DE10161885A1 - Cleaning products based on oil-containing, microemulsions - Google Patents

Abstract

The present invention relates to cleaning products and processes for their production based on oil-containing microemulsions which are aesthetic and also foamable and which can be used as shower gels, shampoos, cleansing preparations, hand-washing products, bath preparations, make-up removers or shaving products. The products can be low-viscosity or gel-like, can foam lightly or strongly and / or can be used as antibacterial rinse-off formulations. The cleaning products are very mild to the skin and aesthetically transparent. The microemulsions can serve as an impregnation medium for wipes, tissues that are applied wet or dry by the consumer. The microemulsions can also be applied from a pump foamer.

Description

The present invention relates to cleaning products based on oil Microemulsions and the process for their preparation, which are nevertheless aesthetic and are used as shower gels, shampoos, cleansing preparations, Hand washing products, bath preparations, make-up removers or shaving products can be used. The products can be low viscosity or gel-like, light or foam strongly and / or used as antibacterial rinse-off formulations become. The cleaning products are very mild to the skin and aesthetic. The Microemulsions can serve as a soaking medium for wipes, tissues that are wet or applied dry by the consumer or from a pumpoamer be applied.

Cosmetic treatment of the skin and hair also includes cleaning them. Cleaning means both removing unwanted dirt, removing it Germination of all kinds as well as an increase in psychological and physical well-being. Preparations containing surfactants are primarily suitable for cleaning.

Surfactants are amphiphilic substances that dissolve organic, non-polar substances in water can. Due to their specific molecular structure, they provide at least a hydrophilic and a hydrophobic part of the molecule, for reducing the Surface tension of the water, the wetting of the skin, the relief of Dirt removal and solution, easy rinsing and - if desired - for Foam control.

• - anionische Tenside,
• - kationische Tenside,
• - amphotere Tenside und
• - nichtionische Tenside.

The hydrophilic parts of a surfactant molecule are mostly polar functional groups, for example -COO ^- , -OSO ₃ ^2- -SO ₃ ^- , while the hydrophobic parts generally represent non-polar hydrocarbon radicals. Surfactants are generally classified according to the type and charge of the hydrophilic part of the molecule. There are four groups:

• - anionic surfactants,
• - cationic surfactants,
• - amphoteric surfactants and
• - nonionic surfactants.

Anionic surfactants generally have carboxylate, sulfate or sulfonate groups as functional groups. In aqueous solution they form negatively charged organic ions in an acidic or neutral environment. Cationic surfactants are characterized almost exclusively by the presence of a quaternary ammonium group. In aqueous solution, they form positively charged organic ions in an acidic or neutral environment. Amphoteric surfactants contain both anionic and cationic groups and accordingly behave in aqueous solution like anionic or cationic surfactants depending on the pH. They have a positive charge in a strongly acidic environment and a negative charge in an alkaline environment. In the neutral pH range, however, they are zwitterionic, as the following example should illustrate:
RNH ₂ ⁺ CH ₂ CH ₂ COOH X ^- (at pH = 2); X ^- = any anion, e.g. B. Cl ^- ;
RNH ₂ ⁺ CH ₂ CH ₂ COO ^- (at pH = 7);
RNHCH ₂ CH ₂ COO ^- B ⁺ (at pH = 12); B ⁺ = any cation, e.g. B. Na ⁺ .

Polyether chains are typical of non-ionic surfactants. Form non-ionic surfactants no ions in aqueous medium.

Common manifestations of cosmetic or dermatological preparations and Cleaning products are finely dispersed multiphase systems in which one or there are several fat or oil phases in addition to one or more water phases. The actual emulsions are the most extensive of these systems widespread.

In simple emulsions there are finely dispersed droplets of the second phase (water droplets in W / O or lipid vesicles in O / W emulsions) enclosed in an emulsifier shell. The droplet diameters of the common emulsions are in the range from approx. 1 µm to approx. 50 µm. Such "macroemulsions" are milky white and opaque without any additional coloring additives. Finer "macroemulsions", whose droplet diameters are in the range from approx. 4 × 10 ^-1 µm to approx. 1 µm, are again blue-white in color and opaque, without coloring additives.

Micellar and molecular solutions with particle diameters smaller than approx. 10 ^-2 µm are reserved to appear clear and transparent.

The droplet diameter of transparent or translucent microemulsions, on the other hand, is in the range from about 10 ^-2 µm to about 4 × 10 ^-1 µm. Such microemulsions are usually of low viscosity. The viscosity of many O / W type microemulsions is comparable to that of water.

The advantage of microemulsions is that active substances are more finely dispersed in the disperse phase can be present as in the disperse phase of "macroemulsions". Another The advantage is that they are sprayable due to their low viscosity.

A disadvantage of the microemulsions of the prior art is that they are always high Content of one or more emulsifiers must be used because the low Droplet size requires a high interface between the phases, which in the Usually must be stabilized by emulsifiers.

In itself, the use of the usual cosmetic emulsifiers is harmless. Nevertheless, emulsifiers, like ultimately every chemical substance, can in individual cases allergic or hypersensitivity reactions cause.

Microemulsions based on anionic surfactants are known. In EP 0529883 Preparations are described in addition to lauryl ether sulfate and betaine contain cationic deposition polymer. The disadvantage is that on the one hand only silicone oils can be used and on the other hand the proportion of oil only 1 wt .-% in In contrast to 18 wt .-% of surfactants. The emulsification of more oil fractions while maintaining transparency is not realized.

Transparent systems are obtained when there is no water in O / W microemulsions is used more. However, these systems are then not an O / W microemulsion to be understood, but as pure oil bases, oil baths, as in DE 197 12 678 described.

Problematic in the provision of microemulsions with anionic, Cationic or amphoteric surfactants is still that the oil components only are very difficult to use because the surfactants are often too water-soluble and therefore hardly have any emulsifying properties. Furthermore, the surfactants mostly contain salts, that have a great influence on the emulsifying power. Further must Mixtures of surfactants often only with acids such as citric acid to pH values between 5 to 7 can be set, which also changes the Interface properties and thus often the incorporation of Oil components difficult while maintaining transparency. The state of the Technology lacks a manufacturing regulation that is more oily and yet more transparent Microemulsions that are mild to the skin as cleaning products.

DE 35 34 733 describes microemulsions, but the proportion of solubilized oil components in the range of 0.5 to 3 wt .-% is low. The The problem of incorporating larger amounts of oil is also clear in WO 9948473, the incorporation of only 0.5-1% by weight of oil is mentioned here.

WO 0047166 describes microemulsions based on MIPA laureth sulfate described. In the examples Laureth-9, Myreth-9, Sodium laureth-10 carboxylic acid, ethoxylated castor oil and cocamidopropyl betaine used. From the examples it can be seen that the ratio of surfactants to solubilized oil is very large. This disadvantage of the surfactant mixture allows a maximum of 5% by weight To solubilize oil. Another problem with the combination cationic substances with anionic surfactants often precipitate the corresponding surfactant mixture due to the electrostatic attraction of both Leads substances is not mentioned in WO 0047166.

EP 668754 describes transparent preparations which are anionic Surfactants, 3-15% by weight oil, a polar, nonionic emulsifier (HLB 5-10) and 1-5% by weight an ethoxylated monoglyceride ether. The disadvantage is that only Lauryl ether sulfate can be used, the formulas are not low viscosity like water can be adjusted and a special polar emulsifier (Rewoderm LIS 75) is required.

DE 44 11 557 describes microemulsions which contain 8% by weight of oil. As In addition to lauryl ether sulfate, surfactants are only low ethoxylated W / O emulsifiers (Ceteth-5, Oleth-5) used. The disadvantage is that the mixtures foam little and contain no conditioning agents. It is also known that foams only A flash foam is obtained from the anionic surfactant lauryl ether sulfate but quickly becomes unstable. Stability can be increased by cosurfactants such as betaine, glutamate, Sarcosinate or amphoacetate can be achieved, but this is not considered to be in DE 44 11 557 is considered advantageous. Also typically used for rinse-off products surfactant systems to be used are not described.

DE 197 55 488 describes microemulsions that either do very little Contain water or a lot of water. In the latter case, the microemulsions are however, characterized by a very high polyol content of 12-30% by weight. The mentioned oil phase consists of glyceryl oleate or cetyl alcohol, so that in cosmetic sense, it is therefore rather W / O emulsifiers and Consistency agent acts. The microemulsion described is strictly speaking from anionic surfactants such as lauryl ether sulfate, cocoglyceride and the aforementioned W / O emulsifiers. Only cetyl laurate (hexyl decanol laurate) is the real oil component with a share of 2.2 wt .-%. The solubilization of larger amounts of oil is obviously difficult here, too, since a total of 33.2% by weight of surfactants and W / O Emulsifiers are required to clearly disperse about 2% by weight of oil. The disadvantage is furthermore the high content of hexanediol of 12% by weight and short-chain glycerol esters such as Glyceryl caprylate of 12-15 wt .-%, as these substances are listed in the Concentrations are irritating to the skin.

An important point to note when developing cleaning products is their skin tolerance. The microemulsions described above are no information about their skin tolerance compared to corresponding oil-free surfactant mixtures or oil-containing emulsion products that were made with anionic surfactants. The choice of surfactants and the part right high use concentration of the surfactants seems to be responsible for this.

The object of the present invention is to prepare oil-containing cleaning products do not have the disadvantages of the known cleaning products exhibit. Another object of the present invention is to improve the state of the art Enrich technology and cleaning products and their manufacturing processes To provide that have a relatively high oil content and still aesthetic and above all are skin-friendly.

Another object of the present invention is oil-containing cleaning products to provide the sensory, pleasantly applied, distributed and can be washed off, the skin-care oil phase on the skin remains.

Furthermore, the problem of cleaning products has to be solved, which is relative have a high oil content but do not foam.

The tasks listed are solved by a process for the production of Microemulsions as cleaning preparations and the so produced Cleaning preparations according to the main claims. Subject of Subclaims are advantageous embodiments of the invention Preparations. The invention further includes the use of such Preparations.

• a) einem Primärtensid,
• b) einem oder mehrerer Cotenside,
• c) gegebenenfalls einem oder mehreren W/O-Emulgatoren,
• d) einer oder mehreren flüssig und/oder fester Ölphasen,
• e) gegebenenfalls einem Verdicker und
• f) der Zugabe von 0 bis 4 Gew.-% Salzen

erhalten werden, wobei bei konstanter Gesamttensidmenge das Primär-/Cotensid- Verhältnis variabel eingestellt werden kann und transparente Emulsionen erhalten werden. Die entsprechenden Mikroemulsionen helfen den Nachteilen des Standes der Technik ab. It was surprising and unforeseeable for the person skilled in the art that oil-containing microemulsions which can be used as cleaning products can be obtained by the combination of

• a) a primary surfactant,
• b) one or more cosurfactants,
• c) optionally one or more W / O emulsifiers,
• d) one or more liquid and / or solid oil phases,
• e) optionally a thickener and
• f) the addition of 0 to 4 wt .-% salts

are obtained, the primary / cosurfactant ratio being variable with a constant total amount of surfactant, and transparent emulsions being obtained. The corresponding microemulsions remedy the disadvantages of the prior art.

When it comes to solving the problems, there is the multifactorial dependency in manufacturing oily and, under certain circumstances, foaming microemulsions. Have so the factors, the type of oil phase used, the amount of oil, the pH, the Salinity and the primary / cosurfactant ratio, influence the transparency of the Microemulsion. The factors of pH, salinity, the amount of thickener, the W / O emulsifiers and the primary / cosurfactant ratio in turn influence the viscosity of the microemulsion. Nevertheless, surprisingly results in constant total surfactant content of a microemulsion with variable primary / cosurfactant Relationship.

It has proven advantageous that the primary surfactant, for example Laurether sulfate or lauryl sulfate, and the cosurfactant, for example betaines, Amphoacetate, glutamate or sarcosinate, with the same total surfactant content of e.g. B. 15% by weight, can be changed so that microemulsions continue to result. It variable primary / cosurfactant ratios of 14: 1, 13: 2, 11: 4, 9: 6 etc. can be set and a microemulsions is obtained in any case.

Recipes that have such flexibility in surfactant choice are advantageous because the foaming power as well as the compatibility of the depend strongly on the respective recipe.

These relationships have been known for oil-free surfactant blends but has not yet been fathomed in the oil-containing compositions. There Microemulsions are extremely sensitive to such variations because the Interface properties then change significantly, is due to the present invention an existing deficiency which is revealed in the above-described microemulsions, been fixed.

Foaming in particular is then advantageous because the consumer has a problem with it Associated cleaning performance. In general, oil-free formulations foam especially good if the surfactant / cosurfactant content or the surfactant ratio is chosen accordingly are. An advantage of recipes according to the invention is that they can also be used in the presence foaming of oil.

The microemulsions according to the invention are still varied relative surfactant proportions to one another is not fixed to a specific oil component. Active ingredients of different hydrophilicity / lipophilicity can thus be more easily can be used because the oil phase can be chosen flexibly. Furthermore, at Use of larger concentrations of oils and lipids, these themselves better at the Adhere to skin or hair, so that such products have a greater care potential exhibit. The use of larger concentrations of oil phases also enables that Adhesion of lipophilic, hydrophilic or surface-active agents, because of the remaining lipid film on the skin after showering, bathing, when Clean your face, wash your hands, remove makeup or after Shaving, the washability of these substances compared to microemulsions with small Oil phase or compared to oil-free surfactant mixtures is difficult.

The use of larger concentrations of oil components with a protective Lipid film is beneficial because the adhesion of surfactants after a rinse-off process is often problematic. This attachment can be more frequent with tenside-containing Products lead to intolerance to contact dermatitis. This disadvantage occurs in preparations according to the invention not because of a lipid deposition on the skin he follows.

Another advantage of the microemulsions according to the invention is their low viscosity Microemulsions with the advantages described above as well as microemulsion gels to formulate. For example, a low viscosity can be used for a bath additive Microemulsion can be beneficial, while for a shower product a gel-like consistency is cheaper because the product is then larger in the palm of your hand Quantity is available.

It is surprising and particularly advantageous that the oil-containing formulations according to the invention turn out much milder than oil-free compositions. Although a general one Theory for this is missing, it is assumed that the surfactants prefer to the Bind nanodroplets so that the free monomer content is very low. The free one Monomer content is known for corresponding intolerance reactions Cleaning products responsible. When using the invention Microemulsion forms a lipid film that is more protective than low-oil ones Compositions or compared to oil-free recipes. Therefore, they are Regreasing microemulsions, so that even more frequent applications in less Measure or not at all to remove the stratum corneum lipids, proteins or natural moisturizing factors. This effect is surprisingly only for those to observe oil-containing microemulsions according to the invention.

For use as a cleaning product, this is combined with another Significant advantage, since a pleasant, noticeable lipid film after application the skin remains, which naturally lacks low-lipid or lipid-free formulations. This is interesting for those consumers who look after the shower For example, do not apply cream afterwards.

It was also surprising that the incorporation of lipid-soluble or amphiphilic Active ingredients can be made easier compared to formulations with a low oil phase or compared to oil-free surfactant blends. Furthermore, at the same time or hydrophilic active ingredients can also be used advantageously.

The active ingredients adhere to the skin / hair after a rinse-off process facilitated.

Furthermore, the microemulsions according to the invention can be very well as Use impregnation medium for cloths and fabrics that are wet or dry Consumers can be applied. The compositions with the ultra-fine Droplets easily pull onto the fiber, which is an advantage. Further The soaked products can also be applied to the skin with water a foam.

The addition of a lipophilic co-emulsifier, such as glycerol ester, Propylene glycol ester, sorbitan ester low ethoyl. Glycerides, diglycerides or Triglycerides are advantageous because they lower the interfacial tension more can be. The lack of suitable co-emulsifiers in known preparations is explained by the fact that often only unstable formulations in the presence of oil The presence of the surfactants results or only simple emulsions are obtained can. This disadvantage has also been met according to the invention.

The influence of the salt content is only in microemulsions of the prior art insufficiently appreciated. This is despite the fact that the salinity is part of the success Manufacture of cosmetic cleaning products is significant. The surfactants often contain salts due to the manufacturing process. Often, oil-free Market formulations based on surfactants through the additional use of table salt Viscosity changed from low viscosity to gel-like. This high salinity can make it difficult to successfully produce microemulsions. The invention Microemulsions advantageously allow the additional salt content to be added between 0 and 4% by weight, provided the surfactants are not salt-free. For The microemulsions that are to be produced from salt-free surfactants would have to Salinity between 0 to 4 wt .-% plus the content of salts in the saline surfactants is present.

Furthermore, the prior art microemulsions are not aimed at how important the pH value is for the transparency of the mixtures. For example it is advantageous to adjust the pH to 5.5 using citric acid or other acids. However, the addition of acids changes the interfacial properties of the surfactants, so that a microemulsion with pH 8 knows by adding acid at pH 5.5 or can become unstable. In microemulsions according to the invention or Microemulsion gels succeed due to the relative conditions Surfactants / cosurfactants and W / O emulsifiers or by varying the salt content to obtain microemulsions regardless of the pH value, which in Formulations of the prior art are not possible.

• 1. Acylglutamate, beispielsweise Dinatriumacylglutamat, Natriumacylglutamat und Natrium Caprylic/Capric Glutamat,
• 2. Acylpeptide, beispielsweise Palmitoyl-hydrolysiertes Milchprotein, Natrium Cocoyl-hydrolysiertes Soja Protein und Natrium-/Kalium-Cocoyl-hydrolysiertes Kollagen, N-Cocoyl hydrolysiertes Weizenprotein, N-Cocoyl hydrolysierte Aminosäuren
• 3. Sarcosinate, beispielsweise Myristoyl Sarcosin, TEA-lauroyl Sarcosinat, Natriumlauroylsarcosinat und Natriumcocoylsarkosinat,
• 4. Taurate, beispielsweise Natriumlauroyltaurat und Natriummethylcocoyltaurat,
• 5. Acyllactylate, beispielsweise Lauroyllactylat, Caproyllactylat
• 6. Alaninate
• 7. Arginate, beispielsweise N-Lauroyl Arginat
• 8. Valinate, beispielsweise N-Lauroyl Valinat
• 9. Prolinate, beispielsweise N-Lauroyl Prolinat
• 10. Glycinat, beispielsweise N-Lauroyl Glycinat, Cocoamphopolycarboxyglycinat
• 11. Aspartate, beispielsweise N-Lauroyl Aspartate, Di-TEA-palmitoylaspartat
• 12. Propionate, beispielsweise Natrium Cocoamphopropionat

Carbonsäuren und Derivate, wie

• 1. Carbonsäuren, beispielsweise Laurinsäure, Aluminiumstearat, Magnesiumalkanolat und Zinkundecylenat,
• 2. Ester-Carbonsäuren, beispielsweise Calciumstearoyllactylat, Laureth-6-Citrat und Natrium PEG-4-Lauramidcarboxylat,
• 3. Ether-Carbonsäuren, beispielsweise Natriumlaureth-13-Carboxylat und Natrium PEG-6-Cocamide Carboxylat,
• 4. Natrium PEG-7 Olivenöl Carboxylat

Phosphorsäureester und Salze, wie beispielsweise DEA-Oleth-10-Phosphat und Dilaureth-4 Phosphat, Sulfonsäuren und Salze, wie

• 1. Acyl-isethionate, z. B. Natrium-/Ammoniumcocoyl-isethionat
• 2. Alkylarylsulfonate,
• 3. Alkylsulfonate, beispielsweise Natriumcocosmonoglyceridsulfat, Natrium C_12-14 Olefin-sulfonat, Natriumlaurylsulfoacetat und Magnesium PEG-3 Cocamidsulfat
• 4. Sulfosuccinate, beispielsweise Dioctylnatriumsulfosuccinat, Dinatriumlaurethsulfosuccinat, Dinatriumlaurylsulfosuccinat und Dinatriumundecylenamido-MEA-Sulfosuccinat

sowie Schwefelsäureester, wie

• 1. Alkylethersulfat, beispielsweise Natrium-, Ammonium-, Magnesium-, MIPA-, TIPA-Laurethsulfat, Natriummyrethsulfat und Natrium C_12-13-Parethsulfat,
• 2. Alkylsulfate, beispielsweise Natrium-, Ammonium- und TEA-Laurylsulfat.
• 3. Natriumalkylsulfate wie Natriumcetearylsulfat.

B. Kationische Tenside Vorteilhaft zu verwendende kationische Tenside sind

• 1. Alkylamine,
• 2. Alkylimidazole,
• 3. Ethoxylierte Amine und
• 4. Quaternäre Tenside.
• 5. Esterquats

It was also astonishing that, in addition to lauryl ether sulfate or lauryl sulfate, a variety of milder cosurfactants can be used as exemplary primary surfactants. The surfactants can advantageously be selected from: A. anionic surfactants acylamino acids and their salts, such as

• 1. acyl glutamates, for example disodium acyl glutamate, sodium acyl glutamate and sodium caprylic / capric glutamate,
• 2. Acyl peptides, for example palmitoyl-hydrolyzed milk protein, sodium cocoyl-hydrolyzed soy protein and sodium / potassium-cocoyl-hydrolyzed collagen, N-cocoyl-hydrolyzed wheat protein, N-cocoyl-hydrolyzed amino acids
• 3. sarcosinates, for example myristoyl sarcosin, TEA lauroyl sarcosinate, sodium lauroyl sarcosinate and sodium cocoyl sarcosinate,
• 4. taurates, for example sodium lauroyl taurate and sodium methyl cocoyl taurate,
• 5. Acyl lactylates, for example lauroyl lactylate, caproyl lactylate
• 6. Alaninate
• 7. Arginates, for example N-lauroyl arginate
• 8. Valinates, for example N-lauroyl valinate
• 9. Prolinates, for example N-lauroyl prolinate
• 10. Glycinate, for example N-lauroyl glycinate, cocoamphopolycarboxyglycinate
• 11. Aspartates, for example N-lauroyl aspartate, di-TEA-palmitoylaspartate
• 12. Propionates, for example sodium cocoamphopropionate

Carboxylic acids and derivatives, such as

• 1. carboxylic acids, for example lauric acid, aluminum stearate, magnesium alkanolate and zinc undecylenate,
• 2. ester carboxylic acids, for example calcium stearoyl lactylate, laureth-6 citrate and sodium PEG-4 lauramide carboxylate,
• 3. ether carboxylic acids, for example sodium laureth-13 carboxylate and sodium PEG-6 cocamide carboxylate,
• 4. Sodium PEG-7 olive oil carboxylate

Phosphoric acid esters and salts, such as, for example, DEA-oleth-10-phosphate and dilaureth-4 phosphate, sulfonic acids and salts, such as

• 1. acyl isethionates, e.g. B. Sodium / ammonium cocoyl isethionate
• 2. alkylarylsulfonates,
• 3. Alkyl sulfonates, for example sodium coconut monoglyceride sulfate, sodium C _12-14 olefin sulfonate, sodium lauryl sulfoacetate and magnesium PEG-3 cocamide sulfate
• 4. Sulfosuccinates, for example dioctyl sodium sulfosuccinate, disodium laureth sulfosuccinate, disodium lauryl sulfosuccinate and disodium undecylenamido MEA sulfosuccinate

as well as sulfuric acid esters, such as

• 1. alkyl ether sulfate, for example sodium, ammonium, magnesium, MIPA, TIPA laureth sulfate, sodium myreth sulfate and sodium C _12-13 pareth sulfate,
• 2. Alkyl sulfates, for example sodium, ammonium and TEA lauryl sulfate.
• 3. Sodium alkyl sulfates such as sodium cetearyl sulfate.

B. Cationic Surfactants Cationic surfactants to be used advantageously are

• 1. alkylamines,
• 2. alkylimidazoles,
• 3. Ethoxylated amines and
• 4. Quaternary surfactants.
• 5. Esterquats

Quaternary surfactants contain at least one N atom, which with 4 alkyl and / or Aryl groups is covalently linked. Regardless of the pH value, this leads to a positive charge. Advantageous quaternary surfactants are alkyl betaine, alkyl amidopropyl betaine and alkyl amidopropyl hydroxysulfain. Cationic surfactants can also be preferred in According to the present invention are selected from the group of quaternaries Ammonium compounds, especially benzyltrialkylammonium chlorides or bromides, such as, for example, benzyldimethylstearylammonium chloride Alkyltrialkylammonium salts, for example cetyltrimethylammonium chloride or bromide, Alkyldimethylhydroxyethylammonium chlorides or bromides, dialkyldimethylammonium chlorides or bromides, dialkyl ethoxylate dimethyl ammonium chlorides or bromides such as for example di (C14-C18) alkyl (EO) 3-20 dimethylammonium salts or Distearyl (EO) 5 dimethyl ammonium chloride and Distearyl (EO) 15 dimethyl ammonium chloride.

• 1. Acyl-/dialkylethylendiamin, beispielsweise Natriumacylamphoacetat, Dinatriumacylamphodipropionat, Dinatriumalkylamphodiacetat, Natriumacylamphohydroxypropylsulfonat, Dinatriumacylamphodiacetat und Natriumacylamphopropionat,
• 2. N-Alkylaminosäuren, beispielsweise Aminopropylalkylglutamid, Alkylaminopropionsäure, Natriumalkylimidodipropionat und Lauroamphocarboxyglycinat.

Alkylamidethyltrimethylammonium ether sulfates, alkylpyridinium salts, for example lauryl or cetylpyrimidinium chloride, imidazoline derivatives and compounds with a cationic character such as amine oxides, for example alkyldimethylamine oxides or alkylaminoethyldimethylamine oxides. Cetyltrimethylammonium salts are particularly advantageous. C. Amphoteric Surfactants Are amphoteric surfactants that can be used advantageously

• 1. acyl- / dialkylethylenediamine, for example sodium acylamphoacetate, disodium acylamphodipropionate, disodium alkylamphodiacetate, sodium acylamphohydroxypropylsulfonate, disodium acylamphodiacetate and sodium acylamphopropionate,
• 2. N-alkylamino acids, for example aminopropylalkylglutamide, alkylaminopropionic acid, sodium alkylimidodipropionate and lauroamphocarboxyglycinate.

The total surfactant content, consisting of primary surfactant and cosurfactant, is in the range from 1 to 30% by weight. The total surfactant content is preferably 25% by weight and that Primary / cosurfactant ratio can be set variably in the range 14: 1 to 1:14.

The droplets of the discontinuous oil phase can be one or more Crosslinking substances, so-called thickeners, connected to each other, the Crosslinker structure is characterized by at least one hydrophilic area, which has an extent which is suitable for the distance between the Bridging microemulsion droplets with each other, and by at least one hydrophobic Area which interacts with the microemulsion droplets in hydrophobic interaction can kick.

In WO 9628132 the backbone of a water soluble or in water dispersible thickener shown, the branching sites covalently to the Polymer-bonded hydrophobic groups can be represented. The hydrophobic residues can adhere to each other through hydrophobic interaction. To the Crosslinking sites can become microemulsion droplets due to hydrophobic Add interactions as well. It is basically irrelevant whether the "Immerse" hydrophobic residues or whether the hydrophobic residues are only superficial come into contact with the microemulsion droplets and more or less strongly these stick.

It is equally advantageous if the crosslinking agent, in the context of This description also referred to as a thickener, an independent Gel network forms, in which the microemulsion droplets then through hydrophobic Interaction are recorded (then there are so-called associative thickeners before), or whether the cohesion of the network through networking with the Microemulsion droplets in the nodes of the network is caused.

The crosslinking substances used according to the invention generally follow structural schemes as follows:


where B symbolizes a hydrophilic region of the respective crosslinker molecule and A each represents hydrophobic regions, which may also be of a different chemical nature within a molecule.

But also structure schemes like


and analogously formed, even more complex structures definitely fall within the scope of the invention presented here.

Structural diagrams also fall within the scope of the invention presented as follows:


where Z represents a central unit, which can be hydrophilic or hydrophobic and generally consists of an oligo- or polyfunctional molecular residue.

Of course, thickeners with a higher degree of branching also fall into the Scope of the present invention.

For example, Z in scheme (10) may consist of one glyceryl residue, three of which OH functions in areas B, which in turn, for example Polyoxyethylene chains of the same or different lengths can represent, and their terminals OH group are esterified with a longer-chain fatty acid. Also partial substitution Glycerin is conceivable, whereby structures can arise, which scheme (9) correspond.

The hydrophilic groups B can advantageously be chosen such that the crosslinker is overall water-soluble or at least dispersible in water, in which case the hydrophobic portion of groups A should be overcompensated.

For the structure scheme (1), for example, the following more specific structure schemes can be followed:




where R ₁ , R ₂ , R ₃ , R ₄ , R ₅ and R _{6 can} independently represent branched or unbranched, saturated or unsaturated, cyclic or chain-shaped aliphatic, aromatic or heteroaromatic radicals, for example branched or unbranched or cyclic alkyl or alkanoyl radicals , Aryl or aroyl radicals substituted or unsubstituted by alkyl or aryl substituents or also alkylated or arylated organylsilyl radicals. x means numbers which allow the entire molecule to be soluble or at least dispersible in water, typically selected from the range greater than 10, advantageously from the range 20-300. a and b are numbers which are chosen as a function of x in such a way that the total molecule has at least sufficient water solubility or water dispersibility. In individual cases, for example if the thickener is selected from the group of the derivatized polysaccharides, x can also have values much higher than 300, even several million. This is known per se to the person skilled in the art and requires no further explanation.

For the structure scheme (2), for example, the following more specific structure schemes can be followed:


where R ₁ , R ₂ and R _{3 can} independently represent branched or unbranched, saturated or unsaturated, cyclic or chain-like aliphatic, aromatic or heteroaromatic radicals, for example branched or unbranched or cyclic alkyl or alkanoyl radicals, substituted or unsubstituted by alkyl or aryl substituents Aryl or aroyl residues or also alkylated or arylated organylsilyl residues. x, y and z mean, independently of one another, numbers which allow the entire molecule to be soluble or at least dispersible in water, typically selected from the range greater than 10, advantageously from the range 20-300.

Partial substitution is also conceivable, where one or more of the indices x, y or z can assume the value zero and one or more of the radicals R ₁ , R ₂ or R ₃ can represent hydrogen atoms.

For the structure scheme (3), for example, the following more specific structure schemes can be followed:




where R ₁ , R ₂ , R ₃ and R _{4 can} independently represent branched or unbranched, saturated or unsaturated, cyclic or chain-shaped aliphatic, aromatic or heteroaromatic radicals, for example branched or unbranched or cyclic alkyl or alkanoyl radicals, with alkyl or aryl substituents Substituted or unsubstituted aryl or aroyl residues or also alkylated or arylated organylsilyl residues. u, v, w and x mean, independently of one another, numbers which allow the entire molecule to be soluble or at least dispersible in water, typically selected from the range greater than 10, advantageously from the range 20-300.

Here too, it goes without saying that partial substitution is conceivable, where one or more of the indices u, v, w, x can assume the value zero and one or more of the radicals R ₁ , R ₂ , R ₃ or R ₄ can represent hydrogen atoms. The substances naturally change into other structural schemes.

For the structure scheme (9), for example, the following more specific structure schemes can be followed:


where R ₁ , R ₂ , R ₃ and R _{4 can} independently represent branched or unbranched, saturated or unsaturated, cyclic or chain-shaped aliphatic, aromatic or heteroaromatic radicals, for example branched or unbranched or cyclic alkyl or alkanoyl radicals, with alkyl or aryl substituents Substituted or unsubstituted aryl or aroyl residues or also alkylated or arylated organylsilyl residues. x and y mean, independently of one another, numbers which allow the entire molecule to be soluble or at least dispersible in water, typically selected from the range greater than 10, advantageously from the range 20-300.

For the structure scheme (10), for example, the following more specific structure schemes can be followed:


where R ₁ , R ₂ and R _{3 can} independently represent branched or unbranched, saturated or unsaturated, cyclic or chain-shaped aliphatic, aromatic or heteroaromatic radicals, for example branched or unbranched or cyclic alkyl or alkanoyl radicals, substituted by alkyl or aryl substituents or unsubstituted aryl or aroyl residues or also alkylated or arylated organylsilyl residues. x, y and z mean, independently of one another, numbers which allow the entire molecule to be soluble or at least dispersible in water, typically selected from the range greater than 10, advantageously from the range 20-300.

For the structure scheme (11), for example, the following more specific structure scheme can be followed:


where R ₁ , R ₂ , R ₃ and R _{4 can} independently represent branched or unbranched, saturated or unsaturated, cyclic or chain-shaped aliphatic, aromatic or heteroaromatic radicals, for example branched or unbranched or cyclic alkyl or alkanoyl radicals, with alkyl or aryl substituents Substituted or unsubstituted aryl or aroyl residues or also alkylated or arylated organylsilyl residues. u, v, w and x mean, independently of one another, numbers which allow the entire molecule to be soluble or at least dispersible in water, typically selected from the range greater than 10, advantageously from the range 20-300. k, l, m and n can independently represent numbers from 0 to 50.

For the structure scheme (12), for example, the following more specific structure scheme can be followed:


where R ₁ , R ₂ , R ₃ , R ₄ and R _{5 can} independently represent branched or unbranched, saturated or unsaturated, cyclic or chain-like aliphatic, aromatic or heteroaromatic radicals, for example branched or unbranched or cyclic alkyl or alkanoyl radicals, with alkyl - or aryl substituents substituted or unsubstituted aryl or aroyl radicals or also alkylated or arylated organylsilyl radicals. u, v, w, x and y mean, independently of one another, numbers which allow the entire molecule to be soluble or at least dispersible in water, typically selected from the range greater than 10, advantageously from the range 20-100.

For the structure scheme (13), for example, the following more specific structure scheme can be followed:


where R ₁ , R ₂ , R ₃ , R ₄ , R ₅ and R _{6 can} independently represent branched or unbranched, saturated or unsaturated, cyclic or chain-shaped aliphatic, aromatic or heteroaromatic radicals, for example branched or unbranched or cyclic alkyl or alkanoyl radicals , Aryl or aroyl radicals substituted or unsubstituted by alkyl or aryl substituents or also alkylated or arylated organylsilyl radicals. u, v, w, x, y and z mean, independently of one another, numbers which allow the entire molecule to be soluble or at least dispersible in water, typically selected from the range greater than 10, advantageously from the range 20-1000.

It may also be advantageous to use the structure schemes described above to change that branching occurs again at the end of the thickener molecule, for example as it is realized in the group of so-called dendrimers.

• - der Polyethylenglycolether der allgemeinen Formel R-O-(-CH₂-CH₂-O-)_n-R', wobei R und R' unabhängig voneinander verzweigte oder unverzweigte Alkyl-, Aryl- oder Alkenylreste und n eine Zahl größer als 100 darstellen,
• - der veretherten Fettsäureethoxylate der allgemeinen Formel R-COO-(-CH₂-CH₂-O-)_n-R', wobei R und R' unabhängig voneinander verzweigte oder unverzweigte Alkyl-, Aryl- oder Alkenylreste und n eine Zahl größer als 100 darstellen,
• - der veresterten Fettsäureethoxylate der allgemeinen Formel R-COO-(-CH₂-CH₂-O-)_n-C(O)-R', wobei R und R' unabhängig voneinander verzweigte oder unverzweigte Alkyl-, Aryl- oder Alkenylreste und n eine Zahl größer als 100 darstellen, der Polypropylenglycolether der allgemeinen Formel R-O-(-CH₂-CH(CH₃)-O-)_n-R', wobei R und R' unabhängig voneinander verzweigte oder unverzweigte Alkyl-, Aryl- oder Alkenylreste und n eine Zahl größer als 100 darstellen, der veresterten Fettsäurepropoxylate der allgemeinen Formel R-COO-(-CH₂-CH(CH₃)-O-)_n-C(O)-R', wobei R und R' unabhängig voneinander verzweigte oder unverzweigte Alkyl-, Aryl- oder Alkenylreste und n eine Zahl größer als 100 darstellen, der Polypropylenglycolether der allgemeinen Formel R-O-X_n-Y_m-R', wobei R und R' unabhängig voneinander verzweigte oder unverzweigte Alkyl-, Aryl- oder Alkenylreste darstellen, wobei X und Y nicht identisch sind und jeweils entweder eine Oxyethylengruppe oder eine Oxypropylengruppe und n und m unabhängig voneinander Zahlen darstellen, deren Summe größer als 100 ist
• - der veretherten Fettsäurepropoxylate der allgemeinen Formel R-COO-X_n-Y_m-R', wobei R und R' unabhängig voneinander verzweigte oder unverzweigte Alkyl-, Aryl- oder Alkenylreste darstellen, wobei X und Y nicht identisch sind und jeweils entweder eine Oxyethylengruppe oder eine Oxypropylengruppe und n und m unabhängig voneinander Zahlen darstellen, deren Summe größer als 100 ist

Those selected from the group have proven to be particularly suitable crosslinkers

• the polyethylene glycol ether of the general formula RO - (- CH ₂ -CH ₂ -O-) _n -R ', where R and R' independently of one another are branched or unbranched alkyl, aryl or alkenyl radicals and n is a number greater than 100,
• - The etherified fatty acid ethoxylates of the general formula R-COO - (- CH ₂ -CH ₂ -O-) _n -R ', where R and R' independently of one another are branched or unbranched alkyl, aryl or alkenyl radicals and n is a number greater than 100 represent
• - The esterified fatty acid ethoxylates of the general formula R-COO - (- CH ₂ -CH ₂ -O-) _n -C (O) -R ', where R and R' independently of one another are branched or unbranched alkyl, aryl or alkenyl radicals and n represents a number greater than 100, the polypropylene glycol ether of the general formula RO - (- CH ₂ -CH (CH ₃ ) -O-) _n -R ', where R and R' independently of one another are branched or unbranched alkyl, aryl or Alkenyl radicals and n represent a number greater than 100, the esterified fatty acid propoxylates of the general formula R-COO - (- CH ₂ -CH (CH ₃ ) -O-) _n -C (O) -R ', where R and R' independently branched or unbranched alkyl, aryl or alkenyl radicals and n represent a number greater than 100, the polypropylene glycol ether of the general formula ROX _n -Y _m -R ', where R and R' independently of one another branched or unbranched alkyl, aryl or Represent alkenyl radicals, where X and Y are not identical and each have either an oxyethylene group or an oxypropylene group e and n and m independently represent numbers whose sum is greater than 100
• - The etherified fatty acid propoxylates of the general formula R-COO-X _n -Y _m -R ', where R and R' independently of one another represent branched or unbranched alkyl, aryl or alkenyl radicals, where X and Y are not identical and in each case either one Oxyethylene group or an oxypropylene group and n and m independently represent numbers, the sum of which is greater than 100

The PEG-150 distearate, PEG 800 distearate, PEG-800 Chol ₂ and the PEG-150 dioleate are particularly advantageous. The PEG-300 pentaerythrityl tetraisostearate, the PEG-120 methyl glucose dioleate, the PEG-160 sorbitan triisostearate, the PEG-450 sorbitol hexaisostearate and the PEG-230 glyceryl triisostearate can also be used advantageously as thickeners. PEG-200 glyceryl palmitate is also suitable. The thickener from Südchemie with the designation Purethix 1442 (polyether-1) is also advantageous. It is also possible to use polyurethane thickeners, such as Rheolate 204, 205, 208 (Rheox company) or modified cosmetic variants or DW 1206B from Rhom & Haas or Serad Fx 1010, 1035 from Hüls.

It is also advantageous to use mixtures of the polymers described above, for example from PEG 800 distearate and PEG-800 Chol ₂ .

Celluloses are also particularly advantageous, for example Hydroxypropylmethylcellulose (HPMC), which are not to be regarded as crosslinkers use. Combinations of HPMC and the advance described crosslinkers can be used.

A slightly modified way of forming inventive Microemulsion gels consist of the oil droplets using hydrophobically modified, immobilize synthetic or natural polymers. Such polymers will sometimes referred to as associative thickener.

Accordingly, it is also advantageous, in particular if the thickener (s) is selected should be from the group of associative thickeners, hydrophobically substituted To choose polysaccharide derivatives, for example hydrophobically substituted cellulose ethers, Hydrophobically substituted starches, alginates, glucans, chitins, dextrans, caseinates, Pectins, proteins and gums, also polyurethanes, polyacrylamides, Polyvinyl alcohols, polyacrylates, water-soluble silicone polymers and the like.

For example, cetylhydroxyethyl cellulose should be used. It is also To use hydroxypropylmethyl cellulose very preferably. To improve the Foam structure, foam quality and amount of foam are also polyethylene glycols with long PEG units are particularly preferred, for example PEG-14 M, PEG-45 M from Amerchol and Oxethal VD 92 (glyceryl-90 isostearate + Laureth-2) from Zschimmer and Black.

• 1. Quaternäre Derivate von Celluloseethern
  Bevorzugt ist beispielsweise Polyquaternium 10, Polyquaternium 24
• 2. Quaternäre Derivate von Gummen
  Bevorzugt ist beispielsweise Guar Hydroxypropyltrimonium chlorid und Hydroxypropyltrimonium hydroxypropyl guar
• 3. Homopolymere und Copolymere von Dimethyl diallyammonium Chloride (DMDAAC)
  Bevorzugt ist beispielsweise Polyquaternium 4 und 6 und 7
• 4. Homopolymere und Copolymere von Methacrylamidopropyl trimethyl ammonium chlorid (MAPTAC)
  Bevorzugt ist beispielsweise Polyquaternium 28 und Polymethacrylamidopropyltrimonium chlorid
• 5. Homopolymere und Copolymere von Acrylamidopropyl trimethyl ammonium chlorid (APTAC)
• 6. Homopolymere und Copolymere von Methacryloyloxy ethyl trimethyl ammonium chlorid (METAC)
  Bevorzugt ist beispielsweise Polyquaternium 32 und Polyquaternium 37
• 7. Homopolymere und Copolymere von Acryloyloxy ethyl trimethyl ammonium chlorid (AETAC)
  Bevorzugt ist beispielsweise Polyquaternium 33
• 8. Homopolymere und Copolymere von Methacryloyloxy ethyl trimethyl ammonium methyl sulfat (METAMS)
  Bevorzugt ist beispielsweise Polyquaternium 5 und Polyquaternium 11 und Polyquaternium 14 und Polyquaternium 15 und Polyquaternium 36 und Polyquaternium 45
• 9. Homopolymere und Copolymere von Vinylpyrrolidon
  Bevorzugt ist beispielsweise Luviquat 905
• 10. Kationische Polysaccharide basierend auf Hydroxyalkylcellulosen, Stärken, Hydroxyalkylstärken, Polymere basierend auf Arabinose Monomeren, Polymere abgeleitet von der Xylose, Fucose, Fructose, Galacturonsäure und Glucuronsäure, Galactosamin und Glucosamin, Acetylglucosamin, Galactose, Mannose
  Bevorzugt sind beispielsweise Hydroxypropyl trimethyl ammoniumchlorid Derivate von Stärke, die von Korn, Kartoffel, Rice, Tapioaca, Weizen und dergleichen sein kann
• 11. Ammonium substituierte Polydimethylsiloxane
  Bevorzugt sind beispielsweise Trimethylsilylamodimethicon (Dow Corning Q2- 8220), Copolymere von Polydimethylsiloxan und Poly C2-C3 Alkylenether (Dow Corning 190, Dow Corning 2-5324, Dow Corning Q2-5220), Abil-Quat 3270
• 12. PVP
• 13. Polyethylenimine
  Bevorzugt ist beispielsweise Lupasol FG (BASF), Lupasol G-35 (BASF), Lupasol P (BASF)
• 14. Chitosan.

Cationic polymers can also be added as thickeners. These improve the feeling on the skin and can advantageously influence the foaming behavior of the formulations according to the invention. The cationic polymers can be selected from:

• 1. Quaternary derivatives of cellulose ethers
  For example, polyquaternium 10 and polyquaternium 24 are preferred
• 2. Quaternary derivatives of gums
  For example, guar hydroxypropyltrimonium chloride and hydroxypropyltrimonium hydroxypropyl guar are preferred
• 3. Homopolymers and copolymers of dimethyl diallyammonium chloride (DMDAAC)
  For example, polyquaternium 4 and 6 and 7 is preferred
• 4.Homopolymers and copolymers of methacrylamidopropyl trimethyl ammonium chloride (MAPTAC)
  For example, polyquaternium 28 and polymethacrylamidopropyltrimonium chloride are preferred
• 5. Homopolymers and copolymers of acrylamidopropyl trimethyl ammonium chloride (APTAC)
• 6. Homopolymers and copolymers of methacryloyloxy ethyl trimethyl ammonium chloride (METAC)
  For example, polyquaternium 32 and polyquaternium 37 are preferred
• 7. Homopolymers and copolymers of acryloyloxy ethyl trimethyl ammonium chloride (AETAC)
  For example, polyquaternium 33 is preferred
• 8.Homopolymers and copolymers of methacryloyloxy ethyl trimethyl ammonium methyl sulfate (METAMS)
  For example, polyquaternium 5 and polyquaternium 11 and polyquaternium 14 and polyquaternium 15 and polyquaternium 36 and polyquaternium 45 are preferred
• 9. Homopolymers and copolymers of vinyl pyrrolidone
  For example, Luviquat 905 is preferred
• 10. Cationic polysaccharides based on hydroxyalkyl celluloses, starches, hydroxyalkyl starches, polymers based on arabinose monomers, polymers derived from xylose, fucose, fructose, galacturonic acid and glucuronic acid, galactosamine and glucosamine, acetylglucosamine, galactose, mannose
  Preferred are, for example, hydroxypropyl trimethyl ammonium chloride derivatives of starch, which can be from grain, potato, rice, tapioaca, wheat and the like
• 11. Ammonium substituted polydimethylsiloxanes
  For example, trimethylsilylamodimethicone (Dow Corning Q2- 8220), copolymers of polydimethylsiloxane and poly C2-C3 alkylene ether (Dow Corning 190, Dow Corning 2-5324, Dow Corning Q2-5220), Abil-Quat 3270 are preferred
• 12. PVP
• 13. Polyethyleneimines
  Preferred is, for example, Lupasol FG (BASF), Lupasol G-35 (BASF), Lupasol P (BASF)
• 14. Chitosan.

It may also be advantageous if the one or more according to the invention used thickeners on physiological effectiveness in the sense of a cosmetic or has pharmaceutical effects. For example, the in German Offenlegungsschrift 43 44 661 disclosed biosurfactant esters can be used advantageously for the purposes of the present invention.

Furthermore, oils with different polarity, molecular weight and structure be used. The oil component or all of the oil components of the Preparation according to the invention is preferably selected from the group of the esters saturated and / or unsaturated, branched and / or unbranched Alkanecarboxylic acids or hydroxyalkanecarboxylic acids with a chain length of 1 to 44 carbon atoms and saturated and / or unsaturated, branched and / or unbranched Alcohols with a chain length of 1 to 44 carbon atoms, from the group of the esters aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols with a chain length of 1 to 30 carbon atoms if the Oil component or all of the oil components at room temperature Represent liquid. Such ester oils can advantageously be chosen from the Group isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n- Butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate, Isononyl isononanoate, 2-ethylhexyl palmitate, 2-ethylhexyl laurate, 2-hexyldecyl stearate, 2-octyldodecyl palmitate, oleyl oleate, olerlerucate, erucyl oleate, erucylerucate and synthetic, semi-synthetic and natural mixtures of such esters, e.g. B. Jojoba oil. For example, ester oils have become more foaming especially for the production Proven preparations. Cetearyl isononanoate is particularly advantageous, Isopropyl myristate, isopropyl palmitate, ethylhexyl cocoate, 2-ethylhexyl aurate, 2- Ethyl hexypalmitate, decyl oleate, octyl isostearate, isotridecyl isononaoate or else corresponding ester oil mixtures.

The oil phase can advantageously be selected from the group of branched and unbranched hydrocarbons, the silicone oils, lanolins, the adipic acid ester, the Butylene glycol diesters, the dialkyl ethers or carbonates, the group of the saturated or unsaturated, branched alcohols, and fatty acid triglycerides, especially the Triglycerol esters saturated and / or unsaturated, branched and / or unbranched Alkane carboxylic acids with a chain length of 8 to 24, in particular 12-18 C atoms. The fatty acid triglycerides can, for example, advantageously be selected from the Group of synthetic, semi-synthetic and natural oils, e.g. B. olive oil, Sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, palm kernel oil Macadamia oil, evening primrose oil and the like.

The oil phase can also advantageously have a cyclic or linear content Have silicone oils or consist entirely of such oils, although preferred will, in addition to the silicone oil or oils, an additional content of others To use oil phase components.

Cyclomethicone (octamethylcyclotetrasiloxane) is advantageous as according to the invention using silicone oil. But other silicone oils are also advantageous in To use the sense of the present invention, for example Hexamethylcyclotrisiloxane, polydimethylsiloxane, poly (methylphenylsiloxane).

Dicapylyl carbonate, dicaprylyl ether, paraffin oil, coco, for example, are very advantageous Caprylate / caprate, caprylic / capric triglyceride, cyclomethicone, dimethicone, Octyldodecanol. Oil mixtures can also be used very advantageously such as paraffin oil / dicaprylyether, paraffin oil / cococaprylate caprate.

Advantageous oil components are also e.g. B. butyl octyl salicylate (for example available under the trade name Hallbrite BHB from CP Hall), Hexadecyl benzoate and butyl octyl benzoate and mixtures thereof (Hallstar AB) and / or Diethylhexyl naphthalate (Hallbrite TQ).

For example, dialkyl ethers, dialkyl carbonates, mineral oils have been produced proven more foaming preparations. Are particularly advantageous Dicaprylyl ether, dicaprylyl carbonate, paraffin oil, hydrogenated polydecene, petroleum jelly or corresponding mixtures of the lipids described above.

The oil components can advantageously be present in a content of 1 to 50% by weight on the total preparation, about 1 to 40% by weight are preferred.

It was also astonishing that very high concentrations of oils and lipids (1-15% by weight) with a total surfactant content of 15% by weight (active) and W / O emulsifier content from 0.0 to 10% by weight can be used. Furthermore, the total surfactant content (less than 15% by weight) can also be lower without the microemulsion structure (e.g. transparency if water-clear preparations are sought) get lost.

Through the use of waxes (ester waxes, triglyceride waxes, ethoxylated Waxes etc.) in the oil phase or as an oil phase, the adhesion of the Improve substances again.

It is preferred if the wax component or all of the Wax components are selected from the group consisting of saturated and / or esters unsaturated, branched and / or unbranched alkane carboxylic acids or Hydroxycarboxylic acids with a chain length of 1 to 80 carbon atoms and saturated and / or unsaturated, branched and / or unbranched alcohols Chain length from 1 to 80 carbon atoms, from the group of esters from aromatic Carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols with a chain length of 1 to 80 carbon atoms provided the wax component or the entirety of the wax components at room temperature is a solid represent natural waxes, the diesters of polyols and C10-C80 fatty acids, the ethoxylated waxes, the triglyceride waxes, the C16-C60 fatty acids and / or C16-C80 fatty alcohols, the mineral oil waxes.

The wax components from the group of the C _{16-36 alkyl} stearates, the C _10-40 alkyl stearates, the C _20-40 alkyl isostearates, the C _20-40 dialkyl dimerates, the C _18-38 alkyl hydroxystearoyl stearates, the C20- 40-dialkyl dimerate, the C _20-40 alkylucate can be selected, furthermore C _30-50 alkyl beeswax, cetyl palmitate, methyl palmitate, cetearyl behenate, octacosanyl stearate. Silicone waxes such as stearyltrimethylsilane / stearyl alcohol may also be advantageous.

• 1. gesättigten und/oder ungesättigten, verzweigten und/oder unverzweigten Mono- und/oder Dicarbonsäure mit 10 bis 50 Kohlenstoffatomen, bevorzugt 15-45 Kohlenstoffatomen und
• 2. Glycerin

darstellen. Dabei können Mono-, Di- und Triglyceride vorteilhaft sein. Also advantageous in the sense of the present invention are ester waxes, the esters of

• 1. saturated and / or unsaturated, branched and / or unbranched mono- and / or dicarboxylic acid having 10 to 50 carbon atoms, preferably 15-45 carbon atoms and
• 2. Glycerin

represent. Mono-, di- and triglycerides can be advantageous here.

The glycerides listed below are particularly advantageous:

It is particularly preferred to choose the wax components from the group of Triglyceride waxes like C18-38 triglyceride or tribehenin to choose.

It has also been found that ethoxylated waxes such as PEG-8 Beeswax, PEG 6 sorbitan beeswax, PEG-2 hydrogenated castoroil, PEG-12 Carnauba waxes are beneficial.

In particular, moisturizers such as glycerol, chitosan, fucogel, lactic acid, Propylene glycol, sorbitol, polyethylene glycol, dipropylene glycol, butylene glycol, mannitol, Sodium pyrolidone carboxylic acid, glycine, hyaluronic acid and its salts, urea, Sodium and potassium salts are easier to bind to the skin. Through the Use of waxes (ester waxes, triglyceride waxes, ethoxylated waxes, etc.) in the oil phase or as an oil phase, the adherence of the active ingredients and Improve the moisturizer again.

Furthermore, light protection filters can also be used much more easily, so that Shower-on products result, d. H. the user receives directly during the Showering a protective protection against sun rays for skin and hair. The Experts know how difficult sun protection filters are in shower products containing surfactants can be formulated while maintaining transparency.

The microemulsion according to the invention is characterized in that for the production the microemulsions according to the invention or their gels contain a large number of W / O Emulsifiers can be used.

According to the invention, the W / O emulsifier (s) can be selected from the Group of fatty alcohols with 8-30 carbon atoms, saturated monoglycerol esters and / or unsaturated, branched and / or unbranched alkane carboxylic acids or Hydroxycarboxylic acids with a chain length of 8-24, in particular 12-18, carbon atoms, Diglycerol esters saturated and / or unsaturated, branched and / or unbranched Alkane carboxylic acids or hydroxy carboxylic acids with a chain length of 8-24, in particular 12-18 C atoms, triglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkane carboxylic acids or hydroxy carboxylic acids Chain length of 8-24, especially 12-18 C atoms, saturated polyglycerol esters and / or unsaturated, branched and / or unbranched alkane carboxylic acids or Hydroxycarboxylic acids with a chain length of 8-24, especially 12-18 carbon atoms with up to 10 glycerol units, monoglycerol ethers saturated and / or unsaturated, branched and / or unbranched alcohols with a chain length of 8-24, in particular 12-18 C atoms, diglycerol ethers saturated and / or unsaturated, branched and / or unbranched alcohols with a chain length of 8-24, in particular 12-18 C- Atoms, triglycerol ethers saturated and / or unsaturated, branched and / or unbranched alcohols with a chain length of 8-24, in particular 12-18, carbon atoms, Polyglycerol ethers saturated and / or unsaturated, branched and / or unbranched alcohols with a chain length of 8-24, in particular 12-18 C atoms with up to 10 glycerol units, propylene glycol esters saturated and / or unsaturated, branched and / or unbranched alkane carboxylic acids or hydroxycarboxylic acids Chain length of 8-24, especially 12-18 C atoms, sorbitan esters more saturated and / or unsaturated, branched and / or unbranched alkane carboxylic acids or Hydroxycarboxylic acids with a chain length of 8-24, in particular 12-18, carbon atoms, Sorbitan esters of polyols, especially glycerol, pentaerythritylester saturated and / or unsaturated, branched and / or unbranched alkane carboxylic acids or hydroxycarboxylic acids with a chain length of 8-24, in particular 12-18 C- Atoms, methyl glucose esters saturated and / or unsaturated, branched and / or unbranched alkane carboxylic acids or hydroxycarboxylic acids with a chain length of 8-24, especially 12-18 carbon atoms, polyglycerol methyl glucose ester saturated and / or unsaturated, branched and / or unbranched alkane carboxylic acids or Hydroxycarboxylic acids with a chain length of 8-24, in particular 12-18, carbon atoms, Cetyl dimethicone copolyols, alkyl methicone copolyols, alkyl diemethicone ethoxy Glucoside, glyceryl fatty acid citrate.

It can be advantageous according to the invention that the types of W / O emulsifiers are additionally polyethoxylated and / or polypropoxylated, or that other polyethoxylated and / or polypropoxylated products are also used, for example polyethoxylated hydrogenated or non-hydrogenated castor oil, ethoxylated cholesterol, ethoxylated fatty alcohols such as steareth-2, ethoxylated Fatty acids, ethoxylated dicarboxylic acids, ethoxylated waxes such as PEG (-6, -8, -12, - 20) Beeswax, PEG (-6, -8, -20 sorbitan beeswax), ethoylated Carnauba wax (PEG-12 carnauba wax).

Particularly advantageous W / O emulsifiers are glyceryl alcoholate, glyceryl monostearate, Glyceryl monoisostearate, glyceryl linoleate, glyceryl monooleate, diglyceryl monostearate, Diglyceryl monoisostearate, diglyceryl diisostearate, propylene glycol monostearate, Propylene glycol monoisostearate, propylene glycol diisostearate, sorbitan monoisostearate, Sucrose distearate, cetyl alcohol, stearyl alcohol, arachidyl alcohol, behenyl alcohol, Isobehenyl alcohol, 2-ethylhexylglycerol ether, selachyl alcohol, chimyl alcohol, Polyethylene glycol (2) stearyl ether (steareth-2), glyceryl monolaurate, glyceryl monocaprinate, Glyceryl monocaprylate, glyceryl sorbitan stearate polyglyceryl-4 isostearate, polyglyceryl-2- sesquiisostearate, PEG-7 hydrogenated castor oil, PEG-40 sorbitan perisostearate, Isostearyl diglyceryl succinate, PEG-5 cholesteryl ether, triglycerol diisostearate, PEG-30 Dipolyhydroxystearate, decaglyceryl heptaoleate, polyglyceryl-3-diisostearate, PEG-8- Distearate, diglycerol dipolyhydroxystearate.

The emulsions according to the invention can furthermore contain stabilizers. Preferred stabilizers are the PEG-45 / dodecyl glycol copolymer, PEG-22 / dodecyl glycol copolymer and / or methoxy-PEG-22-dodecyl glycol copolymer. The Stabilizer or stabilizers are advantageously in concentrations of 0.01-25% by weight before, although it is possible and advantageous, the content of To keep stabilizers low, about up to 5 wt .-%, each based on the total weight of the Composition. It is particularly advantageous to choose stabilizers when preparations according to the invention have a high destabilizing content Should contain substances. If the content of destabilizing substances is low, you can do without the stabilizer.

The W / O emulsifier used according to the invention or that according to the invention W / O emulsifiers used are or are advantageously in concentrations of 0.1-25% by weight before, although it is possible and advantageous, the content of emulsifiers to keep low, about up to 5 wt .-%, each based on the total weight of the Composition.

In addition, the microemulsions according to the invention can be dyes and / or Pigments included. Pigments can be used if they are nanodiperged (10-100 nm) are present, dyes make the product, for example, blue transparent. The Dyes and pigments can be found in the corresponding positive list of Cosmetics regulation or the EC list of cosmetic colorants can be selected. In most cases, they are made with the dyes approved for food identical. Pigments can be of organic and inorganic origin, such as for example organic of the azo type, indigoids, triphenylmethane-like, Anthraquinones, and xanthine dyes, which as D&C and FD&C blues, browns, greens, oranges, reds, yellows are known. Inorganic pigments consist of insoluble ones Salting certified dyes called lakes or iron oxides. For example, barium lakes, calcium lakes, aluminum lakes, titanium dioxide, mica and iron oxides are used. As Al salts z. B. Red 3 Aluminum Lake, Red 21 Aluminum Lake, Red 27 Aluminum Lake, Red 28 Aluminum Lake, Red 33 Aluminum Lake, Yellow 5 Aluminum Lake, Yellow 6 Aluminum Lake, Yellow 10 Aluminum Lake, Orange 5 Aluminum Lake, Blue 1 Aluminum Lake and combinations can be used.

As iron oxides or hydrated oxides such. B. cosmetic yellow oxide C22-8073 (Sunchemical) cosmetic oxide MC 33-120 (Sunchemical), cosmetic brown oxide C33- 115 (Nordmann & Rassmann), cosmetic russet oxide C33-8075 (Sunchemical) and possibly advantageous. The aluminosilicate is ultramarine blue (Les colorants Wacker) used.

Pearlescent pigments can also be incorporated into the emulsions according to the invention incorporated. These are, for example, from the companies Costenoble (Cloisonne type, Flamenco type, Low Luster type), Merck (Colorona types, Microna type, Timiron type, Colorona, Ronasphere), Les Colornats Wacker (Covapure, Vert oxyde de Chrome), Cadre (Colorona, Sicopearl), BASF (Sicopearl, Sicovit), Rona (Colorona) are known. As Timiron Silk Gold, for example, has proven to be particularly advantageous pearlescent pigment and Colorona Red Gold proven.

Advantageous color pigments are also titanium dioxide, mica, iron oxides (for example Fe ₂ O ₃ , Fe ₃ O ₄ , FeO (OH)) and / or tin oxide. Advantageous dyes are, for example, carmine, Berlin blue, chrome oxide green, ultramarine blue and / or manganese violet. It is particularly advantageous to choose the dyes and / or color pigments from the list below. (The fabrics are sorted by their Color Index Number.)

The dyes and pigments can be present either individually or in a mixture and be mutually coated with one another, with different Coating thicknesses are generally caused by different color effects.

The list of dyes and pigments mentioned in the invention Emulsions that can be used should of course not be limiting.

Emulsions according to the invention can also contain powder substances. As powder substances bismuth oxychloride, titanized mica, silicon dioxide (fumed silica), spherical silicon dioxide beads, polymethyl methacrylate beads, micronized Teflon, boron nitride, acrylate polymers, aluminum silicate, aluminum starch octenyl succinate, Bentonite, calcium silicate, cellulose, chalk, corn starch, glyceryl starch, hectorite, hydrated silica, kaolin, magnesium hydroxides, magnesium oxide, magnesium silicates, Magnesium trisilicate, maltodextrin, montmorillonite, microcrystalline cellulose, rice starch, Silica, talc, mica, titanium dioxide, zinc laurate, zinc myristate, zinc neodecanoate, Zinc rosinate, zinc stearate, polyethylene, aluminum oxide, attapulgite, calcium carbonate, Calcium silicate, dextran, kaolin, nylon, silica silylate, silk powder, serecite, tin oxide, Titanium hydroxide, trimagnesium phosphate, walnut shell powder or any Mixtures are used.

In formulations according to the invention, large amounts of hydrophilic as well as hydrophobic active substances or combinations of hydrophilic and hydrophobic active substances can be incorporated into the formulations. Such active substances which are advantageous according to the invention are, for example, acetylsalicylic acid, azulene, ascorbic acid, vitamin B ₁ , vitamin B _12, vitamin D ₁ , but also bisabolol, unsaturated fatty acids, in particular the essential fatty acids (often also called vitamin F), in particular γ-linolenic acid, Oleic acid, eicosapentaenoic acid, docosahexaenoic acid, camphor, extracts or other products of plant and animal origin, e.g. B. evening primrose oil, borage oil or currant seed oil, fish oils, cod liver oil but also ceramides and ceramide-like compounds and so on.

In addition, care ingredients can be incorporated that do not affect the restrict fat-soluble active ingredients, but also from the group of water-soluble Active ingredients can be selected, for example vitamins and the like.

An amazing property of the preparations according to the invention is that they are very good vehicles for cosmetic or dermatological agents in the skin, preferred active ingredients are antioxidants which protect the skin from being oxidative Can protect stress.

The preparations therefore advantageously contain one or more antioxidants. As Cheap, but optional, antioxidants can all be used for cosmetic and / or dermatological applications suitable or customary Antioxidants are used. It is advantageous to have antioxidants as the only ones Active ingredient class to use, for example, when a cosmetic or Dermatological application is in the foreground like combating the oxidative Stress on the skin. But it is also cheap, the invention W / O emulsion sticks containing one or more antioxidants if the preparations are to serve another purpose, e.g. B. as deodorants or Sunscreens.

The antioxidants are particularly advantageously selected from the group consisting of amino acids (e.g. glycine, histidine, tyrosine, tryptophan) and their derivatives, imidazoles (e.g. urocanic acid) and their derivatives, peptides such as D, L-carnosine, D-carnosine, L-carnosine and their derivatives (e.g. anserine), carotenoids, carotenes (e.g. α-carotene, β-carotene, lycopene) and their derivatives, lipoic acid and their derivatives (e.g. dihydroliponic acid ), Aurothioglucose, propylthiouracil and other thiols (e.g. thioglycerin, thiosorbitol, thioglycolic acid, thioredoxin, glutathione, cysteine, cystine, cystamine and their glycosyl, N-acetyl, methyl, ethyl, propyl, amyl, Butyl and lauryl, palmitoyl, oleyl, γ-linoleyl, cholesteryl and glyceryl esters) and their salts, dilaurylthiodipropionate, distearylthiodipropionate, thiodipropionic acid and their derivatives (esters, ethers, peptides, lipids, nucleotides, nucleosides and salts) and Sulfoximine compounds (e.g. buthionine sulfoximines, homocysteine sulf oximine, buthionine sulfones, pentate, hexa-, heptahionine sulfoximine) in very low tolerable dosages (e.g. B. pmol to µmol / kg), further (metal) chelators (e.g. α-hydroxy fatty acids, palmitic acid, phytic acid, lactoferrin), α-hydroxy acids (e.g. citric acid, lactic acid, malic acid), humic acid, bile acid, Bile extracts, bilirubin, biliverdin, EDTA, EGTA and their derivatives, unsaturated fatty acids and their derivatives (e.g. gamma-linolenic acid, linoleic acid, oleic acid), folic acid and their derivatives, ubiquinone and ubiquinol their derivatives, vitamin C and derivatives (e.g. As ascorbyl palmitates, Mg ascorbyl phosphates, ascorbylacetates), isoascorbic acid and its derivatives, tocopherols and derivatives (e.g. vitamin E acetate), vitamin A and derivatives (vitamin A palmitate) and coniferyl benzoate of benzoin, rutinic acid and its derivatives, Ferulic acid and its derivatives, butylated hydroxytoluene, butylated hydroxyanisole, nordihydroguajak resin acid, nordihydroguajaretic acid, trihydroxybutyrophenone, uric acid and its derivatives, mannose and its derivatives, zinc and its derivatives (e.g. ZnO, ZnSO ₄ ) selenium and its derivatives (e.g. B. selenomethionine), stilbenes and their derivatives (for example stilbene oxide, trans-stilbene oxide) and the derivatives suitable according to the invention (salts, esters, ethers, sugars, nucleotides, nucleosides, peptides and lipids) of these active substances.

The amount of the antioxidants used in the preparations is preferably 0.001 to 30% by weight, particularly preferably 0.001-20% by weight, in particular 0.001-10% by weight, based on the total weight of the preparation.

If vitamin E and / or its derivatives are the antioxidant (s) it is advantageous to adjust their respective concentrations from the range of 0.001-10% by weight, based on the total weight of the formulation.

If vitamin A, or vitamin A derivatives, or carotenes or their derivatives, the or the antioxidants are advantageous, their respective concentrations from the Range of 0.001-10% by weight based on the total weight of the formulation choose.

According to the invention, active substances can also be selected very advantageously from the group of lipophilic active substances, in particular from the following group:
Acetylsalicylic acid, atropine, azulene, hydrocortisone and its derivatives, e.g. B. hydrocortisone 17-valerate, vitamins, e.g. B. ascorbic acid and its derivatives, vitamins of the B and D series, very cheap vitamin B ₁ , vitamin B _12, vitamin D ₁ , but also bisabolol, unsaturated fatty acids, especially the essential fatty acids (often called vitamin F) , in particular γ-linolenic acid, oleic acid, eicosapentaenoic acid, docosahexaenoic acid and their derivatives, chloramphenicol, caffeine, prostaglandins, thymol, camphor, extracts or other products of plant and animal origin, e.g. B. evening primrose oil, borage oil or currant seed oil, fish oils, cod liver oil but also ceramides and ceramide-like compounds and so on.

It is also advantageous to add the active ingredients from the group of refatting substances choose, for example Purcellinöl®, Eucerit® and Neocerit®.

The active ingredient (s) are particularly advantageously selected from the group the NO synthase inhibitor, especially when the preparations according to the invention for the treatment and prophylaxis of the symptoms of intrinsic and / or extrinsic skin aging as well as for the treatment and prophylaxis of harmful Effects of ultraviolet radiation on the skin are said to serve. Preferred NO The inhibitor of synthase is nitroarginine.

The active ingredient (s) are also advantageously selected from the group consisting of Catechins and bile esters of catechins and aqueous or organic Extracts from plants or parts of plants which contain catechins or bile esters of catechins, such as the leaves of the Plant family Theaceae, especially the species Camellia sinensis (green tea). Their typical ingredients (such as polyphenols or Catechins, caffeine, vitamins, sugar, minerals, amino acids, lipids).

Catechins are a group of compounds known as hydrogenated flavones or Anthocyanidins are to be understood and derivatives of "catechins" (catechol, 3,3 ', 4', 5,7- Flavanpentaol, 2- (3,4-dihydroxyphenyl) -chroman-3,5,7-triol). Also Epicatechin ((2R, 3R) -3,3 ', 4', 5,7-flavanpentaol) is an advantageous active ingredient in the sense of the present invention.

Plant extracts containing catechins are also advantageous, in particular extracts of green tea, such as. B. Extracts from leaves of plants Species Camellia spec., Especially Camellia sinenis, C. assamica, C. taliensis or C. irrawadiensis and crosses of these with, for example Camellia japonica.

Preferred active ingredients are also polyphenols or catechins from the group (-) - Catechin, (+) - catechin, (-) - catechin gallate, (-) - gallocatechin gallate, (+) - epicatechin, (-) - Epicatechin, (-) - epicatechin gallate, (-) - epigallocatechin, (-) - epigallocatechin gallate.

Flavon and its derivatives (often also collectively called "flavones") are also advantageous active substances in the sense of the present invention. They are characterized by the following basic structure (substitution positions specified):

Some of the more important flavones, which can also preferably be used in preparations according to the invention, are listed in the table below:

In nature, flavones usually occur in glycosidated form.

According to the invention, the flavonoids are preferably selected from the group of substances of the generic structural formula


where Z ₁ to Z ₇ are selected independently of one another from the group H, OH, alkoxy and hydroxyalkoxy, where the alkoxy or hydroxyalkoxy groups can be branched and unbranched and can have 1 to 18 carbon atoms, and wherein Gly is selected from the group of mono- and oligoglycoside residues.

According to the invention, the flavonoids can also be advantageously selected from the group of substances of the generic structural formula


where Z ₁ to Z _{6 are} independently selected from the group H, OH, alkoxy and hydroxyalkoxy, where the alkoxy or hydroxyalkoxy groups can be branched and unbranched and can have 1 to 18 carbon atoms, and wherein Gly is selected from the group of mono- and oligoglycoside residues.

Such structures can preferably be selected from the group of substances of the generic structural formula


where Gly ₁ , Gly ₂ and Gly ₃ independently of one another represent monoglycoside residues or. Gly ₂ or Gly ₃ can also individually or together represent saturations by hydrogen atoms.

Gly ₁ , Gly ₂ and Gly ₃ are preferably selected independently of one another from the group of the hexosyl radicals, in particular the rhamnosyl radicals and glucosyl radicals. However, other hexosyl radicals, for example allosyl, altrosyl, galactosyl, gulosyl, idosyl, mannosyl and talosyl, may also be used advantageously. It can also be advantageous according to the invention to use pentosyl residues.

Z ₁ to Z ₅ are advantageously selected independently of one another from the group H, OH, methoxy, ethoxy and 2-hydroxyethoxy, and the flavone glycosides have the structure

The flavone glycosides according to the invention from the group which are represented by the following structure are particularly advantageous:


where Gly ₁ , Gly ₂ and Gly ₃ independently of one another represent monoglycoside residues or. Gly ₂ or Gly ₃ can also individually or together represent saturations by hydrogen atoms.

Gly ₁ , Gly ₂ and Gly ₃ are preferably selected independently of one another from the group of the hexosyl radicals, in particular the rhamnosyl radicals and glucosyl radicals. However, other hexosyl radicals, for example allosyl, altrosyl, galactosyl, gulosyl, idosyl, mannosyl and talosyl, may also be used advantageously. It can also be advantageous according to the invention to use pentosyl residues.

For the purposes of the present invention, this or that is particularly advantageous Flavone glycosides to be selected from the group α-glucosylrutin, α-glucosylmyricetin, α-glucosylisoquercitrin, α-glucosylisoquercetin and α-glucosylquercitrin. According to the invention α-glucosylrutin is particularly preferred.

Naringin (aurantiin, Naringenin-7-rhamnoglucoside), hesperidin (3 ', 5,7-trihydroxy-4'-methoxyflavanon-7-rutinoside, hesperidoside, Hesperetin-7-O-rutinoside). Rutin (3,3 ', 4', 5,7-pentahydroxyflyvon-3-rutinosid, quercetin-3 rutinoside, sophorin, birutan, rutabion, taurutin, phytomelin, melin), troxerutin (3,5-dihydroxy-3 ', 4', 7-tris (2-hydroxyethoxy) flavone-3- (6-O- (6-deoxy-α-L-mannopyranosyl) -β- D-glucopyranoside)), monoxerutin (3,3 ', 4', 5-tetrahydroxy-7- (2-hydroxyethoxy) -flavon-3- (6-O- (6-deoxy-α-L-mannopyranosyl) -β-D-glucopyranoside)), dihydrorobinetin (3,3 ', 4', 5 ', 7-pentahydroxyflavanone), taxifolin (3,3', 4 ', 5,7-pentahydroxyflavanone), Eriodictyol-7-glucoside (3 ', 4', 5,7-tetrahydroxyflavanone-7-glucoside), flavanomareïn (3 ', 4', 7,8-tetrahydroxyflavanone-7-glucoside) and isoquercetin (3,3 ', 4', 5,7-pentahydroxyflavanone-3- (β-D-glucopyranoside).

It is also advantageous to use the active ingredient (s) from the group of ubiquinones and To choose plastoquinones.

Ubiquinones are characterized by the structural formula


and represent the most widespread and thus the best studied bioquinones. Depending on the number of isoprene units linked in the side chain, ubiquinones are called as Q-1, Q-2, Q-3 etc. or according to the number of C atoms U-5, U-10, U- 15 and so on. They preferably occur with certain chain lengths, e.g. B. in some microorganisms and yeasts with n = 6. In most mammals, including humans, Q10 predominates.

Coenzyme Q10, which is characterized by the following structural formula, is particularly advantageous:

Plastoquinones have the general structural formula


on. Plastoquinones differ in the number n of isoprene residues and are designated accordingly, e.g. B. PQ-9 (n = 9). There are also other plastoquinones with different substituents on the quinone ring.

Creatine and / or creatine derivatives are also preferred active substances for the purposes of the present invention. Creatine is characterized by the following structure:

Preferred derivatives are creatine phosphate and creatine sulfate, creatine acetate, Creatine ascorbate and that on the carboxyl group with mono- or polyfunctional alcohols esterified derivatives.

Another advantageous active ingredient is L-carnitine [3-hydroxy-4- (trimethylammonio) butyric acid betaine]. Also acyl-carnitine, which is selected from the group of substances of the following general structural formula


where R is selected from the group of branched and unbranched alkyl radicals having up to 10 carbon atoms are advantageous active ingredients in the sense of the present invention. Propionylcarnitine and in particular acetylcarnitine are preferred. Both entantiomers (D- and L-form) can be used advantageously for the purposes of the present invention. It may also be advantageous to use any mixture of enantiomers, for example a racemate of D and L form.

Other advantageous active ingredients are sericoside, pyridoxol, aminoguadin, phytochelatin, Isoflavones (genistein, daidzein, daidzin, glycitin), niacin, tyrosine sulfate, dioic acid, Adenosine, pyridoxine, arginine, vitamin K, biotin and flavorings, sericoside as well Active substance combinations of the active substances mentioned.

The list of active substances or combinations of active substances mentioned in the Preparations according to the invention can of course not be used be limiting. The active ingredients can be individual or in any combination can be used together.

It is optionally possible and advantageous to prepare the preparations according to the invention to be used as the basis for pharmaceutical formulations. Mutatis mutandis Corresponding requirements apply to the formulation of medical Preparations. The transitions between pure cosmetics and pure pharmaceuticals are included fluently. According to the invention, all of them are basically pharmaceutical active ingredients Active substance classes are suitable, lipophilic active substances being preferred. Examples are: Antihistamines, anti-inflammatory drugs, antibiotics, antifungals that promote blood circulation Active ingredients, keratolytics, antihistamines, anti-inflammatory drugs, antibiotics, antifungals, the Active substances promoting blood circulation, keratolytics, hormones, steroids, vitamins, Hormones, steroids, vitamins, etc.

It is optionally possible and advantageous to use the preparations according to the invention Incorporate repellents. Particularly advantageous repellent active ingredients in the sense of In the present invention, the above-mentioned active ingredients are N, N-diethyl-3- methylbenzamide, 3- (N-n-butyl-N-acetylamino) propionic acid ethyl ester, 1- Piperidinecarboxylic acid 2- (2-hydroxyethyl) -1-methylpropyl ester and dimethyl phthalate.

The invention also relates to the use of oil-containing and also foaming Microemulsions as cleaning products, in particular as shower gels, shampoos, Cleansing preparations, hand washing products, bath preparations, make-up Remover or shaving products. The microemulsions can be used as an impregnation medium for Serve cloths, fabrics that are applied wet or dry by the consumer or the microemulsions can be filled into a pumpoamer and applied become.

The cleaning products according to the invention are used in the Cosmetics usual way on the skin and / or hair in sufficient quantities applied, if necessary distributed, massaged in and finally washed off.

The following examples are intended to illustrate the present invention without it limit. All quantities, parts and percentages are, if not otherwise stated, on the weight and the total amount or on the Total weight of the preparations related. The given in the examples Weight percentages are active contents.

The microemulsions according to the invention are prepared by known methods of cosmetics production, according to the invention a primary surfactant, one or more cosurfactants, optionally one or more W / O emulsifiers, one or more liquid and / or solid oil phases, optionally a thickener and 0 to 4% by weight .-% salts are combined so that the primary / cosurfactant ratio can be set variably with a constant total amount of surfactant and yet microemulsions are obtained. Example 1 Makeup Remover Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.20 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.80 common salt 0.50 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 13,00 Sodium cocoamphoacetate 2.00 citric acid 00:50 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.82 common salt 1.62 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 11.00 Sodium cocoamphoacetate 4.22 citric acid 00:25 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.80 common salt 1.63 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 11.00 Cocamidopropyl betaine 4.22 citric acid 00:25 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.80 common salt 1.70 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Cocamidopropyl betaine 6.00 citric acid 00:20 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.80 common salt 1.70 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 13,00 Cocamidopropyl betaine 2.00 citric acid 00:50 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.82 common salt 1.62 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 13,00 Sodium cocoamphopropionate 2.00 citric acid 0.23 dicaprylyl 8.00 Glyceryl linoleate 3.00 glycerin 5.00 PEG-150 distearate 0.85 common salt 1.63 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 11.00 Sodium cocoamphopropionate 4.00 citric acid 0.25 dicaprylyl 8.00 Glyceryl linoleate 3.00 glycerin 5.00 PEG-150 distearate 0.85 common salt 1.63 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphopropionate 6.00 citric acid 0.40 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.83 common salt 0.81 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 13,00 Disodium cocoyl glutamate 2.00 citric acid 0.65 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.85 common salt 3.25 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 11.00 Disodium cocoyl glutamate 4.00 citric acid 1.40 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.90 common salt 3.25 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Disodium cocoyl glutamate 6.00 citric acid 3.25 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 1.00 common salt 3.25 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 13,00 Sodium lauroyl sarcosinate 2.00 citric acid 0.30 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.93 common salt 3.25 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 11.00 Sodium lauroyl sarcosinate 4.00 citric acid 0.38 dicaprylyl 8.00 Glyceryl linoleate 3.00 glycerin 5.00 PEG-150 distearate 1.10 common salt 3.25 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Sodium lauroyl sarcosinate 6.00 citric acid 0.60 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 1.10 common salt 3.25 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 13,00 Disodium cocoyl glutamate 2.00 citric acid 0.65 Coco Caprylat / Caprat 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 1.00 common salt 1.63 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 13,00 Disodium cocoyl glutamate 2.00 citric acid 0.67 Paraffinum liquidum 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 1.25 common salt 1.63 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.20 Paraffinum liquidum 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.80 common salt 0.50 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.20 Coco-caprylate / caprate 8.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.80 common salt 0.35 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.60 Paraffinum liquidum 4.00 dicaprylyl 4.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.75 common salt 0.50 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.20 Paraffinum liquidum 4.00 Coco-caprylate / caprate 4.00 Glyceryl linoleate 2.50 glycerin 5.00 PEG-150 distearate 0.75 common salt 0.50 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.30 dicaprylyl 2.00 Glyceryl linoleate 1.00 glycerin 5.00 PEG-150 distearate 0.30 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.20 Paraffinum liquidum 2.00 Glyceryl linoleate 1.00 glycerin 5.00 PEG-150 distearate 0.30 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.20 Paraffinum liquidum 2.00 Glyceryl isostearate 1.00 glycerin 5.00 PEG-150 distearate 0.30 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.20 Paraffinum liquidum 2.0 sorbitan 1.00 glycerin 5.00 PEG-150 distearate 0.30 Wt .-% Sodium laureth sulfate 11.00 Cocamidopropyl betaine 4.22 citric acid 00:25 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 common salt 1.70 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.20 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 common salt 0.50 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 11.00 Disodium cocoyl glutamate 4.00 citric acid 1.40 dicaprylyl 8.00 Glyceryl linoleate 2.50 glycerin 5.00 common salt 3.25 antioxidants qs preservative qs water ad 100,000 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.30 Cetearyl isononoate 2.00 Glyceryl isostearate 1.00 glycerin 5.00 PEG-150 distearate 0.30 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.20 Isopropyl palmitate 2.00 Glyceryl isostearate 1.00 glycerin 5.00 PEG-150 distearate 0.30 Wt .-% Sodium laureth sulfate 9.00 Sodium cocoamphoacetate 6.00 citric acid 1.20 Ethylhexyl cocoat 2.00 Glyceryl isostearate 1.00 glycerin 5.00 PEG-150 distearate 0.30

All of the listed examples illustrate the inexpensive properties of the oil-containing microemulsion gels or microemulsions according to the invention and these containing cleaning products.

Claims (25)

1. Process for the preparation of oil-containing microemulsions by the combination of a) a primary surfactant, b) one or more cosurfactants, c) optionally one or more W / O emulsifiers, d) one or more liquid and / or solid oil phases, e) optionally a thickener and f) the addition of 0 to 4% by weight of salts, characterized in that the primary / cosurfactant ratio can be set variably with a constant amount of total surfactant. 2. The method according to claim 1, characterized in that transparent Microemulsions can be obtained. 3. The method according to claim 1 or 2, characterized in that foaming Microemulsions can be obtained. 4. The method according to claim 1, 2 or 3, characterized in that the Total surfactant content, consisting of a) primary surfactant and b) cosurfactant, in the range is from 1 to 30% by weight. 5. The method according to claim 1, 2, 3 or 4, characterized in that the Total surfactant content is 25% by weight and the primary / cosurfactant ratio can be set variably in the range 14: 1 to 1:14. 6. The method according to any one of the preceding claims, characterized in that the proportion of W / O emulsifier in the range 0.1-25 wt .-% based on the Total preparation lies. 7. The method according to any one of the preceding claims, characterized in that the oil components in the range from 1 to 50% by weight, preferably between 1 to 40% by weight, based on the total preparation. 8. A process for the preparation of microemulsions according to one of the preceding claims by the combination of a) 15% by weight total surfactant content, b) 0.001-2.5% by weight of one or more W / O emulsifiers, c) 1-15% by weight of one or more oil phases, d) optionally a thickener and e) the addition of 0 to 4% by weight of salts, characterized in that the primary / cosurfactant ratio can be set variably and transparent microemulsions are obtained. 9. The method according to any one of the preceding claims, characterized in that that the primary and / or cosurfactant is selected from lauryl ether sulfate, Lauryl sulfate, betaines, amphoacetate, cocoamphopropionate, glutamate, Acylamino acids and their salts, acyl peptides, sarcosinates, taurates, Acyl lactylates, alaninates, arginates, valinates, prolinates, glycinates, aspartates, Propionates, carboxylic acids, ester carboxylic acids, ether carboxylic acids, sodium PEG-7 olive oil carboxylate, phosphoric acid esters and salts, acyl isethionate, Alkylaryl sulfonates, alkyl sulfonates, sulfosuccinates, alkyl ether sulfate, alkyl sulfates, Sodium alkyl sulfates, alkyl amines, alkyl imidazoles, ethoxylated amines, quaternary Surfactants, esterquats, alkylbetaine, alkylamidopropylbetaine, Alkyl amidopropyl hydroxysulfain, benzyl trialkylammonium chlorides or bromides, Alkyltrialkylammonium salts, alkyldimethylhydroxyethylammonium chlorides or bromides, Dialkyldimethylammonium chlorides or bromides, Dialkyl ethoxylate dimethyl ammonium chlorides or bromides, alkyl amide ethyl trimethyl ammonium ether sulfates, Alkyl pyridinium salts, cetyl trimethyl ammonium salts, acyl / dialkyl ethylenediamines, Disodium acyl amphodipropionate, disodium alkyl amphodiacetate, Sodium acylamphohydroxypropyl sulfonate, disodium acylamphodiacetate and sodium acylamphopropionate, and / or N-alkyl amino acids. 10. The method according to any one of the preceding claims, characterized in that the primary surfactant is selected from lauryl ether sulfate and / or lauryl sulfate, and the cosurfactant is selected from betaines, amphoacetate, cocoamphopropionate, Glutamate and / or sarcosinate. 11. The method according to any one of the preceding claims, characterized in that that the emulsifier is selected from glyceryl alcoholate, glyceryl monostearate, Glyceryl monoisostearate, glyceryl linoleate, glyceryl monooleate, Diglyceryl monostearate, diglyceryl monoisostearate, diglyceryl diisostearate, Propylene glycol monostearate, propylene glycol monoisostearate, propylene glycol diisostearate, Sorbitan monoisostearate, sucrose distearate, cetyl alcohol, stearyl alcohol, Arachidyl alcohol, behenyl alcohol, isobehenyl alcohol, 2-ethylhexylglycerol ether, Selachyl alcohol, chimyl alcohol, polyethylene glycol (2) stearyl ether (Steareth-2), Glyceryl monolaurate, glyceryl monocaprinate, glyceryl monocaprylate, Glyceryl sorbitan stearate, polyglyceryl-4 isostearate, polyglyceryl-2-sesquiisostearate, PEG-7 hydrogenated castor oil, PEG-40 sorbitan perisostearate, Isostearyl diglyceryl succinate, PEG-5 cholesteryl ether, triglycerol diisostearate, PEG-30 Dipolyhydroxystearate, decaglyceryl heptaoleate, polyglyceryl-3-diisostearate, PEG-8- Distearate and / or diglycerol dipolyhydroxystearate. 12. The method according to any one of the preceding claims, characterized in that the emulsifier is a lipophilic coemulsifier selected from glycerol esters, Propylene glycol esters, sorbitan esters, low ethoxylated glycerides, or diglycerides Triglycerides. 13. The method according to any one of the preceding claims, characterized in that the oil component d) is selected from the group of saturated esters and / or unsaturated, branched and / or unbranched alkane carboxylic acids or hydroxyalkanecarboxylic acids with a chain length of 1 to 44 carbon atoms and saturated and / or unsaturated, branched and / or unbranched alcohols a chain length of 1 to 44 carbon atoms, from the group of the esters aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols with a chain length of 1 to 30 carbon atoms, provided that the oil component or all of the oil components at Room temperature represent a liquid selected from the group of branched and unbranched hydrocarbons, silicone oils, lanolins, adipic acid esters, the butylene glycol diester, the dialkyl ether or carbonate, the group of saturated or unsaturated, branched alcohols, fatty acid triglycerides, olive oil, Sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, Palm kernel oil, silicone oil, dicapylyl carbonate, dicaprylyl ether, paraffin oil, coco Caprylate / caprate, caprylic / capric triglyceride, cyclomethicone, dimethicone, Octyldodecanol, butyloctyl salicylate and / or diethylhexylnaphthalate. 14. The method according to claim 2 to 13, characterized in that as an oil phase Ester oils are selected from the group cetearyl isononanoate, isopropyl myristate, Isopropyl palmitate, ethylhexyl cocoate, 2-ethylhexylaurate, 2-ethylhexypalmitate, Decyl oleate, octyl isostearate and / or isotridecyl isononaoate. 15. The method according to any one of the preceding claims, characterized in that as a thickener associative and / or non-associative thickener and / or cationic Polymers can be added. 16. The method according to any one of the preceding claims, characterized in that additional waxes can be added, selected from the group of the esters from saturated and / or unsaturated, branched and / or unbranched Alkane carboxylic acids or hydroxy carboxylic acids with a chain length of 1 to 80 C atoms and saturated and / or unsaturated, branched and / or unbranched Alcohols with a chain length of 1 to 80 carbon atoms, from the group of the esters aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols with a chain length of 1 to 80 carbon atoms provided the wax component or all of the wax components Represent a solid at room temperature, the natural waxes, the diester of Polyols and C10-C80 fatty acids, the ethoxylated waxes, the Triglyceride waxes, the C16-C60 fatty acids and / or C16-C80 fatty alcohols, the Mineral waxes. 17. The method according to any one of the preceding claims, characterized in that additionally antioxidants with a proportion of 0.001 to 30% by weight, especially preferably 0.001-20% by weight, in particular 0.001-10% by weight, based on the Total weight of the preparation can be added. 18. The method according to any one of the preceding claims, characterized in that usual cosmetic or dermatological substances, such as dyes, pigments, Powder substances, hydrophilic and / or lipophilic active substances, deodorants, Light stabilizers and / or other auxiliaries can be added. 19. Oil-containing microemulsions obtainable by a process according to one of the preceding claims. 20. Oily and foamable microemulsions obtainable by a process according to one of claims 2 to 18. 21. Oily and foamable microemulsions obtainable by a process according to one of claims 3 to 18. 22. Cosmetic cleaning agents based on oil-containing microemulsions after one of claims 19, 20 or 21. 23. Use of microemulsions according to one of claims 19, 20 or 21 as Shower gels, shampoos, cleansing preparations, hand washing products, Bath preparations, make-up removers or shaving products. 24. Use of microemulsions according to one of claims 19, 20 or 21 as Impregnation medium for wipes and / or tissue. 25. Use of microemulsions according to one of claims 19, 20 or 21 a donor, especially a pumpoamer.