DE602004006438D1 - Verfahren zur herstellung von enantiomeren angereicherten aminosäuren - Google Patents
Verfahren zur herstellung von enantiomeren angereicherten aminosäurenInfo
- Publication number
- DE602004006438D1 DE602004006438D1 DE602004006438T DE602004006438T DE602004006438D1 DE 602004006438 D1 DE602004006438 D1 DE 602004006438D1 DE 602004006438 T DE602004006438 T DE 602004006438T DE 602004006438 T DE602004006438 T DE 602004006438T DE 602004006438 D1 DE602004006438 D1 DE 602004006438D1
- Authority
- DE
- Germany
- Prior art keywords
- amino acids
- preparation
- enriched amino
- enantiomer enriched
- enantiomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001413 amino acids Chemical class 0.000 title 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- -1 N-protected amino Chemical class 0.000 abstract 1
- 150000001576 beta-amino acids Chemical class 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/34—Preparation of optical isomers by separation of optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03028341 | 2003-12-10 | ||
| EP03028341 | 2003-12-10 | ||
| PCT/EP2004/013194 WO2005058776A1 (en) | 2003-12-10 | 2004-11-20 | Process for the preparation of enantiomerically enriched amino acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602004006438D1 true DE602004006438D1 (de) | 2007-06-21 |
| DE602004006438T2 DE602004006438T2 (de) | 2008-01-10 |
Family
ID=34684528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004006438T Expired - Lifetime DE602004006438T2 (de) | 2003-12-10 | 2004-11-20 | Verfahren zur herstellung von enantiomeren angereicherten aminosäuren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7728167B2 (de) |
| EP (1) | EP1692084B1 (de) |
| JP (1) | JP4361094B2 (de) |
| AT (1) | ATE361905T1 (de) |
| CA (1) | CA2547733C (de) |
| DE (1) | DE602004006438T2 (de) |
| DK (1) | DK1692084T3 (de) |
| WO (1) | WO2005058776A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5122871B2 (ja) * | 2007-06-01 | 2013-01-16 | 大東化学株式会社 | 光学活性n−ベンジルオキシカルボニルアミノ酸の製造方法およびジアステレオマー塩 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL1004346C2 (nl) * | 1996-10-23 | 1998-04-24 | Dsm Nv | Werkwijze voor het scheiden van een mengsel van enantiomeren in een geschikt oplosmiddel. |
| US6372936B1 (en) * | 1999-06-09 | 2002-04-16 | Eli Lilly And Company | Optical resolution of aminoisobobutyric acid |
| WO2003016245A1 (en) * | 2001-08-17 | 2003-02-27 | Degussa Ag | Chromatographic separation of enantiomers of protected amino acids via smb-method |
| US6869781B2 (en) | 2002-05-08 | 2005-03-22 | Degussa Ag | Process for the enzymatic preparation of enantiomer-enriched β-amino acids |
| DE10220740A1 (de) * | 2002-05-08 | 2003-11-27 | Degussa | Verfahren zur enzymatischen Herstellung enantiomerenangereicherter beta-Aminosäuren |
| DE10220739A1 (de) | 2002-05-08 | 2003-11-27 | Degussa | Verfahren zur enzymatischen Herstellung enantiomerenangereicherter ß-Amionsäuren |
-
2004
- 2004-11-20 DK DK04803202T patent/DK1692084T3/da active
- 2004-11-20 JP JP2006543410A patent/JP4361094B2/ja not_active Expired - Fee Related
- 2004-11-20 CA CA002547733A patent/CA2547733C/en not_active Expired - Fee Related
- 2004-11-20 EP EP04803202A patent/EP1692084B1/de not_active Expired - Lifetime
- 2004-11-20 AT AT04803202T patent/ATE361905T1/de active
- 2004-11-20 WO PCT/EP2004/013194 patent/WO2005058776A1/en not_active Ceased
- 2004-11-20 DE DE602004006438T patent/DE602004006438T2/de not_active Expired - Lifetime
- 2004-12-09 US US11/007,312 patent/US7728167B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2547733A1 (en) | 2005-06-30 |
| ATE361905T1 (de) | 2007-06-15 |
| EP1692084A1 (de) | 2006-08-23 |
| JP2007513899A (ja) | 2007-05-31 |
| DE602004006438T2 (de) | 2008-01-10 |
| EP1692084B1 (de) | 2007-05-09 |
| CA2547733C (en) | 2009-09-08 |
| JP4361094B2 (ja) | 2009-11-11 |
| DK1692084T3 (da) | 2007-09-03 |
| US7728167B2 (en) | 2010-06-01 |
| WO2005058776A1 (en) | 2005-06-30 |
| US20050171359A1 (en) | 2005-08-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: EVONIK DEGUSSA GMBH, 40474 DUESSELDORF, DE |
|
| 8364 | No opposition during term of opposition |