-03-31

Publication	Publication Date	Title
BRPI0511900A (pt)	2008-01-22	composições farmacêuticas
EP1748765A4 (de)	2009-11-18	Pharmazeutische suspensionszusammensetzung
IL183583A0 (en)	2007-09-20	Quinazoline derivatives and pharmaceutical compositions containing the same
PL1861387T3 (pl)	2014-08-29	Pochodne benzoimidazolu i ich kompozycje farmaceutyczne
IL223545A0 (en)	2013-02-03	Pharmaceutical compositions
DE60307677D1 (de)	2006-09-28	Dispergierbare pharmazeutische zusammensetzungen
IL183986A0 (en)	2007-10-31	Pharmaceutical compounds and compositions
DK2783682T3 (da)	2019-08-12	Farmaceutisk sammensætning omfattende pimobendan
DK1587478T3 (da)	2013-10-21	Farmaceutisk sammensætning
EP1919288A4 (de)	2009-12-16	Famotidin- und ibuprofenhaltige arzneimittel und ihre verabreichung
DE60329755D1 (de)	2009-12-03	Basische nichtpeptid-bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus
IL221395A0 (en)	2012-09-24	Pharmaceutical compositions comprising alpha ketoamide derivatives and uses thereof
EP1890677A4 (de)	2013-01-30	Pharmazeutische zusammensetzungen und ihre verwendung
DE602005004039D1 (de)	2008-02-07	Nicht-peptidische bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus
PT1861387E (pt)	2014-06-11	Derivados de benzimidazol e composições farmacêuticas dos mesmos
DK1808446T3 (da)	2012-05-14	IL-18-receptor-antagonist og farmaceutisk sammensætning indeholdende antagonisten
IL178067A0 (en)	2006-12-31	Pharmaceutical dosage forms and compositions
MA28603B1 (fr)	2007-05-02	Composition pharmaceutique antimycobacterienne
IL157398A0 (en)	2004-02-19	Pharmaceutical compositions comprising ccr5 antagonists
ATE420118T1 (de)	2009-01-15	Biotinylierte hexadecasaccharide, pharmazeutische zusammensetzungen daraus und deren verwendung
ITMI20041447A1 (it)	2004-10-20	Composizione farmaceutica comprendente gabapentina
DK2474528T3 (da)	2014-10-27	Antineoplastiske forbindelser og farmaceutiske kompositioner deraf
IL189827A0 (en)	2008-11-03	Pharmaceutical dosage forms and compositions comprising lecoztan
ITMI20040943A1 (it)	2004-08-11	Composizione farmaceutica cicatrizzante
EP1809298A4 (de)	2008-06-18	Neuroprotektive pharmazeutische spirostenol-zusammensetzungen

Legal Events

Date	Code	Title	Description
2009-01-15	8364	No opposition during term of opposition