DE60026161D1 - Amidin-derivate, ihre herstellung und verwendung als medikamenten - Google Patents
Amidin-derivate, ihre herstellung und verwendung als medikamentenInfo
- Publication number
- DE60026161D1 DE60026161D1 DE60026161T DE60026161T DE60026161D1 DE 60026161 D1 DE60026161 D1 DE 60026161D1 DE 60026161 T DE60026161 T DE 60026161T DE 60026161 T DE60026161 T DE 60026161T DE 60026161 D1 DE60026161 D1 DE 60026161D1
- Authority
- DE
- Germany
- Prior art keywords
- medicaments
- preparation
- sup
- sub
- amidine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 150000001409 amidines Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 102000008299 Nitric Oxide Synthase Human genes 0.000 abstract 1
- 108010021487 Nitric Oxide Synthase Proteins 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000005282 allenyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004966 cyanoalkyl group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9914334 | 1999-11-16 | ||
| FR9914334A FR2801053B1 (fr) | 1999-11-16 | 1999-11-16 | Nouveaux derives d'amidines, leur preparation et leur application a titre de medicaments |
| PCT/FR2000/003168 WO2001036407A1 (fr) | 1999-11-16 | 2000-11-15 | Nouveaux derives d'amidines, leur preparation et leur application a titre de medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60026161D1 true DE60026161D1 (de) | 2006-04-27 |
| DE60026161T2 DE60026161T2 (de) | 2006-11-16 |
Family
ID=9552131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60026161T Expired - Fee Related DE60026161T2 (de) | 1999-11-16 | 2000-11-15 | Amidin-derivate, ihre herstellung und verwendung als medikamente |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US6770669B1 (de) |
| EP (1) | EP1233957B1 (de) |
| JP (1) | JP2003514811A (de) |
| AT (1) | ATE318265T1 (de) |
| AU (1) | AU1712601A (de) |
| CA (1) | CA2391598A1 (de) |
| CZ (1) | CZ20021645A3 (de) |
| DE (1) | DE60026161T2 (de) |
| ES (1) | ES2258984T3 (de) |
| FR (1) | FR2801053B1 (de) |
| HU (1) | HUP0203557A3 (de) |
| PL (1) | PL355677A1 (de) |
| RU (1) | RU2272807C2 (de) |
| WO (1) | WO2001036407A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2801053B1 (fr) * | 1999-11-16 | 2004-06-25 | Sod Conseils Rech Applic | Nouveaux derives d'amidines, leur preparation et leur application a titre de medicaments |
| RU2260005C2 (ru) | 2000-03-16 | 2005-09-10 | Сосьете Де Консей Де Решерш Э Д'Аппликасьон Сьентифик (С.К.Р.А.С.) | Производные липоевой кислоты, способ их получения (варианты) и фармацевтическая композиция |
| DE10162114A1 (de) * | 2001-12-12 | 2003-06-26 | Schering Ag | Neue Amidin-Derivate und deren Verwendung in Arzneimitteln |
| WO2008058167A2 (en) * | 2006-11-07 | 2008-05-15 | Case Western Reserve University | Method for treating disorders associated with complement activation |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA43318C2 (uk) * | 1992-02-05 | 2001-12-17 | Берінгер Інгельхейм Кг | Похідні амідину, фармацевтична композиція з антагоністичною по відношенню до лейкотриєну в4 активністю |
| IL110643A (en) * | 1993-08-12 | 1998-07-15 | Astra Ab | Amidine derivatives their preparation and pharmaceutical compositions containing them |
| AU2629795A (en) * | 1994-12-12 | 1996-07-03 | Chugai Seiyaku Kabushiki Kaisha | Aniline derivative having the effect of inhibiting nitrogen monoxide synthase |
| AU2978197A (en) * | 1996-06-04 | 1998-01-05 | Chugai Seiyaku Kabushiki Kaisha | Substituted benzenes having nos inhibitory effects |
| AUPO252896A0 (en) * | 1996-09-24 | 1996-10-17 | Fujisawa Pharmaceutical Co., Ltd. | Amidine derivatives |
| US6335445B1 (en) * | 1997-03-24 | 2002-01-01 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them |
| FR2764889B1 (fr) * | 1997-06-20 | 2000-09-01 | Sod Conseils Rech Applic | Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
| FR2761066B1 (fr) * | 1997-03-24 | 2000-11-24 | Sod Conseils Rech Applic | Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
| FR2783519B1 (fr) * | 1998-09-23 | 2003-01-24 | Sod Conseils Rech Applic | Nouveaux derives d'amidines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
| FR2801053B1 (fr) * | 1999-11-16 | 2004-06-25 | Sod Conseils Rech Applic | Nouveaux derives d'amidines, leur preparation et leur application a titre de medicaments |
| US6706754B2 (en) * | 2000-11-06 | 2004-03-16 | The United States Of America As Represented By The Secretary Of The Army | Reversed amidines and methods of using for treating, preventing, or inhibiting leishmaniasis |
-
1999
- 1999-11-16 FR FR9914334A patent/FR2801053B1/fr not_active Expired - Fee Related
-
2000
- 2000-11-15 JP JP2001538896A patent/JP2003514811A/ja active Pending
- 2000-11-15 US US10/111,434 patent/US6770669B1/en not_active Expired - Fee Related
- 2000-11-15 PL PL00355677A patent/PL355677A1/xx not_active Application Discontinuation
- 2000-11-15 RU RU2002115868/04A patent/RU2272807C2/ru not_active IP Right Cessation
- 2000-11-15 CA CA002391598A patent/CA2391598A1/fr not_active Abandoned
- 2000-11-15 EP EP00979732A patent/EP1233957B1/de not_active Expired - Lifetime
- 2000-11-15 WO PCT/FR2000/003168 patent/WO2001036407A1/fr not_active Ceased
- 2000-11-15 ES ES00979732T patent/ES2258984T3/es not_active Expired - Lifetime
- 2000-11-15 CZ CZ20021645A patent/CZ20021645A3/cs unknown
- 2000-11-15 HU HU0203557A patent/HUP0203557A3/hu unknown
- 2000-11-15 AU AU17126/01A patent/AU1712601A/en not_active Abandoned
- 2000-11-15 DE DE60026161T patent/DE60026161T2/de not_active Expired - Fee Related
- 2000-11-15 AT AT00979732T patent/ATE318265T1/de not_active IP Right Cessation
-
2004
- 2004-04-29 US US10/834,654 patent/US7019025B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1233957A1 (de) | 2002-08-28 |
| HUP0203557A2 (hu) | 2003-03-28 |
| HUP0203557A3 (en) | 2005-02-28 |
| US7019025B2 (en) | 2006-03-28 |
| US6770669B1 (en) | 2004-08-03 |
| ATE318265T1 (de) | 2006-03-15 |
| CA2391598A1 (fr) | 2001-05-25 |
| RU2272807C2 (ru) | 2006-03-27 |
| RU2002115868A (ru) | 2004-01-20 |
| US20040225008A1 (en) | 2004-11-11 |
| DE60026161T2 (de) | 2006-11-16 |
| WO2001036407A1 (fr) | 2001-05-25 |
| EP1233957B1 (de) | 2006-02-22 |
| JP2003514811A (ja) | 2003-04-22 |
| AU1712601A (en) | 2001-05-30 |
| CZ20021645A3 (cs) | 2002-09-11 |
| FR2801053A1 (fr) | 2001-05-18 |
| FR2801053B1 (fr) | 2004-06-25 |
| ES2258984T3 (es) | 2006-09-16 |
| PL355677A1 (en) | 2004-05-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |