MX2023000204A - Variantes de proteinas de union al factor h y metodos de uso de estas. - Google Patents
Variantes de proteinas de union al factor h y metodos de uso de estas.Info
- Publication number
- MX2023000204A MX2023000204A MX2023000204A MX2023000204A MX2023000204A MX 2023000204 A MX2023000204 A MX 2023000204A MX 2023000204 A MX2023000204 A MX 2023000204A MX 2023000204 A MX2023000204 A MX 2023000204A MX 2023000204 A MX2023000204 A MX 2023000204A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- factor
- binding protein
- protein variants
- proteins
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se brindan proteínas variantes de unión al factor H que pueden provocar anticuerpos bactericidas para al menos una cepa de Neisseria meningitidis, composiciones que comprenden dichas proteínas y métodos de uso de dichas proteínas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462028123P | 2014-07-23 | 2014-07-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023000204A true MX2023000204A (es) | 2023-02-09 |
Family
ID=55163727
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017001038A MX382409B (es) | 2014-07-23 | 2015-07-22 | Variantes de proteinas de unión al factor h y métodos de uso de estas. |
| MX2023000204A MX2023000204A (es) | 2014-07-23 | 2017-01-23 | Variantes de proteinas de union al factor h y metodos de uso de estas. |
| MX2021005373A MX2021005373A (es) | 2014-07-23 | 2017-01-23 | Variantes de proteinas de union al factor h y metodos de uso de estas. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017001038A MX382409B (es) | 2014-07-23 | 2015-07-22 | Variantes de proteinas de unión al factor h y métodos de uso de estas. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021005373A MX2021005373A (es) | 2014-07-23 | 2017-01-23 | Variantes de proteinas de union al factor h y metodos de uso de estas. |
Country Status (15)
| Country | Link |
|---|---|
| US (10) | US10266572B2 (es) |
| EP (2) | EP4074726A3 (es) |
| JP (4) | JP6796057B2 (es) |
| KR (2) | KR102752259B1 (es) |
| CN (3) | CN106715464B (es) |
| AU (5) | AU2015292615B2 (es) |
| BR (1) | BR112017001417B1 (es) |
| CA (2) | CA3212723A1 (es) |
| CO (1) | CO2017000558A2 (es) |
| CR (1) | CR20170020A (es) |
| ES (1) | ES2922554T3 (es) |
| MX (3) | MX382409B (es) |
| NZ (2) | NZ729206A (es) |
| RU (1) | RU2714248C2 (es) |
| WO (1) | WO2016014719A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2661569T3 (es) | 2010-03-30 | 2018-04-02 | Children's Hospital & Research Center At Oakland | Proteínas de unión al factor H (fHbp) con propiedades alteradas y métodos de uso de las mismas |
| CN106715464B (zh) | 2014-07-23 | 2021-03-16 | 奥克兰儿童医院及研究中心 | 因子h结合蛋白变体及其使用方法 |
| GB201614687D0 (en) * | 2016-08-31 | 2016-10-12 | Univ Oxford Innovation Ltd | fHbp scaffold |
| WO2018093176A2 (ko) | 2016-11-16 | 2018-05-24 | 주식회사 케이엠더블유 | 적층구조의 mimo 안테나 어셈블리 |
| KR101855133B1 (ko) | 2016-11-16 | 2018-05-08 | 주식회사 케이엠더블유 | 적층구조의 mimo 안테나 어셈블리 |
| WO2019110569A1 (en) * | 2017-12-04 | 2019-06-13 | De Staat Der Nederlanden, Vert. Door De Minister Van Vws, Ministerie Van Volksgezondheid, Welzijn En Sport | An improved process for producing outer membrane vesicles |
| EP3607967A1 (en) | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| GB202016604D0 (en) | 2020-10-20 | 2020-12-02 | Univ Of Oxford | Compositions and methods for inducing an immune response |
| WO2022178196A1 (en) * | 2021-02-19 | 2022-08-25 | Sanofi Pasteur Inc. | Meningococcal b recombinant vaccine |
| TW202423477A (zh) | 2022-08-03 | 2024-06-16 | 美商賽諾菲巴斯德公司 | 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物 |
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| HU212924B (en) | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| NZ253137A (en) | 1992-06-25 | 1996-08-27 | Smithkline Beecham Biolog | Vaccine comprising antigen and/or antigenic composition, qs21 (quillaja saponaria molina extract) and 3 de-o-acylated monophosphoryl lipid a. |
| US5776468A (en) | 1993-03-23 | 1998-07-07 | Smithkline Beecham Biologicals (S.A.) | Vaccine compositions containing 3-0 deacylated monophosphoryl lipid A |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| IL117483A (en) | 1995-03-17 | 2008-03-20 | Bernard Brodeur | MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K. |
| GB9513261D0 (en) | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
| DE69838294T2 (de) | 1997-05-20 | 2009-08-13 | Ottawa Health Research Institute, Ottawa | Verfahren zur Herstellung von Nukleinsäurekonstrukten |
| GB9712347D0 (en) | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
| EP1009382B1 (en) | 1997-09-05 | 2003-06-18 | GlaxoSmithKline Biologicals S.A. | Oil in water emulsions containing saponins |
| US6303114B1 (en) | 1998-03-05 | 2001-10-16 | The Medical College Of Ohio | IL-12 enhancement of immune responses to T-independent antigens |
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| US20070026021A1 (en) | 1998-05-01 | 2007-02-01 | Chiron S.R.I. | Neisseria meningitidis antigens and compositions |
| PT1944371E (pt) | 1998-05-01 | 2015-07-13 | Novartis Ag | Antigénios e composições da neisseria meningitidis |
| GB9817052D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
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| CN1227030C (zh) | 1999-04-19 | 2005-11-16 | 史密丝克莱恩比彻姆生物有限公司 | 包含皂甙和免疫刺激寡核苷酸的佐剂组合物 |
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| AU765824B2 (en) | 1999-09-24 | 2003-10-02 | Smithkline Beecham Biologicals (Sa) | Vaccines |
| WO2001034642A2 (en) | 1999-11-12 | 2001-05-17 | University Of Iowa Research Foundation | Control of neisserial membrane synthesis |
| AU2013206190A1 (en) | 1999-11-29 | 2013-06-27 | Novartis Vaccines And Diagnostics S.R.L. | Compositions comprising Neisseria meningitidis antigens from serogroups B and C as well as a further antigen |
| JP2003520248A (ja) | 2000-01-17 | 2003-07-02 | カイロン エセ.ピー.アー. | N.meningitidis血清型b外膜タンパク質を含む外膜小胞(omv)ワクチン |
| EP1790660B1 (en) | 2000-02-28 | 2012-06-20 | Novartis Vaccines and Diagnostics S.r.l. | Heterologous expression of neisserial proteins |
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| WO2013078223A1 (en) | 2011-11-23 | 2013-05-30 | Children's Hospital & Research Center Oakland | Anti-factor h binding protein antibodies and methods of use thereof |
| KR101763625B1 (ko) * | 2012-03-09 | 2017-08-01 | 화이자 인코포레이티드 | 수막염균 조성물 및 이의 사용 방법 |
| GB201215005D0 (en) | 2012-08-23 | 2012-10-10 | Isis Innovation | Stabilised meningitis vaccine |
| KR20160034401A (ko) | 2013-08-02 | 2016-03-29 | 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 | 비-천연적으로 발생하는 인자 h 결합 단백질(fhbp) 및 이의 사용 방법 |
| MX373277B (es) | 2014-02-28 | 2020-05-20 | Glaxosmithkline Biologicals Sa | Polipeptidos fhbp meningococicos modificados. |
| KR20150128099A (ko) | 2014-05-08 | 2015-11-18 | (주)엘지하우시스 | Pla 및 pha 혼합수지를 이용한 벽지 및 그 제조 방법 |
| CN107349423B (zh) * | 2014-06-24 | 2021-03-19 | 上海生物制品研究所有限责任公司 | 一种脑膜炎球菌抗原组合及其应用 |
| AR102324A1 (es) * | 2014-07-17 | 2017-02-22 | Glaxosmithkline Biologicals Sa | Polipéptidos fhbp (proteína de unión al factor h) meningocócicos modificados |
| CN106715464B (zh) | 2014-07-23 | 2021-03-16 | 奥克兰儿童医院及研究中心 | 因子h结合蛋白变体及其使用方法 |
| EP3607967A1 (en) * | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
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2015
- 2015-07-22 CN CN201580043542.XA patent/CN106715464B/zh active Active
- 2015-07-22 KR KR1020177004378A patent/KR102752259B1/ko active Active
- 2015-07-22 WO PCT/US2015/041616 patent/WO2016014719A1/en not_active Ceased
- 2015-07-22 CN CN202110192031.1A patent/CN112851768A/zh active Pending
- 2015-07-22 EP EP22174947.6A patent/EP4074726A3/en active Pending
- 2015-07-22 JP JP2017503089A patent/JP6796057B2/ja active Active
- 2015-07-22 RU RU2017104742A patent/RU2714248C2/ru active
- 2015-07-22 BR BR112017001417-3A patent/BR112017001417B1/pt active IP Right Grant
- 2015-07-22 KR KR1020237036853A patent/KR102761870B1/ko active Active
- 2015-07-22 NZ NZ729206A patent/NZ729206A/en unknown
- 2015-07-22 ES ES15824545T patent/ES2922554T3/es active Active
- 2015-07-22 CA CA3212723A patent/CA3212723A1/en active Pending
- 2015-07-22 US US15/327,346 patent/US10266572B2/en active Active
- 2015-07-22 NZ NZ766005A patent/NZ766005A/en unknown
- 2015-07-22 CN CN202411821930.3A patent/CN119613509A/zh active Pending
- 2015-07-22 CR CR20170020A patent/CR20170020A/es unknown
- 2015-07-22 MX MX2017001038A patent/MX382409B/es unknown
- 2015-07-22 AU AU2015292615A patent/AU2015292615B2/en active Active
- 2015-07-22 CA CA2955802A patent/CA2955802C/en active Active
- 2015-07-22 EP EP15824545.6A patent/EP3172224B1/en active Active
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2017
- 2017-01-23 CO CONC2017/0000558A patent/CO2017000558A2/es unknown
- 2017-01-23 MX MX2023000204A patent/MX2023000204A/es unknown
- 2017-01-23 MX MX2021005373A patent/MX2021005373A/es unknown
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2019
- 2019-02-28 US US16/288,760 patent/US10487122B2/en active Active
- 2019-10-11 US US16/600,282 patent/US10995122B2/en active Active
- 2019-10-11 US US16/600,259 patent/US10836799B2/en active Active
- 2019-11-14 AU AU2019264600A patent/AU2019264600B2/en active Active
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2020
- 2020-09-23 JP JP2020158515A patent/JP7221917B2/ja active Active
- 2020-10-07 US US17/065,386 patent/US11834476B2/en active Active
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2021
- 2021-04-02 US US17/221,646 patent/US11673920B2/en active Active
- 2021-06-10 AU AU2021203828A patent/AU2021203828B2/en active Active
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2022
- 2022-11-10 JP JP2022180069A patent/JP7719046B2/ja active Active
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2023
- 2023-05-12 US US18/316,594 patent/US12129282B2/en active Active
- 2023-07-07 AU AU2023204391A patent/AU2023204391B2/en active Active
- 2023-10-24 US US18/493,141 patent/US12269849B2/en active Active
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2024
- 2024-09-19 US US18/890,476 patent/US20250136648A1/en active Pending
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2025
- 2025-01-14 US US19/020,854 patent/US20250154206A1/en active Pending
- 2025-04-22 AU AU2025202774A patent/AU2025202774A1/en active Pending
- 2025-04-24 JP JP2025071948A patent/JP2025108722A/ja active Pending
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