DE60136921D1 - Medizinische Verwendung von IL-174 Agonisten und Antagonisten - Google Patents

Medizinische Verwendung von IL-174 Agonisten und Antagonisten

Info

Publication number: DE60136921D1
Authority: DE; Germany
Prior art keywords: agonists; antagonists; medical use; cytokine; facts
Prior art date: 2000-04-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60136921T

Other languages

English (en)

Inventor

Stephen D Hurst

Sandra M Zurawski

Donna M Rennick

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck Sharp and Dohme LLC

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-04-18

Filing date

2001-04-17

Publication date

2009-01-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22733587&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60136921(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-04-17 Application filed by Schering Corp filed Critical Schering Corp

2009-01-22 Application granted granted Critical

2009-01-22 Publication of DE60136921D1 publication Critical patent/DE60136921D1/de

2021-04-18 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Hematology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pulmonology (AREA)
Tropical Medicine & Parasitology (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Molecular Biology (AREA)
Virology (AREA)
Dermatology (AREA)
Mycology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Genetics & Genomics (AREA)
Obesity (AREA)
Microbiology (AREA)
Zoology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)

DE60136921T 2000-04-18 2001-04-17 Medizinische Verwendung von IL-174 Agonisten und Antagonisten Expired - Lifetime DE60136921D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US19848800P	2000-04-18	2000-04-18
PCT/US2001/012493 WO2001079288A2 (en)	2000-04-18	2001-04-17	Cytokine uses; compositions; methods

Publications (1)

Publication Number	Publication Date
DE60136921D1 true DE60136921D1 (de)	2009-01-22

Family

ID=22733587

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60136921T Expired - Lifetime DE60136921D1 (de)	2000-04-18	2001-04-17	Medizinische Verwendung von IL-174 Agonisten und Antagonisten

Country Status (14)

Country	Link
US (6)	US6676939B2 (de)
EP (3)	EP1274450B1 (de)
JP (2)	JP2004501088A (de)
AT (1)	ATE416782T1 (de)
AU (1)	AU2001251655A1 (de)
CA (1)	CA2406245A1 (de)
CY (1)	CY1108835T1 (de)
DE (1)	DE60136921D1 (de)
DK (1)	DK1274450T3 (de)
ES (1)	ES2317898T3 (de)
MX (1)	MXPA02010275A (de)
PT (1)	PT1274450E (de)
SI (1)	SI1274450T1 (de)
WO (1)	WO2001079288A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1897943B1 (de) *	1999-12-23	2011-12-14	Genentech, Inc.	IL-17-homologe Polypeptide und ihre therapeutische Verwendung
WO2001079288A2 (en) *	2000-04-18	2001-10-25	Schering Corporation	Cytokine uses; compositions; methods
US20030124092A1 (en) *	2001-06-21	2003-07-03	Eugene Medlock	IL-17 like molecules and uses thereoflike molecules and uses thereof
EP1294765B1 (de) *	2000-06-22	2013-11-27	Amgen, Inc.	Verwendung eines Antikörpers mit Spezifizität für ein Interleukin-17-ähnliches Polypeptid.
EP1824886B1 (de)	2004-11-17	2010-12-22	Amgen Inc.	Vollständige humane monoklonale antikörper gegen il-13
WO2009069355A1 (ja) *	2007-11-28	2009-06-04	Riken	Ｉｌ－１７ｒｂ陽性ｎｋｔ細胞を用いたアレルギー性気道炎症及び／又は気道過敏症の治療薬のスクリーニング方法
US20090317400A1 (en)	2008-05-05	2009-12-24	Krzysztof Masternak	Anti-IL 17A/IL-17F Cross-Reactive Antibodies and Methods of Use Thereof
RU2605318C2 (ru)	2009-05-05	2016-12-20	Новиммун С.А.	Анти-il-17f антитела и способы их применения
PH12012501884B1 (en)	2010-03-30	2018-04-13	Janssen Biotech Inc	Humanized il-25 antibodies
US8956859B1 (en)	2010-08-13	2015-02-17	Aviex Technologies Llc	Compositions and methods for determining successful immunization by one or more vaccines

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US676939A (en) *	1899-11-21	1901-06-25	Samuel S Eveland	Antifriction end-thrust device.
NL154598B (nl)	1970-11-10	1977-09-15	Organon Nv	Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en)	1971-05-14	1974-06-18	Syva Corp	Enzyme amplification assay
US3939350A (en)	1974-04-29	1976-02-17	Board Of Trustees Of The Leland Stanford Junior University	Fluorescent immunoassay employing total reflection for activation
US3996345A (en)	1974-08-12	1976-12-07	Syva Company	Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en)	1978-11-24	1981-06-23	Syva Company	Macromolecular environment control in specific receptor assays
US4277437A (en)	1978-04-05	1981-07-07	Syva Company	Kit for carrying out chemically induced fluorescence immunoassay
US4391904A (en)	1979-12-26	1983-07-05	Syva Company	Test strip kits in immunoassays and compositions therein
US4366241A (en)	1980-08-07	1982-12-28	Syva Company	Concentrating zone method in heterogeneous immunoassays
US4816567A (en)	1983-04-08	1989-03-28	Genentech, Inc.	Recombinant immunoglobin preparations
US4732863A (en)	1984-12-31	1988-03-22	University Of New Mexico	PEG-modified antibody with reduced affinity for cell surface Fc receptors
ES2242966T3 (es) *	1995-07-19	2005-11-16	Genetics Institute, Llc	Ctla-8humana y usos de proteinas relacionadas con ctla-8.
US6569645B2 (en) *	1999-05-14	2003-05-27	Genentech, Inc.	IL-17 homologous polypeptides and therapeutic uses thereof
US6635443B1 (en) *	1997-09-17	2003-10-21	Human Genome Sciences, Inc.	Polynucleotides encoding a novel interleukin receptor termed interleukin-17 receptor-like protein
US6562578B1 (en) *	1999-01-11	2003-05-13	Schering Corporation	IL-17-like cytokine binding compounds and antibodies
AU740405B2 (en)	1998-05-15	2001-11-01	Genentech Inc.	IL-17 homologous polypeptides and therapeutic uses thereof
AU4208799A (en)	1998-05-29	1999-12-13	Human Genome Sciences, Inc.	Interleukins-21 and 22
AU6277799A (en) *	1998-10-02	2000-04-26	Eli Lilly And Company	Il-17 homolog nucleic acids, polypeptides, vectors, host cells, methods and usesthereof
EP1141297B1 (de) *	1999-01-11	2009-09-30	Schering Corporation	Interleukin-17 verwandte zytokine aus säugetieren. dafür kodierende polynukleotide. verwendungen
ES2380958T3 (es) *	1999-12-23	2012-05-21	Genentech, Inc.	Polipéptidos homólogos IL-17 y utilizaciones terapéuticas de los mismos
WO2001079288A2 (en) *	2000-04-18	2001-10-25	Schering Corporation	Cytokine uses; compositions; methods
AU2003263751A1 (en) *	2002-08-05	2004-02-23	Eli Lilly And Company	Novel proteins and their uses

2001
- 2001-04-17 WO PCT/US2001/012493 patent/WO2001079288A2/en not_active Ceased
- 2001-04-17 AU AU2001251655A patent/AU2001251655A1/en not_active Abandoned
- 2001-04-17 DE DE60136921T patent/DE60136921D1/de not_active Expired - Lifetime
- 2001-04-17 EP EP01925057A patent/EP1274450B1/de not_active Revoked
- 2001-04-17 JP JP2001576883A patent/JP2004501088A/ja active Pending
- 2001-04-17 EP EP08017308A patent/EP2020239A1/de not_active Withdrawn
- 2001-04-17 DK DK01925057T patent/DK1274450T3/da active
- 2001-04-17 ES ES01925057T patent/ES2317898T3/es not_active Expired - Lifetime
- 2001-04-17 CA CA002406245A patent/CA2406245A1/en not_active Abandoned
- 2001-04-17 US US09/836,385 patent/US6676939B2/en not_active Expired - Fee Related
- 2001-04-17 EP EP10011811A patent/EP2389943A1/de not_active Withdrawn
- 2001-04-17 PT PT01925057T patent/PT1274450E/pt unknown
- 2001-04-17 AT AT01925057T patent/ATE416782T1/de active
- 2001-04-17 SI SI200130904T patent/SI1274450T1/sl unknown
- 2001-04-17 MX MXPA02010275A patent/MXPA02010275A/es active IP Right Grant
2003
- 2003-11-10 US US10/705,183 patent/US7357924B2/en not_active Expired - Fee Related
2007
- 2007-12-17 US US11/957,994 patent/US20090263401A1/en not_active Abandoned
2009
- 2009-03-03 CY CY20091100242T patent/CY1108835T1/el unknown
- 2009-11-06 US US12/614,003 patent/US20100136020A1/en not_active Abandoned
2011
- 2011-04-20 US US13/090,483 patent/US20110223130A1/en not_active Abandoned
- 2011-08-05 JP JP2011172391A patent/JP2011219501A/ja active Pending
2012
- 2012-01-25 US US13/357,962 patent/US20120141411A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CY1108835T1 (el)	2014-07-02
EP2389943A1 (de)	2011-11-30
US7357924B2 (en)	2008-04-15
US6676939B2 (en)	2004-01-13
DK1274450T3 (da)	2009-04-06
JP2004501088A (ja)	2004-01-15
MXPA02010275A (es)	2003-04-25
SI1274450T1 (sl)	2009-04-30
US20090263401A1 (en)	2009-10-22
EP1274450A2 (de)	2003-01-15
WO2001079288A2 (en)	2001-10-25
ATE416782T1 (de)	2008-12-15
WO2001079288A3 (en)	2002-05-10
US20030165460A1 (en)	2003-09-04
PT1274450E (pt)	2009-03-06
US20100136020A1 (en)	2010-06-03
AU2001251655A1 (en)	2001-10-30
US20120141411A1 (en)	2012-06-07
EP2020239A1 (de)	2009-02-04
US20040076608A1 (en)	2004-04-22
EP1274450B1 (de)	2008-12-10
CA2406245A1 (en)	2001-10-25
JP2011219501A (ja)	2011-11-04
ES2317898T3 (es)	2009-05-01
US20110223130A1 (en)	2011-09-15

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