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CU20200004A7 - Compuestos para tratar afecciones asociadas con la actividad nlrp - Google Patents

Compuestos para tratar afecciones asociadas con la actividad nlrp

Info

Publication number
CU20200004A7
CU20200004A7 CU2020000004A CU20200004A CU20200004A7 CU 20200004 A7 CU20200004 A7 CU 20200004A7 CU 2020000004 A CU2020000004 A CU 2020000004A CU 20200004 A CU20200004 A CU 20200004A CU 20200004 A7 CU20200004 A7 CU 20200004A7
Authority
CU
Cuba
Prior art keywords
compounds
conditions associated
treat conditions
nlrp
activity
Prior art date
Application number
CU2020000004A
Other languages
English (en)
Other versions
CU24615B1 (es
Inventor
Luigi Franchi
Shomir Ghosh
Gary Glick
Jason Katz
Jr Anthony William Opipari
William R Roush
Hans Martin Seidel
Dong-Ming Shen
Shankar Venkatraman
David Guenther Winkler
Original Assignee
Novartis Inflammasome Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Inflammasome Res Inc filed Critical Novartis Inflammasome Res Inc
Publication of CU20200004A7 publication Critical patent/CU20200004A7/es
Publication of CU24615B1 publication Critical patent/CU24615B1/es

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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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Abstract

En un aspecto, se proporcionan compuestos de la Fórmula AA,</p> <p>ESPACIO PARA FÓRMULA</p> <p><br /> en donde las variables indicadas en Ia Fórmula A pueden estar definidas en otras secciones de Ia presente.<br /> </p>
CU2020000004A 2017-07-24 2018-07-23 Compuestos para tratar afecciones asociadas con la actividad nlrp CU24615B1 (es)

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