DE602004008903D1 - Verfahren zur Gewinnung von Paclitaxel aus Taxuspflanzen - Google Patents
Verfahren zur Gewinnung von Paclitaxel aus TaxuspflanzenInfo
- Publication number
- DE602004008903D1 DE602004008903D1 DE602004008903T DE602004008903T DE602004008903D1 DE 602004008903 D1 DE602004008903 D1 DE 602004008903D1 DE 602004008903 T DE602004008903 T DE 602004008903T DE 602004008903 T DE602004008903 T DE 602004008903T DE 602004008903 D1 DE602004008903 D1 DE 602004008903D1
- Authority
- DE
- Germany
- Prior art keywords
- paclitaxel
- plants containing
- obtaining
- taxus plants
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229930012538 Paclitaxel Natural products 0.000 title abstract 11
- 229960001592 paclitaxel Drugs 0.000 title abstract 11
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title abstract 11
- 238000000034 method Methods 0.000 title abstract 3
- 241001116500 Taxus Species 0.000 title 1
- 238000011210 chromatographic step Methods 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04016493A EP1616868B1 (de) | 2004-07-13 | 2004-07-13 | Verfahren zur Gewinnung von Paclitaxel aus Taxuspflanzen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602004008903D1 true DE602004008903D1 (de) | 2007-10-25 |
| DE602004008903T2 DE602004008903T2 (de) | 2008-06-19 |
Family
ID=34925739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004008903T Expired - Lifetime DE602004008903T2 (de) | 2004-07-13 | 2004-07-13 | Verfahren zur Gewinnung von Paclitaxel aus Taxuspflanzen |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1616868B1 (de) |
| JP (1) | JP4890455B2 (de) |
| KR (1) | KR101142565B1 (de) |
| CN (1) | CN100546986C (de) |
| AT (1) | ATE372993T1 (de) |
| AU (1) | AU2005261970B2 (de) |
| CA (1) | CA2573601C (de) |
| CY (1) | CY1107803T1 (de) |
| DE (1) | DE602004008903T2 (de) |
| DK (1) | DK1616868T3 (de) |
| ES (1) | ES2293129T3 (de) |
| IL (1) | IL180643A (de) |
| NO (1) | NO20070192L (de) |
| NZ (1) | NZ552549A (de) |
| PL (1) | PL1616868T3 (de) |
| PT (1) | PT1616868E (de) |
| RU (1) | RU2373198C2 (de) |
| SI (1) | SI1616868T1 (de) |
| WO (1) | WO2006005429A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102250047B (zh) * | 2011-08-26 | 2013-06-05 | 贺金凤 | 一种紫杉醇化合物的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5071474A (en) * | 1990-06-15 | 1991-12-10 | Allied-Signal Inc. | Method for forging rapidly solidified magnesium base metal alloy billet |
| IT1258838B (it) * | 1992-01-31 | 1996-02-29 | Indena Spa | Processo per l'estrazione di tassolo e derivati da cultivar del genere taxus |
| US6136989A (en) * | 1998-12-30 | 2000-10-24 | Phytogen Life Sciences, Incorporated | Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material |
| US5969165A (en) * | 1999-01-07 | 1999-10-19 | 508037 (Nb) Inc. | Isolation and purification of paclitaxel and other related taxanes by industrial preparative low pressure chromatography on a polymeric resin column |
| CA2299149C (fr) * | 1999-06-22 | 2010-09-21 | Chaichem Pharmaceuticals International | Procede d'isolation et de purification du paclitaxel a partir de sources naturelles |
| US6452024B1 (en) * | 2000-02-22 | 2002-09-17 | Chaichem Pharmaceuticals International | Process for extraction and purification of paclitaxel from natural sources |
| US6229027B1 (en) * | 2000-03-10 | 2001-05-08 | Jian Liu | Process for manufacturing paclitaxel and 13-acetyl-9-dihydrobaccatin IV |
| US6333419B1 (en) * | 2000-11-28 | 2001-12-25 | Indena Spa | Chromatographic separation method of paclitaxel and cephalomannin |
-
2004
- 2004-07-13 PT PT04016493T patent/PT1616868E/pt unknown
- 2004-07-13 DK DK04016493T patent/DK1616868T3/da active
- 2004-07-13 DE DE602004008903T patent/DE602004008903T2/de not_active Expired - Lifetime
- 2004-07-13 SI SI200430492T patent/SI1616868T1/sl unknown
- 2004-07-13 AT AT04016493T patent/ATE372993T1/de active
- 2004-07-13 EP EP04016493A patent/EP1616868B1/de not_active Expired - Lifetime
- 2004-07-13 PL PL04016493T patent/PL1616868T3/pl unknown
- 2004-07-13 ES ES04016493T patent/ES2293129T3/es not_active Expired - Lifetime
- 2004-07-21 KR KR1020040056725A patent/KR101142565B1/ko not_active Expired - Lifetime
-
2005
- 2005-06-24 NZ NZ552549A patent/NZ552549A/en unknown
- 2005-06-24 WO PCT/EP2005/006846 patent/WO2006005429A1/en not_active Ceased
- 2005-06-24 CN CNB2005800234145A patent/CN100546986C/zh not_active Expired - Lifetime
- 2005-06-24 RU RU2007101233/04A patent/RU2373198C2/ru active
- 2005-06-24 CA CA2573601A patent/CA2573601C/en not_active Expired - Lifetime
- 2005-06-24 JP JP2007520696A patent/JP4890455B2/ja not_active Expired - Lifetime
- 2005-06-24 AU AU2005261970A patent/AU2005261970B2/en not_active Expired
-
2007
- 2007-01-11 NO NO20070192A patent/NO20070192L/no not_active Application Discontinuation
- 2007-01-11 IL IL180643A patent/IL180643A/en unknown
- 2007-11-15 CY CY20071101479T patent/CY1107803T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE372993T1 (de) | 2007-09-15 |
| CN100546986C (zh) | 2009-10-07 |
| DK1616868T3 (da) | 2008-01-21 |
| KR20060005958A (ko) | 2006-01-18 |
| PT1616868E (pt) | 2007-12-10 |
| RU2007101233A (ru) | 2008-08-20 |
| EP1616868B1 (de) | 2007-09-12 |
| RU2373198C2 (ru) | 2009-11-20 |
| CN1984896A (zh) | 2007-06-20 |
| AU2005261970B2 (en) | 2011-04-21 |
| DE602004008903T2 (de) | 2008-06-19 |
| HK1101822A1 (zh) | 2007-10-26 |
| EP1616868A1 (de) | 2006-01-18 |
| IL180643A (en) | 2010-12-30 |
| JP4890455B2 (ja) | 2012-03-07 |
| PL1616868T3 (pl) | 2008-02-29 |
| SI1616868T1 (sl) | 2008-02-29 |
| ES2293129T3 (es) | 2008-03-16 |
| CY1107803T1 (el) | 2013-06-19 |
| WO2006005429A1 (en) | 2006-01-19 |
| AU2005261970A1 (en) | 2006-01-19 |
| NZ552549A (en) | 2008-12-24 |
| CA2573601A1 (en) | 2006-01-19 |
| JP2008505946A (ja) | 2008-02-28 |
| KR101142565B1 (ko) | 2012-05-03 |
| CA2573601C (en) | 2012-12-18 |
| NO20070192L (no) | 2007-02-13 |
| IL180643A0 (en) | 2007-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC |