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CR9868A - Derivados de indol 1,3-disustituido para su uso como moduladores de ppar - Google Patents

Derivados de indol 1,3-disustituido para su uso como moduladores de ppar

Info

Publication number
CR9868A
CR9868A CR9868A CR9868A CR9868A CR 9868 A CR9868 A CR 9868A CR 9868 A CR9868 A CR 9868A CR 9868 A CR9868 A CR 9868A CR 9868 A CR9868 A CR 9868A
Authority
CR
Costa Rica
Prior art keywords
disposed
ppar modulators
indol derivatives
indol
derivatives
Prior art date
Application number
CR9868A
Other languages
English (en)
Inventor
Lin Jack
Womack Patrick
Lee Byunghun
Shi Shenghua
Zhang Chao
Zuckerman Rebecca
R Artis Dean
N Ibrahim Prabha
Wang Weiru
Original Assignee
Plexxikon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plexxikon Inc filed Critical Plexxikon Inc
Publication of CR9868A publication Critical patent/CR9868A/es

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    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

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CA2621474A1 (en) 2007-03-15
IL189776A0 (en) 2008-08-07
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