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DE60110902D1 - Amidino-verbindung sowie salze davon verwendbar als hemmstoffe der stickstoffmonoxid-synthase - Google Patents

Amidino-verbindung sowie salze davon verwendbar als hemmstoffe der stickstoffmonoxid-synthase

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Publication number
DE60110902D1
DE60110902D1 DE60110902T DE60110902T DE60110902D1 DE 60110902 D1 DE60110902 D1 DE 60110902D1 DE 60110902 T DE60110902 T DE 60110902T DE 60110902 T DE60110902 T DE 60110902T DE 60110902 D1 DE60110902 D1 DE 60110902D1
Authority
DE
Germany
Prior art keywords
nitrogen
salts
amidino compound
monoxide synthase
nitrogen monoxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60110902T
Other languages
English (en)
Other versions
DE60110902T2 (de
Inventor
Keith Webber
K Awasthi
A Bergmanis
C Durley
S Ganser
J Hagen
E Hallinan
W Hansen
S Hickory
E Moormann
S Pitzele
A Promo
R Schartman
S Snyder
Mahima Trivedi
Sofya Tsymbalov
W Gary Phillips
Embse Richard Vonder
Gopichand Yalamanchili
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia LLC
Original Assignee
Pharmacia LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia LLC filed Critical Pharmacia LLC
Publication of DE60110902D1 publication Critical patent/DE60110902D1/de
Application granted granted Critical
Publication of DE60110902T2 publication Critical patent/DE60110902T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
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