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DE112007002932T8 - Vierfarben DNA-Sequenzierung mittels Synthese unter Verwendung von abspaltbaren, reversiblen, fluoreszierenden Nucleotidterminatoren - Google Patents

Vierfarben DNA-Sequenzierung mittels Synthese unter Verwendung von abspaltbaren, reversiblen, fluoreszierenden Nucleotidterminatoren Download PDF

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Publication number
DE112007002932T8
DE112007002932T8 DE200711002932 DE112007002932T DE112007002932T8 DE 112007002932 T8 DE112007002932 T8 DE 112007002932T8 DE 200711002932 DE200711002932 DE 200711002932 DE 112007002932 T DE112007002932 T DE 112007002932T DE 112007002932 T8 DE112007002932 T8 DE 112007002932T8
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cleavable
reversible
synthesis
dna sequencing
fluorescent nucleotide
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DE112007002932T5 (de
DE112007002932B4 (de
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Jingyue Ju
Dae Hyun Kim
Lanrong Bi
Qinglin Meng
Xiaoxu Li
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Columbia University in the City of New York
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Columbia University in the City of New York
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6823—Release of bound markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
DE112007002932.3T 2006-12-01 2007-11-30 Vierfarben DNA-Sequenzierung mittels Synthese unter Verwendung von abspaltbaren, reversiblen, fluoreszierenden Nucleotidterminatoren Active DE112007002932B4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87224006P 2006-12-01 2006-12-01
US60/872,240 2006-12-01
PCT/US2007/024646 WO2008069973A2 (en) 2006-12-01 2007-11-30 Four-color dna sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators

Publications (3)

Publication Number Publication Date
DE112007002932T5 DE112007002932T5 (de) 2009-10-08
DE112007002932T8 true DE112007002932T8 (de) 2009-11-26
DE112007002932B4 DE112007002932B4 (de) 2015-08-06

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DE112007002932.3T Active DE112007002932B4 (de) 2006-12-01 2007-11-30 Vierfarben DNA-Sequenzierung mittels Synthese unter Verwendung von abspaltbaren, reversiblen, fluoreszierenden Nucleotidterminatoren

Country Status (4)

Country Link
US (9) US7883869B2 (de)
DE (1) DE112007002932B4 (de)
GB (1) GB2457402B (de)
WO (1) WO2008069973A2 (de)

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* Cited by examiner, † Cited by third party
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US9528151B2 (en) 2016-12-27
US8298792B2 (en) 2012-10-30
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US20190136308A1 (en) 2019-05-09
DE112007002932B4 (de) 2015-08-06
WO2008069973A2 (en) 2008-06-12
US20120021408A1 (en) 2012-01-26
US20200208211A1 (en) 2020-07-02
US20140315191A1 (en) 2014-10-23
US11939631B2 (en) 2024-03-26
GB2457402A (en) 2009-08-19
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US20170114403A1 (en) 2017-04-27
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US20240318245A1 (en) 2024-09-26
US20210381043A1 (en) 2021-12-09
US7883869B2 (en) 2011-02-08
US11098353B2 (en) 2021-08-24
US10000801B2 (en) 2018-06-19
US20130280700A1 (en) 2013-10-24
US20100092952A1 (en) 2010-04-15

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