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DE60129008D1 - Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten - Google Patents

Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten

Info

Publication number
DE60129008D1
DE60129008D1 DE60129008T DE60129008T DE60129008D1 DE 60129008 D1 DE60129008 D1 DE 60129008D1 DE 60129008 T DE60129008 T DE 60129008T DE 60129008 T DE60129008 T DE 60129008T DE 60129008 D1 DE60129008 D1 DE 60129008D1
Authority
DE
Germany
Prior art keywords
formation
protein
inhibit
identifying
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60129008T
Other languages
English (en)
Other versions
DE60129008T2 (de
Inventor
Elaine L Jacobson
Myron K Jacobson
Georg Thomas Wondrak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIADYNE CORP
University of Kentucky
Original Assignee
NIADYNE CORP
University of Kentucky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22730907&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60129008(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by NIADYNE CORP, University of Kentucky filed Critical NIADYNE CORP
Publication of DE60129008D1 publication Critical patent/DE60129008D1/de
Application granted granted Critical
Publication of DE60129008T2 publication Critical patent/DE60129008T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875—Nucleoproteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60129008T 2000-04-14 2001-04-16 Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten Expired - Lifetime DE60129008T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19782900P 2000-04-14 2000-04-14
US197829P 2000-04-14
PCT/US2001/012368 WO2001079842A2 (en) 2000-04-14 2001-04-16 Method for identifying regulators of protein-age formation

Publications (2)

Publication Number Publication Date
DE60129008D1 true DE60129008D1 (de) 2007-08-02
DE60129008T2 DE60129008T2 (de) 2007-10-11

Family

ID=22730907

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60129008T Expired - Lifetime DE60129008T2 (de) 2000-04-14 2001-04-16 Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten

Country Status (13)

Country Link
US (1) US6716635B2 (de)
EP (1) EP1272843B1 (de)
JP (1) JP3920641B2 (de)
CN (1) CN1205480C (de)
AT (1) ATE365319T1 (de)
AU (2) AU2001253555B2 (de)
CY (1) CY1106852T1 (de)
DE (1) DE60129008T2 (de)
DK (1) DK1272843T3 (de)
ES (1) ES2286117T3 (de)
MX (1) MXPA02010194A (de)
PT (1) PT1272843E (de)
WO (1) WO2001079842A2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7452664B2 (en) 1999-12-15 2008-11-18 Massachusetts Institute Of Technology Methods for identifying agents which alter histone protein acetylation
US8642284B1 (en) 1999-12-15 2014-02-04 Massachusetts Institute Of Technology Methods for identifying agents that alter NAD-dependent deacetylation activity of a SIR2 protein
MXPA02010182A (es) * 2000-04-14 2004-08-19 Niadyne Corp Metodos de uso de penicilaminas para el tratamiento de condiciones que resultan del dano en el adn.
US6751792B1 (en) * 2000-10-04 2004-06-15 Sun Microsystems, Inc. Using value-expression graphs for data-flow optimizations
US7572575B2 (en) 2000-12-13 2009-08-11 Massachusetts Institute Of Technology SIR2 activity
CA2495663A1 (en) * 2002-08-16 2004-02-26 Wyeth Compositions and methods for treating rage-associated disorders
EP1693671A4 (de) * 2003-10-29 2008-03-19 Eisai R&D Man Co Ltd Verfahren zur diagnose von morbus alzheimer
FR2863620B1 (fr) * 2003-12-16 2007-05-25 Roquette Freres Utilisation d'au moins un cetose de 3 a 5 atomes de carbone comme substitut d'agents reticulants de proteines
SI1720538T1 (sl) * 2004-03-02 2009-04-30 Ersity Of Arizona The Arizona Postopek za induciranje celične smrti z odstranjevalci karbonila
BRPI0514052A (pt) 2004-08-03 2008-05-27 Transtech Pharma Inc proteìnas de fusão rage e métodos de utilização
KR20070057818A (ko) * 2004-08-03 2007-06-07 트랜스테크 파르마, 인크. Ｒａｇｅ 융합 단백질 및 이의 사용 방법
US20070099830A1 (en) 2005-04-21 2007-05-03 Massachusetts Institute Of Technology Sirt4 activities
RU2431804C2 (ru) * 2005-12-23 2011-10-20 ДжиКоудер Системз АБ Шаблон позиционирования
AU2007215503A1 (en) * 2006-02-09 2007-08-23 Transtech Pharma, Inc. Rage fusion proteins and methods of use
CA2651348A1 (en) * 2006-05-05 2007-11-15 Transtech Pharma, Inc. Rage fusion proteins, formulations, and methods of use thereof
US20080199467A1 (en) * 2007-02-15 2008-08-21 Mjalli Adnan M M Immunoglobulin fusion proteins and methods of making
RU2513695C2 (ru) * 2007-06-14 2014-04-20 Гэлэктика Фармасьютикалс, Инк. Слитые белки rage
EP2421892A1 (de) 2009-04-20 2012-02-29 Pfizer Inc. Steuerung der proteinglycosylierung und damit in zusammenhang stehende zusammensetzungen und verfahren
US9309304B2 (en) * 2012-05-16 2016-04-12 Cornell University Glycation cross-link breakers to increase resistance to enzymatic degradation
CN108776131B (zh) * 2018-03-19 2020-06-09 深圳市南山区疾病预防控制中心 一种食品中AGEs含量的检测方法
CN109970730B (zh) * 2019-04-30 2022-06-17 华东理工大学 一种双功能荧光探针及其制备方法和应用
JP7411205B2 (ja) * 2019-09-30 2024-01-11 丸善製薬株式会社 ＡＧＥｓ形成抑制剤及びその製造方法
CN111007135B (zh) * 2019-12-25 2022-08-02 广东食品药品职业学院 一种植物提取物抗糖化效果的评估方法
CN118020929A (zh) * 2023-12-26 2024-05-14 仙乐健康科技股份有限公司 一种抗蛋白质羰基化的组合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2711990B1 (fr) 1993-11-05 1995-12-08 Exsymol Sa Produit pseudodipeptide possédant un groupement imidazole, et applications thérapeutiques, cosmétologiques et agroalimentaires.
FR2776188B1 (fr) 1998-03-20 2000-06-16 Fabre Pierre Dermo Cosmetique Oleamide de glycylglycine en dermo-cosmetologie

Also Published As

Publication number Publication date
MXPA02010194A (es) 2004-08-19
HK1059117A1 (en) 2004-06-18
WO2001079842A2 (en) 2001-10-25
EP1272843A2 (de) 2003-01-08
CN1451096A (zh) 2003-10-22
US20020037496A1 (en) 2002-03-28
US6716635B2 (en) 2004-04-06
CY1106852T1 (el) 2012-05-23
CN1205480C (zh) 2005-06-08
DE60129008T2 (de) 2007-10-11
PT1272843E (pt) 2007-10-01
JP2003531376A (ja) 2003-10-21
AU5355501A (en) 2001-10-30
DK1272843T3 (da) 2007-10-08
WO2001079842A3 (en) 2002-10-24
AU2001253555B2 (en) 2005-01-06
ATE365319T1 (de) 2007-07-15
JP3920641B2 (ja) 2007-05-30
ES2286117T3 (es) 2007-12-01
EP1272843B1 (de) 2007-06-20

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