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DE602005004026D1 - Einen transkriptionsfaktor kodierendes humanes prädispositionsgen für autismus sowie dessen verwendungen - Google Patents

Einen transkriptionsfaktor kodierendes humanes prädispositionsgen für autismus sowie dessen verwendungen

Info

Publication number
DE602005004026D1
DE602005004026D1 DE602005004026T DE602005004026T DE602005004026D1 DE 602005004026 D1 DE602005004026 D1 DE 602005004026D1 DE 602005004026 T DE602005004026 T DE 602005004026T DE 602005004026 T DE602005004026 T DE 602005004026T DE 602005004026 D1 DE602005004026 D1 DE 602005004026D1
Authority
DE
Germany
Prior art keywords
autism
gene
diagnosis
disorder
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005004026T
Other languages
English (en)
Other versions
DE602005004026T2 (de
Inventor
Anne Philippi
Francis Rousseau
Peter Brooks
Joerg Hager
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IntegraGen SA
Original Assignee
IntegraGen SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IntegraGen SA filed Critical IntegraGen SA
Publication of DE602005004026D1 publication Critical patent/DE602005004026D1/de
Application granted granted Critical
Publication of DE602005004026T2 publication Critical patent/DE602005004026T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE602005004026T 2004-07-01 2005-06-30 Einen transkriptionsfaktor kodierendes humanes prädispositionsgen für autismus sowie dessen verwendungen Expired - Lifetime DE602005004026T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58413004P 2004-07-01 2004-07-01
US584130P 2004-07-01
PCT/IB2005/002319 WO2006003520A2 (en) 2004-07-01 2005-06-30 Human autism predisposition gene encoding a transcription factor and uses thereof

Publications (2)

Publication Number Publication Date
DE602005004026D1 true DE602005004026D1 (de) 2008-02-07
DE602005004026T2 DE602005004026T2 (de) 2008-12-24

Family

ID=35432082

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005004026T Expired - Lifetime DE602005004026T2 (de) 2004-07-01 2005-06-30 Einen transkriptionsfaktor kodierendes humanes prädispositionsgen für autismus sowie dessen verwendungen

Country Status (10)

Country Link
US (1) US20070218068A1 (de)
EP (1) EP1761649B1 (de)
JP (1) JP4949240B2 (de)
AT (1) ATE382101T1 (de)
AU (1) AU2005258838B2 (de)
CA (1) CA2571365A1 (de)
DE (1) DE602005004026T2 (de)
ES (1) ES2299059T3 (de)
IL (1) IL179751A (de)
WO (1) WO2006003520A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011509096A (ja) * 2008-01-09 2011-03-24 イエール ユニバーシティ 特発性自閉症のリスク増加に関連するコンタクション関連タンパク質2(cntnap2)の突然変異
EP2297352A1 (de) * 2008-06-12 2011-03-23 Integragen Verfahren zur autismusvorhersage
EP2358907B1 (de) * 2008-11-12 2015-05-20 University of Utah Research Foundation Mit autismus assoziierte genetische marker
WO2011067296A1 (en) 2009-12-01 2011-06-09 Integragen A combination of eight risk alleles associated with autism
KR101167942B1 (ko) 2010-02-12 2012-07-23 차의과학대학교 산학협력단 Alg12 유전자로부터 유래된 단일염기다형을 포함하는 폴리뉴클레오티드, 이를 포함하는 마이크로어레이 및 진단키트, 및 이를 이용한 자폐 스펙트럼 장애 분석방법
US20130137585A1 (en) 2010-05-04 2013-05-30 Jerome Carayol New combination of eight risk alleles associated with autism
CN106011237B (zh) * 2011-02-24 2019-12-13 香港中文大学 多胎妊娠的分子测试
CN111808943B (zh) * 2020-06-18 2021-07-20 重庆浦洛通基因医学研究院有限公司 一种精神类个体化用药基因检测方法

Also Published As

Publication number Publication date
AU2005258838A1 (en) 2006-01-12
DE602005004026T2 (de) 2008-12-24
ATE382101T1 (de) 2008-01-15
JP2008504837A (ja) 2008-02-21
WO2006003520A2 (en) 2006-01-12
IL179751A0 (en) 2007-05-15
EP1761649B1 (de) 2007-12-26
WO2006003520A3 (en) 2006-03-02
US20070218068A1 (en) 2007-09-20
ES2299059T3 (es) 2008-05-16
JP4949240B2 (ja) 2012-06-06
EP1761649A2 (de) 2007-03-14
AU2005258838B2 (en) 2009-05-14
CA2571365A1 (en) 2006-01-12
IL179751A (en) 2011-01-31

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