[go: up one dir, main page]

DE60128587D1 - Lactamverbindungen - Google Patents

Lactamverbindungen

Info

Publication number
DE60128587D1
DE60128587D1 DE60128587T DE60128587T DE60128587D1 DE 60128587 D1 DE60128587 D1 DE 60128587D1 DE 60128587 T DE60128587 T DE 60128587T DE 60128587 T DE60128587 T DE 60128587T DE 60128587 D1 DE60128587 D1 DE 60128587D1
Authority
DE
Germany
Prior art keywords
lactam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60128587T
Other languages
English (en)
Other versions
DE60128587T2 (de
Inventor
Thomas Mitchell Koenig
James Edmund Audia
David Mitchell
Stacey Leigh Mcdaniel
Lynne Ann Buccilli
Gary Lowell Engel
James Abraham Aikins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE60128587D1 publication Critical patent/DE60128587D1/de
Application granted granted Critical
Publication of DE60128587T2 publication Critical patent/DE60128587T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DE60128587T 2000-11-17 2001-11-02 Lactamverbindungen Expired - Lifetime DE60128587T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24965600P 2000-11-17 2000-11-17
US249656P 2000-11-17
PCT/US2001/027795 WO2002040451A2 (en) 2000-11-17 2001-11-02 Lactam compound

Publications (2)

Publication Number Publication Date
DE60128587D1 true DE60128587D1 (de) 2007-07-05
DE60128587T2 DE60128587T2 (de) 2008-01-31

Family

ID=22944436

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60128587T Expired - Lifetime DE60128587T2 (de) 2000-11-17 2001-11-02 Lactamverbindungen

Country Status (33)

Country Link
US (1) US20040248878A1 (de)
EP (1) EP1353910B1 (de)
JP (1) JP4116431B2 (de)
KR (1) KR20030045194A (de)
CN (2) CN100516047C (de)
AR (1) AR031356A1 (de)
AT (1) ATE362919T1 (de)
AU (2) AU2432102A (de)
BR (1) BR0115424A (de)
CA (1) CA2425497C (de)
CY (1) CY1106682T1 (de)
CZ (1) CZ20031340A3 (de)
DE (1) DE60128587T2 (de)
DK (1) DK1353910T3 (de)
DZ (1) DZ3454A1 (de)
EA (1) EA006919B1 (de)
EC (1) ECSP034598A (de)
ES (1) ES2286162T3 (de)
HR (1) HRP20030385A2 (de)
HU (1) HUP0301862A3 (de)
IL (1) IL155275A0 (de)
MX (1) MXPA03004250A (de)
MY (1) MY141607A (de)
NO (1) NO325217B1 (de)
PE (1) PE20020798A1 (de)
PL (1) PL211018B1 (de)
PT (1) PT1353910E (de)
SK (1) SK287794B6 (de)
SV (1) SV2003000741A (de)
TW (1) TWI235151B (de)
UA (1) UA77165C2 (de)
WO (1) WO2002040451A2 (de)
ZA (1) ZA200303411B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA74849C2 (en) * 2000-11-17 2006-02-15 Lilly Co Eli Lactam
KR100897642B1 (ko) 2002-12-20 2009-05-14 글락소 그룹 리미티드 신경 장애 치료용 벤즈아제핀 유도체
ES2295816T3 (es) 2003-01-14 2008-04-16 Arena Pharmaceuticals, Inc. Derivados arilo y heteroarilo 1,2,3-trisustituidos como moduladores del metabolismo, y profilaxis y tratamiento de transtornos relacionados con los mismos, tales como la diabetes y la hiperglucemia.
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
BRPI0610532A2 (pt) 2005-04-08 2010-06-29 Daiichi Sankyo Co Ltd derivado de piridilmetilsulfona
US8258302B2 (en) * 2006-01-31 2012-09-04 Api Corporation Method for producing benzazepinone
TW200920362A (en) 2007-09-11 2009-05-16 Daiichi Sankyo Co Ltd Alkylsulfone derivatives
FR2932800B1 (fr) * 2008-06-20 2015-02-20 Servier Lab Nouveau procede de synthese de la 7,8-dimethoxy-1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
EP2619198A1 (de) 2010-09-22 2013-07-31 Arena Pharmaceuticals, Inc. Modulatoren des gpr119-rezeptors und behandlung von damit assoziierten erkrankungen
KR101899014B1 (ko) 2012-01-06 2018-09-17 삼성전자주식회사 비엘디씨 모터의 제어 장치 및 그 방법
CN102690231B (zh) * 2012-04-11 2014-07-09 南京友杰医药科技有限公司 治疗阿尔茨海默病潜在药物司马西特的合成方法
JP6319912B2 (ja) 2013-04-19 2018-05-09 国立大学法人 岡山大学 アミロイドβ蛋白質により誘発される認知障害の治療剤およびアルツハイマー病治療薬、ならびにこれらに関連する治療方法および病態解析方法
PL3242666T3 (pl) 2015-01-06 2025-02-17 Arena Pharmaceuticals, Inc. Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1
JP6838744B2 (ja) 2015-06-22 2021-03-03 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１Ｐ１レセプター関連障害における使用のための（Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸（化合物１）の結晶性Ｌ−アルギニン塩
AU2018220521A1 (en) 2017-02-16 2019-09-05 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
KR102859841B1 (ko) 2018-06-06 2025-09-12 아레나 파마슈티칼스, 인크. S1p1 수용체와 관련된 병태의 치료 방법
WO2021195362A1 (en) 2020-03-26 2021-09-30 Seagen Inc. Methods of treating multiple myeloma

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69739236D1 (de) * 1996-12-23 2009-03-12 Lilly Co Eli Cycloalkyl-, lactam-, lacton- und verwandte verbindungen als hemmer der beta-amyloidpeptidfreisetzung
AU4707999A (en) * 1998-06-22 2000-01-10 Elan Pharmaceuticals, Inc. Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
EP1230220A1 (de) * 1999-11-09 2002-08-14 Eli Lilly And Company Beta-aminosäure-verbindungen zur hemmung der freisetzung von beta-amyloid-peptid und/oder seiner synthese

Also Published As

Publication number Publication date
DZ3454A1 (fr) 2002-05-23
ES2286162T3 (es) 2007-12-01
PL360991A1 (en) 2004-09-20
SV2003000741A (es) 2003-01-13
NO325217B1 (no) 2008-02-25
SK287794B6 (sk) 2011-10-04
NO20032215L (no) 2003-07-16
HUP0301862A2 (hu) 2003-09-29
CA2425497C (en) 2010-08-17
PE20020798A1 (es) 2002-09-06
JP2004521084A (ja) 2004-07-15
AU2432102A (en) 2002-05-27
ZA200303411B (en) 2004-08-02
CN1575282A (zh) 2005-02-02
ECSP034598A (es) 2003-06-25
SK5432003A3 (en) 2004-09-08
WO2002040451A3 (en) 2003-08-28
US20040248878A1 (en) 2004-12-09
HRP20030385A2 (en) 2003-08-31
AR031356A1 (es) 2003-09-17
CN101624372A (zh) 2010-01-13
DK1353910T3 (da) 2007-09-10
CN100516047C (zh) 2009-07-22
ATE362919T1 (de) 2007-06-15
EA200300579A1 (ru) 2003-12-25
NO20032215D0 (no) 2003-05-15
PL211018B1 (pl) 2012-03-30
MXPA03004250A (es) 2003-09-22
HUP0301862A3 (en) 2007-09-28
MY141607A (en) 2010-05-31
KR20030045194A (ko) 2003-06-09
UA77165C2 (en) 2006-11-15
AU2002224321B2 (en) 2006-10-19
CY1106682T1 (el) 2012-05-23
DE60128587T2 (de) 2008-01-31
EA006919B1 (ru) 2006-04-28
EP1353910B1 (de) 2007-05-23
IL155275A0 (en) 2003-11-23
CA2425497A1 (en) 2002-05-23
JP4116431B2 (ja) 2008-07-09
PT1353910E (pt) 2007-08-20
EP1353910A2 (de) 2003-10-22
BR0115424A (pt) 2003-10-21
TWI235151B (en) 2005-07-01
WO2002040451A2 (en) 2002-05-23
CZ20031340A3 (cs) 2004-06-16

Similar Documents

Publication Publication Date Title
NO20032236D0 (no) Laktamforbindelse
ATE290000T1 (de) Muscarinagonisten
ATE252099T1 (de) Biarylcarboxamide
DE10136334B8 (de) Hochgeschwindigkeitsvertikalresonatoroberflächenemissionslaser
ATE312098T1 (de) Thiazinoxazolidinon
ATA2932001A (de) Schneefräse
DE50100710D1 (de) Wischblatt
ATE262530T1 (de) Indolochinazolinone
ATE298751T1 (de) 7-oxopyridoryrimidine
DE60128587D1 (de) Lactamverbindungen
PT1268453E (pt) Metabolitos de agonista/antagonista de estrogenio
AR028336A1 (es) 4-hidroxi-tetrahidropiridonas fenilsubstituidas
DE10192638T1 (de) Bohrstangenladevorrichtung
ATE509008T1 (de) Sulfonylguanidine
DE10196064T1 (de) Halbleiterfotodektionsgerät
DE50011511D1 (de) Blowby-Heizung
AR027931A1 (es) Antitranspirantes
AR028061A1 (es) 2-enamino-cetonitrilos fenil-substituidos
PT1317179E (pt) Formulacoes de mesotriona
DE10052925B4 (de) Schaukelbett
ATE476423T1 (de) Benzoylpyridazine
DE50007634D1 (de) Kardioplegieballonkatheter
DE10085445T1 (de) Drahterodierbearbeitungseinrichtung
DE10195909T1 (de) Viehfüttervorrichtung
AR027982A1 (es) Aril- y heteroarilsulfonatos

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN