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CO5200779A1 - COMPOSITIONS AND METHODS TO TREAT ALLERGIC AND INFLAMMATORY CONDITIONS WITH THESE RGIC AND INFLAMMATORY WITH THOSE - Google Patents

COMPOSITIONS AND METHODS TO TREAT ALLERGIC AND INFLAMMATORY CONDITIONS WITH THESE RGIC AND INFLAMMATORY WITH THOSE

Info

Publication number
CO5200779A1
CO5200779A1 CO00061954A CO00061954A CO5200779A1 CO 5200779 A1 CO5200779 A1 CO 5200779A1 CO 00061954 A CO00061954 A CO 00061954A CO 00061954 A CO00061954 A CO 00061954A CO 5200779 A1 CO5200779 A1 CO 5200779A1
Authority
CO
Colombia
Prior art keywords
inflammatory
methods
inflammatory conditions
rgic
compositions
Prior art date
Application number
CO00061954A
Other languages
Spanish (es)
Inventor
Lugo Sergio Rolando Ulloa
Ramos Jose De Jesus Villacampa
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of CO5200779A1 publication Critical patent/CO5200779A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describen métodos para tratar y/o prevenir condiciones alérgicas e inflamatorias con tos en humanos que requieran dicho tratamiento y/o prevención, los cuales comprenden administrar una cantidad efectiva de una antihistamina no sedante en combinación con un expectorante; las modalidades que se prefieren incluyen aquellas en las que la antihistamina no sedante es loratadina y el expectorante es ambroxol; se proveen también composiciones farmacéuticas novedosas para tratar y/o prevenir condiciones alérgicas e inflamatorias con tos en humanos, las cuales comprenden una cantidad efectiva de una antihistamina no sedante en combinación con un expectorante y un vehículo farmacéuticamente aceptable.Methods are described for treating and / or preventing allergic and inflammatory conditions with cough in humans that require such treatment and / or prevention, which comprise administering an effective amount of a non-sedating antihistamine in combination with an expectorant; Preferred embodiments include those in which the non-sedating antihistamine is loratadine and the expectorant is ambroxol; Novel pharmaceutical compositions are also provided to treat and / or prevent allergic and inflammatory conditions with cough in humans, which comprise an effective amount of a non-sedating antihistamine in combination with an expectorant and a pharmaceutically acceptable carrier.

CO00061954A 2000-03-30 2000-08-17 COMPOSITIONS AND METHODS TO TREAT ALLERGIC AND INFLAMMATORY CONDITIONS WITH THESE RGIC AND INFLAMMATORY WITH THOSE CO5200779A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19331000P 2000-03-30 2000-03-30

Publications (1)

Publication Number Publication Date
CO5200779A1 true CO5200779A1 (en) 2002-09-27

Family

ID=22713096

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00061954A CO5200779A1 (en) 2000-03-30 2000-08-17 COMPOSITIONS AND METHODS TO TREAT ALLERGIC AND INFLAMMATORY CONDITIONS WITH THESE RGIC AND INFLAMMATORY WITH THOSE

Country Status (13)

Country Link
CN (1) CN1422162A (en)
AR (1) AR025308A1 (en)
AU (2) AU4786701A (en)
BR (1) BR0003648A (en)
CO (1) CO5200779A1 (en)
CR (1) CR6232A (en)
NZ (1) NZ520826A (en)
PA (1) PA8500101A1 (en)
PE (1) PE20010576A1 (en)
SG (1) SG96611A1 (en)
TW (1) TWI243671B (en)
WO (1) WO2001074341A2 (en)
ZA (1) ZA200102605B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1323662C (en) * 2004-06-18 2007-07-04 江苏恒瑞医药股份有限公司 Pharmaceutical composition containing ambroxol and erdosteine or acetylcysteine and application thereof
WO2005123052A1 (en) * 2004-06-18 2005-12-29 Jiangsu Hengrui Medicine Co., Ltd. Drug composition containing ambroxol and erdosteine or acetylcysteine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552899A (en) * 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4783465A (en) * 1984-04-09 1988-11-08 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
US4829064A (en) * 1987-06-08 1989-05-09 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
AU7604094A (en) * 1993-09-07 1995-03-27 Procter & Gamble Company, The Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive
US6160020A (en) * 1996-12-20 2000-12-12 Mcneill-Ppc, Inc. Alkali metal and alkaline-earth metal salts of acetaminophen

Also Published As

Publication number Publication date
ZA200102605B (en) 2001-10-03
PA8500101A1 (en) 2002-09-17
WO2001074341A3 (en) 2002-05-16
TWI243671B (en) 2005-11-21
AU4786701A (en) 2001-10-15
CN1422162A (en) 2003-06-04
AR025308A1 (en) 2002-11-20
PE20010576A1 (en) 2001-05-08
AU2001247867B2 (en) 2005-09-01
CR6232A (en) 2008-12-01
NZ520826A (en) 2004-07-30
WO2001074341A2 (en) 2001-10-11
BR0003648A (en) 2002-01-02
SG96611A1 (en) 2003-06-16

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