CN1927293A - Chinese medicine composition for treating skin burn and scald - Google Patents
Chinese medicine composition for treating skin burn and scald Download PDFInfo
- Publication number
- CN1927293A CN1927293A CN 200610112873 CN200610112873A CN1927293A CN 1927293 A CN1927293 A CN 1927293A CN 200610112873 CN200610112873 CN 200610112873 CN 200610112873 A CN200610112873 A CN 200610112873A CN 1927293 A CN1927293 A CN 1927293A
- Authority
- CN
- China
- Prior art keywords
- radix
- chinese medicine
- preparation
- rhizoma rhei
- medicine preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 20
- 206010053615 Thermal burn Diseases 0.000 title claims abstract description 6
- 231100000075 skin burn Toxicity 0.000 title claims description 3
- 239000000203 mixture Substances 0.000 title abstract description 8
- 238000000034 method Methods 0.000 claims abstract description 6
- 239000002552 dosage form Substances 0.000 claims abstract description 4
- 238000002360 preparation method Methods 0.000 claims description 30
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 20
- 239000002674 ointment Substances 0.000 claims description 10
- 241000581682 Sanguisorba Species 0.000 claims description 9
- 235000008282 Sanguisorba officinalis Nutrition 0.000 claims description 9
- 239000002994 raw material Substances 0.000 claims description 7
- -1 antiseptic Substances 0.000 claims description 6
- 239000000284 extract Substances 0.000 claims description 6
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 4
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 claims description 4
- 201000010099 disease Diseases 0.000 claims description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 4
- 230000002500 effect on skin Effects 0.000 claims description 4
- 230000003612 virological effect Effects 0.000 claims description 4
- 229940126678 chinese medicines Drugs 0.000 claims description 2
- 239000002671 adjuvant Substances 0.000 claims 2
- 230000002421 anti-septic effect Effects 0.000 claims 2
- 239000003963 antioxidant agent Substances 0.000 claims 2
- 230000003078 antioxidant effect Effects 0.000 claims 2
- 239000003623 enhancer Substances 0.000 claims 2
- 239000000344 soap Substances 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 239000000080 wetting agent Substances 0.000 claims 2
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 claims 1
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims 1
- 235000021355 Stearic acid Nutrition 0.000 claims 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims 1
- 239000007766 cera flava Substances 0.000 claims 1
- 229940057995 liquid paraffin Drugs 0.000 claims 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims 1
- 229940056211 paraffin Drugs 0.000 claims 1
- 239000012188 paraffin wax Substances 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 229950008882 polysorbate Drugs 0.000 claims 1
- 229920000136 polysorbate Polymers 0.000 claims 1
- 229920002545 silicone oil Polymers 0.000 claims 1
- 239000008117 stearic acid Substances 0.000 claims 1
- 229940099259 vaseline Drugs 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 241000700605 Viruses Species 0.000 abstract 1
- 208000002352 blister Diseases 0.000 abstract 1
- 239000007788 liquid Substances 0.000 description 4
- 239000012567 medical material Substances 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 238000010992 reflux Methods 0.000 description 4
- 230000000202 analgesic effect Effects 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000001035 drying Methods 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
The invention relates to a Chinese medicinal composition for the treatment of skin scald, burns and skin virus bleb, as well as the preparing process. The medicament can be prepared into any of the clinically usable dosage forms.
Description
Technical field:
The present invention relates to a kind of Chinese medicine composition and preparation technology thereof, particularly a kind of skin scald, burn of being used for, the prescription and the preparation technology thereof of diseases such as dermal viral herpes.
Background technology:
Skin scald, burn, diseases such as dermal viral herpes are clinically to see that symptom, the traditional Chinese medical science often take heat clearing away, removing heat from blood, detoxifcation, analgesic means that it is treated more, and evident in efficacy.But shortcomings such as in the practice, onset is slow because many Chinese medicines have, the course of treatment is long have a strong impact on its clinical practice.
Chinese medicine composition of the present invention can collect the elite and thick the putting of medicine, is easy to dissolving and absorption, and curative effect is fast, and administration time is short, and therefore, curative effect is better.
The purpose of this invention is to provide a kind of skin scald, burn of being used for, the pure Chinese medicine composition and the multiple appropriate formulation thereof of diseases such as dermal viral herpes, said preparation is rapid-action, evident in efficacy, is worthy of popularization.
Summary of the invention:
The present invention relates to a kind of prescription and preparation technology thereof of Chinese medicine preparation, it is characterized in that, the preparation of per 1000 dosage units in basic side is prepared from by following proportion raw material:
50～200 parts of 50～200 portions of Radix Sanguisorbaes of Radix Et Rhizoma Rhei.
Preferably:
100 parts of 100 portions of Radix Sanguisorbaes of Radix Et Rhizoma Rhei.
The preparation of per 1000 dosage units of the present invention side of deriving a is prepared from by following proportion raw material:
15～60 parts of 50～200 portions of Rhizoma Coptidis of 50～200 portions of Radix Sanguisorbaes of Radix Et Rhizoma Rhei.
Preferably:
30 parts of 100 portions of Rhizoma Coptidis of 100 portions of Radix Sanguisorbaes of Radix Et Rhizoma Rhei.
The preparation of per 1000 dosage units of the present invention side of deriving b is prepared from by following proportion raw material:
2.5～10 parts of 50～200 parts of Borneolum Syntheticums of 50～200 portions of Radix Sanguisorbaes of Radix Et Rhizoma Rhei.
Preferably:
5 parts of 100 parts of Borneolum Syntheticums of 100 portions of Radix Sanguisorbaes of Radix Et Rhizoma Rhei.
The preparation of per 1000 dosage units of the present invention side of deriving c is prepared from by following proportion raw material:
50～200 part of 75%～95% ethanol of 50～200 portions of Radix Sanguisorbaes of Radix Et Rhizoma Rhei is an amount of.
Preferably:
100 part of 75%～95% ethanol of 100 portions of Radix Sanguisorbaes of Radix Et Rhizoma Rhei is an amount of.
Radix Et Rhizoma Rhei clearing away heat-fire, astringing to arrest bleeding in the raw material that externally-applied ointment of the present invention adopts; The Radix Sanguisorbae cooling blood for hemostasis; The Rhizoma Coptidis heat-clearing and toxic substances removing; Borneolum Syntheticum bitter cold, external nice and cool sense is arranged and can have one's ideas straightened out, heat clearing away, can reach rapid and persistent analgesic effect.The effect of whole medicine has heat clearing away, removing heat from blood, detoxifcation, analgesic effect.
More than form to be by weight as proportioning, when producing, can increase or reduce according to corresponding proportion, as large-scale production can be unit with the kilogram, or be unit with the ton, small-scale production can be unit with the milligram also, weight can increase or reduce, but the constant rate of the raw medicinal herbs weight proportion between each composition.
The raw material of Chinese medicine of said ratio extracts processing through new technology of the present invention, obtain the active constituents of medicine of preparation of the present invention, add suitable excipient as required and make suitable medicinal any dosage form, said preparation can be multiple suitable dosage forms such as capsule, granule, tablet, powder.
The specific embodiment:
Further specify the present invention by the following examples, include but not limited to the following example.
Embodiment 1
The preparation method of ointment of the present invention:
Prescription:
Radix Et Rhizoma Rhei 100g Radix Sanguisorbae 100g
Preparation method:
(1) get Radix Et Rhizoma Rhei, Radix Sanguisorbae medical material and soaked 30～90 minutes earlier with 50～95% ethanol, reheat reflux, extract, 2～6 times, each 0.5～3 hour, merge extractive liquid,, concentrating under reduced pressure becomes thick paste, and is standby.
(2) above active component is merged mixing, dry, be made into ointment according to the pharmaceutics routine techniques.
Embodiment 2
The preparation method of ointment of the present invention:
Prescription:
Radix Et Rhizoma Rhei 100g Radix Sanguisorbae 100g Rhizoma Coptidis 30g
Preparation method:
(1) get Radix Et Rhizoma Rhei, Radix Sanguisorbae, Rhizoma Coptidis medical material and soaked 30～90 minutes earlier with 50～95% ethanol, reheat reflux, extract, 2～6 times, each 0.5～3 hour, merge extractive liquid,, concentrating under reduced pressure becomes thick paste, and is standby;
(2) above active component is merged mixing, dry, be made into ointment according to the pharmaceutics routine techniques.
Embodiment 3
The preparation method of ointment of the present invention:
Prescription:
Radix Et Rhizoma Rhei 100g Radix Sanguisorbae 100g Borneolum Syntheticum 5g
Preparation method:
(1) get Radix Et Rhizoma Rhei, Radix Sanguisorbae medical material and soaked 30～90 minutes earlier with 50～95% ethanol, reheat reflux, extract, 2～6 times, each 0.5～3 hour, merge extractive liquid,, concentrating under reduced pressure becomes thick paste, and is standby.
(2) above active component is merged mixing, drying breaks into fine powder with Borneolum Syntheticum and adds wherein, is made into ointment according to the pharmaceutics routine techniques.
Embodiment 4
The preparation method of ointment of the present invention:
Prescription:
Radix Et Rhizoma Rhei 100g Radix Sanguisorbae 100g 80% ethanol
Preparation method:
(1) get Radix Et Rhizoma Rhei, Radix Sanguisorbae medical material and soaked 30～90 minutes earlier with 50～95% ethanol, reheat reflux, extract, 2～6 times, each 0.5～3 hour, merge extractive liquid,, concentrating under reduced pressure becomes thick paste, and is standby.
(2) above active component is merged mixing, drying, it is an amount of to add 80% ethanol, is made into ointment according to the pharmaceutics routine techniques.
Claims (8)
1, a kind of Chinese medicine preparation that is used for skin burn is characterized in that: according to weight proportion, it is by Radix Et Rhizoma Rhei 50～200, and Radix Sanguisorbae 50～200 is for basic side or be equipped with other Chinese medicines and generate the sides of deriving and be made.
2, the Chinese medicine preparation of claim 1 is characterized in that, described basic side's proportioning is: 100 parts of Radix Et Rhizoma Rhei, 100 parts of Radix Sanguisorbaes.
3, the Chinese medicine preparation of claim 1 is characterized in that, the proportioning of the described side of deriving is:
The basic side of A adds 30 parts of Rhizoma Coptidis
The basic side of B adds 5 parts of Borneolum Syntheticums
It is an amount of that the basic side of C adds 75%～95% ethanol.
4, the Chinese medicine preparation of claim 1 is characterized in that, is described raw material of Chinese medicine is extracted processing, obtains active component, adds suitable adjuvant as required, makes clinical needed dosage form with the galenic pharmacy routine techniques.
5, the Chinese medicine preparation of claim 4 is characterized in that:
The preparation process of described ointment is as follows: with above-mentioned extract obtained, add suitable substrate, can add wetting agent, antiseptic, antioxidant or transdermal enhancer in case of necessity and be prepared from.
6, the Chinese medicine preparation of claim 5 is characterized in that:
Described substrate comprises emulsion-type (soda soap, triethanolamine soap class, Polysorbate, lanoline, monoglyceride, aliphatic alcohol etc.), water solublity (Polyethylene Glycol), oil (vaseline, paraffin, liquid paraffin, silicone oil, Cera Flava, stearic acid etc.).
Suitable adjuvant comprises wherein one or more such as wetting agent, antiseptic, antioxidant, transdermal enhancer.
7, the preparation method of claim 6 is characterized in that: the prescription of the preparation of making is respectively:
The a Radix Et Rhizoma Rhei, Radix Sanguisorbae;
The b Radix Et Rhizoma Rhei, Radix Sanguisorbae, Rhizoma Coptidis;
The c Radix Et Rhizoma Rhei, Radix Sanguisorbae, Borneolum Syntheticum;
The d Radix Et Rhizoma Rhei, Radix Sanguisorbae, 75%～95% ethanol.
8, the Chinese medicine preparation of claim 1 is in preparation treatment skin scald, burn, the application in the medicine of diseases such as dermal viral herpes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610112873 CN1927293A (en) | 2006-09-06 | 2006-09-06 | Chinese medicine composition for treating skin burn and scald |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610112873 CN1927293A (en) | 2006-09-06 | 2006-09-06 | Chinese medicine composition for treating skin burn and scald |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1927293A true CN1927293A (en) | 2007-03-14 |
Family
ID=37857523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200610112873 Pending CN1927293A (en) | 2006-09-06 | 2006-09-06 | Chinese medicine composition for treating skin burn and scald |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1927293A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600363A (en) * | 2012-03-15 | 2012-07-25 | 沈慰平 | Traditional Chinese compound preparation for deep burnt wound restoration and tissue and skin regeneration promotion and preparation method of traditional Chinese compound preparation |
| CN103054975A (en) * | 2012-12-16 | 2013-04-24 | 蒋仕珍 | Chinese medicine for treating scald |
| CN103610814A (en) * | 2013-12-02 | 2014-03-05 | 王小欧 | Ointment for treating scald |
| CN105213733A (en) * | 2015-10-29 | 2016-01-06 | 青岛海之源智能技术有限公司 | A kind of wound repair Chinese medicine soap and preparation method thereof |
| CN109394866A (en) * | 2018-12-25 | 2019-03-01 | 西安医学院附属宝鸡医院 | A kind of necrosis removing and granulation promoting plaster and preparation method thereof |
| CN115645474A (en) * | 2022-07-22 | 2023-01-31 | 河南稷道数字栽培研究院有限公司 | Preparation method of aloe gel burn external use medicine |
-
2006
- 2006-09-06 CN CN 200610112873 patent/CN1927293A/en active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600363A (en) * | 2012-03-15 | 2012-07-25 | 沈慰平 | Traditional Chinese compound preparation for deep burnt wound restoration and tissue and skin regeneration promotion and preparation method of traditional Chinese compound preparation |
| CN102600363B (en) * | 2012-03-15 | 2014-03-19 | 沈慰平 | Traditional Chinese compound preparation for deep burnt wound restoration and tissue and skin regeneration promotion and preparation method of traditional Chinese compound preparation |
| CN103054975A (en) * | 2012-12-16 | 2013-04-24 | 蒋仕珍 | Chinese medicine for treating scald |
| CN103610814A (en) * | 2013-12-02 | 2014-03-05 | 王小欧 | Ointment for treating scald |
| CN103610814B (en) * | 2013-12-02 | 2015-06-03 | 王小欧 | Ointment for treating scald |
| CN105213733A (en) * | 2015-10-29 | 2016-01-06 | 青岛海之源智能技术有限公司 | A kind of wound repair Chinese medicine soap and preparation method thereof |
| CN109394866A (en) * | 2018-12-25 | 2019-03-01 | 西安医学院附属宝鸡医院 | A kind of necrosis removing and granulation promoting plaster and preparation method thereof |
| CN109394866B (en) * | 2018-12-25 | 2021-04-30 | 西安医学院附属宝鸡医院 | Paste for removing necrotic tissue and promoting tissue regeneration and preparation method thereof |
| CN115645474A (en) * | 2022-07-22 | 2023-01-31 | 河南稷道数字栽培研究院有限公司 | Preparation method of aloe gel burn external use medicine |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20070314 |