CO5200779A1 - COMPOSITIONS AND METHODS TO TREAT ALLERGIC AND INFLAMMATORY CONDITIONS WITH THESE RGIC AND INFLAMMATORY WITH THOSE - Google Patents
COMPOSITIONS AND METHODS TO TREAT ALLERGIC AND INFLAMMATORY CONDITIONS WITH THESE RGIC AND INFLAMMATORY WITH THOSEInfo
- Publication number
- CO5200779A1 CO5200779A1 CO00061954A CO00061954A CO5200779A1 CO 5200779 A1 CO5200779 A1 CO 5200779A1 CO 00061954 A CO00061954 A CO 00061954A CO 00061954 A CO00061954 A CO 00061954A CO 5200779 A1 CO5200779 A1 CO 5200779A1
- Authority
- CO
- Colombia
- Prior art keywords
- inflammatory
- methods
- inflammatory conditions
- rgic
- compositions
- Prior art date
Links
- 230000000172 allergic effect Effects 0.000 title abstract 3
- 208000010668 atopic eczema Diseases 0.000 title abstract 3
- 230000004968 inflammatory condition Effects 0.000 title abstract 3
- 230000002757 inflammatory effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 3
- 230000001387 anti-histamine Effects 0.000 abstract 3
- 239000000739 antihistaminic agent Substances 0.000 abstract 3
- 239000003172 expectorant agent Substances 0.000 abstract 3
- 230000003419 expectorant effect Effects 0.000 abstract 3
- 230000001624 sedative effect Effects 0.000 abstract 3
- 206010011224 Cough Diseases 0.000 abstract 2
- JBDGDEWWOUBZPM-XYPYZODXSA-N ambroxol Chemical group NC1=C(Br)C=C(Br)C=C1CN[C@@H]1CC[C@@H](O)CC1 JBDGDEWWOUBZPM-XYPYZODXSA-N 0.000 abstract 1
- 229960005174 ambroxol Drugs 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- JCCNYMKQOSZNPW-UHFFFAOYSA-N loratadine Chemical group C1CN(C(=O)OCC)CCC1=C1C2=NC=CC=C2CCC2=CC(Cl)=CC=C21 JCCNYMKQOSZNPW-UHFFFAOYSA-N 0.000 abstract 1
- 229960003088 loratadine Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Se describen métodos para tratar y/o prevenir condiciones alérgicas e inflamatorias con tos en humanos que requieran dicho tratamiento y/o prevención, los cuales comprenden administrar una cantidad efectiva de una antihistamina no sedante en combinación con un expectorante; las modalidades que se prefieren incluyen aquellas en las que la antihistamina no sedante es loratadina y el expectorante es ambroxol; se proveen también composiciones farmacéuticas novedosas para tratar y/o prevenir condiciones alérgicas e inflamatorias con tos en humanos, las cuales comprenden una cantidad efectiva de una antihistamina no sedante en combinación con un expectorante y un vehículo farmacéuticamente aceptable.Methods are described for treating and / or preventing allergic and inflammatory conditions with cough in humans that require such treatment and / or prevention, which comprise administering an effective amount of a non-sedating antihistamine in combination with an expectorant; Preferred embodiments include those in which the non-sedating antihistamine is loratadine and the expectorant is ambroxol; Novel pharmaceutical compositions are also provided to treat and / or prevent allergic and inflammatory conditions with cough in humans, which comprise an effective amount of a non-sedating antihistamine in combination with an expectorant and a pharmaceutically acceptable carrier.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19331000P | 2000-03-30 | 2000-03-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5200779A1 true CO5200779A1 (en) | 2002-09-27 |
Family
ID=22713096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO00061954A CO5200779A1 (en) | 2000-03-30 | 2000-08-17 | COMPOSITIONS AND METHODS TO TREAT ALLERGIC AND INFLAMMATORY CONDITIONS WITH THESE RGIC AND INFLAMMATORY WITH THOSE |
Country Status (13)
| Country | Link |
|---|---|
| CN (1) | CN1422162A (en) |
| AR (1) | AR025308A1 (en) |
| AU (2) | AU4786701A (en) |
| BR (1) | BR0003648A (en) |
| CO (1) | CO5200779A1 (en) |
| CR (1) | CR6232A (en) |
| NZ (1) | NZ520826A (en) |
| PA (1) | PA8500101A1 (en) |
| PE (1) | PE20010576A1 (en) |
| SG (1) | SG96611A1 (en) |
| TW (1) | TWI243671B (en) |
| WO (1) | WO2001074341A2 (en) |
| ZA (1) | ZA200102605B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1323662C (en) * | 2004-06-18 | 2007-07-04 | 江苏恒瑞医药股份有限公司 | Pharmaceutical composition containing ambroxol and erdosteine or acetylcysteine and application thereof |
| WO2005123052A1 (en) * | 2004-06-18 | 2005-12-29 | Jiangsu Hengrui Medicine Co., Ltd. | Drug composition containing ambroxol and erdosteine or acetylcysteine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4552899A (en) * | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
| US4783465A (en) * | 1984-04-09 | 1988-11-08 | Analgesic Associates | Cough/cold mixtures comprising non-sedating antihistamine drugs |
| US4829064A (en) * | 1987-06-08 | 1989-05-09 | Analgesic Associates | Cough/cold mixtures comprising non-sedating antihistamine drugs |
| AU7604094A (en) * | 1993-09-07 | 1995-03-27 | Procter & Gamble Company, The | Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive |
| US6160020A (en) * | 1996-12-20 | 2000-12-12 | Mcneill-Ppc, Inc. | Alkali metal and alkaline-earth metal salts of acetaminophen |
-
2000
- 2000-08-17 CR CR6232A patent/CR6232A/en not_active Application Discontinuation
- 2000-08-17 CO CO00061954A patent/CO5200779A1/en not_active Application Discontinuation
- 2000-08-17 AR ARP000104255A patent/AR025308A1/en not_active Application Discontinuation
- 2000-08-17 PA PA20008500101A patent/PA8500101A1/en unknown
- 2000-08-17 BR BR0003648-0A patent/BR0003648A/en not_active Application Discontinuation
- 2000-08-17 PE PE2000000839A patent/PE20010576A1/en not_active Application Discontinuation
-
2001
- 2001-03-28 AU AU4786701A patent/AU4786701A/en active Pending
- 2001-03-28 WO PCT/US2001/010019 patent/WO2001074341A2/en not_active Ceased
- 2001-03-28 TW TW090107406A patent/TWI243671B/en not_active IP Right Cessation
- 2001-03-28 NZ NZ520826A patent/NZ520826A/en unknown
- 2001-03-28 SG SG200101948A patent/SG96611A1/en unknown
- 2001-03-28 CN CN01807679A patent/CN1422162A/en active Pending
- 2001-03-28 AU AU2001247867A patent/AU2001247867B2/en not_active Ceased
- 2001-03-29 ZA ZA200102605A patent/ZA200102605B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200102605B (en) | 2001-10-03 |
| PA8500101A1 (en) | 2002-09-17 |
| WO2001074341A3 (en) | 2002-05-16 |
| TWI243671B (en) | 2005-11-21 |
| AU4786701A (en) | 2001-10-15 |
| CN1422162A (en) | 2003-06-04 |
| AR025308A1 (en) | 2002-11-20 |
| PE20010576A1 (en) | 2001-05-08 |
| AU2001247867B2 (en) | 2005-09-01 |
| CR6232A (en) | 2008-12-01 |
| NZ520826A (en) | 2004-07-30 |
| WO2001074341A2 (en) | 2001-10-11 |
| BR0003648A (en) | 2002-01-02 |
| SG96611A1 (en) | 2003-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |