DE60123444D1 - Verfahren zu herstellung von 2-(6-substituierte-1,3-dioxan-4-yl)essigsäurederivate - Google Patents

Verfahren zu herstellung von 2-(6-substituierte-1,3-dioxan-4-yl)essigsäurederivate

Info

Publication number: DE60123444D1
Authority: DE; Germany
Prior art keywords: substituted; formula; preparation; acetic acid; group
Prior art date: 2000-07-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60123444T

Other languages

English (en)

Other versions

DE60123444T2 (de

Inventor

Hermanus Kooistra

Josephus Zeegers

Daniel Mink

Maria Mulders

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

AstraZeneca UK Ltd

Original Assignee

AstraZeneca UK Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-07-19

Filing date

2001-07-12

Publication date

2006-11-09

2001-07-12 Application filed by AstraZeneca UK Ltd filed Critical AstraZeneca UK Ltd

2006-11-09 Application granted granted Critical

2006-11-09 Publication of DE60123444D1 publication Critical patent/DE60123444D1/de

2007-08-23 Publication of DE60123444T2 publication Critical patent/DE60123444T2/de

2021-07-13 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Catalysts (AREA)

DE60123444T 2000-07-19 2001-07-12 Verfahren zu herstellung von 2-(6-substituierte-1,3-dioxan-4-yl)essigsäurederivate Expired - Lifetime DE60123444T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
NL1015744A NL1015744C2 (nl)	2000-07-19	2000-07-19	Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
NL1015744		2000-07-19
PCT/NL2001/000535 WO2002006266A1 (en)	2000-07-19	2001-07-12	Process for the preparation of 2-(6-substituted-1,3-dioxane-4-yl)acetic acid derivatives

Publications (2)

Publication Number	Publication Date
DE60123444D1 true DE60123444D1 (de)	2006-11-09
DE60123444T2 DE60123444T2 (de)	2007-08-23

Family

ID=19771761

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60123444T Expired - Lifetime DE60123444T2 (de)	2000-07-19	2001-07-12	Verfahren zu herstellung von 2-(6-substituierte-1,3-dioxan-4-yl)essigsäurederivate

Country Status (29)

Country	Link
US (4)	US6870059B2 (de)
EP (2)	EP1317440B1 (de)
JP (2)	JP5006499B2 (de)
KR (3)	KR20080078925A (de)
CN (3)	CN1443183A (de)
AT (1)	ATE340790T1 (de)
AU (2)	AU7583001A (de)
BR (1)	BR0112535A (de)
CA (1)	CA2415963C (de)
CY (1)	CY1105881T1 (de)
CZ (1)	CZ302718B6 (de)
DE (1)	DE60123444T2 (de)
DK (1)	DK1317440T3 (de)
EE (1)	EE200300024A (de)
ES (2)	ES2272506T3 (de)
HU (1)	HUP0303166A3 (de)
IL (3)	IL153980A0 (de)
IS (2)	IS2386B (de)
MX (1)	MXPA03000498A (de)
NL (1)	NL1015744C2 (de)
NO (1)	NO328935B1 (de)
NZ (1)	NZ523703A (de)
PL (1)	PL207115B1 (de)
PT (1)	PT1317440E (de)
RU (1)	RU2266903C2 (de)
SK (2)	SK287755B6 (de)
UA (1)	UA77944C2 (de)
WO (1)	WO2002006266A1 (de)
ZA (1)	ZA200300478B (de)

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EP1323717A1 (de)	2001-12-27	2003-07-02	Dsm N.V.	Prozess für die Herstellung von 2-(6-Substituierten-1,3-Dioxan-4-yl) Essigsäure Derivaten
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GB0218781D0 (en) *	2002-08-13	2002-09-18	Astrazeneca Ab	Chemical process
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GB0312896D0 (en) *	2003-06-05	2003-07-09	Astrazeneca Ab	Chemical process
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UY28501A1 (es) *	2003-09-10	2005-04-29	Astrazeneca Uk Ltd	Compuestos químicos
GB0321827D0 (en) *	2003-09-18	2003-10-15	Astrazeneca Uk Ltd	Chemical compounds
GB0324791D0 (en) *	2003-10-24	2003-11-26	Astrazeneca Ab	Chemical process
DE10352659B4 (de) *	2003-11-11	2007-09-13	Ratiopharm Gmbh	Verfahren zur Herstellung von Statinen und Tetrahydropyranonderivate zur Verwendung in dem Verfahren
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GB2482525A (en) *	2010-08-05	2012-02-08	Phoenix Chemicals Ltd	A process for the production of acyloxymethyldioxanylacetic derivatives
EP2614057B1 (de)	2010-09-09	2015-10-21	DSM Sinochem Pharmaceuticals Netherlands B.V.	Salze aus 7-amino-3,5-dihydroxyheptanonsäureestern
EP2616454B1 (de)	2010-09-16	2015-04-15	DSM Sinochem Pharmaceuticals Netherlands B.V.	Hexansäureester als zwischenprodukte zur herstellung von atorvastatin
US9150562B2 (en)	2011-01-18	2015-10-06	Dsm Sinochem Pharmaceuticals Netherlands B.V.	Process for the preparation of diol sulfones
CN103313984B (zh)	2011-01-18	2016-01-13	中化帝斯曼制药有限公司荷兰公司	甲基四唑硫化物和砜
WO2012098049A1 (en)	2011-01-18	2012-07-26	Dsm Sinochem Pharmaceuticals Netherlands B.V.	Process for the preparation of statins in the presence of base
EP2788342B1 (de)	2011-12-09	2018-01-24	DSM Sinochem Pharmaceuticals Netherlands B.V.	Verfahren zur herstellung eines statinvorläufers
WO2013083719A1 (en) *	2011-12-09	2013-06-13	Dsm Sinochem Pharmaceuticals Netherlands B.V.	Process for the preparation of a thioprecursor for statins
JP6065862B2 (ja) *	2013-04-10	2017-01-25	信越化学工業株式会社	パターン形成方法、レジスト組成物、高分子化合物及び単量体
WO2014203045A1 (en)	2013-06-20	2014-12-24	Lupin Limited	A novel, green and cost effective process for synthesis of tert-butyl (3r,5s)-6-oxo-3,5-dihydroxy-3,5-o-isopropylidene-hexanoate
CN105624127B (zh) *	2014-10-28	2019-07-26	上海弈柯莱生物医药科技有限公司	一种葡萄糖脱氢酶及其在合成他汀类药物中间体中的应用

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2000
- 2000-07-19 NL NL1015744A patent/NL1015744C2/nl not_active IP Right Cessation
2001
- 2001-07-12 SK SK35-2003A patent/SK287755B6/sk not_active IP Right Cessation
- 2001-07-12 DK DK01953373T patent/DK1317440T3/da active
- 2001-07-12 PL PL359332A patent/PL207115B1/pl not_active IP Right Cessation
- 2001-07-12 AU AU7583001A patent/AU7583001A/xx active Pending
- 2001-07-12 US US10/333,351 patent/US6870059B2/en not_active Expired - Lifetime
- 2001-07-12 IL IL15398001A patent/IL153980A0/xx active IP Right Grant
- 2001-07-12 NZ NZ523703A patent/NZ523703A/en not_active IP Right Cessation
- 2001-07-12 KR KR1020087019878A patent/KR20080078925A/ko not_active Ceased
- 2001-07-12 AU AU2001275830A patent/AU2001275830B2/en not_active Ceased
- 2001-07-12 JP JP2002512170A patent/JP5006499B2/ja not_active Expired - Lifetime
- 2001-07-12 CN CN01812999A patent/CN1443183A/zh not_active Withdrawn
- 2001-07-12 EE EEP200300024A patent/EE200300024A/xx unknown
- 2001-07-12 AT AT01953373T patent/ATE340790T1/de active
- 2001-07-12 CA CA002415963A patent/CA2415963C/en not_active Expired - Fee Related
- 2001-07-12 BR BR0112535-4A patent/BR0112535A/pt not_active IP Right Cessation
- 2001-07-12 KR KR1020077027471A patent/KR20070121063A/ko not_active Ceased
- 2001-07-12 SK SK123-2010A patent/SK287756B6/sk not_active IP Right Cessation
- 2001-07-12 CZ CZ20030163A patent/CZ302718B6/cs not_active IP Right Cessation
- 2001-07-12 CN CNB2005100657442A patent/CN100378091C/zh not_active Expired - Lifetime
- 2001-07-12 RU RU2003104825/04A patent/RU2266903C2/ru not_active IP Right Cessation
- 2001-07-12 WO PCT/NL2001/000535 patent/WO2002006266A1/en not_active Ceased
- 2001-07-12 EP EP01953373A patent/EP1317440B1/de not_active Expired - Lifetime
- 2001-07-12 PT PT01953373T patent/PT1317440E/pt unknown
- 2001-07-12 HU HU0303166A patent/HUP0303166A3/hu unknown
- 2001-07-12 DE DE60123444T patent/DE60123444T2/de not_active Expired - Lifetime
- 2001-07-12 EP EP06010837A patent/EP1700854B1/de not_active Expired - Lifetime
- 2001-07-12 MX MXPA03000498A patent/MXPA03000498A/es active IP Right Grant
- 2001-07-12 CN CN2007101118797A patent/CN101081842B/zh not_active Expired - Lifetime
- 2001-07-12 KR KR1020027017684A patent/KR100865016B1/ko not_active Expired - Fee Related
- 2001-07-12 ES ES01953373T patent/ES2272506T3/es not_active Expired - Lifetime
- 2001-07-12 ES ES06010837T patent/ES2387313T3/es not_active Expired - Lifetime
- 2001-12-07 UA UA2003010456A patent/UA77944C2/uk unknown
2003
- 2003-01-03 NO NO20030025A patent/NO328935B1/no not_active IP Right Cessation
- 2003-01-15 IS IS6680A patent/IS2386B/is unknown
- 2003-01-16 IL IL153980A patent/IL153980A/en not_active IP Right Cessation
- 2003-01-17 ZA ZA200300478A patent/ZA200300478B/en unknown
2005
- 2005-02-07 US US11/053,090 patent/US7642363B2/en not_active Expired - Lifetime
2006
- 2006-08-31 IL IL177824A patent/IL177824A0/en not_active IP Right Cessation
- 2006-12-21 CY CY20061101848T patent/CY1105881T1/el unknown
2007
- 2007-11-15 IS IS8690A patent/IS8690A/is unknown
2009
- 2009-11-24 US US12/625,156 patent/US7989643B2/en not_active Expired - Fee Related
2011
- 2011-06-22 US US13/166,607 patent/US20110251406A1/en not_active Abandoned
- 2011-12-06 JP JP2011267056A patent/JP2012111757A/ja active Pending

Also Published As

Publication number	Publication date
AU7583001A (en)	2002-01-30
BR0112535A (pt)	2003-07-01
CN101081842B (zh)	2012-01-04
ES2387313T3 (es)	2012-09-20
ATE340790T1 (de)	2006-10-15
JP5006499B2 (ja)	2012-08-22
NL1015744C2 (nl)	2002-01-22
US7989643B2 (en)	2011-08-02
SK287755B6 (sk)	2011-08-04
NO328935B1 (no)	2010-06-21
RU2266903C2 (ru)	2005-12-27
IS2386B (is)	2008-07-15
EP1700854A1 (de)	2006-09-13
NO20030025L (no)	2003-01-03
PL207115B1 (pl)	2010-11-30
US20050148785A1 (en)	2005-07-07
EP1700854B1 (de)	2012-05-23
JP2004504315A (ja)	2004-02-12
IS8690A (is)	2007-11-15
HUP0303166A3 (en)	2005-11-28
IL153980A0 (en)	2003-07-31
US20100136339A1 (en)	2010-06-03
CN100378091C (zh)	2008-04-02
CY1105881T1 (el)	2011-02-02
HUP0303166A2 (hu)	2003-12-29
HK1097260A1 (en)	2007-06-22
IL177824A0 (en)	2006-12-31
JP2012111757A (ja)	2012-06-14
US7642363B2 (en)	2010-01-05
KR20030040224A (ko)	2003-05-22
DK1317440T3 (da)	2007-01-08
KR20080078925A (ko)	2008-08-28
ZA200300478B (en)	2004-01-26
EP1317440A1 (de)	2003-06-11
ES2272506T3 (es)	2007-05-01
DE60123444T2 (de)	2007-08-23
IL153980A (en)	2006-10-05
EE200300024A (et)	2004-10-15
WO2002006266A1 (en)	2002-01-24
NO20030025D0 (no)	2003-01-03
CZ302718B6 (cs)	2011-09-21
AU2001275830B2 (en)	2006-07-20
UA77944C2 (en)	2007-02-15
CA2415963A1 (en)	2002-01-24
CZ2003163A3 (cs)	2003-05-14
CA2415963C (en)	2008-02-26
EP1317440B1 (de)	2006-09-27
US6870059B2 (en)	2005-03-22
KR20070121063A (ko)	2007-12-26
NZ523703A (en)	2004-08-27
PT1317440E (pt)	2007-01-31
IS6680A (is)	2003-01-15
US20110251406A1 (en)	2011-10-13
PL359332A1 (en)	2004-08-23
US20030158426A1 (en)	2003-08-21
CN1443183A (zh)	2003-09-17
KR100865016B1 (ko)	2008-10-23
MXPA03000498A (es)	2003-06-24
SK352003A3 (en)	2003-05-02
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SK287756B6 (sk)	2011-08-04
CN101081842A (zh)	2007-12-05

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