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DE602004028004D1 - Vektoren und zellen zur herstellung von aus transgenen pflanzen gewonnenen immunprotektiven zusammensetzungen - Google Patents

Vektoren und zellen zur herstellung von aus transgenen pflanzen gewonnenen immunprotektiven zusammensetzungen

Info

Publication number
DE602004028004D1
DE602004028004D1 DE602004028004T DE602004028004T DE602004028004D1 DE 602004028004 D1 DE602004028004 D1 DE 602004028004D1 DE 602004028004 T DE602004028004 T DE 602004028004T DE 602004028004 T DE602004028004 T DE 602004028004T DE 602004028004 D1 DE602004028004 D1 DE 602004028004D1
Authority
DE
Germany
Prior art keywords
immunoprotektive
vectors
cells
manufacture
transgenic plants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004028004T
Other languages
English (en)
Inventor
Guy A Cardineau
Hugh Stanley Mason
Joyce M Vaneck
Dwayne D Kirk
Amanda Maree Walmsley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corteva Agriscience LLC
Boyce Thompson Institute
Original Assignee
Boyce Thompson Institute for Plant Research Inc
Dow AgroSciences LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boyce Thompson Institute for Plant Research Inc, Dow AgroSciences LLC filed Critical Boyce Thompson Institute for Plant Research Inc
Publication of DE602004028004D1 publication Critical patent/DE602004028004D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE602004028004T 2003-05-05 2004-05-04 Vektoren und zellen zur herstellung von aus transgenen pflanzen gewonnenen immunprotektiven zusammensetzungen Expired - Lifetime DE602004028004D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46799803P 2003-05-05 2003-05-05
PCT/US2004/014182 WO2004098533A2 (en) 2003-05-05 2004-05-04 Vectors and cells for preparing immunoprotective compositions derived from transgenic plants

Publications (1)

Publication Number Publication Date
DE602004028004D1 true DE602004028004D1 (de) 2010-08-19

Family

ID=33435152

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004028004T Expired - Lifetime DE602004028004D1 (de) 2003-05-05 2004-05-04 Vektoren und zellen zur herstellung von aus transgenen pflanzen gewonnenen immunprotektiven zusammensetzungen

Country Status (13)

Country Link
US (3) US7132291B2 (de)
EP (1) EP1620550B1 (de)
KR (1) KR20060035596A (de)
CN (1) CN100393870C (de)
AR (1) AR044246A1 (de)
AT (1) ATE473271T1 (de)
AU (1) AU2004235813B2 (de)
BR (1) BRPI0410340A (de)
CA (1) CA2524293A1 (de)
DE (1) DE602004028004D1 (de)
NZ (1) NZ543348A (de)
WO (1) WO2004098533A2 (de)
ZA (1) ZA200508930B (de)

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CN1326998C (zh) * 2004-11-25 2007-07-18 中国农业科学院哈尔滨兽医研究所 编码h5亚型禽流感病毒血凝素蛋白的基因及其应用
CA2616859C (en) 2005-08-03 2015-04-14 Fraunhofer Usa, Inc. Compositions and methods for production of immunoglobulins
CA2628308A1 (en) * 2005-11-04 2007-05-18 Dow Agrosciences Llc Preparation of vaccine master cell lines using recombinant plant suspension cultures
KR20080106434A (ko) * 2006-02-13 2008-12-05 프라운호퍼 유에스에이, 인코포레이티드 Ｈｐｖ 항원, 백신 조성물 및 관련된 방법
US8124103B2 (en) * 2006-02-13 2012-02-28 Fraunhofer Usa, Inc Influenza antigens, vaccine compositions, and related methods
US8277816B2 (en) * 2006-02-13 2012-10-02 Fraunhofer Usa, Inc. Bacillus anthracis antigens, vaccine compositions, and related methods
CN101578111A (zh) * 2006-04-21 2009-11-11 美国陶氏益农公司 禽流感疫苗和使用方法
KR100766775B1 (ko) * 2006-04-24 2007-11-01 대한민국 장출혈성대장균(ｅｈｅｃ) 감염증 예방용 톡소이드 백신
CN100487119C (zh) * 2006-05-09 2009-05-13 中国农业科学院哈尔滨兽医研究所 表达禽流感病毒H5亚型HA蛋白的重组新城疫LaSota弱毒疫苗株
EP2029167A4 (de) * 2006-06-16 2010-06-16 Dow Agrosciences Llc Neue dna-sequenzen, vektoren und proteine von vogelgrippe-hämogglutinin
US20080241188A1 (en) * 2007-03-30 2008-10-02 Zeon Corporation Turkey herpesvirus vectored recombinant containing avian influenza genes
EP2152301A4 (de) * 2007-04-28 2010-07-28 Fraunhofer Usa Inc Trypanosomaantigene, impfstoffzusammensetzungen und zugehörige verfahren
PT2155880T (pt) * 2007-06-15 2016-11-18 Medicago Inc Modificação da produção de glicoproteína em plantas
KR100964462B1 (ko) * 2007-07-10 2010-06-16 성균관대학교산학협력단 형질전환 식물 유래의 조류독감 바이러스 백신 및 그 제조방법
US8404252B2 (en) 2007-07-11 2013-03-26 Fraunhofer Usa, Inc. Yersinia pestis antigens, vaccine compositions, and related methods
CA2615372A1 (en) * 2007-07-13 2009-01-13 Marc-Andre D'aoust Influenza virus-like particles (vlps) comprising hemagglutinin
AU2009202819B2 (en) * 2007-07-13 2014-08-28 Aramis Biotechnologies Inc. Recombinant influenza virus-like particles (VLPs) produced in transgenic plants expressing hemagglutinin
EP2190472A2 (de) * 2007-08-20 2010-06-02 Fraunhofer USA, Inc. Prophylaktische und therapeutische influenza-vakzine, antigene, zusammensetzungen und verfahren
SG187500A1 (en) * 2008-01-21 2013-02-28 Medicago Inc Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin
JP5809054B2 (ja) 2008-07-08 2015-11-10 メディカゴ インコーポレイテッド 可溶性組換えインフルエンザ抗原
CN102165062B (zh) 2008-07-18 2017-09-08 麦迪卡格公司 新的流感病毒免疫表位
US8734803B2 (en) 2008-09-28 2014-05-27 Ibio Inc. Humanized neuraminidase antibody and methods of use thereof
US9233148B2 (en) * 2009-01-09 2016-01-12 Samuel Bogoch Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza
EP3009145A1 (de) 2009-03-30 2016-04-20 Mount Sinai School of Medicine of New York University Impfstoffe gegen das grippevirus und ihre verwendungen
MX392585B (es) * 2009-06-24 2025-03-19 Medicago Inc Particulas similares al virus de la influenza quimericas que comprenden hemaglutinina.
JP5551780B2 (ja) 2009-09-22 2014-07-16 メディカゴ インコーポレイテッド 植物由来のタンパク質を調製する方法
CA2776144C (en) 2009-09-29 2020-10-27 Fraunhofer Usa, Inc. Influenza hemagglutinin antibodies, compositions, and related methods
CN103068984B (zh) 2009-12-28 2017-12-01 Dsm Ip资产公司 微藻中血凝素‑神经氨酸酶蛋白的生产
KR20120101572A (ko) 2009-12-28 2012-09-13 메리얼 리미티드 재조합 ｎｄｖ 항원 및 이의 용도
BR112012020839A2 (pt) 2010-02-18 2017-11-21 Sinai School Medicine vacinas para uso na profilaxe e tratamento de doença de vírus da influenza
CN102939103A (zh) 2010-03-30 2013-02-20 西奈山医学院 流感病毒疫苗及其应用
BR112013010385A2 (pt) 2010-10-27 2016-08-02 Philip Morris Products Sa métodos para capturar partículas semelhantes a vírus de plantas usando cromatografia expandida
TWI620816B (zh) 2011-03-23 2018-04-11 苜蓿股份有限公司 植物衍生蛋白回收方法
EP4241785B1 (de) 2011-09-20 2026-01-28 Icahn School of Medicine at Mount Sinai Influenzavirus-impfstoffe und verwendungen davon
NZ622731A (en) * 2011-09-30 2016-04-29 Medicago Inc Increasing virus-like particle yield in plants
US11390878B2 (en) 2011-09-30 2022-07-19 Medicago Inc. Increasing protein yield in plants
CA2895508A1 (en) 2012-12-18 2014-06-26 Icahn School Of Medicine At Mount Sinai Influenza virus vaccines and uses thereof
WO2014159960A1 (en) 2013-03-14 2014-10-02 Icahn School Of Medicine At Mount Sinai Antibodies against influenza virus hemagglutinin and uses thereof
US12467058B2 (en) 2013-03-28 2025-11-11 Aramis Biotechnologies Inc. Influenza virus-like particle production in plants
MX376138B (es) 2013-03-28 2025-03-07 Medicago Inc Produccion de particulas similares a virus de influenza en plantas.
TWI714522B (zh) 2014-01-10 2021-01-01 加拿大商苜蓿股份有限公司 Cpmv強化子元件
US10736956B2 (en) 2015-01-23 2020-08-11 Icahn School Of Medicine At Mount Sinai Influenza virus vaccination regimens
EP3471767A4 (de) 2016-06-15 2020-01-15 Icahn School of Medicine at Mount Sinai Influenzavirus-hämagglutinin-proteine und verwendungen davon
WO2018187706A2 (en) 2017-04-07 2018-10-11 Icahn School Of Medicine At Mount Sinai Anti-influenza b virus neuraminidase antibodies and uses thereof
WO2019246363A1 (en) 2018-06-21 2019-12-26 Icahn School Of Medicine At Mount Sinai Mosaic influenza virus hemagglutinin polypeptides and uses thereof
WO2023026194A1 (en) * 2021-08-24 2023-03-02 Futuragene Israel Ltd. Sequences and promoters for use in plant cells and methods of making and using such sequences
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Also Published As

Publication number Publication date
EP1620550A2 (de) 2006-02-01
CA2524293A1 (en) 2004-11-18
US20080076177A1 (en) 2008-03-27
US7132291B2 (en) 2006-11-07
US20090017065A1 (en) 2009-01-15
US7407802B2 (en) 2008-08-05
EP1620550A4 (de) 2006-06-14
AR044246A1 (es) 2005-09-07
CN100393870C (zh) 2008-06-11
WO2004098533A2 (en) 2004-11-18
AU2004235813A1 (en) 2004-11-18
AU2004235813B2 (en) 2010-07-29
ATE473271T1 (de) 2010-07-15
EP1620550B1 (de) 2010-07-07
NZ543348A (en) 2008-08-29
WO2004098533A3 (en) 2005-08-04
CN1788077A (zh) 2006-06-14
US20050048074A1 (en) 2005-03-03
KR20060035596A (ko) 2006-04-26
ZA200508930B (en) 2007-03-28
BRPI0410340A (pt) 2006-05-30

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