DE60125218D1 - Verfahren zur herstellung von humanem serumalbumin unter verwendung eines aufwarmschrittes - Google Patents
Verfahren zur herstellung von humanem serumalbumin unter verwendung eines aufwarmschrittesInfo
- Publication number
- DE60125218D1 DE60125218D1 DE60125218T DE60125218T DE60125218D1 DE 60125218 D1 DE60125218 D1 DE 60125218D1 DE 60125218 T DE60125218 T DE 60125218T DE 60125218 T DE60125218 T DE 60125218T DE 60125218 D1 DE60125218 D1 DE 60125218D1
- Authority
- DE
- Germany
- Prior art keywords
- serum albumin
- human serum
- heating step
- producing human
- contaminants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000008100 Human Serum Albumin Human genes 0.000 title abstract 3
- 108091006905 Human Serum Albumin Proteins 0.000 title abstract 3
- 238000010438 heat treatment Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000356 contaminant Substances 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000324030 | 2000-10-24 | ||
| JP2000324030A JP4798833B2 (ja) | 2000-10-24 | 2000-10-24 | 加熱処理工程を含むヒト血清アルブミンの製造方法 |
| PCT/JP2001/009336 WO2002034787A1 (fr) | 2000-10-24 | 2001-10-24 | Procede d"elaboration d"albumine de serum d"origine humaine comportant une etape de chauffage |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60125218D1 true DE60125218D1 (de) | 2007-01-25 |
| DE60125218T2 DE60125218T2 (de) | 2007-09-20 |
Family
ID=18801621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60125218T Expired - Lifetime DE60125218T2 (de) | 2000-10-24 | 2001-10-24 | Verfahren zur herstellung von humanen serumalbumin unter einbeziehen eines erwärmungsschrittes |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6908749B2 (de) |
| EP (1) | EP1329462B1 (de) |
| JP (1) | JP4798833B2 (de) |
| KR (1) | KR100839937B1 (de) |
| CN (1) | CN1313493C (de) |
| AT (1) | ATE348111T1 (de) |
| AU (1) | AU783638B2 (de) |
| CA (1) | CA2395590C (de) |
| DE (1) | DE60125218T2 (de) |
| DK (1) | DK1329462T3 (de) |
| ES (1) | ES2272548T3 (de) |
| WO (1) | WO2002034787A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE331735T1 (de) * | 2000-10-24 | 2006-07-15 | Chemo Sero Therapeut Res Inst | Verfahren zur monomerisierung von humanen serumalbumin-polymeren |
| ATE382057T1 (de) | 2001-06-28 | 2008-01-15 | Novo Nordisk As | Stabile formulierung von modifiziertem glp-1 |
| EP1567657A1 (de) * | 2002-11-26 | 2005-08-31 | Novo Nordisk A/S | Verfahren zur reinigung von aus fermentation erhaltenen produkt |
| GB0305989D0 (en) * | 2003-03-15 | 2003-04-23 | Delta Biotechnology Ltd | Agent |
| KR101308912B1 (ko) | 2003-06-03 | 2013-09-23 | 노보 노르디스크 에이/에스 | 안정화된 약학적 펩티드 조성물 |
| PL1633391T3 (pl) | 2003-06-03 | 2012-03-30 | Novo Nordisk As | Stabilizowane farmaceutycznie kompozycje peptydowe |
| SI3300721T2 (sl) | 2003-11-20 | 2025-05-30 | Novo Nordisk A/S | Peptidne formulacije, ki vsebujejo propilen glikol in ki so optimalne za proizvodnjo in uporabo v napravah za injiciranje |
| KR20070020204A (ko) * | 2004-01-20 | 2007-02-20 | 쥬리디컬 파운데이션 더 케모-세로-쎄라퓨틱 리서치 인스티튜트 | 2가 양이온 존재 하에서 가열 처리에 의한 인간 혈청알부민의 제조 방법 |
| PL1789434T3 (pl) | 2004-08-31 | 2014-07-31 | Novo Nordisk As | Zastosowanie tris(hydroksymetylo)aminometanu do stabilizacji peptydów, polipeptydów i białek |
| ES2458991T5 (en) | 2004-11-12 | 2025-10-14 | Novo Nordisk As | Stable formulations of insulinoptropic peptides |
| KR20080078010A (ko) | 2005-12-22 | 2008-08-26 | 체에스엘 베링 게엠베하 | 옥타노에이트-감소된 사람 알부민 |
| JP4936272B2 (ja) * | 2006-02-13 | 2012-05-23 | 独立行政法人科学技術振興機構 | バイオナノカプセルの効率的な精製法 |
| WO2009003061A1 (en) | 2007-06-25 | 2008-12-31 | Fred Hutchinson Cancer Research Center | Methods and compositions regarding polychalcogenide compositions |
| DK3429345T3 (da) | 2016-10-04 | 2019-11-25 | Albumedix Ltd | Anvendelser af rekombinant gær-afledt serumalbumin |
| CN106749623B (zh) * | 2016-12-09 | 2020-04-10 | 浙江大学 | 一种基于混合模式的扩张床吸附分离人血白蛋白方法 |
| MX2020001525A (es) | 2017-08-24 | 2020-03-20 | Novo Nordisk As | Composiciones de peptido similar al glucagon tipo 1 (glp-1) y sus usos. |
| EP4069200A1 (de) | 2019-12-04 | 2022-10-12 | Albumedix Ltd | Verfahren und damit hergestellte zusammensetzungen |
| IL294521A (en) | 2020-02-18 | 2022-09-01 | Novo Nordisk As | glp-1 compounds and their uses |
| US12161777B2 (en) | 2020-07-02 | 2024-12-10 | Davol Inc. | Flowable hemostatic suspension |
| US11739166B2 (en) | 2020-07-02 | 2023-08-29 | Davol Inc. | Reactive polysaccharide-based hemostatic agent |
| US12151045B2 (en) | 2020-12-28 | 2024-11-26 | Davol Inc. | Reactive dry powdered hemostatic materials comprising a protein and a multifunctionalized modified polyethylene glycol based crosslinking agent |
| WO2026009167A1 (en) * | 2024-07-02 | 2026-01-08 | Csl Behring Ag | A manufacturing process for albumin involving a heating step |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5071897A (de) * | 1973-11-07 | 1975-06-14 | ||
| US4025500A (en) * | 1974-06-06 | 1977-05-24 | Baxter Laboratories, Inc. | Preparation of albumin by fractionation of blood plasma or serum |
| IL66614A (en) | 1981-08-28 | 1985-09-29 | Genentech Inc | Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it |
| US5004688A (en) * | 1988-04-15 | 1991-04-02 | Phillips Petroleum Company | Purification of hepatitis proteins |
| JP2926722B2 (ja) | 1988-10-20 | 1999-07-28 | 吉富製薬株式会社 | アルブミン製剤及びその製造方法 |
| JPH0768137B2 (ja) * | 1989-06-15 | 1995-07-26 | 株式会社ミドリ十字 | アルブミン製剤及びその製法 |
| JPH0671434B2 (ja) * | 1989-09-18 | 1994-09-14 | 株式会社ミドリ十字 | ヒト血清アルブミンの製造方法 |
| JPH04234326A (ja) * | 1990-12-27 | 1992-08-24 | Green Cross Corp:The | アルブミン製剤及びその製法 |
| JPH0671434A (ja) | 1991-05-30 | 1994-03-15 | Tadahiro Omi | クリーンチャンバーの溶接方法 |
| US5440018A (en) * | 1992-05-20 | 1995-08-08 | The Green Cross Corporation | Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same |
| US5521287A (en) * | 1992-05-20 | 1996-05-28 | The Green Cross Corporation | Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same |
| JP3269504B2 (ja) * | 1992-07-08 | 2002-03-25 | 三菱ウェルファーマ株式会社 | ヒト血清アルブミンの製造方法 |
| US5728553A (en) | 1992-09-23 | 1998-03-17 | Delta Biotechnology Limited | High purity albumin and method of producing |
| JPH07126182A (ja) * | 1993-10-27 | 1995-05-16 | Green Cross Corp:The | 組換えヒト血清アルブミン製剤の滅菌方法 |
| JP3840674B2 (ja) * | 1994-08-31 | 2006-11-01 | 三菱ウェルファーマ株式会社 | 遺伝子操作に由来するヒト血清アルブミンの精製方法 |
| AU3868197A (en) * | 1996-08-23 | 1998-03-06 | Kirin Beer Kabushiki Kaisha | Yeast vectors and process for producing proteins with the use of the same |
| JP2885212B2 (ja) * | 1997-01-06 | 1999-04-19 | 吉富製薬株式会社 | 遺伝子操作由来のヒト血清アルブミンより得られる高純度ヒト血清アルブミン含有組成物 |
-
2000
- 2000-10-24 JP JP2000324030A patent/JP4798833B2/ja not_active Expired - Fee Related
-
2001
- 2001-10-24 KR KR1020027008242A patent/KR100839937B1/ko not_active Expired - Fee Related
- 2001-10-24 DK DK01978883T patent/DK1329462T3/da active
- 2001-10-24 CN CNB018056466A patent/CN1313493C/zh not_active Expired - Fee Related
- 2001-10-24 ES ES01978883T patent/ES2272548T3/es not_active Expired - Lifetime
- 2001-10-24 EP EP01978883A patent/EP1329462B1/de not_active Expired - Lifetime
- 2001-10-24 DE DE60125218T patent/DE60125218T2/de not_active Expired - Lifetime
- 2001-10-24 CA CA2395590A patent/CA2395590C/en not_active Expired - Fee Related
- 2001-10-24 AU AU10936/02A patent/AU783638B2/en not_active Ceased
- 2001-10-24 WO PCT/JP2001/009336 patent/WO2002034787A1/ja not_active Ceased
- 2001-10-24 AT AT01978883T patent/ATE348111T1/de not_active IP Right Cessation
-
2002
- 2002-06-20 US US10/175,103 patent/US6908749B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6908749B2 (en) | 2005-06-21 |
| DK1329462T3 (da) | 2007-01-22 |
| EP1329462B1 (de) | 2006-12-13 |
| AU1093602A (en) | 2002-05-06 |
| AU783638B2 (en) | 2005-11-17 |
| EP1329462A1 (de) | 2003-07-23 |
| KR20020065609A (ko) | 2002-08-13 |
| ATE348111T1 (de) | 2007-01-15 |
| CN1313493C (zh) | 2007-05-02 |
| WO2002034787A1 (fr) | 2002-05-02 |
| US20020182680A1 (en) | 2002-12-05 |
| ES2272548T3 (es) | 2007-05-01 |
| EP1329462A4 (de) | 2004-09-08 |
| CA2395590C (en) | 2012-12-11 |
| CN1406246A (zh) | 2003-03-26 |
| DE60125218T2 (de) | 2007-09-20 |
| CA2395590A1 (en) | 2002-05-02 |
| KR100839937B1 (ko) | 2008-06-20 |
| JP4798833B2 (ja) | 2011-10-19 |
| JP2002128796A (ja) | 2002-05-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |