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CO2017000558A2 - Variantes de proteínas de unión al factor h - Google Patents

Variantes de proteínas de unión al factor h

Info

Publication number
CO2017000558A2
CO2017000558A2 CONC2017/0000558A CO2017000558A CO2017000558A2 CO 2017000558 A2 CO2017000558 A2 CO 2017000558A2 CO 2017000558 A CO2017000558 A CO 2017000558A CO 2017000558 A2 CO2017000558 A2 CO 2017000558A2
Authority
CO
Colombia
Prior art keywords
binding proteins
variants
factor binding
proteins
strain
Prior art date
Application number
CONC2017/0000558A
Other languages
English (en)
Inventor
Peter T Beernink
Original Assignee
Childrens Hospital & Res Center At Oakland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Hospital & Res Center At Oakland filed Critical Childrens Hospital & Res Center At Oakland
Publication of CO2017000558A2 publication Critical patent/CO2017000558A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se brindan proteínas variantes de unión al factor H que pueden provocar anticuerpos bactericidas para al menos una cepa de Neisseria meningitidis, composiciones que comprenden dichas proteínas y métodos de uso de dichas proteínas.
CONC2017/0000558A 2014-07-23 2017-01-23 Variantes de proteínas de unión al factor h CO2017000558A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462028123P 2014-07-23 2014-07-23
PCT/US2015/041616 WO2016014719A1 (en) 2014-07-23 2015-07-22 Factor h binding protein variants and methods of use thereof

Publications (1)

Publication Number Publication Date
CO2017000558A2 true CO2017000558A2 (es) 2017-06-20

Family

ID=55163727

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2017/0000558A CO2017000558A2 (es) 2014-07-23 2017-01-23 Variantes de proteínas de unión al factor h

Country Status (15)

Country Link
US (10) US10266572B2 (es)
EP (2) EP3172224B1 (es)
JP (4) JP6796057B2 (es)
KR (2) KR102761870B1 (es)
CN (3) CN112851768A (es)
AU (5) AU2015292615B2 (es)
BR (1) BR112017001417B1 (es)
CA (2) CA2955802C (es)
CO (1) CO2017000558A2 (es)
CR (1) CR20170020A (es)
ES (1) ES2922554T3 (es)
MX (3) MX382409B (es)
NZ (2) NZ729206A (es)
RU (1) RU2714248C2 (es)
WO (1) WO2016014719A1 (es)

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Also Published As

Publication number Publication date
US20210101942A1 (en) 2021-04-08
RU2017104742A3 (es) 2019-02-27
AU2025202774A1 (en) 2025-05-08
US20200109179A1 (en) 2020-04-09
AU2019264600A1 (en) 2019-12-05
BR112017001417A2 (pt) 2017-11-21
US10487122B2 (en) 2019-11-26
CA2955802A1 (en) 2016-01-28
US20240025951A1 (en) 2024-01-25
US20190225655A1 (en) 2019-07-25
US10836799B2 (en) 2020-11-17
KR102752259B1 (ko) 2025-01-13
BR112017001417B1 (pt) 2023-11-07
KR20170028442A (ko) 2017-03-13
CA2955802C (en) 2023-10-31
CN119613509A (zh) 2025-03-14
WO2016014719A1 (en) 2016-01-28
JP6796057B2 (ja) 2020-12-02
AU2021203828A1 (en) 2021-07-08
AU2023204391B2 (en) 2025-01-23
NZ766444A (en) 2024-01-26
JP2021000121A (ja) 2021-01-07
EP4074726A3 (en) 2022-11-23
MX382409B (es) 2025-03-13
AU2019264600B2 (en) 2021-04-01
US20200095288A1 (en) 2020-03-26
NZ729206A (en) 2022-07-01
MX2023000204A (es) 2023-02-09
US20250136648A1 (en) 2025-05-01
US11834476B2 (en) 2023-12-05
NZ766003A (en) 2024-01-26
RU2714248C2 (ru) 2020-02-13
CN106715464B (zh) 2021-03-16
US12269849B2 (en) 2025-04-08
US10995122B2 (en) 2021-05-04
EP4074726A2 (en) 2022-10-19
EP3172224B1 (en) 2022-06-29
JP2025108722A (ja) 2025-07-23
MX2017001038A (es) 2018-02-09
EP3172224A4 (en) 2018-04-18
KR20230155595A (ko) 2023-11-10
US20240101610A1 (en) 2024-03-28
CR20170020A (es) 2017-08-10
US10266572B2 (en) 2019-04-23
US20170183384A1 (en) 2017-06-29
US11673920B2 (en) 2023-06-13
JP7719046B2 (ja) 2025-08-05
US12129282B2 (en) 2024-10-29
MX2021005373A (es) 2021-07-06
CN106715464A (zh) 2017-05-24
RU2017104742A (ru) 2018-08-29
AU2015292615A1 (en) 2017-03-16
NZ766005A (en) 2024-03-22
JP7221917B2 (ja) 2023-02-14
ES2922554T3 (es) 2022-09-16
US20210340191A1 (en) 2021-11-04
KR102761870B1 (ko) 2025-02-05
JP2017522877A (ja) 2017-08-17
AU2021203828B2 (en) 2023-04-13
AU2023204391A1 (en) 2023-08-03
US20250154206A1 (en) 2025-05-15
CN112851768A (zh) 2021-05-28
JP2023011916A (ja) 2023-01-24
RU2020105192A (ru) 2020-02-12
EP3172224A1 (en) 2017-05-31
AU2015292615B2 (en) 2019-10-24
CA3212723A1 (en) 2016-01-28

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