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DE60026404D1 - Verfahren zur Herstellung von Benzothiophen-Derivaten - Google Patents

Verfahren zur Herstellung von Benzothiophen-Derivaten

Info

Publication number
DE60026404D1
DE60026404D1 DE60026404T DE60026404T DE60026404D1 DE 60026404 D1 DE60026404 D1 DE 60026404D1 DE 60026404 T DE60026404 T DE 60026404T DE 60026404 T DE60026404 T DE 60026404T DE 60026404 D1 DE60026404 D1 DE 60026404D1
Authority
DE
Germany
Prior art keywords
preparation
formula
benzothiophene derivatives
chem
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60026404T
Other languages
English (en)
Other versions
DE60026404T2 (de
Inventor
Bernd Junghans
Michelangelo Scalone
Thomas Albert Zeibig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE60026404D1 publication Critical patent/DE60026404D1/de
Application granted granted Critical
Publication of DE60026404T2 publication Critical patent/DE60026404T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60026404T 1999-08-02 2000-07-25 Verfahren zur Herstellung von Benzothiophen-Derivaten Expired - Fee Related DE60026404T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99115222 1999-08-02
EP99115222 1999-08-02

Publications (2)

Publication Number Publication Date
DE60026404D1 true DE60026404D1 (de) 2006-05-04
DE60026404T2 DE60026404T2 (de) 2006-10-19

Family

ID=8238708

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60026404T Expired - Fee Related DE60026404T2 (de) 1999-08-02 2000-07-25 Verfahren zur Herstellung von Benzothiophen-Derivaten

Country Status (13)

Country Link
US (3) US6291685B1 (de)
EP (1) EP1078923B1 (de)
JP (2) JP3278649B2 (de)
KR (1) KR100440102B1 (de)
CN (1) CN1123570C (de)
AT (1) ATE319702T1 (de)
CA (1) CA2314699A1 (de)
CY (1) CY1106096T1 (de)
DE (1) DE60026404T2 (de)
DK (1) DK1078923T3 (de)
ES (1) ES2258431T3 (de)
JO (1) JO2239B1 (de)
PT (1) PT1078923E (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6531609B2 (en) 2000-04-14 2003-03-11 Hoffmann-La Roche Inc. Process for the preparation of thiazolidinedione derivatives
AU2002230409A1 (en) * 2000-11-27 2002-06-03 Eli Lilly And Company Process for preparing 3-aryl-benzo(b)thiophenes
JP4056883B2 (ja) 2001-01-25 2008-03-05 エフ．ホフマン−ラ ロシュ アーゲー ヘテロ環式インデン類似体の調製方法
DE60206363T2 (de) 2001-02-12 2006-07-06 F. Hoffmann-La Roche Ag 6-substituierte pyridopyrimidine
EP1362854B1 (de) * 2001-02-22 2007-10-31 Teijin Pharma Limited Benzo[b[thiophenderivate und Verfahren zu deren Herstellung
SE0100903D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0100902D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
MXPA03010435A (es) 2001-05-15 2004-03-09 Hoffmann La Roche Derivados de oxazol acido carboxilico sustituidos para uso como activadores de proliferacion del peroximosa(ppar-alfa y gama) en el tratamiento de diabetes.
DE60316290T2 (de) 2002-07-03 2008-06-12 F. Hoffmann-La Roche Ag Oxazolderivate und deren verwendung als insulinsensibilisatoren
SE0202539D0 (sv) * 2002-08-27 2002-08-27 Astrazeneca Ab Compounds
ES2350340T3 (es) 2002-08-30 2011-01-21 F. Hoffmann-La Roche Ag Nuevos compuestos de 2-aril-tiazol como agonistas de pparalfa y ppargamma.
PL375878A1 (en) 2002-09-12 2005-12-12 F.Hoffmann-La Roche Ag N-substituted-1h-indol-5-propionic acid compounds as ppar agonists useful for the treatment of diabetes
BR0316556A (pt) 2002-11-25 2005-10-04 Hoffmann La Roche Compostos, processo para a preparação de um composto, composição farmacêutica que compreende esse composto, sua utilização e método para o tratamento e/ou profilaxia de enfermidades que são moduladas por agonistas ppar(alfa) e/ou ppary
GB0311091D0 (en) * 2003-05-14 2003-06-18 Bp Chem Int Ltd Process
GB0311092D0 (en) * 2003-05-14 2003-06-18 Bp Chem Int Ltd Process
SE0401762D0 (sv) * 2004-07-05 2004-07-05 Astrazeneca Ab Novel compounds
US7648992B2 (en) 2004-07-05 2010-01-19 Astrazeneca Ab Hydantoin derivatives for the treatment of obstructive airway diseases
SE0401763D0 (sv) * 2004-07-05 2004-07-05 Astrazeneca Ab Compounds
SE0403086D0 (sv) 2004-12-17 2004-12-17 Astrazeneca Ab Compounds
SE0403085D0 (sv) * 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
DE102005017216A1 (de) * 2005-04-14 2006-10-19 Deutsches Zentrum für Luft- und Raumfahrttechnik e.V. Thermische Wasserstoffherstellung in einer Gas-Festphasenreaktion
TW200831488A (en) * 2006-11-29 2008-08-01 Astrazeneca Ab Novel compounds
EP3479334A4 (de) 2016-06-30 2020-03-04 Cutaneous Information Technologies, LLC System und verfahren für pflegeübergänge
CN115805103B (zh) * 2021-09-14 2024-04-09 万华化学集团股份有限公司 一种失活钛硅分子筛的再生方法
CN116459873B (zh) * 2022-01-12 2025-02-18 万华化学集团股份有限公司 一种烯属不饱和化合物羰基化催化剂及其制备方法、应用
CN117019118B (zh) * 2023-10-08 2024-01-05 西安金沃泰环保科技有限公司 一种用于苯系废气的过滤材料及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5330998A (en) * 1988-03-08 1994-07-19 Pfizer Inc. Thiazolidinedione derivatives as hypoglycemic agents
CA2008878C (en) 1989-02-28 2003-01-21 Michelangelo Scalone Process for preparing pyridine-2-carboxamides
DE4317320A1 (de) * 1993-05-25 1994-12-01 Boehringer Mannheim Gmbh Neue Thiazolidindione und diese enthaltende Arzneimittel
AU2791897A (en) * 1996-06-26 1998-01-14 Chugai Seiyaku Kabushiki Kaisha Remedies for renal diseases and organ-preserving agents
CA2259487A1 (en) * 1996-07-01 1998-01-08 Margaret Mary Faul Hypoglycemic and hypolipidemic compounds
DE19711616A1 (de) 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen

Also Published As

Publication number Publication date
JP2002155079A (ja) 2002-05-28
DE60026404T2 (de) 2006-10-19
PT1078923E (pt) 2006-07-31
EP1078923A3 (de) 2001-07-11
DK1078923T3 (da) 2006-07-10
US6291685B1 (en) 2001-09-18
KR100440102B1 (ko) 2004-07-15
US20020010345A1 (en) 2002-01-24
EP1078923B1 (de) 2006-03-08
US6482958B2 (en) 2002-11-19
EP1078923A2 (de) 2001-02-28
JP2001048876A (ja) 2001-02-20
US6437144B2 (en) 2002-08-20
CN1282741A (zh) 2001-02-07
CY1106096T1 (el) 2011-06-08
CA2314699A1 (en) 2001-02-02
US20020077488A1 (en) 2002-06-20
CN1123570C (zh) 2003-10-08
ES2258431T3 (es) 2006-09-01
KR20010049948A (ko) 2001-06-15
JP3278649B2 (ja) 2002-04-30
JO2239B1 (en) 2004-10-07
ATE319702T1 (de) 2006-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee