CN1586584A - Sinusitis capsule and its preparing method - Google Patents
Sinusitis capsule and its preparing method Download PDFInfo
- Publication number
- CN1586584A CN1586584A CN 200410069312 CN200410069312A CN1586584A CN 1586584 A CN1586584 A CN 1586584A CN 200410069312 CN200410069312 CN 200410069312 CN 200410069312 A CN200410069312 A CN 200410069312A CN 1586584 A CN1586584 A CN 1586584A
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- CN
- China
- Prior art keywords
- flos
- parts
- sinusitis
- radix rubiae
- fructus xanthii
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 201000009890 sinusitis Diseases 0.000 title claims abstract description 30
- 239000002775 capsule Substances 0.000 title claims abstract description 24
- 238000000034 method Methods 0.000 title claims description 11
- 241000628997 Flos Species 0.000 claims description 72
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 46
- 239000009670 cang er zi wan Substances 0.000 claims description 24
- 239000000706 filtrate Substances 0.000 claims description 17
- 239000000843 powder Substances 0.000 claims description 17
- 239000007788 liquid Substances 0.000 claims description 15
- 239000006071 cream Substances 0.000 claims description 13
- 238000004821 distillation Methods 0.000 claims description 10
- 239000000284 extract Substances 0.000 claims description 10
- 238000004519 manufacturing process Methods 0.000 claims description 10
- 239000000341 volatile oil Substances 0.000 claims description 10
- 241000245240 Lonicera Species 0.000 claims description 9
- 241000218378 Magnolia Species 0.000 claims description 9
- 239000012567 medical material Substances 0.000 claims description 8
- 238000005267 amalgamation Methods 0.000 claims description 7
- 229920001353 Dextrin Polymers 0.000 claims description 5
- 239000004375 Dextrin Substances 0.000 claims description 5
- 229920002472 Starch Polymers 0.000 claims description 5
- -1 after the dried Substances 0.000 claims description 5
- 235000019425 dextrin Nutrition 0.000 claims description 5
- 238000007598 dipping method Methods 0.000 claims description 5
- 239000008187 granular material Substances 0.000 claims description 5
- 239000012535 impurity Substances 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 238000005325 percolation Methods 0.000 claims description 5
- 239000002904 solvent Substances 0.000 claims description 5
- 239000007921 spray Substances 0.000 claims description 5
- 235000019698 starch Nutrition 0.000 claims description 5
- 239000008107 starch Substances 0.000 claims description 5
- 238000001256 steam distillation Methods 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 238000007789 sealing Methods 0.000 claims description 2
- 206010039083 rhinitis Diseases 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 8
- 241000123069 Ocyurus chrysurus Species 0.000 abstract description 4
- 201000009151 chronic rhinitis Diseases 0.000 abstract description 4
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 abstract 1
- 244000035851 Chrysanthemum leucanthemum Species 0.000 abstract 1
- 241000218394 Magnolia liliiflora Species 0.000 abstract 1
- 241001506766 Xanthium Species 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 239000013521 mastic Substances 0.000 description 9
- 239000003814 drug Substances 0.000 description 8
- 230000017531 blood circulation Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 229940079593 drug Drugs 0.000 description 3
- 238000006424 Flood reaction Methods 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 231100000915 pathological change Toxicity 0.000 description 2
- 230000036285 pathological change Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 206010009137 Chronic sinusitis Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010039085 Rhinitis allergic Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 201000010105 allergic rhinitis Diseases 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 208000027157 chronic rhinosinusitis Diseases 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 210000003695 paranasal sinus Anatomy 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
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- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The sinusitis capsule is prepared with cocklebur fruit in 64-82 weight portions, honeysuckle in 3-6 weight portions, wild chrysanthemum flower in 3-6 weight portions, lily magnolia in 9-12 weight portions and madder in 3-6 weight portions. The sinusitis capsule is for treating chronic rhinitis and nasosinusitis, and has high curative effect, no toxic side effect and no recurrence.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for the treatment of rhinitis, particularly a kind of sinusitis capsule for the treatment of chronic rhinitis and sinusitis.
Background technology
Rhinitis, sinusitis are otorhinolaryngologic commonly encountered diseases, frequently-occurring disease, belong to the traditional Chinese medical science " nasal sinusitis " category.Because the construction features of nasal sinuses portion has determined that nasal sinusitis is frequently-occurring disease, easily delay changes into chronic disease, and prolonged difficulty more.Chinese and western medicine is many with anti-inflammatory treatment both at home and abroad at present, such as " ' Biyanwan ' for treating rhinitis " that often use in the Chinese medicine, observes through clinical use, its curative effect is lower, and unstable, and for more serious patient, need impose the puncture flush operation, but effect is dissatisfied, normal easily recurrence, patient is difficult for accepting.
Summary of the invention
The objective of the invention is to: overcome deficiency of the prior art, a kind of chronic rhinitis, sinusitis of being used for the treatment of is provided, the curative effect height has no side effect, and cures prescription of the difficult sinusitis capsule that recurs in back and preparation method thereof.
The technical solution used in the present invention is: a kind of sinusitis capsule, and it is made up of Fructus Xanthii, Flos Lonicerae, Flos Chrysanthemi Indici, Flos Magnoliae, Radix Rubiae, and the compositing range of every kind of medical material is respectively: Fructus Xanthii 64-82 part; Flos Lonicerae 3-6 part; Flos Chrysanthemi Indici 3-6 part; Flos Magnoliae 9-18 part; Radix Rubiae 3-6 part.
In the sinusitis capsule compositing range of various medical materials can for: Fructus Xanthii is 72.70 parts; 4.55 parts of Flos Loniceraes; 4.55 parts of Flos Chrysanthemi Indicis; 13.65 parts of Flos Magnoliaes; 4.55 parts in Radix Rubiae.
The compositing range of various medical materials can be 64 parts of Fructus Xanthii in the sinusitis capsule; 6 parts of Flos Loniceraes; 6 parts of Flos Chrysanthemi Indicis; 18 parts of Flos Magnoliaes; 6 parts in Radix Rubiae.
The compositing range of various medical materials can be 82 parts of Fructus Xanthii in the sinusitis capsule; 3 parts of Flos Loniceraes; 3 parts of Flos Chrysanthemi Indicis; 9 parts of Flos Magnoliaes; 3 parts in Radix Rubiae.
Manufacture method to described sinusitis capsule comprises following steps:
(1) with Fructus Xanthii, Flos Lonicerae, Flos Chrysanthemi Indici, Flos Magnoliae, Radix Rubiae, remove impurity, it is standby to clean the back, and Radix Rubiae is ground into coarser powder.
(2) Flos Lonicerae, Flos Magnoliae, Flos Chrysanthemi Indici are added an amount of water, extract volatile oil with steam distillation, the solution for standby after the distillation.
(3) add Fructus Xanthii in the medicinal residues after said extracted, and add a certain amount of decocting and boil a period of time, decocting liquid is filtered.
(4) solution after the distillation in the filtrate that obtains in (3) and (2) is merged, and amalgamation liquid is condensed into cream, adding concentration in cream is the ethanol of 80%-96%, makes to contain the alcohol amount and reach 60%, stirs evenly then, leaves standstill, and filters, and collects filtrate for later use.
(5) be that the ethanol of 60%-80% is moistening with the Radix Rubiae powder with concentration, airtight placement a period of time, treat the moistening expansion of Radix Rubiae powder after, Radix Rubiae powder after will expanding is then packed in the percolator, ethanol with same concentration is made solvent, carries out percolation after dipping a period of time, collects percolate.
(6) percolate that obtains in the filtrate that obtains in (4) and (5) is merged, and be condensed into cream.
(7) in (6), obtain adding appropriate amount of starch or dextrin in the cream, evenly mixed, make granule, after the dried, spray into the volatile oil that extracts in (2), mixing incapsulates.
The manufacture method of described sinusitis capsule can be concentrated into amalgamation liquid relative density 1.10-1.30 (60-70 degree centigrade time survey) in (4) step.
The manufacture method of described sinusitis capsule can add concentration and be 95% ethanol in step (4).
The manufacture method of described sinusitis capsule can add concentration and be 70% ethanol in step (5), sealing can be 15-120 minute standing time, and the time of dipping can be 24 hours.
The manufacture method of described sinusitis capsule can be condensed into relative density and be the cream of 1.10-1.40 (60-70 degree centigrade time survey) after filtrate and percolate merge in step (6).
The mechanism of foundation of the present invention is: Fructus Xanthii is a monarch drug, bitter energy dampness, and gentle dredging reaches, and declares the network of promoting blood circulation, and can solely go up the top, mountain peak again, dredges the wind and cold of Naohu, is the key medicine of women's head-ornaments pathological changes, and clinical practice is in the main medicine of allergic rhinitis, chronic rhinitis, sinusitis; Flos Magnoliae is a ministerial drug, has the expelling pathogenic wind and restoring the functions of orifices in face effect, and it has inhibitory action to multiple pathogenic fungus modern study; Flos Lonicerae is to generally acknowledge effective broad-spectrum antiseptic, antiviral drugs, effectively treats the local infection symptom of rhinitis, removes pyretic toxicity Zhi Qiben; Flos Chrysanthemi Indici has wind and heat dispersing, and the effect of subduing swelling and detoxicating has significantly antibiotic, antivirus action, cures mainly the inflammation of respiratory tract; Radix Rubiae has the blood circulation promoting and blood stasis dispelling effect, can improve the partial blood circulation of pathological changes, promotes the recovery of local organization structural change.More than all medicines be used in combination, can the heat clearing away blood stasis dispelling, sensible invigorating blood circulation, treating both the principal and secondary aspects of a disease, and comprehensive functions such as antiinflammatory, antiallergic, adjusting immunologic function, analgesic, antiviral are arranged can be treated rhinitis, sinusitis comprehensively.
The specific embodiment
Embodiment one:
Get 6 parts in 18 portions of Radix Rubiaes of 6 parts of Flos Magnoliaes of 6 parts of Flos Chrysanthemi Indicis of 64 portions of Flos Loniceraes of Fructus Xanthii
(1), removes impurity, and Radix Rubiae is ground into 10-40 purpose coarser powder earlier with Fructus Xanthii, Flos Lonicerae, Flos Chrysanthemi Indici, Flos Magnoliae, Radix Rubiae.
(2) water of six times of amounts of adding in Flos Lonicerae, Flos Magnoliae, Flos Chrysanthemi Indici extracts volatile oil with steam distillation, the solution for standby after the distillation.
(3) add Fructus Xanthii in the medicinal residues after said extracted, and the decocting that adds four times of amounts boiled 3 hours, decocting liquid is poured out, the decocting that adds four times of amounts in medicinal residues again boiled 3 hours, merged decocting liquid twice, filtered then.
(4) solution after the distillation in the filtrate that obtains in (3) and (2) is merged, and amalgamation liquid is concentrated into relative density be 1.10 mastic of (60-70 degree centigrade time survey), the ethanol of adding 80% in this mastic, make the ethanol content in the solution reach 60%, stir evenly then, leave standstill, filter, collect filtrate for later use.
(5) with 60% ethanol that the Radix Rubiae powder is evenly moistening, airtight placement 120 minutes, the Radix Rubiae powder after will placing is then packed in the percolator, makes solvent with 60% ethanol, carries out percolation behind the dipping 24, collects percolate.
(6) percolate that obtains in the filtrate that obtains in (4) and (5) is merged, and be condensed into relative density be 1.10 mastic of (65-70 degree centigrade time survey).
(7) in (6), obtain adding appropriate amount of starch or dextrin in the cream, evenly mixed, make granule, after the dried, spray into the volatile oil that extracts in (2), mixing incapsulates, and adorns 0.5 gram for every.
Embodiment two:
Get 3 parts in 9 portions of Radix Rubiaes of 3 parts of Flos Magnoliaes of 3 parts of Flos Chrysanthemi Indicis of 82 portions of Flos Loniceraes of Fructus Xanthii
(1), removes impurity, and Radix Rubiae is ground into 10-40 purpose coarser powder earlier with Fructus Xanthii, Flos Lonicerae, Flos Chrysanthemi Indici, Flos Magnoliae, Radix Rubiae.
(2) water of 8 times of amounts of adding in Flos Lonicerae, Flos Magnoliae, Flos Chrysanthemi Indici extracts volatile oil with steam distillation, the solution for standby after the distillation.
(3) add Fructus Xanthii in the medicinal residues after said extracted, and the decocting that adds 8 times of amounts boiled 3 hours, decocting liquid is poured out, the decocting that adds 8 times of amounts in medicinal residues again boiled 3 hours, merged decocting liquid twice, filtered then.
(4) solution after the distillation in the filtrate that obtains in (3) and (2) is merged, and amalgamation liquid is concentrated into relative density be 1.30 mastic of (60-70 degree centigrade time survey), the ethanol of adding 96% in this mastic, make the ethanol content in the solution reach 60%, stir evenly then, leave standstill, filter, collect filtrate for later use.
(5) with 80% ethanol that the Radix Rubiae powder is evenly moistening, airtight placement 15 minutes, the Radix Rubiae powder after will placing is then packed in the percolator, makes solvent with 80% ethanol, floods and carries out percolation after 24 hours, collects percolate.
(6) percolate that obtains in the filtrate that obtains in (4) and (5) is merged, and be condensed into relative density be 1.40 mastic of (65-70 degree centigrade time survey).
(7) in (6), obtain adding appropriate amount of starch or dextrin in the cream, evenly mixed, make granule, after the dried, spray into the volatile oil that extracts in (2), mixing incapsulates, and adorns 0.5 gram for every.
Embodiment three (most preferred embodiment):
Get 4.55 parts in 13.65 portions of Radix Rubiaes of 4.55 parts of Flos Magnoliaes of 4.55 parts of Flos Chrysanthemi Indicis of 72.7 portions of Flos Loniceraes of Fructus Xanthii
(1), removes impurity, and Radix Rubiae is ground into 10-40 purpose coarser powder earlier with Fructus Xanthii, Flos Lonicerae, Flos Chrysanthemi Indici, Flos Magnoliae, Radix Rubiae.
(2) water of 6 times of amounts of adding in Flos Lonicerae, Flos Magnoliae, Flos Chrysanthemi Indici extracts volatile oil with steam distillation, the solution for standby after the distillation.
(3) add Fructus Xanthii in the medicinal residues after said extracted, and the decocting that adds 6 times of amounts boiled 3 hours, decocting liquid is poured out, the decocting that adds 8 times of amounts in medicinal residues again boiled 3 hours, merged decocting liquid twice, filtered then.
(4) solution after the distillation in the filtrate that obtains in (3) and (2) is merged, and amalgamation liquid is concentrated into relative density be 1.30 mastic of (60-70 degree centigrade time survey), the ethanol of adding 95% in this mastic, make the ethanol content in the solution reach 60%, stir evenly then, leave standstill, filter, collect filtrate for later use.
(5) with 70% ethanol that the Radix Rubiae powder is evenly moistening, airtight placement 60 minutes, the Radix Rubiae powder after will placing is then packed in the percolator, makes solvent with 70% ethanol, floods and carries out percolation after 24 hours, collects percolate.
(6) percolate that obtains in the filtrate that obtains in (4) and (5) is merged, and be condensed into relative density be 1.30 mastic of (65-70 degree centigrade time survey).
(7) in (6), obtain adding appropriate amount of starch or dextrin in the cream, evenly mixed, make granule, after the dried, spray into the volatile oil that extracts in (2), mixing incapsulates, and adorns 0.5 gram for every.
Claims (9)
1, a kind of sinusitis capsule is characterized in that: it is made up of Fructus Xanthii, Flos Lonicerae, Flos Chrysanthemi Indici, Flos Magnoliae, Radix Rubiae, and the compositing range of every kind of medical material is respectively: Fructus Xanthii 64-82 part; Flos Lonicerae 3-6 part; Flos Chrysanthemi Indici 3-6 part; Flos Magnoliae 9-18 part; Radix Rubiae 3-6 part.
2, sinusitis capsule according to claim 1 is characterized in that: the compositing range of various medical materials is: 72.70 parts of Fructus Xanthii; 4.55 parts of Flos Loniceraes; 4.55 parts of Flos Chrysanthemi Indicis; 13.65 parts of Flos Magnoliaes; 4.55 parts in Radix Rubiae.
3, sinusitis capsule according to claim 1 is characterized in that: the compositing range of various medical materials is: 64 parts of Fructus Xanthii; 6 parts of Flos Loniceraes; 6 parts of Flos Chrysanthemi Indicis; 18 parts of Flos Magnoliaes; 6 parts in Radix Rubiae.
4, sinusitis capsule according to claim 1 is characterized in that: the compositing range of various medical materials is: 82 parts of Fructus Xanthii; 3 parts of Flos Loniceraes; 3 parts of Flos Chrysanthemi Indicis; 9 parts of Flos Magnoliaes; 3 parts in Radix Rubiae.
5, the manufacture method of 1 described sinusitis capsule as requested, it is characterized in that: it comprises following steps:
(1) with Fructus Xanthii, Flos Lonicerae, Flos Chrysanthemi Indici, Flos Magnoliae, Radix Rubiae, remove impurity, it is standby to clean the back, and Radix Rubiae is ground into coarser powder.
(2) Flos Lonicerae, Flos Magnoliae, Flos Chrysanthemi Indici are added an amount of water, extract volatile oil with steam distillation, the solution for standby after the distillation.
(3) add Fructus Xanthii in the medicinal residues after said extracted, and add a certain amount of decocting and boil a period of time, decocting liquid is filtered.
(4) solution after the distillation in the filtrate that obtains in (3) and (2) is merged, and amalgamation liquid is condensed into cream, adding concentration in cream is the ethanol of 80%-96%, makes to contain the alcohol amount and reach 60%, stirs evenly then, leaves standstill, and filters, and collects filtrate for later use.
(5) be that the ethanol of 60%-80% is moistening with the Radix Rubiae powder with concentration, airtight placement a period of time, treat the moistening expansion of Radix Rubiae powder after, Radix Rubiae powder after will expanding is then packed in the percolator, ethanol with same concentration is made solvent, carries out percolation after dipping a period of time, collects percolate.
(6) percolate that obtains in the filtrate that obtains in (4) and (5) is merged, and be condensed into cream.
(7) in (6), obtain adding appropriate amount of starch or dextrin in the cream, evenly mixed, make granule, after the dried, spray into the volatile oil that extracts in (2), mixing incapsulates.
6, the manufacture method of sinusitis capsule according to claim 5 is characterized in that: in (4) step, amalgamation liquid is concentrated into relative density 1.10-1.30 (60-70 degree centigrade time survey).
7, the manufacture method of sinusitis capsule according to claim 6 is characterized in that: adding concentration is 95% ethanol in step (4).
8, the manufacture method of sinusitis capsule according to claim 7 is characterized in that: adding concentration is 70% ethanol in step (5), and sealing standing time is 15-120 minute, and the time of dipping is 24 hours.
9, the manufacture method of sinusitis capsule according to claim 8 is characterized in that: the cream that is condensed into relative density after filtrate and percolate merge in step (6) and is 1.10-1.40 (60-70 degree centigrade time survey).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410069312 CN1586584A (en) | 2004-07-16 | 2004-07-16 | Sinusitis capsule and its preparing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410069312 CN1586584A (en) | 2004-07-16 | 2004-07-16 | Sinusitis capsule and its preparing method |
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| Publication Number | Publication Date |
|---|---|
| CN1586584A true CN1586584A (en) | 2005-03-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410069312 Pending CN1586584A (en) | 2004-07-16 | 2004-07-16 | Sinusitis capsule and its preparing method |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1958003B (en) * | 2005-10-31 | 2011-04-13 | 北京奇源益德药物研究所 | Preparation for treating chronic nasosinusitis, preparation method and quality control method |
| CN101543545B (en) * | 2008-03-28 | 2011-05-25 | 北京亚东生物制药有限公司 | Traditional Chinese medicine preparation for curing rhinitis and quality control method thereof |
| CN106309638A (en) * | 2016-08-28 | 2017-01-11 | 福州海王金象中药制药有限公司 | Nasosinusitis capsule preparation technology |
| CN106728146A (en) * | 2017-02-13 | 2017-05-31 | 佛山市腾瑞医药科技有限公司 | A kind of Chinese medicine for treating rhinitis composition and preparation method thereof |
-
2004
- 2004-07-16 CN CN 200410069312 patent/CN1586584A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1958003B (en) * | 2005-10-31 | 2011-04-13 | 北京奇源益德药物研究所 | Preparation for treating chronic nasosinusitis, preparation method and quality control method |
| CN101543545B (en) * | 2008-03-28 | 2011-05-25 | 北京亚东生物制药有限公司 | Traditional Chinese medicine preparation for curing rhinitis and quality control method thereof |
| CN106309638A (en) * | 2016-08-28 | 2017-01-11 | 福州海王金象中药制药有限公司 | Nasosinusitis capsule preparation technology |
| CN106728146A (en) * | 2017-02-13 | 2017-05-31 | 佛山市腾瑞医药科技有限公司 | A kind of Chinese medicine for treating rhinitis composition and preparation method thereof |
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