CR9417A - 7-fluoro-1,3-dihidro-indol-2-ona oxazolidinonas como agentes antibacteriales - Google Patents
7-fluoro-1,3-dihidro-indol-2-ona oxazolidinonas como agentes antibacterialesInfo
- Publication number
- CR9417A CR9417A CR9417A CR9417A CR9417A CR 9417 A CR9417 A CR 9417A CR 9417 A CR9417 A CR 9417A CR 9417 A CR9417 A CR 9417A CR 9417 A CR9417 A CR 9417A
- Authority
- CR
- Costa Rica
- Prior art keywords
- antibacterial agents
- fluoro
- dihidro
- oxazolidinones
- ona
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title abstract 2
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La presente invencion proporciona un compuesto de formula I o una sal farmaceuticamente aceptable del mismo en la que R1 es alquilo C1-4, opcionalmente sustituido con un atomo de fluoro, o R 1 es un ciclopropilo o ciclopropilmetilo; y R2 es metilo o etilo. estos compuestos son Utiles como agentes antibacterianos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66871505P | 2005-04-06 | 2005-04-06 | |
| US68403305P | 2005-05-24 | 2005-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR9417A true CR9417A (es) | 2007-12-04 |
Family
ID=36636389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR9417A CR9417A (es) | 2005-04-06 | 2007-10-05 | 7-fluoro-1,3-dihidro-indol-2-ona oxazolidinonas como agentes antibacteriales |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7435751B2 (es) |
| EP (1) | EP1869030A1 (es) |
| JP (1) | JP2008534672A (es) |
| KR (1) | KR20070108938A (es) |
| AP (1) | AP2007004172A0 (es) |
| AR (1) | AR053839A1 (es) |
| AU (1) | AU2006231919A1 (es) |
| BR (1) | BRPI0610533A2 (es) |
| CA (1) | CA2603899A1 (es) |
| CR (1) | CR9417A (es) |
| DO (1) | DOP2006000080A (es) |
| GT (1) | GT200600133A (es) |
| IL (1) | IL186119A0 (es) |
| MX (1) | MX2007012386A (es) |
| NL (1) | NL1031525C2 (es) |
| NO (1) | NO20075505L (es) |
| PE (1) | PE20061301A1 (es) |
| TN (1) | TNSN07373A1 (es) |
| TW (1) | TW200716101A (es) |
| UY (1) | UY29452A1 (es) |
| WO (1) | WO2006106427A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005270951A1 (en) * | 2004-08-06 | 2006-02-16 | Pharmacia & Upjohn Company Llc | Oxazolidinones containing oxindoles as antibacterial agents |
| KR100891485B1 (ko) | 2007-10-29 | 2009-04-02 | 주식회사 만도 | 디스크 브레이크의 주차브레이크 장치 |
| US20090124737A1 (en) * | 2007-11-12 | 2009-05-14 | Eastman Chemical Company | Acrylic plastisol viscosity reducers |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0609905B1 (en) | 1988-09-15 | 2001-06-06 | PHARMACIA & UPJOHN COMPANY | 3-(Nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones |
| US5164510A (en) | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
| DE4425612A1 (de) | 1994-07-20 | 1996-04-04 | Bayer Ag | 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone |
| DE4425613A1 (de) | 1994-07-20 | 1996-01-25 | Bayer Ag | 5-gliedrige Heteroaryl-oxazolidinone |
| US6015429A (en) * | 1994-09-08 | 2000-01-18 | Gore Enterprise Holdings, Inc. | Procedures for introducing stents and stent-grafts |
| DE19649095A1 (de) | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue Heteroaryl-Oxazolidinone |
| DE19604223A1 (de) | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| CN1288462A (zh) | 1998-01-23 | 2001-03-21 | 法玛西雅厄普约翰美国公司 | 噁唑烷酮组合库、组合物和制备方法 |
| DE69912264T2 (de) | 1998-04-14 | 2004-07-22 | Samsung Fine Chemicals Co., Ltd. | Verfahren zur herstellung chiraler (s)-2,3-disubstituierter 1-propylamin-derivate |
| WO2000029396A1 (de) | 1998-11-17 | 2000-05-25 | Bayer Aktiengesellschaft | Neue substituierte phenyloxazolidon-derivate |
| JP2002531455A (ja) | 1998-11-27 | 2002-09-24 | ファルマシア・アンド・アップジョン・カンパニー | チオカルボニル官能基を有するオキサゾリジノン抗細菌剤 |
| BR0010982A (pt) | 1999-05-27 | 2002-03-05 | Upjohn Co | Novas oxazolidinonas bicìclicas como agentes antibacterianos |
| ATE321024T1 (de) | 2000-10-17 | 2006-04-15 | Pharmacia & Upjohn Co Llc | Verfahren zur herstellung von oxazolidinonverbindungen |
| WO2002081470A1 (en) | 2001-04-07 | 2002-10-17 | Astrazeneca Ab | Oxazolidinones containing a sulfonimid group as antibiotics |
| AU2002255803B2 (en) | 2001-04-20 | 2008-07-03 | Pharmacia And Upjohn Company | Process to prepare oxazolidinones |
| AR038536A1 (es) | 2002-02-25 | 2005-01-19 | Upjohn Co | N-aril-2-oxazolidinona-5- carboxamidas y sus derivados |
| US7012088B2 (en) * | 2003-02-24 | 2006-03-14 | Pharmacia & Upjohn Company | Indolone oxazolidinones and derivatives thereof |
| AU2005270951A1 (en) * | 2004-08-06 | 2006-02-16 | Pharmacia & Upjohn Company Llc | Oxazolidinones containing oxindoles as antibacterial agents |
-
2006
- 2006-03-26 AU AU2006231919A patent/AU2006231919A1/en not_active Abandoned
- 2006-03-27 KR KR1020077022657A patent/KR20070108938A/ko not_active Ceased
- 2006-03-27 CA CA002603899A patent/CA2603899A1/en not_active Abandoned
- 2006-03-27 JP JP2008504870A patent/JP2008534672A/ja not_active Withdrawn
- 2006-03-27 BR BRPI0610533-5A patent/BRPI0610533A2/pt not_active Application Discontinuation
- 2006-03-27 WO PCT/IB2006/000954 patent/WO2006106427A1/en not_active Ceased
- 2006-03-27 AP AP2007004172A patent/AP2007004172A0/xx unknown
- 2006-03-27 MX MX2007012386A patent/MX2007012386A/es unknown
- 2006-03-27 EP EP06727519A patent/EP1869030A1/en not_active Withdrawn
- 2006-03-30 US US11/393,961 patent/US7435751B2/en not_active Expired - Fee Related
- 2006-04-04 TW TW095112018A patent/TW200716101A/zh unknown
- 2006-04-04 AR ARP060101328A patent/AR053839A1/es unknown
- 2006-04-04 PE PE2006000363A patent/PE20061301A1/es not_active Application Discontinuation
- 2006-04-04 UY UY29452A patent/UY29452A1/es not_active Application Discontinuation
- 2006-04-05 DO DO2006000080A patent/DOP2006000080A/es unknown
- 2006-04-05 GT GT200600133A patent/GT200600133A/es unknown
- 2006-04-05 NL NL1031525A patent/NL1031525C2/nl not_active IP Right Cessation
-
2007
- 2007-09-20 IL IL186119A patent/IL186119A0/en unknown
- 2007-10-05 TN TNP2007000373A patent/TNSN07373A1/fr unknown
- 2007-10-05 CR CR9417A patent/CR9417A/es unknown
- 2007-10-31 NO NO20075505A patent/NO20075505L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MX2007012386A (es) | 2007-11-07 |
| NL1031525C2 (nl) | 2007-01-30 |
| EP1869030A1 (en) | 2007-12-26 |
| CA2603899A1 (en) | 2006-10-12 |
| IL186119A0 (en) | 2008-01-20 |
| AP2007004172A0 (en) | 2007-10-31 |
| TW200716101A (en) | 2007-05-01 |
| WO2006106427A8 (en) | 2007-12-06 |
| WO2006106427A1 (en) | 2006-10-12 |
| NO20075505L (no) | 2007-10-31 |
| US20060229349A1 (en) | 2006-10-12 |
| US7435751B2 (en) | 2008-10-14 |
| GT200600133A (es) | 2006-11-29 |
| UY29452A1 (es) | 2006-11-30 |
| JP2008534672A (ja) | 2008-08-28 |
| KR20070108938A (ko) | 2007-11-13 |
| NL1031525A1 (nl) | 2006-10-09 |
| AR053839A1 (es) | 2007-05-23 |
| PE20061301A1 (es) | 2007-02-09 |
| AU2006231919A1 (en) | 2006-10-12 |
| TNSN07373A1 (fr) | 2009-03-17 |
| BRPI0610533A2 (pt) | 2010-06-29 |
| DOP2006000080A (es) | 2006-12-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UY32730A (es) | Inhibidores de cyp17 | |
| MX343264B (es) | Ciertas amino-piridazinas, composiciones de las mismas y metodos de uso de los mismos. | |
| HRP20120323T1 (en) | Diarylhydantoin compounds | |
| AR083849A1 (es) | Antagonistas de mdm2 de espiro-oxindol | |
| CO6450621A2 (es) | Sulfonamidas nematocidas | |
| PE20150230A1 (es) | Nuevos diazaespirocicloalcanos y azaespirocicloalcanos | |
| CO6270320A2 (es) | Derivados de piperidina utiles como antagonistas del receptor orexina | |
| EA201100037A1 (ru) | Органические соединения | |
| ECSP12012293A (es) | Ciertas amino-pirimidinas, composicioines de las mismas y métodos para el uso de los mismos | |
| DK2074120T3 (da) | Tropan-forbindelser | |
| ECSP088966A (es) | Agonistas del receptor muscarínico que son efectivos en el tratamiento del dolor, la enfermedad de alzheimer y la esquizofrenia | |
| PA8561501A1 (es) | Lactamas como antagonistas de taquiquininas | |
| AR076362A1 (es) | Arilsulfonamidas 2,5-disustituidas antagonistas de ccr3, composiciones farmaceuticas que las contienen y uso de las mismas para el tratamiento y/o prevencion de patologias autoinmunes e inflamatorias, entre otras. | |
| UY29197A1 (es) | Compuestos de n-sulfonilaminobencil-2-fenoxiacetamida sustituidos | |
| UY31824A (es) | Nuevos compuestos | |
| BR0208812A (pt) | Derivados fenil heterociclil éter como inibidores de recaptação de serotonina | |
| CR9417A (es) | 7-fluoro-1,3-dihidro-indol-2-ona oxazolidinonas como agentes antibacteriales | |
| DE602006010738D1 (de) | Pyrroloä2,3-cüpyridinderivate | |
| CR9773A (es) | Derivados de glicilciclinas sustituidos con 9-aminocarbonilo | |
| UY29048A1 (es) | Oxazolidinonas que contienen oxindoles como agentes antibacterianos | |
| DOP2006000079A (es) | Una oxindoloxazolidinona como agente antibacteriano | |
| ECSP077225A (es) | Oxazolidinonas que contienen oxindoles como agentes antibacterianos | |
| DOP2005000150A (es) | Oxazolidinonas que contienen oxindoles como agentes antibacterianos | |
| EA201300160A1 (ru) | 2,3,5-тризамещенные тиофены и их применение | |
| UY31262A1 (es) | Compuestos de biciclolactama sustituida |