DE60043424D1 - Rhodococcus-stamm, nitrilase-gen aus rhodococcus, nitrilhydratas-gen und amidase-gen und verfahren zur herstellung carboxylsäuren unter deren verwendung - Google Patents

Rhodococcus-stamm, nitrilase-gen aus rhodococcus, nitrilhydratas-gen und amidase-gen und verfahren zur herstellung carboxylsäuren unter deren verwendung

Info

Publication number: DE60043424D1
Authority: DE; Germany
Prior art keywords: gene; rhodococcus; carboxylic acids; nitrilhydratas; production
Prior art date: 1999-10-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60043424T

Other languages

English (en)

Inventor

Hirobumi Aoki

Harumi Kamachi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Resonac Holdings Corp

Original Assignee

Showa Denko KK

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-26

Filing date

2000-10-25

Publication date

2010-01-14

1999-10-26 Priority claimed from JP30321299A external-priority patent/JP2001120290A/ja

2000-01-26 Priority claimed from JP2000021797A external-priority patent/JP2001136977A/ja

2000-04-10 Priority claimed from JP2000107855A external-priority patent/JP2001292772A/ja

2000-10-25 Application filed by Showa Denko KK filed Critical Showa Denko KK

2010-01-14 Application granted granted Critical

2010-01-14 Publication of DE60043424D1 publication Critical patent/DE60043424D1/de

2020-10-26 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
Virology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)

DE60043424T 1999-10-26 2000-10-25 Rhodococcus-stamm, nitrilase-gen aus rhodococcus, nitrilhydratas-gen und amidase-gen und verfahren zur herstellung carboxylsäuren unter deren verwendung Expired - Lifetime DE60043424D1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP30321299A JP2001120290A (ja)	1999-10-26	1999-10-26	微生物によるカルボン酸類の製法
JP2000021797A JP2001136977A (ja)	1999-09-02	2000-01-26	ロドコッカス属細菌由来のニトリラーゼ遺伝子
JP2000107855A JP2001292772A (ja)	2000-04-10	2000-04-10	ロドコッカス属細菌由来のニトリルヒドラターゼ遺伝子およびアミダーゼ遺伝子
PCT/JP2000/007464 WO2001030994A1 (en)	1999-10-26	2000-10-25	Novel rhodococcus, rhodococcus-origin nitrilase gene, nitrilehydratase gene and amidase gene and process for producing carboxylic acids by using the same

Publications (1)

Publication Number	Publication Date
DE60043424D1 true DE60043424D1 (de)	2010-01-14

Family

ID=27338591

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60043424T Expired - Lifetime DE60043424D1 (de)	1999-10-26	2000-10-25	Rhodococcus-stamm, nitrilase-gen aus rhodococcus, nitrilhydratas-gen und amidase-gen und verfahren zur herstellung carboxylsäuren unter deren verwendung

Country Status (11)

Country	Link
US (1)	US7118898B1 (de)
EP (1)	EP1142997B1 (de)
KR (1)	KR100540991B1 (de)
CN (1)	CN1340101A (de)
AT (1)	ATE450607T1 (de)
AU (1)	AU7957100A (de)
CA (1)	CA2356741C (de)
DE (1)	DE60043424D1 (de)
EA (1)	EA200100718A1 (de)
NO (1)	NO328690B1 (de)
WO (1)	WO2001030994A1 (de)

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JP4584242B2 (ja)	2003-02-27	2010-11-17	ビーエーエスエフソシエタス・ヨーロピア	改変されたニトリラーゼおよびカルボン酸の製造方法におけるその使用
DE10315376B4 (de) *	2003-04-03	2005-07-14	Stockhausen Gmbh	Verfahren zur Kultivierung des Nitrilhydratase-produzierenden Stammes RHODOCOCCUS RHODOCHROUS M33
SG128683A1 (en) *	2003-10-31	2007-01-30	Daiichi Fine Chem Co Ltd	Novel plasmids and utilization thereof
AU2005248259B2 (en) *	2004-05-26	2010-07-08	Mitsubishi Chemical Corporation	Improved nitrile hydratase
US7148051B2 (en) *	2004-08-16	2006-12-12	E. I. Du Pont De Nemours And Company	Production of 3-hydroxycarboxylic acid using nitrilase
US20090130726A1 (en) *	2005-09-22	2009-05-21	Andrew Wells	Process for converting aromatic halo-substituted dinitriles into halo-substituted cyanocarboxylic acids
US20100267100A1 (en) *	2007-03-21	2010-10-21	Ling Hua	Enzymatic synthesis of optically pure beta-hydroxy carboxylic acids and their derivatives
US20090004720A1 (en) *	2007-06-26	2009-01-01	Ling Hua	Smart Biocatalysts For Organic Synthesis
WO2009117843A1 (zh) *	2008-03-24	2009-10-01	清华大学	敲除酰胺酶基因的产腈水合酶工程菌及其构建方法和应用
CN101434926B (zh) *	2008-10-31	2010-08-11	云南大学	一株可代谢尼古丁的红球菌及其应用
CN101875907B (zh) *	2009-04-28	2013-07-10	上海市农药研究所	一种可水解3-羟基丁腈的微生物菌株
KR101223663B1 (ko)	2011-01-26	2013-01-21	재단법인 경북해양바이오산업연구원	나이트릴레이즈 ｖｍｎ１을 이용한 카르복실산의 제조방법
CN103757068B (zh) *	2014-01-10	2016-06-29	江苏清泉化学股份有限公司	一种苯甲酸衍生物的制备方法
CN105420154B (zh) *	2015-12-16	2020-03-17	清华大学	双基因敲除重组红球菌、构建方法及其应用
AU2017388945B2 (en) *	2016-12-28	2021-06-03	Mitsui Chemicals, Inc.	Mutant nitrile hydratase, nucleic acid coding said mutant nitrile hydratase, expression vector and transformant including said nucleic acid, production method for said mutant nitrile hydratase, and production method for amide compound
CN109136301A (zh) *	2018-09-19	2019-01-04	安徽瑞邦生物科技有限公司	一种水解制备烟酸的方法
CN109295124A (zh) *	2018-10-24	2019-02-01	张刘兵	一种水解制备烟酸的方法
CN110205315B (zh) *	2019-05-30	2021-01-01	中国石油大学(华东)	腈水解酶XiNit2及其编码基因和应用
CN110499274B (zh) *	2019-09-18	2021-11-23	清华大学	一种基因工程红球菌及其构建方法与应用
CN111378640A (zh) *	2020-03-12	2020-07-07	东莞市东阳光生物合成药有限公司	制备右旋酰胺酮洛芬的方法
WO2024197480A1 (zh) *	2023-03-24	2024-10-03	浙江九洲药业股份有限公司	一种利用酰胺酶合成右旋酮洛芬的方法
CN119162158B (zh) *	2024-11-21	2025-03-14	百葵锐(天津)生物科技有限公司	一种在红球菌中高效表达酰胺酶的方法及其应用

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US4629700A (en)	1983-11-30	1986-12-16	Standard Oil Company (Indiana)	Selective conversion of cyano compounds to amides and carboxylic acids
CN85107055A (zh)	1984-10-01	1986-06-10	诺沃工业联合股票公司	酶促工艺方法
AU627648B2 (en)	1990-02-28	1992-08-27	Teruhiko Beppu	Dna fragment encoding a polypeptide having nitrile hydratase activity, a transformant containing the gene and a process for the production of amides using the transformant
EP0502476B1 (de) *	1991-03-04	2001-07-18	Mitsubishi Rayon Co., Ltd.	Hybrid-Plasmid-Vektoren, die für Nitril-abbauende Enzyme kodierende Gene enthalten und Verfahren zur Herstellung von Amiden und Säuren
JPH0799980A (ja)	1993-10-05	1995-04-18	Japan Energy Corp	ニトリラーゼ活性を有するポリペプチドをコードする遺伝子ｄｎａ、およびこれを含有する形質転換体によるニトリル類からカルボン酸の製造法
RU2053300C1 (ru) *	1993-12-17	1996-01-27	Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов	Штамм бактерий rhodococcus rhodochrous - продуцент нитрилгидратазы
WO1997006248A1 (en)	1995-08-09	1997-02-20	Allied Colloids Limited	Processes for the production of amidase
JPH11513255A (ja)	1995-10-06	1999-11-16	イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー	立体特異的ニトリルヒドラターゼおよびアミダーゼ酵素をコードする核酸断片、ならびにキラルアミドおよび酸の生産に有用なそれら酵素を発現する組換え微生物
DE19743683A1 (de) *	1997-10-02	1999-04-08	Basf Ag	Verfahren zur Änderung der Substratspezifität von Enzymen
JP2001069978A (ja) *	1999-09-02	2001-03-21	Showa Denko Kk	ロドコッカス属細菌由来のニトリルヒドラターゼ遺伝子およびアミダーゼ遺伝子
JP2001136977A (ja)	1999-09-02	2001-05-22	Showa Denko Kk	ロドコッカス属細菌由来のニトリラーゼ遺伝子
JP2001292772A (ja)	2000-04-10	2001-10-23	Showa Denko Kk	ロドコッカス属細菌由来のニトリルヒドラターゼ遺伝子およびアミダーゼ遺伝子
DE10010149A1 (de)	2000-03-03	2001-09-06	Basf Ag	Nitrilase aus Rhodococcus rhodochrous NCIMB 11216

2000
- 2000-10-25 DE DE60043424T patent/DE60043424D1/de not_active Expired - Lifetime
- 2000-10-25 KR KR1020017008153A patent/KR100540991B1/ko not_active Expired - Fee Related
- 2000-10-25 AU AU79571/00A patent/AU7957100A/en not_active Abandoned
- 2000-10-25 CN CN00803733A patent/CN1340101A/zh active Pending
- 2000-10-25 EP EP00970065A patent/EP1142997B1/de not_active Expired - Lifetime
- 2000-10-25 AT AT00970065T patent/ATE450607T1/de not_active IP Right Cessation
- 2000-10-25 CA CA2356741A patent/CA2356741C/en not_active Expired - Fee Related
- 2000-10-25 EA EA200100718A patent/EA200100718A1/ru unknown
- 2000-10-25 WO PCT/JP2000/007464 patent/WO2001030994A1/ja not_active Ceased
- 2000-10-25 US US09/869,142 patent/US7118898B1/en not_active Expired - Fee Related
2001
- 2001-06-26 NO NO20013209A patent/NO328690B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP1142997A1 (de)	2001-10-10
CN1340101A (zh)	2002-03-13
EP1142997B1 (de)	2009-12-02
KR20010084883A (ko)	2001-09-06
NO328690B1 (no)	2010-04-26
NO20013209D0 (no)	2001-06-26
EP1142997A4 (de)	2004-03-24
CA2356741A1 (en)	2001-05-03
AU7957100A (en)	2001-05-08
WO2001030994A1 (en)	2001-05-03
US7118898B1 (en)	2006-10-10
CA2356741C (en)	2011-01-25
KR100540991B1 (ko)	2006-01-10
NO20013209L (no)	2001-07-03
ATE450607T1 (de)	2009-12-15
EA200100718A1 (ru)	2001-12-24

Publication	Publication Date	Title
DE60043424D1 (de)	2010-01-14	Rhodococcus-stamm, nitrilase-gen aus rhodococcus, nitrilhydratas-gen und amidase-gen und verfahren zur herstellung carboxylsäuren unter deren verwendung
Chen et al.	2009	Microbial transformation of nitriles to high-value acids or amides
ID29136A (id)	2001-08-02	Suatu proses untuk pembuatan asam karboksilat kiral dari nitril dengan menggunakan suatu nitrilase atau mikroorganisme yang terdiri dari suatu gen untuk nitrilase
Wang et al.	2002	Enzymatic desymmetrization of 3-alkyl-and 3-arylglutaronitriles, a simple and convenient approach to optically active 4-amino-3-phenylbutanoic acids
ATE435278T1 (de)	2009-07-15	Modifizierte nitrilasen und deren verwendung in verfahren zur herstellung von carbonsäuren
US8945887B2 (en)	2015-02-03	Whole cell biocatalyst
AU2002333878A1 (en)	2003-05-12	A process for the production of l-amino acids using strains of the enterobacteriaceae family which contain an enhanced fadr or iclr gene
DE102008029302B4 (de)	2016-08-11	Biotechnologische Herstellung von Acrylsäure
BR0108883A (pt)	2003-04-29	Sequência de ácido nucleico isolado, construção de ácido nucleico, vetor, microorganismo recombinante, e, processo para a preparação de ácidos carboxìlicos quirais ou aquirais
JPWO2011078172A1 (ja)	2013-05-09	光学活性３−置換グルタル酸モノアミドの製造法
Effenberger et al.	1998	Chemo-and enantioselective hydrolysis of nitriles and acid amides, respectively, with resting cells of Rhodococcus sp. C3II and Rhodococcus erythropolis MP50
Vink et al.	2006	Nitrile hydrolysis activity of Rhodococcus erythropolis NCIMB 11540 whole cells
Brady	2013	Biocatalytic hydrolysis of nitriles
JP4319260B2 (ja)	2009-08-26	エステラーゼ遺伝子及びその利用
US7198926B2 (en)	2007-04-03	Preparation of (E)- and (Z)-2-methyl-2-butenoic acids
JPWO2012176715A1 (ja)	2015-02-23	１−アミノ−２−ビニルシクロプロパンカルボン酸アミドおよびその塩、ならびにその製造方法
AU2009303012A1 (en)	2010-04-15	Method for preparing epsilon-caprolactam from N-acyl-6-aminocaproic acid
DK1409688T3 (da)	2007-09-17	Nukleinsyresekvenser der koder for enantioselektive amidaser
JP3732535B2 (ja)	2006-01-05	光学活性α−メチルアルカンジカルボン酸−ω−モノエステル及びその対掌体ジエステルを製造する方法
Yamada	1998	Screening of novel enzymes for the production of useful compounds
KR20030033013A (ko)	2003-04-26	시아노카르복실산 에스테르로부터 디카르복실산모노에스테르의 제조
JPH04341185A (ja)	1992-11-27	新規ニトリラーゼ
JPH11318486A (ja)	1999-11-24	光学活性シクロプロパンカルボン酸の製造法
JPH11318483A (ja)	1999-11-24	光学活性シクロプロパンカルボン酸の製造法
WO2011013340A1 (ja)	2011-02-03	光学活性３－置換グルタル酸モノアミドの製造法

Legal Events

Date	Code	Title	Description
2010-12-23	8364	No opposition during term of opposition