DE60129751D1 - Mass spectrometer and mass spectrometric method - Google Patents
Mass spectrometer and mass spectrometric methodInfo
- Publication number
- DE60129751D1 DE60129751D1 DE60129751T DE60129751T DE60129751D1 DE 60129751 D1 DE60129751 D1 DE 60129751D1 DE 60129751 T DE60129751 T DE 60129751T DE 60129751 T DE60129751 T DE 60129751T DE 60129751 D1 DE60129751 D1 DE 60129751D1
- Authority
- DE
- Germany
- Prior art keywords
- analyser
- sensitivity mode
- mass
- ions
- dynamic range
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/40—Time-of-flight spectrometers
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/06—Electron- or ion-optical arrangements
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
Abstract
A way of increasing the dynamic range of a mass spectrometer which incorporates a time to digital converter such as commonly used with a time of flight mass analyser 9 is disclosed. A z-lens 4 upstream of the analyser 9 can be switched between a high sensitivity mode wherein a beam of ions 2 passing therethrough is substantially focused on to the entrance slit 10 of the analyser 9, and a low sensitivity mode wherein the beam of ions 2 is defocused so that the diameter of the beam substantially exceeds that of the entrance slit 10 of the analyser 9. Obtaining data in the low sensitivity mode in combination with obtaining data in the high sensitivity mode enable an order of magnitude increase in the dynamic range to be obtained. <IMAGE>
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0029040 | 2000-11-29 | ||
| GBGB0029040.3A GB0029040D0 (en) | 2000-11-29 | 2000-11-29 | Orthogonal time of flight mass spectrometer |
| GB0108187 | 2001-04-02 | ||
| GB0108187A GB2369721B (en) | 2000-11-29 | 2001-04-02 | Mass spectrometer and method of mass spectrometry |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60129751D1 true DE60129751D1 (en) | 2007-09-13 |
| DE60129751T2 DE60129751T2 (en) | 2008-04-30 |
Family
ID=26245351
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60126048T Expired - Lifetime DE60126048T2 (en) | 2000-11-29 | 2001-11-29 | Mass spectrometer and mass spectrometric method |
| DE60129751T Expired - Lifetime DE60129751T2 (en) | 2000-11-29 | 2001-11-29 | Mass spectrometer and mass spectrometric method |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60126048T Expired - Lifetime DE60126048T2 (en) | 2000-11-29 | 2001-11-29 | Mass spectrometer and mass spectrometric method |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1215711B1 (en) |
| AT (2) | ATE368937T1 (en) |
| CA (1) | CA2343582C (en) |
| DE (2) | DE60126048T2 (en) |
| GB (1) | GB2382921B (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0029040D0 (en) * | 2000-11-29 | 2001-01-10 | Micromass Ltd | Orthogonal time of flight mass spectrometer |
| US7038197B2 (en) | 2001-04-03 | 2006-05-02 | Micromass Limited | Mass spectrometer and method of mass spectrometry |
| US7095015B2 (en) | 2001-10-22 | 2006-08-22 | Micromass Uk Limited | Mass spectrometer |
| EP1365437B1 (en) * | 2002-05-17 | 2014-08-20 | Micromass UK Limited | Mass spectrometer and method of mass spectrometry |
| GB2388704B (en) * | 2002-05-17 | 2004-08-11 | * Micromass Limited | Mass spectrometer and method of mass spectrometry |
| US20050080571A1 (en) * | 2003-10-10 | 2005-04-14 | Klee Matthew S. | Mass spectrometry performance enhancement |
| GB2428876B (en) * | 2004-04-05 | 2008-10-01 | Micromass Ltd | Mass spectrometer |
| EP1770754B1 (en) * | 2004-04-05 | 2014-06-11 | Micromass UK Limited | Mass spectrometer |
| JP2006032109A (en) * | 2004-07-15 | 2006-02-02 | Jeol Ltd | Vertical acceleration time-of-flight mass spectrometer |
| GB2467548B (en) | 2009-02-04 | 2013-02-27 | Nu Instr Ltd | Detection arrangements in mass spectrometers |
| GB0918630D0 (en) | 2009-10-23 | 2009-12-09 | Thermo Fisher Scient Bremen | Detection apparatus for detecting charged particles, methods for detecting charged particles and mass spectrometer |
| GB0918629D0 (en) | 2009-10-23 | 2009-12-09 | Thermo Fisher Scient Bremen | Detection apparatus for detecting charged particles, methods for detecting charged particles and mass spectometer |
| GB2486484B (en) | 2010-12-17 | 2013-02-20 | Thermo Fisher Scient Bremen | Ion detection system and method |
| CN109767971B (en) * | 2019-03-08 | 2024-08-13 | 昆山禾信质谱技术有限公司 | Two-dimensional ion beam deflection apparatus |
| CN118692889B (en) * | 2024-06-25 | 2025-10-03 | 四川紫璞科技有限责任公司 | A rare gas isotope mass spectrometer ion source |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5300774A (en) * | 1991-04-25 | 1994-04-05 | Applied Biosystems, Inc. | Time-of-flight mass spectrometer with an aperture enabling tradeoff of transmission efficiency and resolution |
| JP3385327B2 (en) * | 1995-12-13 | 2003-03-10 | 株式会社日立製作所 | 3D quadrupole mass spectrometer |
-
2001
- 2001-04-02 GB GB0228092A patent/GB2382921B/en not_active Expired - Lifetime
- 2001-04-06 CA CA2343582A patent/CA2343582C/en not_active Expired - Fee Related
- 2001-11-29 DE DE60126048T patent/DE60126048T2/en not_active Expired - Lifetime
- 2001-11-29 AT AT04010779T patent/ATE368937T1/en not_active IP Right Cessation
- 2001-11-29 AT AT01310018T patent/ATE352096T1/en not_active IP Right Cessation
- 2001-11-29 EP EP01310018A patent/EP1215711B1/en not_active Expired - Lifetime
- 2001-11-29 DE DE60129751T patent/DE60129751T2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1215711A2 (en) | 2002-06-19 |
| EP1215711B1 (en) | 2007-01-17 |
| ATE352096T1 (en) | 2007-02-15 |
| DE60126048T2 (en) | 2007-06-06 |
| GB2382921A (en) | 2003-06-11 |
| EP1215711A3 (en) | 2004-04-28 |
| GB2382921B (en) | 2003-10-29 |
| DE60129751T2 (en) | 2008-04-30 |
| CA2343582A1 (en) | 2002-05-29 |
| DE60126048D1 (en) | 2007-03-08 |
| ATE368937T1 (en) | 2007-08-15 |
| CA2343582C (en) | 2010-06-15 |
| GB0228092D0 (en) | 2003-01-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |