DE4419783A1 - Medicated shampoo for hair care and treatment - Google Patents
Medicated shampoo for hair care and treatmentInfo
- Publication number
- DE4419783A1 DE4419783A1 DE4419783A DE4419783A DE4419783A1 DE 4419783 A1 DE4419783 A1 DE 4419783A1 DE 4419783 A DE4419783 A DE 4419783A DE 4419783 A DE4419783 A DE 4419783A DE 4419783 A1 DE4419783 A1 DE 4419783A1
- Authority
- DE
- Germany
- Prior art keywords
- acid
- extract
- hair
- ascorbate
- texapon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 210000004209 hair Anatomy 0.000 title claims abstract description 16
- 229940103903 medicated shampoo Drugs 0.000 title 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 18
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229960002663 thioctic acid Drugs 0.000 claims abstract description 12
- 235000019136 lipoic acid Nutrition 0.000 claims abstract description 11
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 10
- 235000010323 ascorbic acid Nutrition 0.000 claims abstract description 9
- 239000011668 ascorbic acid Substances 0.000 claims abstract description 9
- 239000002453 shampoo Substances 0.000 claims abstract description 9
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 8
- 229930195729 fatty acid Natural products 0.000 claims abstract description 8
- 239000000194 fatty acid Substances 0.000 claims abstract description 8
- 150000004665 fatty acids Chemical class 0.000 claims abstract description 8
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000007859 condensation product Substances 0.000 claims abstract description 6
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 5
- IGEATPHOIPFRCJ-UHFFFAOYSA-N butane-2-sulfonic acid dithiolane Chemical compound CCC(C)S(=O)(=O)O.S1SCCC1 IGEATPHOIPFRCJ-UHFFFAOYSA-N 0.000 claims abstract description 5
- 150000002148 esters Chemical class 0.000 claims abstract description 5
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 5
- 229940046009 vitamin E Drugs 0.000 claims abstract description 5
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 5
- 239000011709 vitamin E Substances 0.000 claims abstract description 5
- 235000013405 beer Nutrition 0.000 claims abstract description 4
- 239000012141 concentrate Substances 0.000 claims abstract description 4
- FRPZMMHWLSIFAZ-UHFFFAOYSA-N 10-undecenoic acid Chemical compound OC(=O)CCCCCCCCC=C FRPZMMHWLSIFAZ-UHFFFAOYSA-N 0.000 claims abstract description 3
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 claims abstract description 3
- 239000005639 Lauric acid Substances 0.000 claims abstract description 3
- SUZRRICLUFMAQD-UHFFFAOYSA-N N-Methyltaurine Chemical compound CNCCS(O)(=O)=O SUZRRICLUFMAQD-UHFFFAOYSA-N 0.000 claims abstract description 3
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims abstract description 3
- KHAVLLBUVKBTBG-UHFFFAOYSA-N caproleic acid Natural products OC(=O)CCCCCCCC=C KHAVLLBUVKBTBG-UHFFFAOYSA-N 0.000 claims abstract description 3
- 239000003531 protein hydrolysate Substances 0.000 claims abstract description 3
- 125000003748 selenium group Chemical class *[Se]* 0.000 claims abstract description 3
- 159000000000 sodium salts Chemical class 0.000 claims abstract description 3
- 229960002703 undecylenic acid Drugs 0.000 claims abstract description 3
- 239000013543 active substance Substances 0.000 claims abstract 2
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical compound OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 claims description 10
- 239000002253 acid Substances 0.000 claims description 10
- 201000004384 Alopecia Diseases 0.000 claims description 7
- 208000008742 seborrheic dermatitis Diseases 0.000 claims description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 4
- 150000001447 alkali salts Chemical class 0.000 claims description 4
- 210000004761 scalp Anatomy 0.000 claims description 4
- 240000003538 Chamaemelum nobile Species 0.000 claims description 3
- 235000007866 Chamaemelum nobile Nutrition 0.000 claims description 3
- 208000001840 Dandruff Diseases 0.000 claims description 3
- 235000007232 Matricaria chamomilla Nutrition 0.000 claims description 3
- 206010039792 Seborrhoea Diseases 0.000 claims description 3
- 208000037824 growth disorder Diseases 0.000 claims description 3
- 230000003779 hair growth Effects 0.000 claims description 3
- 208000024963 hair loss Diseases 0.000 claims description 3
- 230000003676 hair loss Effects 0.000 claims description 3
- FKKAGFLIPSSCHT-UHFFFAOYSA-N 1-dodecoxydodecane;sulfuric acid Chemical compound OS(O)(=O)=O.CCCCCCCCCCCCOCCCCCCCCCCCC FKKAGFLIPSSCHT-UHFFFAOYSA-N 0.000 claims description 2
- 244000060011 Cocos nucifera Species 0.000 claims description 2
- 235000013162 Cocos nucifera Nutrition 0.000 claims description 2
- 201000004624 Dermatitis Diseases 0.000 claims description 2
- 208000006311 Pyoderma Diseases 0.000 claims description 2
- 206010039793 Seborrhoeic dermatitis Diseases 0.000 claims description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims description 2
- 231100000360 alopecia Toxicity 0.000 claims description 2
- 206010068168 androgenetic alopecia Diseases 0.000 claims description 2
- 201000002996 androgenic alopecia Diseases 0.000 claims description 2
- 208000010668 atopic eczema Diseases 0.000 claims description 2
- XVBRCOKDZVQYAY-UHFFFAOYSA-N bronidox Chemical compound [O-][N+](=O)C1(Br)COCOC1 XVBRCOKDZVQYAY-UHFFFAOYSA-N 0.000 claims description 2
- 239000000824 cytostatic agent Substances 0.000 claims description 2
- 230000001085 cytostatic effect Effects 0.000 claims description 2
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical compound [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 claims description 2
- QVBODZPPYSSMEL-UHFFFAOYSA-N dodecyl sulfate;2-hydroxyethylazanium Chemical compound NCCO.CCCCCCCCCCCCOS(O)(=O)=O QVBODZPPYSSMEL-UHFFFAOYSA-N 0.000 claims description 2
- 150000002191 fatty alcohols Chemical class 0.000 claims description 2
- 239000002304 perfume Substances 0.000 claims description 2
- 239000004033 plastic Substances 0.000 claims description 2
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims description 2
- 239000003755 preservative agent Substances 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- 239000011780 sodium chloride Substances 0.000 claims description 2
- 229960001471 sodium selenite Drugs 0.000 claims description 2
- 235000015921 sodium selenite Nutrition 0.000 claims description 2
- 239000011781 sodium selenite Substances 0.000 claims description 2
- 208000024891 symptom Diseases 0.000 claims description 2
- 229940072107 ascorbate Drugs 0.000 claims 7
- 235000019482 Palm oil Nutrition 0.000 claims 1
- 239000007844 bleaching agent Substances 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 235000019198 oils Nutrition 0.000 claims 1
- 239000002540 palm oil Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
- IZFHEQBZOYJLPK-SSDOTTSWSA-N (R)-dihydrolipoic acid Chemical compound OC(=O)CCCC[C@@H](S)CCS IZFHEQBZOYJLPK-SSDOTTSWSA-N 0.000 abstract description 3
- 229960005070 ascorbic acid Drugs 0.000 abstract description 2
- 108010009736 Protein Hydrolysates Proteins 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salts Chemical class 0.000 abstract 1
- SHMXLCRUTGTGGS-UHFFFAOYSA-N dithiolane-3-carboxylic acid Chemical compound OC(=O)C1CCSS1 SHMXLCRUTGTGGS-UHFFFAOYSA-N 0.000 abstract 1
- 239000003346 palm kernel oil Substances 0.000 abstract 1
- 235000019865 palm kernel oil Nutrition 0.000 abstract 1
- 159000000001 potassium salts Chemical class 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 4
- 230000003502 anti-nociceptive effect Effects 0.000 description 3
- 230000000202 analgesic effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000003780 hair follicle Anatomy 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 230000001925 catabolic effect Effects 0.000 description 1
- 208000037976 chronic inflammation Diseases 0.000 description 1
- 230000006020 chronic inflammation Effects 0.000 description 1
- 239000005515 coenzyme Substances 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 230000001120 cytoprotective effect Effects 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000000324 neuroprotective effect Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 239000002516 radical scavenger Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A shampoo (I) for treatment and care of hair contains at least the following active agents: (A) oxidised or reduced enantiomers of alpha -lipoic acid, dihydrolipoic acid (racemate) or their esters, 6,8-bis-nor-lipoic acid, tetra-nor-lipoic acid, or 1,2-dithiacyclopentane-3-butylsulphonic acid or their alkali metal salts, at a concn. of 0.2-10%; and (B) one or more combination partners such as selenium salts, disodium salts, potassium salts of a condensation product of lauric acid and protein hydrolysate, palm-kernel fatty acid sarcoside of methyltaurine, palm kernel oil fatty acid sarcoside of triethanolamine, sodium salt of a condensation product of undecylenic acid, water-soluble vitamin E or F, ascorbic acid, beer extract, camomile flower extract or dye concentrates.
Description
Die vorliegende Erfindung betrifft ein Haarkur-Pflege-Shampoo, das sich insbesondere zur Behandlung von Haarausfall, Haarwuchsstörungen, zytostatika induzierte Alopezie, Haarbrüchigkeit, Kopfschuppen bei trockener und öliger Seborrhoe, impetignisierter Ekzeme und Pyodermien der Kopfhaut, seborrhoisches Ekzem des Haarbodens, seborrhisches Begleitsymptome der androgenetischen Alopezie und zur Verlängerung der Lebensdauer der Haare eignet.The present invention relates to a hair care shampoo, which is particularly for the treatment of hair loss, hair growth disorders, cytostatic-induced alopecia, Hair brittleness, dandruff on dry and oily seborrhea, impetignized Eczema and pyoderma of the scalp, seborrheic eczema of the hair floor, accompanying seborrhic symptoms of androgenetic alopecia and for prolongation the life of the hair.
Als Krankeitsbild wird beispielsweise Haarausfall, Haarwuchsstörungen, Seborrhoe, Kopfschuppen oder eine chronische Haarbodenentzündung, Haarbalgentzündung oder eine entzündliche ekzematöse Kopfhautveränderung beobachtet.The clinical picture is, for example, hair loss, hair growth disorders, seborrhea, Dandruff or a chronic inflammation of the hair follicles, hair follicles or an inflammatory eczematous scalp change was observed.
Die Aufgabe der vorliegenden Erfindung ist es, hier Abhilfe zu schaffen und ein Haarkur-Pflege-Schampoo mit synergistischer Wirkung durch Kombination von Wirkstoffen zur Verfügung zu stellen.The object of the present invention is to remedy this and a Hair treatment care shampoo with synergistic effect by combining To provide active ingredients.
Erfindungsgemäß wird das dadurch erreicht, daß man ein Haarkur-Pflege-Shampoo, bestehend aus mindestens den Wirkstoffen:According to the invention this is achieved by using a hair care shampoo, consisting of at least the active ingredients:
- a) oxidierte oder reduzierte Enantiomere der α-Liponsäure, Dihydroliponsäure (Racemat) oder deren Ester, 6,8-Bisnorliponsäure, Tetranorliponsäure oder die 1,2- Dithiacyclopentan-3-butylsulfonsäure oder ihre Alkalisalze in einer Konzentration von beispielsweise 0,2 bis 10%, vorzugsweise 0,5 bis 4% unda) Oxidized or reduced enantiomers of α-lipoic acid, dihydrolipoic acid (Racemate) or its esters, 6,8-bisnorliponic acid, tetranorliponic acid or the 1,2- Dithiacyclopentan-3-butylsulfonic acid or its alkali salts in a concentration of for example 0.2 to 10%, preferably 0.5 to 4% and
- b) ein oder mehrere Kombinationspartner, wie Selensalzen, Dinatriumsalz, Kaliumsalz eines Kondensationsproduktes aus Laurinsäure und Eiweißhydrolysaten, Palmkernfettsäure-Sarkosid des Methyltaurins, Palmölkernfettsäure-Sarkosid des Triethanolamins, Natriumsalz eines Kondensationsproduktes aus Undecylensäure, wasserlöslichen Vitamin E oder F, Ascorbinsäure, Bierextrakt, Kamillenblütenextrakt oder Farbkonzentraten einsetzt.b) one or more combination partners, such as selenium salts, disodium salt, potassium salt a condensation product of lauric acid and protein hydrolyzates, Palm kernel fatty acid sarcoside of methyl taurine, palm kernel fatty acid sarcoside of Triethanolamine, sodium salt of a condensation product from undecylenic acid, water soluble vitamin E or F, ascorbic acid, beer extract, chamomile flower extract or color concentrates.
Das Haarkur-Pflegeschampoo kann beispielsweise bestehen aus:The hair care shampoo can consist of:
- a) oxidierten oder reduzierten Enantiomeren der α-Liponsäure, Dihydroliponsäure (Racemat) oder deren Ester, 6,8-Bisnorliponsäure, Tetranorliponsäure oder die 1,2- Dithiacyclopentan-3-butylsulfonsäure oder ihren Alkalisalze in einer Konzentration von beispielsweise 0,2 bis 8%, vorzugsweise 0,5 bis 4% und a) Oxidized or reduced enantiomers of α-lipoic acid, dihydrolipoic acid (Racemate) or its esters, 6,8-bisnorliponic acid, tetranorliponic acid or the 1,2- Dithiacyclopentan-3-butylsulfonic acid or its alkali salts in a concentration of for example 0.2 to 8%, preferably 0.5 to 4% and
- b) Natrium-Selenit, wasserlöslichen Vitamin E oder F, KM BRONIDOX L®, Kamillenblütenextrakt, TEXAPON EVR®, TEXAPON N25®, TEXAPON MLS®, TEXAPON N40®, TEXAPON N70®, TEXAPON MG®, EUPERLAN PK 776®, EUPERLAN PK 771®, COMPERLAN KD®, COMPERLAN 100®, COMPERLAN LS®, DEHYTON K®, Kokosfettsäure-diethanolamid, Fettalkoholethersulfat, Na-Laurylethersulfat, NUTRILAN I®, LAMERCIN 50-80®, Natriumchlorid, Konservierungsmittel, Parfümöl, Bierextrakt oder Farbkonzentraten.b) sodium selenite, water-soluble vitamin E or F, KM BRONIDOX L®, Chamomile flower extract, TEXAPON EVR®, TEXAPON N25®, TEXAPON MLS®, TEXAPON N40®, TEXAPON N70®, TEXAPON MG®, EUPERLAN PK 776®, EUPERLAN PK 771®, COMPERLAN KD®, COMPERLAN 100®, COMPERLAN LS®, DEHYTON K®, coconut fatty acid diethanolamide, fatty alcohol ether sulfate, Na lauryl ether sulfate, NUTRILAN I®, LAMERCIN 50-80®, sodium chloride, Preservatives, perfume oil, beer extract or color concentrates.
Die α-Liponsäure ist chemisch gesehen 1,2-Dithia-cyclopentan-3-valerieansäure und ist in Form des R-Enantiomers in Pflanzen und Tieren weit verbreitet. Sie wirkt in vielen enzymatischen Reaktionen als Coenzym, stellt einen Wachstumsfaktor für manche Bakterien und Protozoen dar und wird bei der Behandlung von Knollenblätterpilzvergiftungen eingesetzt.The α-lipoic acid is chemically 1,2-dithia-cyclopentan-3-valerieneansäure and is widely used in plants and animals in the form of the R enantiomer. It acts as a coenzyme in many enzymatic reactions Growth factor for some bacteria and protozoa and is in the Treatment of tuberous poisoning used.
Weiterhin weist das α-Liponsäure-Racemat antiphlogistische, antinociceptive (analgetische) sowie zytoprotektive, neuroprotektive, antiallergische und antitumor Eigenschaften auf.Furthermore, the α-lipoic acid racemate has anti-inflammatory, antinociceptive (analgesic) as well as cytoprotective, neuroprotective, anti-allergic and anti-tumor Properties on.
Die reinen, optischen Enantiomeren der α-Liponsäure (R- und S-Form, das heißt R-α- Liponsäure und S-α-Liponsäure) sind im Gegensatz zu dem Racemat wirksamer. Das R-Enantiomer ist vorwiegend antiphlogistisch und das S-Enantiomer antinociceptiv wirksam, wobei die antiphlogistische Wirkung des R-Enantiomer beispielsweise um einen Faktor 10 stärker ist als diejenige des Racemats.The pure, optical enantiomers of α-lipoic acid (R and S forms, i.e. R-α- In contrast to the racemate, lipoic acid and S-α-lipoic acid) are more effective. The R enantiomer is predominantly anti-inflammatory and the S enantiomer antinociceptive effective, the anti-inflammatory effect of the R enantiomer for example is a factor 10 stronger than that of the racemate.
Die antinociceptive (analgetische) Wirkung des S-Enantiomer ist beispielsweise um bis 6 Faktoren stärker als diejenigen des Racemats.The antinociceptive (analgesic) effect of the S enantiomer is, for example, up to 6 factors stronger than those of the racemate.
Die Enantiomeren der α-Liponsäure stellen daher im Vergleich zu dem Racemat sehr viel spezifischere und stärkerer wirksame Wirkstoffe dar.The enantiomers of α-lipoic acid are therefore very high compared to the racemate much more specific and powerful active ingredients.
Diese Wirkungen sind in EP-A 901 213 405 beschrieben.These effects are described in EP-A 901 213 405.
Dieser Synergismus wird vermutet durch den Schutz des Elastins, einem Bestandteil des Bindegewebes der Kopfhaut, durch die erfindungsgemäße Kombination mit der α-Liponsäure. Durch die beschriebene bekannte antiphlogistische und Kalziumfängereigenschaften der α-Liponsäure kommt es zur Hemmung der katabolen Enzyme. This synergism is suspected by the protection of elastin, a component of the connective tissue of the scalp, by the combination according to the invention with the α-lipoic acid. Through the well-known anti-inflammatory and Calcium scavenger properties of α-lipoic acid inhibit the catabolic Enzymes.
Das Haarkur-Pflege-Schamoo kann beispielsweise in Tuben, Flaschen oder verschweißten Kunststoffbeuteln zur äußerlichen Anwendung vorliegen.The hair treatment care shamoo can, for example, be in tubes, bottles or welded plastic bags for external use.
100 g Lösung enthält:100 g solution contains:
100 g Lösung enthält:100 g solution contains:
100 g Lösung enthält:100 g solution contains:
100 g Lösung enthält:100 g solution contains:
100 g Lösung enthält:100 g solution contains:
100 g Lösung enthält:100 g solution contains:
100 g Lösung enthält:.100 g of solution contains:
Claims (4)
- a) oxidierte oder reduzierte Enantiomere der α-Liponsäure, Dihydroliponsäure (Racemat) oder deren Ester, 6,8-Bisnorliponsäure, Tetranorliponsäure oder die 1,2- Dithiacyclopentan-3-butylsulfonsäure oder ihre Alkalisalze in einer Konzentration von 0,2 bis 10% und
- b) einem oder mehreren Kombinationspartnern wie Selensalzen, Dinatriumsalz, Kaliumsalz eines Kondensationsproduktes aus Laurinsäure und Eiweißhydrolysaten, Palmkernfettsäure-Sarkosid des Methyltaurins, Palmölkernfettsäure-Sarkosid des Triethanolamins, Natriumsalz eines Kondensationsproduktes aus Undecylensäure, wasserlöslichen Vitamin E oder F, Ascorbinsäure, Bierextrakt, Kamillenblütenextrakt oder Farbkonzentraten.
- a) oxidized or reduced enantiomers of α-lipoic acid, dihydroliponic acid (racemate) or their esters, 6,8-bisnorliponic acid, tetranorliponic acid or 1,2-dithiacyclopentane-3-butylsulfonic acid or its alkali salts in a concentration of 0.2 to 10% and
- b) one or more combination partners, such as selenium salts, disodium salt, potassium salt of a condensation product from lauric acid and protein hydrolyzates, palm kernel fatty acid sarcoside of methyl taurine, palm oil kernel fatty acid sarcoside of triethanolamine, sodium salt of a condensation product from undecylenic acid, water-soluble vitamin E or F, bleach extract, ascorbate extract, ascorbate extract, ascorbate extract, ascorbate extract, ascorbate extract, ascorbate extract, ascorbate extract .
- a) oxidierten oder reduzierten Enantiomeren der α-Liponsäure, Dihydroliponsäure (Racemat) oder deren Ester, 6,8-Bisnorliponsäure, Tetranorliponsäure oder die 1,2- Dithiacyclopentan-3-butylsulfonsäure oder ihren Alkalisalze in einer Konzentration von 0,2 bis 8% und
- b) einem oder mehreren Kombinationspartnern wie Natrium-Selenit, wasserlöslichen Vitamin E oder F, KM BRONIDOX L®, Kamillenblütenextrakt, TEXAPON EVR®, TEXAPON N25®, TEXAPON MLS®, TEXAPON N40®, TEXAPON N70®, TEXAPON MGOR, EUPERLAN PK 776®, EUPERLAN PK 771®, GOMPERLAN KD®, COMPERLAN 100®, COMPERLAN LS®, DEHYTON K®, Kokosfettsäure diethanolamid, Fettalkoholethersulfat, Na-Laurylethersulfat, NUTRILAN I®, LAMERCIN 50-80®, Natriumchlorid, Konservierungsmittel, Parfümöl, Bierextrakt oder Farbkonzentraten besteht.
- a) oxidized or reduced enantiomers of α-lipoic acid, dihydroliponic acid (racemate) or their esters, 6,8-bisnorliponic acid, tetranorliponic acid or 1,2-dithiacyclopentane-3-butylsulfonic acid or its alkali salts in a concentration of 0.2 to 8% and
- b) one or more combination partners such as sodium selenite, water-soluble vitamin E or F, KM BRONIDOX L®, chamomile flower extract, TEXAPON EVR®, TEXAPON N25®, TEXAPON MLS®, TEXAPON N40®, TEXAPON N70®, TEXAPON MGOR, EUPERLAN PK 776 ®, EUPERLAN PK 771®, GOMPERLAN KD®, COMPERLAN 100®, COMPERLAN LS®, DEHYTON K®, coconut fatty acid diethanolamide, fatty alcohol ether sulfate, Na lauryl ether sulfate, NUTRILAN I®, LAMERCIN 50-80®, sodium chloride, preservative, perfume oil or beer extract Color concentrates exist.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4419783A DE4419783A1 (en) | 1994-06-06 | 1994-06-06 | Medicated shampoo for hair care and treatment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4419783A DE4419783A1 (en) | 1994-06-06 | 1994-06-06 | Medicated shampoo for hair care and treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE4419783A1 true DE4419783A1 (en) | 1995-12-07 |
Family
ID=6519935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE4419783A Withdrawn DE4419783A1 (en) | 1994-06-06 | 1994-06-06 | Medicated shampoo for hair care and treatment |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE4419783A1 (en) |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2738743A1 (en) * | 1995-09-19 | 1997-03-21 | Oreal | USE OF ASCORBIC ACID AS AN ACTIVE INGREDIENT FOR THE TREATMENT OF SEBORRHEA IN A COSMETIC AND / OR DERMATOLOGICAL COMPOSITION |
| WO1996019099A3 (en) * | 1995-08-25 | 1997-04-10 | Lvmh Rech | Use of vitamin c or derivatives or analogues thereof for promoting skin elastin synthesis |
| WO1997026892A1 (en) * | 1996-01-26 | 1997-07-31 | Laboratoires Carilene | Combinations of peroxide lipids and organosilicon compounds, cosmetic and dermatological compositions containing same, and uses thereof, in particular for treating alopecia |
| WO2001093824A1 (en) * | 2000-06-06 | 2001-12-13 | Basf Aktiengesellschaft | Use of an (r)-enantiomer of lipoic acid in cosmetics and dermatologicals |
| EP1172110A3 (en) * | 2000-07-07 | 2003-09-17 | Basf Aktiengesellschaft | Use of lipoic acid as a bioavailaty enhancer of mineral salts |
| WO2002076410A3 (en) * | 2001-03-23 | 2003-09-25 | Beiersdorf Ag | Cosmetic and dermatological preparations comprising a content of a hop extract or hop-malt extract |
| AT412703B (en) * | 2001-12-04 | 2005-06-27 | Vis Vitalis Lizenz & Handels | USE OF SELIGENICAL PREPARATIONS FOR TOPICAL OR BUCCAL USE |
| EP1515715A4 (en) * | 2002-06-26 | 2006-06-14 | Perricone Nicholas V Dr | Hair and nail treatments using alkanolamines |
| WO2007140856A1 (en) * | 2006-06-08 | 2007-12-13 | Henkel Ag & Co. Kgaa | Oxidative hair treatment with reduced hair damage |
| WO2008074579A1 (en) * | 2006-12-20 | 2008-06-26 | Henkel Ag & Co. Kgaa | Hair color change which protects the skin |
| WO2008110223A3 (en) * | 2007-03-15 | 2009-11-05 | Henkel Ag & Co. Kgaa | Perming agent comprising capillary filament structures |
| US20100209375A1 (en) * | 2008-12-11 | 2010-08-19 | Maxime Deboni | Process for treating keratin fibers with at least one heterocyclic disulfide entity in the presence of at least one reducing agent, optionally heat, and optionally at alkaline ph. |
| FR2956813A1 (en) * | 2010-02-26 | 2011-09-02 | Lea Lab | Shampoo, useful for washing and/or hair care and scalp, comprises detersive surfactant component comprising an anionic detergent surfactant, emollient derived from vegetable oil, an active agent and water |
| WO2012080223A1 (en) | 2010-12-15 | 2012-06-21 | Sigea S.R.L. | Use of glycosaminoglycan lipoate esters in the trichology field |
| WO2015090856A1 (en) * | 2013-12-18 | 2015-06-25 | Henkel Ag & Co. Kgaa | Hair treatment means having a specific conditioning means combination containing lipoic acid ester |
-
1994
- 1994-06-06 DE DE4419783A patent/DE4419783A1/en not_active Withdrawn
Cited By (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996019099A3 (en) * | 1995-08-25 | 1997-04-10 | Lvmh Rech | Use of vitamin c or derivatives or analogues thereof for promoting skin elastin synthesis |
| GB2308811A (en) * | 1995-08-25 | 1997-07-09 | Lvmh Rech | Use of vitamin C or derivatives or analogues thereof for promoting skin elastic synthesis |
| BE1009858A5 (en) * | 1995-08-25 | 1997-10-07 | Lvmh Rech | Use of vitamin c or derivatives or similar to stimulate the synthesis of skin elastin. |
| US5801192A (en) * | 1995-08-25 | 1998-09-01 | Lvmh Recherche | Use of vitamin C or derivatives or analogues thereof promoting skin elastin synthesis |
| ES2129013A1 (en) * | 1995-08-25 | 1999-05-16 | Lvmh Rech | Use of vitamin c or derivatives or analogues thereof for promoting skin elastin synthesis |
| GB2308811B (en) * | 1995-08-25 | 2000-04-05 | Lvmh Rech | Use of vitamin C or derivatives or analogues thereof for promoting skin elastin synthesis |
| FR2738743A1 (en) * | 1995-09-19 | 1997-03-21 | Oreal | USE OF ASCORBIC ACID AS AN ACTIVE INGREDIENT FOR THE TREATMENT OF SEBORRHEA IN A COSMETIC AND / OR DERMATOLOGICAL COMPOSITION |
| EP0771557A1 (en) * | 1995-09-19 | 1997-05-07 | L'oreal | Use of ascorbic acid as the actif for the treatment of seborrhea in a cosmetic and/or dermatalogical composition |
| WO1997026892A1 (en) * | 1996-01-26 | 1997-07-31 | Laboratoires Carilene | Combinations of peroxide lipids and organosilicon compounds, cosmetic and dermatological compositions containing same, and uses thereof, in particular for treating alopecia |
| FR2744017A1 (en) * | 1996-01-26 | 1997-08-01 | Carilene Lab | ASSOCIATIONS OF PEROXIDIC LIPIDS AND ORGANOSILIC COMPOUNDS, COSMETIC AND DERMATOLOGICAL COMPOSITIONS CONTAINING SAME AND THEIR APPLICATIONS IN PARTICULAR FOR THE TREATMENT OF ALOPECIA |
| WO2001093824A1 (en) * | 2000-06-06 | 2001-12-13 | Basf Aktiengesellschaft | Use of an (r)-enantiomer of lipoic acid in cosmetics and dermatologicals |
| EP1172110A3 (en) * | 2000-07-07 | 2003-09-17 | Basf Aktiengesellschaft | Use of lipoic acid as a bioavailaty enhancer of mineral salts |
| US6887894B2 (en) | 2000-07-07 | 2005-05-03 | Basf Aktiengesellschaft | Use of lipoic acid for improving the bioavailability of mineral salts |
| WO2002076410A3 (en) * | 2001-03-23 | 2003-09-25 | Beiersdorf Ag | Cosmetic and dermatological preparations comprising a content of a hop extract or hop-malt extract |
| AT412703B (en) * | 2001-12-04 | 2005-06-27 | Vis Vitalis Lizenz & Handels | USE OF SELIGENICAL PREPARATIONS FOR TOPICAL OR BUCCAL USE |
| EP1515715A4 (en) * | 2002-06-26 | 2006-06-14 | Perricone Nicholas V Dr | Hair and nail treatments using alkanolamines |
| WO2007140856A1 (en) * | 2006-06-08 | 2007-12-13 | Henkel Ag & Co. Kgaa | Oxidative hair treatment with reduced hair damage |
| WO2008074579A1 (en) * | 2006-12-20 | 2008-06-26 | Henkel Ag & Co. Kgaa | Hair color change which protects the skin |
| WO2008110223A3 (en) * | 2007-03-15 | 2009-11-05 | Henkel Ag & Co. Kgaa | Perming agent comprising capillary filament structures |
| US20100209375A1 (en) * | 2008-12-11 | 2010-08-19 | Maxime Deboni | Process for treating keratin fibers with at least one heterocyclic disulfide entity in the presence of at least one reducing agent, optionally heat, and optionally at alkaline ph. |
| FR2956813A1 (en) * | 2010-02-26 | 2011-09-02 | Lea Lab | Shampoo, useful for washing and/or hair care and scalp, comprises detersive surfactant component comprising an anionic detergent surfactant, emollient derived from vegetable oil, an active agent and water |
| WO2012080223A1 (en) | 2010-12-15 | 2012-06-21 | Sigea S.R.L. | Use of glycosaminoglycan lipoate esters in the trichology field |
| WO2015090856A1 (en) * | 2013-12-18 | 2015-06-25 | Henkel Ag & Co. Kgaa | Hair treatment means having a specific conditioning means combination containing lipoic acid ester |
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