DE60013434D1 - Verfahren zur trennung analoger organischer verbindungen - Google Patents

Verfahren zur trennung analoger organischer verbindungen

Info

Publication number: DE60013434D1
Authority: DE; Germany
Prior art keywords: organic compounds; separating analog; analog organic; separating; compounds
Prior art date: 1999-05-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60013434T

Other languages

English (en)

Other versions

DE60013434T2 (de

Inventor

Yutaka Nishihara

Keiji Honda

Koji Mukai

Norihiro Hashimoto

Hiroshi Hatanaka

Michio Yamashita

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Astellas Pharma Inc

Original Assignee

Fujisawa Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-25

Filing date

2000-05-19

Publication date

2004-10-07

2000-05-19 Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd

2004-10-07 Publication of DE60013434D1 publication Critical patent/DE60013434D1/de

2005-01-20 Application granted granted Critical

2005-01-20 Publication of DE60013434T2 publication Critical patent/DE60013434T2/de

2020-05-20 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1814—Recycling of the fraction to be distributed
- B01D15/1821—Simulated moving beds
- B01D15/185—Simulated moving beds characterised by the components to be separated
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/04—Processes using organic exchangers
- B01J39/05—Processes using organic exchangers in the strongly acidic form
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/16—Organic material
- B01J39/18—Macromolecular compounds
- B01J39/20—Macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/26—Cation exchangers for chromatographic processes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1814—Recycling of the fraction to be distributed
- B01D15/1821—Simulated moving beds

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Analytical Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Sustainable Development (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Manufacture Of Macromolecular Shaped Articles (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

DE60013434T 1999-05-25 2000-05-19 Verfahren zur trennung analoger organischer verbindungen Expired - Lifetime DE60013434T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP14510399		1999-05-25
JP14510399		1999-05-25
PCT/JP2000/003251 WO2000071546A1 (en)	1999-05-25	2000-05-19	Method for separating analogous organic compounds

Publications (2)

Publication Number	Publication Date
DE60013434D1 true DE60013434D1 (de)	2004-10-07
DE60013434T2 DE60013434T2 (de)	2005-01-20

Family

ID=15377455

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60013434T Expired - Lifetime DE60013434T2 (de)	1999-05-25	2000-05-19	Verfahren zur trennung analoger organischer verbindungen

Country Status (26)

Country	Link
US (1)	US6492513B1 (de)
EP (1)	EP1183261B1 (de)
JP (1)	JP3750527B2 (de)
KR (1)	KR100443048B1 (de)
CN (1)	CN1154651C (de)
AR (1)	AR024068A1 (de)
AT (1)	ATE275150T1 (de)
AU (1)	AU775075C (de)
BR (1)	BR0011597B1 (de)
CA (1)	CA2374999C (de)
CZ (1)	CZ300783B6 (de)
DE (1)	DE60013434T2 (de)
DK (1)	DK1183261T3 (de)
ES (1)	ES2223514T3 (de)
HU (1)	HU228268B1 (de)
IL (2)	IL146285A0 (de)
MX (1)	MXPA01011566A (de)
NO (1)	NO321407B1 (de)
NZ (1)	NZ515462A (de)
PL (1)	PL199512B1 (de)
PT (1)	PT1183261E (de)
RU (1)	RU2234509C2 (de)
TR (1)	TR200103360T2 (de)
TW (1)	TW500725B (de)
WO (1)	WO2000071546A1 (de)
ZA (1)	ZA200109093B (de)

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US7452692B2 (en)	2002-02-13	2008-11-18	Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság	Method for extracting a macrolide from biomatter
JP4261365B2 (ja)	2002-02-13	2009-04-30	テバジョジセルジャールザ−トケルエンムケドレ−スベニュタ−ルシャシャ−グ	生物学的物質からのマクロライドの抽出方法
US7645876B2 (en) *	2004-12-01	2010-01-12	TEVA Gyógyszergyár Zártkörúen Müködö Részvénytársaság	Processes for producing crystalline macrolides
SI1697383T1 (sl) *	2003-12-05	2014-09-30	Biocon Limited	Postopek za ÄŤiĹˇÄŤenje takrolimusa
WO2005098011A1 (en) *	2004-04-12	2005-10-20	Biocon Limited	Process for the production of macrolides using a novel strain, streptomyces sp. bicc 7522
US20080312447A1 (en) *	2004-09-10	2008-12-18	Ivax Pharmaceuticals S.R.O.	Process for Isolation of Crystalline Tacrolimus
CN101031654A (zh) *	2004-09-10	2007-09-05	伊瓦克斯制药有限公司	结晶他克莫司的分离方法
ITMI20042098A1 (it) *	2004-11-03	2005-02-03	Antibioticos Spa	Processo per la purificazione di tacrolimus
TW200637834A (en) *	2004-12-22	2006-11-01	Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag	Method of purifying macrolides
MX2007006119A (es) *	2005-01-05	2007-07-19	Teva Gyogyszergyar Zartkoruen	Tacrolimus amorfo y preparacion de el.
WO2007013017A1 (en) *	2005-07-29	2007-02-01	Ranbaxy Laboratories Limited	A process for purification of macrolides
ITMI20051549A1 (it) *	2005-08-05	2007-02-06	Antibioticos Spa	Purificazione del tacrolimus su supporti dimorigine vegetale
WO2007075499A2 (en) *	2005-12-16	2007-07-05	Archer-Daniels-Midland Company	Method of preparing a composition using argentation chromatography
EP1896488B1 (de) *	2006-03-15	2010-05-19	TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság	Verfahren zur reinigung von tacrolimus
TW200815458A (en) *	2006-03-15	2008-04-01	Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag	Process for purifying Tacrolimus
KR100859670B1 (ko) *	2006-09-13	2008-09-23	동국제약 주식회사	타크로리무스를 고수율 및 고순도로 정제하는 방법
KR20090094090A (ko) *	2006-12-28	2009-09-03	리머릭 바이오파르마 인코오포레이티드	치료를 위한 방법 및 조성물
MX2010001141A (es) *	2007-07-31	2010-03-01	Limerick Biopharma Inc	Analogos fosforiladosde pirona y metodos.
KR101003042B1 (ko)	2008-03-17	2010-12-21	종근당바이오 주식회사	고순도 타크로리무스의 정제 방법
KR100910165B1 (ko)	2008-09-18	2009-07-30	(주) 제노텍	은 이온 용액 추출을 이용한 불포화 알킬기를 가진 락톤 화합물 정제방법
US20110318277A1 (en)	2010-06-25	2011-12-29	APT Pharmaceuticals, Inc. University of Maryland, Baltimore	Tacrolimus compositions for aerosol administration
TWI428167B (zh) *	2011-12-29	2014-03-01	Univ Ishou	一種以模擬移動床分離不同分子量高分子之方法
US8470755B1 (en)	2012-03-23	2013-06-25	The Procter & Gamble Company	Liquid cleaning and disinfecting compositions comprising a zinc inorganic salt
US9133417B2 (en)	2012-03-23	2015-09-15	The Procter & Gamble Company	Liquid cleaning and disinfecting compositions comprising an assymetrically branched amine oxide
CN104428308B (zh) *	2012-07-06	2016-11-09	合同酒精株式会社	环状大环内酯类化合物的分离方法
CN106083892B (zh) *	2016-06-13	2019-02-19	杭州中美华东制药有限公司	他克莫司化合物及其制备方法
RU2694354C1 (ru) *	2018-09-25	2019-07-11	Закрытое акционерное общество "БиоХимМак СТ"	Способ сорбционно-хроматографического выделения и очистки такролимуса
CN111909176B (zh) *	2020-08-14	2022-03-15	卓和药业集团股份有限公司	一种从他克莫司分离废液中回收子囊霉素、他克莫司8-丙基类似物的方法

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JPS4988801A (de) *	1972-12-29	1974-08-24
US4826603A (en)	1986-09-09	1989-05-02	United States Of America As Represented By The Secretary Of The Air Force	Hydrocarbon group-type analyzer system
JPH06185397A (ja) *	1992-12-15	1994-07-05	Mazda Motor Corp	燃料噴射式エンジンの燃料噴射量制御装置
KR970002037B1 (ko)	1994-12-09	1997-02-21	농촌진흥청	들깨유로부터 α-리놀렌산(ALA)을 분리, 정제하는 방법
US5616595A (en) *	1995-06-07	1997-04-01	Abbott Laboratories	Process for recovering water insoluble compounds from a fermentation broth
KR100244164B1 (ko) *	1997-07-15	2000-03-02	김용옥	수용성 고분자-타크로리무스 접합체 화합물 및 그의 제조 방법

2000
- 2000-05-19 DK DK00927830T patent/DK1183261T3/da active
- 2000-05-19 AU AU46154/00A patent/AU775075C/en not_active Expired
- 2000-05-19 JP JP2000619802A patent/JP3750527B2/ja not_active Expired - Lifetime
- 2000-05-19 PL PL357015A patent/PL199512B1/pl unknown
- 2000-05-19 US US09/926,611 patent/US6492513B1/en not_active Expired - Lifetime
- 2000-05-19 NZ NZ515462A patent/NZ515462A/en not_active IP Right Cessation
- 2000-05-19 TR TR2001/03360T patent/TR200103360T2/xx unknown
- 2000-05-19 RU RU2001134894/15A patent/RU2234509C2/ru active
- 2000-05-19 CZ CZ20014209A patent/CZ300783B6/cs not_active IP Right Cessation
- 2000-05-19 CN CNB008079757A patent/CN1154651C/zh not_active Expired - Lifetime
- 2000-05-19 PT PT00927830T patent/PT1183261E/pt unknown
- 2000-05-19 IL IL14628500A patent/IL146285A0/xx unknown
- 2000-05-19 BR BRPI0011597-5A patent/BR0011597B1/pt not_active IP Right Cessation
- 2000-05-19 WO PCT/JP2000/003251 patent/WO2000071546A1/en not_active Ceased
- 2000-05-19 ES ES00927830T patent/ES2223514T3/es not_active Expired - Lifetime
- 2000-05-19 AT AT00927830T patent/ATE275150T1/de active
- 2000-05-19 DE DE60013434T patent/DE60013434T2/de not_active Expired - Lifetime
- 2000-05-19 HU HU0201481A patent/HU228268B1/hu unknown
- 2000-05-19 EP EP00927830A patent/EP1183261B1/de not_active Expired - Lifetime
- 2000-05-19 MX MXPA01011566A patent/MXPA01011566A/es active IP Right Grant
- 2000-05-19 CA CA002374999A patent/CA2374999C/en not_active Expired - Lifetime
- 2000-05-19 KR KR10-2001-7013989A patent/KR100443048B1/ko not_active Expired - Lifetime
- 2000-05-23 AR ARP000102504A patent/AR024068A1/es active IP Right Grant
- 2000-05-24 TW TW089110055A patent/TW500725B/zh not_active IP Right Cessation
2001
- 2001-11-01 IL IL146285A patent/IL146285A/en not_active IP Right Cessation
- 2001-11-02 ZA ZA200109093A patent/ZA200109093B/xx unknown
- 2001-11-15 NO NO20015579A patent/NO321407B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2223514T3 (es)	2005-03-01
NO20015579D0 (no)	2001-11-15
RU2234509C2 (ru)	2004-08-20
HK1050528A1 (en)	2003-06-27
EP1183261A1 (de)	2002-03-06
CA2374999A1 (en)	2000-11-30
JP3750527B2 (ja)	2006-03-01
MXPA01011566A (es)	2002-06-04
CA2374999C (en)	2009-03-10
AU4615400A (en)	2000-12-12
CN1154651C (zh)	2004-06-23
KR20020032423A (ko)	2002-05-03
US6492513B1 (en)	2002-12-10
BR0011597A (pt)	2002-03-05
NO20015579L (no)	2002-01-17
KR100443048B1 (ko)	2004-08-04
WO2000071546A1 (en)	2000-11-30
HUP0201481A2 (en)	2002-08-28
NO321407B1 (no)	2006-05-08
CN1378548A (zh)	2002-11-06
ZA200109093B (en)	2003-09-23
DK1183261T3 (da)	2005-01-17
JP2004505749A (ja)	2004-02-26
CZ20014209A3 (cs)	2002-04-17
PL199512B1 (pl)	2008-09-30
ATE275150T1 (de)	2004-09-15
AU775075C (en)	2005-02-24
NZ515462A (en)	2004-05-28
AR024068A1 (es)	2002-09-04
TR200103360T2 (tr)	2002-10-21
BR0011597B1 (pt)	2011-03-22
IL146285A0 (en)	2002-07-25
IL146285A (en)	2009-11-18
CZ300783B6 (cs)	2009-08-12
AU775075B2 (en)	2004-07-15
TW500725B (en)	2002-09-01
DE60013434T2 (de)	2005-01-20
PL357015A1 (en)	2004-07-12
PT1183261E (pt)	2004-11-30
HU228268B1 (en)	2013-02-28
EP1183261B1 (de)	2004-09-01

Publication	Publication Date	Title
DE60013434D1 (de)	2004-10-07	Verfahren zur trennung analoger organischer verbindungen
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DE60041503D1 (de)	2009-03-19	Verfahren zur konturkorrektur
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DE60024535D1 (de)	2006-01-12	Verfahren zur Zeichentrennung
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DE60104535D1 (de)	2004-09-02	Verfahren zur hydroxylation von aliphatischen verbindungen
DE60010753D1 (de)	2004-06-17	Verfahren zur reinigung von lactamen
DE60020816D1 (de)	2005-07-21	Verbindungen und verfahren zur änderung der genexpression
DE50101464D1 (de)	2004-03-18	Verfahren zur elektrochemischen Reduktion organischer Verbindungen.
DE50010031D1 (de)	2005-05-19	Verfahren zur Antriebsschlupfregelung
DE60328693D1 (de)	2009-09-17	Verfahren zur oxadimierung von carbonylverbindungen
DE60004651D1 (de)	2003-09-25	Verfahren zur selektiven fluorierung von organischen verbindungen

Legal Events

Date	Code	Title	Description
2005-09-29	8364	No opposition during term of opposition
2006-04-27	8327	Change in the person/name/address of the patent owner	Owner name: ASTELLAS PHARMA INC., TOKIO/TOKYO, JP