DE60012183D1 - Verwendung einer makrolid-verbindung zur herstellung eines medikaments zur behandlung von gehirnschäden aufgrund von ischämie oder blutungen - Google Patents
Verwendung einer makrolid-verbindung zur herstellung eines medikaments zur behandlung von gehirnschäden aufgrund von ischämie oder blutungenInfo
- Publication number
- DE60012183D1 DE60012183D1 DE60012183T DE60012183T DE60012183D1 DE 60012183 D1 DE60012183 D1 DE 60012183D1 DE 60012183 T DE60012183 T DE 60012183T DE 60012183 T DE60012183 T DE 60012183T DE 60012183 D1 DE60012183 D1 DE 60012183D1
- Authority
- DE
- Germany
- Prior art keywords
- ischemia
- bleeding
- medicine
- producing
- damage due
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000003120 macrolide antibiotic agent Substances 0.000 title abstract 2
- 230000000740 bleeding effect Effects 0.000 title 1
- 230000006931 brain damage Effects 0.000 title 1
- 231100000874 brain damage Toxicity 0.000 title 1
- 208000029028 brain injury Diseases 0.000 title 1
- 208000028867 ischemia Diseases 0.000 title 1
- QJJXYPPXXYFBGM-LFZNUXCKSA-N Tacrolimus Chemical class C1C[C@@H](O)[C@H](OC)C[C@@H]1\C=C(/C)[C@@H]1[C@H](C)[C@@H](O)CC(=O)[C@H](CC=C)/C=C(C)/C[C@H](C)C[C@H](OC)[C@H]([C@H](C[C@H]2C)OC)O[C@@]2(O)C(=O)C(=O)N2CCCC[C@H]2C(=O)O1 QJJXYPPXXYFBGM-LFZNUXCKSA-N 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 239000004090 neuroprotective agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9917158.9A GB9917158D0 (en) | 1999-07-21 | 1999-07-21 | New use |
| GB9917158 | 1999-07-21 | ||
| PCT/GB2000/002788 WO2001005385A2 (en) | 1999-07-21 | 2000-07-19 | New use of a macrolide compound for treating neurodegenerative disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60012183D1 true DE60012183D1 (de) | 2004-08-19 |
| DE60012183T2 DE60012183T2 (de) | 2004-11-18 |
Family
ID=10857695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2000612183 Expired - Fee Related DE60012183T2 (de) | 1999-07-21 | 2000-07-19 | Verwendung einer makrolid-verbindung zur herstellung eines medikaments zur behandlung von gehirnschäden aufgrund von ischämie oder blutungen |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20060287353A1 (de) |
| EP (1) | EP1196170B1 (de) |
| JP (1) | JP2003504396A (de) |
| KR (1) | KR100508623B1 (de) |
| CN (1) | CN1200710C (de) |
| AT (1) | ATE270888T1 (de) |
| AU (1) | AU6003900A (de) |
| CA (1) | CA2379140A1 (de) |
| DE (1) | DE60012183T2 (de) |
| DK (1) | DK1196170T3 (de) |
| ES (1) | ES2220492T3 (de) |
| GB (1) | GB9917158D0 (de) |
| HK (1) | HK1047704B (de) |
| PT (1) | PT1196170E (de) |
| WO (1) | WO2001005385A2 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR035411A1 (es) * | 2000-12-29 | 2004-05-26 | Fujisawa Pharmaceutical Co | Uso de un derivado de tacrolimus para fabricar un agente neurotrofico, composiciones y articulos de fabricacion o kits que lo comprenden, metodo para fabricar un agente que lo comprende y tejidos e injertos con una celula nerviosa tratada con este compuesto |
| AU2003901023A0 (en) * | 2003-03-04 | 2003-03-20 | Fujisawa Pharmaceutical Co., Ltd. | New use |
| KR20060125849A (ko) * | 2004-01-20 | 2006-12-06 | 아스텔라스세이야쿠 가부시키가이샤 | 발기부전 치료 방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4894366A (en) * | 1984-12-03 | 1990-01-16 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
| GB8728820D0 (en) * | 1987-12-09 | 1988-01-27 | Fisons Plc | Compounds |
| GR1001225B (el) * | 1989-09-14 | 1993-06-30 | Fisons Plc | Νέαι μακροκυκλικαί ενώσεις και νέα μέ?οδος χρήσεως τους. |
| GB9202196D0 (en) * | 1992-02-01 | 1992-03-18 | Fisons Plc | Method of treatment |
| GB9218027D0 (en) * | 1992-08-25 | 1992-10-14 | Fisons Plc | Novel method of treatment |
| GB9227055D0 (en) * | 1992-12-29 | 1993-02-24 | Fujisawa Pharmaceutical Co | New use |
-
1999
- 1999-07-21 GB GBGB9917158.9A patent/GB9917158D0/en not_active Ceased
-
2000
- 2000-07-19 EP EP00946165A patent/EP1196170B1/de not_active Expired - Lifetime
- 2000-07-19 CA CA002379140A patent/CA2379140A1/en not_active Abandoned
- 2000-07-19 WO PCT/GB2000/002788 patent/WO2001005385A2/en not_active Ceased
- 2000-07-19 AT AT00946165T patent/ATE270888T1/de not_active IP Right Cessation
- 2000-07-19 AU AU60039/00A patent/AU6003900A/en not_active Abandoned
- 2000-07-19 CN CNB008105898A patent/CN1200710C/zh not_active Expired - Fee Related
- 2000-07-19 ES ES00946165T patent/ES2220492T3/es not_active Expired - Lifetime
- 2000-07-19 PT PT00946165T patent/PT1196170E/pt unknown
- 2000-07-19 KR KR10-2002-7000291A patent/KR100508623B1/ko not_active Expired - Fee Related
- 2000-07-19 HK HK02109332.6A patent/HK1047704B/zh not_active IP Right Cessation
- 2000-07-19 DK DK00946165T patent/DK1196170T3/da active
- 2000-07-19 JP JP2001510442A patent/JP2003504396A/ja not_active Withdrawn
- 2000-07-19 DE DE2000612183 patent/DE60012183T2/de not_active Expired - Fee Related
-
2006
- 2006-04-18 US US11/405,679 patent/US20060287353A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003504396A (ja) | 2003-02-04 |
| KR20020060148A (ko) | 2002-07-16 |
| PT1196170E (pt) | 2004-10-29 |
| CN1361691A (zh) | 2002-07-31 |
| WO2001005385A2 (en) | 2001-01-25 |
| DK1196170T3 (da) | 2004-08-30 |
| HK1047704B (zh) | 2005-12-16 |
| ATE270888T1 (de) | 2004-07-15 |
| EP1196170A2 (de) | 2002-04-17 |
| US20060287353A1 (en) | 2006-12-21 |
| DE60012183T2 (de) | 2004-11-18 |
| CA2379140A1 (en) | 2001-01-25 |
| CN1200710C (zh) | 2005-05-11 |
| GB9917158D0 (en) | 1999-09-22 |
| WO2001005385A3 (en) | 2001-08-02 |
| ES2220492T3 (es) | 2004-12-16 |
| EP1196170B1 (de) | 2004-07-14 |
| AU6003900A (en) | 2001-02-05 |
| KR100508623B1 (ko) | 2005-08-17 |
| HK1047704A1 (en) | 2003-03-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: ASTELLAS PHARMA INC., TOKIO/TOKYO, JP |
|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |