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DE60115944D1 - Feste zusammensetzungen für orale verabreichung die nicht-hygroskopische salze von l-karnitin und alkanoyl-l-karnitin mit taurinchlorid enthalten - Google Patents

Feste zusammensetzungen für orale verabreichung die nicht-hygroskopische salze von l-karnitin und alkanoyl-l-karnitin mit taurinchlorid enthalten

Info

Publication number
DE60115944D1
DE60115944D1 DE60115944T DE60115944T DE60115944D1 DE 60115944 D1 DE60115944 D1 DE 60115944D1 DE 60115944 T DE60115944 T DE 60115944T DE 60115944 T DE60115944 T DE 60115944T DE 60115944 D1 DE60115944 D1 DE 60115944D1
Authority
DE
Germany
Prior art keywords
carnitine
chloride
alkanoyl
solid compositions
oral administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60115944T
Other languages
English (en)
Other versions
DE60115944T2 (de
Inventor
Ornella Tinti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of DE60115944D1 publication Critical patent/DE60115944D1/de
Application granted granted Critical
Publication of DE60115944T2 publication Critical patent/DE60115944T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/24—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A23L33/22—Comminuted fibrous parts of plants, e.g. bagasse or pulp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Botany (AREA)
  • Polymers & Plastics (AREA)
  • Obesity (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Fodder In General (AREA)
DE60115944T 2000-10-31 2001-09-28 Feste zusammensetzungen für orale verabreichung die nicht-hygroskopische salze von l-karnitin und alkanoyl-l-karnitin mit taurinchlorid enthalten Expired - Lifetime DE60115944T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM20000567 2000-10-31
IT2000RM000567A IT1317924B1 (it) 2000-10-31 2000-10-31 Composizioni solide atte alla somministrazione orale comprendenti salinon igroscopici della l-carnitina e delle alcanoil l-carnitine con
PCT/IT2001/000503 WO2002036543A1 (en) 2000-10-31 2001-09-28 Solid compositions suitable for oral administration containing non-hygroscopic salts of l-carnitine and the alkanoyl l-carnitines with taurine chloride and glycine chloride

Publications (2)

Publication Number Publication Date
DE60115944D1 true DE60115944D1 (de) 2006-01-19
DE60115944T2 DE60115944T2 (de) 2006-06-29

Family

ID=11454973

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60115944T Expired - Lifetime DE60115944T2 (de) 2000-10-31 2001-09-28 Feste zusammensetzungen für orale verabreichung die nicht-hygroskopische salze von l-karnitin und alkanoyl-l-karnitin mit taurinchlorid enthalten

Country Status (24)

Country Link
US (1) US7858820B2 (de)
EP (1) EP1330428B1 (de)
JP (1) JP4181406B2 (de)
KR (1) KR100764155B1 (de)
CN (1) CN1219748C (de)
AT (1) ATE312810T1 (de)
AU (2) AU9589301A (de)
BR (1) BRPI0115019B1 (de)
CA (1) CA2427482C (de)
CY (1) CY1106062T1 (de)
CZ (1) CZ302802B6 (de)
DE (1) DE60115944T2 (de)
DK (1) DK1330428T3 (de)
ES (1) ES2253430T3 (de)
HU (1) HU229989B1 (de)
IT (1) IT1317924B1 (de)
MX (1) MXPA03003799A (de)
NZ (1) NZ525333A (de)
PL (1) PL205801B1 (de)
RU (1) RU2270191C2 (de)
SI (1) SI1330428T1 (de)
SK (1) SK287133B6 (de)
WO (1) WO2002036543A1 (de)
ZA (1) ZA200303328B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005031705A1 (de) * 2005-07-05 2007-01-18 Henkel Kgaa Mittel, enthaltend L-Carnitin oder L-Carnitinderivate und mindestens eine weitere Substanz ausgewählt aus Taurin und dessen Derivaten und mindestens einem Wirkstoff, erhältlich aus Pflanzen der Gattung Echinacea
KR101007927B1 (ko) 2008-12-24 2011-01-14 주식회사 셀트리온제약 시부트라민-ｌ-카르니틴 다이술폰산염, 이의 제조방법 및 이를 포함하는 약제학적 조성물
JP5451558B2 (ja) * 2010-08-27 2014-03-26 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ 美容活性成分の送達に有用なゲル
CN104276986B (zh) * 2013-07-12 2016-07-06 辽宁科硕营养科技有限公司 左旋肉碱牛磺酸盐的制备方法
JP6473352B2 (ja) * 2015-03-10 2019-02-20 利幸 糸井 虚血性疾患治療薬
CN107325013B (zh) * 2016-04-28 2019-04-12 辽宁科硕营养科技股份有限公司 一种合成甘氨酸丙酰左旋肉碱盐酸盐的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0150688B1 (de) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salze von L-Carnitin und Alkanoyl-L-Carnitinen sowie Verfahren zur Herstellung derselben
CA2030310A1 (en) * 1989-12-22 1991-06-23 Ronald E. Macleay Derivatives of n-hals-substituted amic acid hydrazides
IT1291126B1 (it) * 1997-04-01 1998-12-29 Sigma Tau Ind Farmaceuti Composizioni solide atte alla somministrazione orale comprendenti sali non igroscopici della l-carnitina e delle alcanoil l-carnitine
IT1306147B1 (it) * 1999-05-28 2001-05-30 Biosalts Srl Derivati di principi attivi ad attivita' terapeutica e/o nutrizionalee composizioni atte alla somministrazione orale contenenti tali

Also Published As

Publication number Publication date
WO2002036543A1 (en) 2002-05-10
HK1061230A1 (en) 2004-09-10
DK1330428T3 (da) 2006-04-18
KR20030059211A (ko) 2003-07-07
CN1219748C (zh) 2005-09-21
CZ20031041A3 (cs) 2003-08-13
SK287133B6 (sk) 2010-01-07
IT1317924B1 (it) 2003-07-15
CY1106062T1 (el) 2011-06-08
US7858820B2 (en) 2010-12-28
CA2427482A1 (en) 2002-05-10
BRPI0115019B1 (pt) 2015-10-06
KR100764155B1 (ko) 2007-10-08
PL205801B1 (pl) 2010-05-31
SK5012003A3 (en) 2003-11-04
RU2270191C2 (ru) 2006-02-20
CN1473144A (zh) 2004-02-04
HUP0302294A3 (en) 2005-05-30
JP4181406B2 (ja) 2008-11-12
MXPA03003799A (es) 2004-04-20
ITRM20000567A1 (it) 2002-05-01
AU9589301A (en) 2002-05-15
ATE312810T1 (de) 2005-12-15
CZ302802B6 (cs) 2011-11-16
EP1330428A1 (de) 2003-07-30
HU229989B1 (hu) 2015-04-28
SI1330428T1 (sl) 2006-04-30
CA2427482C (en) 2010-04-27
AU2001295893B2 (en) 2006-11-30
ES2253430T3 (es) 2006-06-01
BR0115019A (pt) 2003-12-23
US20040024061A1 (en) 2004-02-05
JP2004513107A (ja) 2004-04-30
ITRM20000567A0 (it) 2000-10-31
ZA200303328B (en) 2004-03-09
EP1330428B1 (de) 2005-12-14
PL364823A1 (en) 2004-12-27
HUP0302294A2 (hu) 2003-10-28
NZ525333A (en) 2004-06-25
DE60115944T2 (de) 2006-06-29

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