DE602004011806D1 - Verwendung tricyclischer verbindungen als inhibitoren des glycintransports - Google Patents

Verwendung tricyclischer verbindungen als inhibitoren des glycintransports

Info

Publication number: DE602004011806D1
Authority: DE; Germany
Prior art keywords: alkoxy; alkyl; nhso; halo; optionally substituted
Prior art date: 2003-10-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE602004011806T

Other languages

English (en)

Other versions

DE602004011806T2 (de

Inventor

Gihad Dargazanli

Genevieve Estenne-Bouhtou

Pascale Magat

Benoit Marabout

Pierre Roger

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sanofi Aventis France

Original Assignee

Sanofi Aventis France

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-10-17

Filing date

2004-10-15

Publication date

2008-03-27

2004-10-15 Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France

2008-03-27 Publication of DE602004011806D1 publication Critical patent/DE602004011806D1/de

2009-02-05 Application granted granted Critical

2009-02-05 Publication of DE602004011806T2 publication Critical patent/DE602004011806T2/de

2024-10-16 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Addiction (AREA)
Psychology (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)

DE602004011806T 2003-10-17 2004-10-15 Verwendung tricyclischer verbindungen als inhibitoren des glycintransports Expired - Lifetime DE602004011806T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR0312165		2003-10-17
FR0312165A FR2861076B1 (fr)	2003-10-17	2003-10-17	Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique
PCT/FR2004/002643 WO2005037783A2 (fr)	2003-10-17	2004-10-15	Composes tricycliques comme inhibiteurs de transport de glycine

Publications (2)

Publication Number	Publication Date
DE602004011806D1 true DE602004011806D1 (de)	2008-03-27
DE602004011806T2 DE602004011806T2 (de)	2009-02-05

Family

ID=34385252

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE602004011806T Expired - Lifetime DE602004011806T2 (de)	2003-10-17	2004-10-15	Verwendung tricyclischer verbindungen als inhibitoren des glycintransports

Country Status (32)

Country	Link
US (3)	US7288656B2 (de)
EP (1)	EP1680421B1 (de)
JP (1)	JP4853918B2 (de)
KR (1)	KR101125305B1 (de)
CN (2)	CN1882587B (de)
AT (1)	ATE386036T1 (de)
AU (1)	AU2004281217B2 (de)
BR (1)	BRPI0415489A (de)
CA (1)	CA2542647C (de)
CR (1)	CR8342A (de)
CY (1)	CY1108925T1 (de)
DE (1)	DE602004011806T2 (de)
DK (1)	DK1680421T3 (de)
EC (1)	ECSP066511A (de)
ES (1)	ES2300837T3 (de)
FR (1)	FR2861076B1 (de)
HR (1)	HRP20080186T3 (de)
IL (1)	IL174940A (de)
MA (1)	MA28099A1 (de)
ME (1)	ME00111B (de)
NO (1)	NO335462B1 (de)
NZ (1)	NZ547163A (de)
OA (1)	OA13317A (de)
PL (1)	PL1680421T3 (de)
PT (1)	PT1680421E (de)
RS (2)	RS20060314A (de)
RU (1)	RU2346945C2 (de)
SG (1)	SG147435A1 (de)
TN (1)	TNSN06110A1 (de)
UA (1)	UA81186C2 (de)
WO (1)	WO2005037783A2 (de)
ZA (1)	ZA200603861B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2842804B1 (fr)	2002-07-29	2004-09-03	Sanofi Synthelabo	Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique
FR2861076B1 (fr) *	2003-10-17	2006-01-06	Sanofi Synthelabo	Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique
FR2861074B1 (fr) *	2003-10-17	2006-04-07	Sanofi Synthelabo	Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique
FR2861071B1 (fr) *	2003-10-17	2006-01-06	Sanofi Synthelabo	Derives de n-[phenyl(alkylpiperidin-2-yl) methyl]benzamide, leur prepartation et leur application en therapeutique
CA2561993A1 (en) *	2004-03-30	2006-04-13	Painceptor Pharma Corporation	Compositions and methods for modulating gated ion channels
FR2906251B1 (fr) *	2006-09-22	2008-11-07	Sanofi Aventis Sa	Derives de pyrrolizine, indolizine et quinolizine, leur preparation et leur application en therapeutique
US11817637B2 (en)	2006-11-18	2023-11-14	Rfmicron, Inc.	Radio frequency identification (RFID) moisture tag(s) and sensors with extended sensing via capillaries
US9582981B2 (en)	2014-10-08	2017-02-28	Rfmicron, Inc.	Radio frequency identification (RFID) moisture tag(s) and sensors with extended sensing via capillaries
WO2009013535A1 (en) *	2007-07-23	2009-01-29	Astrazeneca Ab	2-azabicyclo(2.2.2)octane derivatives as modulators of the glycine transporter i receptor
CA2691450A1 (en)	2007-08-22	2009-02-26	Abbott Gmbh & Co. Kg	4-benzylaminoquinolines, pharmaceutical compositions containing them, and their use in therapy
ES2397764T3 (es)	2008-04-01	2013-03-11	Abbott Gmbh & Co. Kg	Tetrahidroisoquinolinas, composiciones farmacéuticas que las contienen, y su uso en terapia
WO2010065701A1 (en) *	2008-12-04	2010-06-10	Sanofi-Aventis	Novel polymorphic forms of an azabicyclo-trifluoromethyl benzamide derivative
WO2010087762A1 (en) *	2009-01-28	2010-08-05	Astrazeneca Ab	2-aza-bicyclo[2.2.1]heptane compounds and uses thereof
AR075182A1 (es) *	2009-01-28	2011-03-16	Astrazeneca Ab	Compuestos 2-aza-biciclo (2.2.2) octano y sus usos
FR2941954B1 (fr) *	2009-02-10	2011-04-08	Sanofi Aventis	Derives de n-°(6-aza-bicyclo°3.2.1!oct-1-yl)-aryl-methyl! benzamide, leur preparation et leur application en therapeutique
FR2941953B1 (fr) *	2009-02-10	2011-04-08	Sanofi Aventis	Derives de n-°(2-aza-bicyclo°2.1.1!hex-1-yl)-benzamide, leur preparation et leur application en therapeutique
TW201038569A (en)	2009-02-16	2010-11-01	Abbott Gmbh & Co Kg	Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy
AR075442A1 (es)	2009-02-16	2011-03-30	Abbott Gmbh & Co Kg	Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia
FR2943059A1 (fr) *	2009-03-16	2010-09-17	Sanofi Aventis	Derives de n-°6-aza-bicyclo°3.2.1!oct-5-yl)-aryl-methyl!- heterobenzamide,leur preparation et leur application en therapeutique
FR2943056A1 (fr) *	2009-03-16	2010-09-17	Sanofi Aventis	Derives de n-°2-aza-bicyclo°2.1.1!hex-1-yl)-aryl-methyl!- heterobenzamide, leur preparation et leur application en therapeutique
AR075837A1 (es) *	2009-03-16	2011-04-27	Sanofi Aventis	Derivados de n[(2-aza-biciclo[2,1,1]hex-1-il)-aril-metil] heterobenzamida, su preparacion, composiciones farmaceuticas y su uso en el tratamiento de enfermedades neurodegenerativas
FR2944284A1 (fr) *	2009-04-14	2010-10-15	Sanofi Aventis	Derives de n-°7-aza-bicyclo°2.2.1!hept-1-yl)-aryl-methyl! -benzamide, leur preparation et leur application en therapeutique
US8153653B2 (en) *	2010-06-22	2012-04-10	Hoffmann-La Roche Inc.	Amido-tropane derivatives
US8883839B2 (en)	2010-08-13	2014-11-11	Abbott Laboratories	Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8846743B2 (en)	2010-08-13	2014-09-30	Abbott Laboratories	Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8877794B2 (en)	2010-08-13	2014-11-04	Abbott Laboratories	Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9051280B2 (en)	2010-08-13	2015-06-09	AbbVie Deutschland GmbH & Co. KG	Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US9045459B2 (en)	2010-08-13	2015-06-02	AbbVie Deutschland GmbH & Co. KG	Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9309200B2 (en)	2011-05-12	2016-04-12	AbbVie Deutschland GmbH & Co. KG	Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy
MX2014001457A (es)	2011-08-05	2014-08-21	Abbvie Deutschland	Derivados de aminocromano, de aminotiocromano y de amino-1,2,3,4-tetrahidroquinolina composiciones farmaceuticas que los contienen, y su uso en terapia.
US8846741B2 (en)	2011-11-18	2014-09-30	Abbvie Inc.	N-substituted aminobenzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
WO2013081400A2 (ko) *	2011-11-29	2013-06-06	주식회사 비보존	신규한 벤즈아마이드 유도체 및 그 용도
US9365512B2 (en)	2012-02-13	2016-06-14	AbbVie Deutschland GmbH & Co. KG	Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy
US9656955B2 (en)	2013-03-15	2017-05-23	Abbvie Inc.	Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9650334B2 (en)	2013-03-15	2017-05-16	Abbvie Inc.	Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
MX2016004934A (es)	2013-10-17	2016-12-20	Abbvie Deutschland	Derivados de aminotetralina y aminoindano, composiciones farmaceuticas que los contienen, y su uso en terapia.
MX2016004936A (es)	2013-10-17	2016-12-20	Abbvie Deutschland	Derivados de aminocromano, aminotiocromano y amino-1,2,3,4-tetrahi droquinilina, composiciones farmaceuticas que los contienen, y su uso en terapia.
US9550754B2 (en)	2014-09-11	2017-01-24	AbbVie Deutschland GmbH & Co. KG	4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy
JP6906227B2 (ja) *	2017-08-18	2021-07-21	国立大学法人千葉大学	ハロゲン結合ドナー／有機塩基複合型化合物及び酸塩基複合触媒

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US4066662A (en) *	1973-12-14	1978-01-03	Science Union Et Cie., Societe Francaise De Recherche Medicale	N-substituted-2-aminomethyl-3-azabicyclo(3,3,0)octane compounds
CA1223873A (en) *	1982-04-14	1987-07-07	Francis D. King	Pharmaceutically active compounds
EP0272052B1 (de) *	1986-12-16	1992-07-08	A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation)	Angstlösende N-(1-Azabicyclo[2.2.2)oct-3-yl)benzamide und -thiobenzamide
GB8720805D0 (en) *	1987-09-04	1987-10-14	Naylor R J	2-alkoxy-n-(1-azabicyclo(2 2 2)oct-3-yl)benzamides & thiobenzamides
SE9600683D0 (sv) *	1996-02-23	1996-02-23	Astra Ab	Azabicyclic esters of carbamic acids useful in therapy
AU3254499A (en) *	1998-03-06	1999-09-20	Janssen Pharmaceutica N.V.	Glycine transport inhibitors
FR2861076B1 (fr) *	2003-10-17	2006-01-06	Sanofi Synthelabo	Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique

2003
- 2003-10-17 FR FR0312165A patent/FR2861076B1/fr not_active Expired - Lifetime
2004
- 2004-10-15 AT AT04791554T patent/ATE386036T1/de active
- 2004-10-15 KR KR1020067007370A patent/KR101125305B1/ko not_active Expired - Fee Related
- 2004-10-15 AU AU2004281217A patent/AU2004281217B2/en not_active Ceased
- 2004-10-15 DE DE602004011806T patent/DE602004011806T2/de not_active Expired - Lifetime
- 2004-10-15 OA OA1200600127A patent/OA13317A/fr unknown
- 2004-10-15 CN CN2004800335688A patent/CN1882587B/zh not_active Expired - Fee Related
- 2004-10-15 ES ES04791554T patent/ES2300837T3/es not_active Expired - Lifetime
- 2004-10-15 CA CA2542647A patent/CA2542647C/fr not_active Expired - Fee Related
- 2004-10-15 WO PCT/FR2004/002643 patent/WO2005037783A2/fr not_active Ceased
- 2004-10-15 ZA ZA200603861A patent/ZA200603861B/en unknown
- 2004-10-15 ME MEP-2008-122A patent/ME00111B/me unknown
- 2004-10-15 RS YUP-2006/0314A patent/RS20060314A/sr unknown
- 2004-10-15 EP EP04791554A patent/EP1680421B1/de not_active Expired - Lifetime
- 2004-10-15 HR HR20080186T patent/HRP20080186T3/xx unknown
- 2004-10-15 DK DK04791554T patent/DK1680421T3/da active
- 2004-10-15 SG SG200807634-1A patent/SG147435A1/en unknown
- 2004-10-15 UA UAA200605374A patent/UA81186C2/uk unknown
- 2004-10-15 PL PL04791554T patent/PL1680421T3/pl unknown
- 2004-10-15 JP JP2006534800A patent/JP4853918B2/ja not_active Expired - Fee Related
- 2004-10-15 NZ NZ547163A patent/NZ547163A/en not_active IP Right Cessation
- 2004-10-15 BR BRPI0415489-4A patent/BRPI0415489A/pt not_active IP Right Cessation
- 2004-10-15 CN CN2009101638818A patent/CN101684118B/zh not_active Expired - Fee Related
- 2004-10-15 RS RS20060314A patent/RS51587B/sr unknown
- 2004-10-15 PT PT04791554T patent/PT1680421E/pt unknown
- 2004-10-15 RU RU2006116889/04A patent/RU2346945C2/ru not_active IP Right Cessation
2006
- 2006-04-11 IL IL174940A patent/IL174940A/en not_active IP Right Cessation
- 2006-04-14 US US11/404,273 patent/US7288656B2/en not_active Expired - Lifetime
- 2006-04-17 TN TNP2006000110A patent/TNSN06110A1/fr unknown
- 2006-04-17 MA MA28944A patent/MA28099A1/fr unknown
- 2006-04-17 EC EC2006006511A patent/ECSP066511A/es unknown
- 2006-04-18 CR CR8342A patent/CR8342A/es unknown
- 2006-05-05 NO NO20062030A patent/NO335462B1/no not_active IP Right Cessation
2007
- 2007-09-20 US US11/858,436 patent/US7619089B2/en not_active Expired - Lifetime
2008
- 2008-05-12 CY CY20081100494T patent/CY1108925T1/el unknown
2009
- 2009-10-05 US US12/573,470 patent/US8513246B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US8513246B2 (en)	2013-08-20
CN101684118B (zh)	2013-04-10
RS20060314A (sr)	2008-08-07
ME00111B (me)	2010-10-10
WO2005037783A3 (fr)	2005-07-07
US20060264441A1 (en)	2006-11-23
CY1108925T1 (el)	2014-07-02
US7288656B2 (en)	2007-10-30
RU2346945C2 (ru)	2009-02-20
BRPI0415489A (pt)	2006-12-26
US20080070941A1 (en)	2008-03-20
ZA200603861B (en)	2007-12-27
ECSP066511A (es)	2006-10-10
CA2542647A1 (fr)	2005-04-28
NO20062030L (no)	2006-07-07
NZ547163A (en)	2010-01-29
CN101684118A (zh)	2010-03-31
MEP12208A (en)	2010-06-10
IL174940A (en)	2010-11-30
ATE386036T1 (de)	2008-03-15
US20100022548A1 (en)	2010-01-28
KR20060109432A (ko)	2006-10-20
CN1882587A (zh)	2006-12-20
MA28099A1 (fr)	2006-08-01
SG147435A1 (en)	2008-11-28
JP2007508361A (ja)	2007-04-05
PT1680421E (pt)	2008-05-13
KR101125305B1 (ko)	2012-03-27
AU2004281217A1 (en)	2005-04-28
HK1142887A1 (en)	2010-12-17
FR2861076A1 (fr)	2005-04-22
NO335462B1 (no)	2014-12-15
ES2300837T3 (es)	2008-06-16
UA81186C2 (en)	2007-12-10
TNSN06110A1 (fr)	2007-11-15
IL174940A0 (en)	2006-08-20
CN1882587B (zh)	2012-06-27
PL1680421T3 (pl)	2008-07-31
EP1680421A2 (de)	2006-07-19
WO2005037783A2 (fr)	2005-04-28
RU2006116889A (ru)	2007-11-27
OA13317A (fr)	2007-04-13
CA2542647C (fr)	2012-07-10
CR8342A (es)	2006-10-04
RS51587B (sr)	2011-08-31
EP1680421B1 (de)	2008-02-13
JP4853918B2 (ja)	2012-01-11
FR2861076B1 (fr)	2006-01-06
US7619089B2 (en)	2009-11-17
AU2004281217B2 (en)	2010-07-22
DE602004011806T2 (de)	2009-02-05
HK1098465A1 (en)	2007-07-20
HRP20080186T3 (en)	2008-05-31
DK1680421T3 (da)	2008-06-09

Publication	Publication Date	Title
DE602004011806D1 (de)	2008-03-27	Verwendung tricyclischer verbindungen als inhibitoren des glycintransports
SI1682503T1 (sl)	2007-08-31	Derivati N-(fenil(alkilpiperidin-2-il)metil)benzamida, njihova priprava in njihova terapevtska uporaba
PL1680418T3 (pl)	2008-01-31	Pochodne N-[heteroarylo(piperydyn-2-ylo)metylo]benzamidu, ich wytwarzanie i zastosowanie ich w lecznictwie
NO944162D0 (no)	1994-11-01	Substituerte heterosykliske karboksylsyreamider, deres fremstilling og deres anvendelse som legemiddel
ATE368653T1 (de)	2007-08-15	Oxazolylaryloxyessigsäure derivate und ihre verwendung als ppar agonisten
ATE374765T1 (de)	2007-10-15	Substituierte heterocyclische amide
CO6160331A2 (es)	2010-05-20	Compuestos sustituidos de tetrahidropirrolopirazina que tienen afinidad por los canales kcnq2/3k+ y su uso en medicamentos
DK1268445T3 (da)	2005-11-07	4-amino-5-cyano-2-anilinopyrimidinderivater og deres anvendelse som inhibitorer af cellecykluskinaser
IL189183A0 (en)	2008-06-05	Novel indole compounds
IL174934A0 (en)	2006-08-20	Derivatives of n-[phenyl(pyrrolidine-2-yl) methyl] benzamide and n-[(azepan-2-yl) phenylmethyl] benzamide, preparation method thereof and application of same in therapeutics
ATE261941T1 (de)	2004-04-15	Heterocyclische amide als inhibitoren von faktor xa
ATE396189T1 (de)	2008-06-15	Cyanopyrrolhaltige cyclische carbamat- und thiocarbamatbiaryle und verfahren zu deren herstellung
EA200300010A1 (ru)	2003-06-26	Производные 2-аминотиазолина и их применение в качестве ингибиторов no-синтазы
TH93950A (th)	2009-02-27	อนุพันธ์ 1,4-เบนไซโธอีพีน 1,1- ไดออกไซด์ชนิดใหม่ ที่แทนที่โดยเบนซิลแรดิคัล, วิธีสำหรับการเตรียมสารนั้น, เภสัชภัณฑ์ซึ่งประกอบรวมด้วยสารประกอบเหล่านี้และการใช้สารนั้น

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