CN1788754A - Oral medicine for treating hyperosteogeny-pellet for treating bone pain - Google Patents
Oral medicine for treating hyperosteogeny-pellet for treating bone pain Download PDFInfo
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- CN1788754A CN1788754A CN 200410064599 CN200410064599A CN1788754A CN 1788754 A CN1788754 A CN 1788754A CN 200410064599 CN200410064599 CN 200410064599 CN 200410064599 A CN200410064599 A CN 200410064599A CN 1788754 A CN1788754 A CN 1788754A
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- radix
- hyperosteogeny
- treating
- pellet
- oral medicine
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- 206010005963 Bone formation increased Diseases 0.000 title claims abstract description 18
- 239000003814 drug Substances 0.000 title claims abstract description 15
- 206010006002 Bone pain Diseases 0.000 title claims description 6
- 239000008188 pellet Substances 0.000 title claims description 6
- 241000903946 Clematidis Species 0.000 claims description 9
- 210000004185 liver Anatomy 0.000 abstract description 10
- 210000003734 kidney Anatomy 0.000 abstract description 9
- 210000000988 bone and bone Anatomy 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 7
- 210000002435 tendon Anatomy 0.000 abstract description 3
- 244000061520 Angelica archangelica Species 0.000 abstract 1
- 241000218158 Clematis Species 0.000 abstract 1
- 241000893536 Epimedium Species 0.000 abstract 1
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 235000018905 epimedium Nutrition 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 7
- 210000003205 muscle Anatomy 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 3
- 230000007812 deficiency Effects 0.000 description 3
- 208000037920 primary disease Diseases 0.000 description 3
- 238000005728 strengthening Methods 0.000 description 3
- 210000002805 bone matrix Anatomy 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 206010020718 hyperplasia Diseases 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 206010002556 Ankylosing Spondylitis Diseases 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 239000003390 Chinese drug Substances 0.000 description 1
- 241000005787 Cistanche Species 0.000 description 1
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 206010024452 Ligament laxity Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 230000008468 bone growth Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000005786 degenerative changes Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 201000008482 osteoarthritis Diseases 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to one kind of oral medicine for treating hyperosteogeny named as Gutongdan pill. The medicine is prepared with prepared rhizome of rehmannia 10-30 weight portions, epimedium 5-20 weight portions, angelica 10-30 weight portions clematis root 5-15 weight portions. The present invention has the functions of expelling wind evil, dispersing cold and eliminating wetness. Based on the theory of 'the kidney is in charge of bones and the liver is in charge of tendons', the present invention has increased liver and kidney benefiting medicine components for treating the primary causes, so that it has obviously raised curative effect on hyperosteogeny.
Description
Hyperosteogeny is a kind of chronic progressive external osteoarthritis of serious harm middle-aged and elderly people health, studies according to postmortem: the people was since 20 years old, and just there is degenerative change in the joint; During by 40 years old, almost 90% the people joint of bearing a heavy burden all has hypertrophy more or less to change.Though primary disease threatens patient's life unlike tumor, disability rate is also so high unlike rheumatoid arthritis, ankylosing spondylitis, but because of the prevalence height, long-term discomfort and dysfunction can not be underestimated the influence of patient quality of life due to it, step into aging society and old people's rapid increase along with China, the number of the infected of hyperosteogeny will rise thereupon, at present, left and right sides crowd had 25% people to suffer from this disease approximately in 50 years old, people Ze Da 50% about 60 years old, people about 70 years old reaches 100%, and the people's health in serious threat.Therefore, how to improve the curative effect of primary disease, reduce patient's misery and disability rate, become the focus of domestic and international research.Chinese patent application has been announced a kind of " hyperosteogeny is taken Chinese patent medicine orally " number No. 03135341, it is made up of Herba Epimedii, Radix Rehmanniae Preparata, Herba Cistanches, Huaihe River Fructus Psoraleae, Fructus Lycii, Caulis Spatholobi, Radix Salviae Miltiorrhizae, Cornu Cervi tablet, Rhizoma Cibotii, the Cortex Eucommiae, Radix Polygoni Multiflori, is used for treating hyperosteogeny.
Summary of the invention
Purpose of the present invention provides a kind of oral medicine for the treatment of hyperosteogeny---pellet for treating bone pain.
The present invention is achieved through the following technical solutions:
1, make by following components by weight portion:
Radix Rehmanniae Preparata (10-30) part, Herba Epimedii (5-20) part, Radix Angelicae Sinensis (10-30) part, Radix Aconiti Preparata (3-12) part and Radix Clematidis (5-15) part.
2, make by the optimum ratio of following ratio of weight and number:
Radix Rehmanniae Preparata (15-25) part, Herba Epimedii (5-15) part, Radix Angelicae Sinensis (12-20) part, Radix Aconiti Preparata (3-10) part and Radix Clematidis (6-12) part.
3, make by the proportioning component of following the best:
10 parts of 30 parts of Radix Rehmanniae Preparata, 20 parts of Herba Epimedii, 12 parts of Radix Angelicae Sinensis, 6 parts of Radix Aconiti Preparatas and Radix Clematidis.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to " rheumatism involving the bone ", wet by invigorating the liver and kidney, strengthening bone and muscle, blood circulation promoting and blood stasis dispelling, removing cold and wind with reference to the modern pharmacology achievement in research, treats hyperosteogeny.According to theory of Chinese medical science, hyperosteogeny belongs to the category of the traditional Chinese medical science " rheumatism involving the bone ".Deficiency of the liver and kindey, essence and blood loss are the basic reasons that bone matrix hyperplasia takes place.The people is to person in middle and old age, the Liver and kidney degradation, and the essence and blood loss, suffering from a deficiency of the kidney is difficult bone strengthening, and deficiency of the liver is difficult nourishing muscle and tendon, and the not hard then vertebra of bone bone growth promoting thorn, muscle are not supported then laxity of ligament, and wind-cold damp pathogen is taken advantage of a weak point, and it is not smooth to cause QI-blood circulation, " stagnation of QI and blood may bring about pain ", and primary disease takes place.Radix Rehmanniae Preparata, Herba Epimedii, Radix Angelicae Sinensis in the side, liver and kidney tonifying negative and positive essence and blood improves body resistance against diseases, makes and just wins heresy, to effect a permanent cure; Radix Aconiti Preparata, Radix Clematidis are dispeled wind, cold, damp, the meridian dredging, and stopping numbness pain is to take stopgap measures.Each component combination, energy invigorating the liver and kidney, strengthening bone and muscle, the exopathogen of dispelling, the meridian dredging, it is suitable that QI and blood is transferred, and arthralgia pain is from removing.
Advantage of the present invention is that the effect of treatment hyperosteogeny is obvious.Reason is that the present invention is on the basis of traditional Chinese medical science tradition method of treatment " dispel the wind, cold expelling, dehumidifying ", according to the theory of " kidney governing bones ", " liver governing tendons ", has increased the weight of the medicine of liver and kidney tonifying negative and positive essence and blood with " effecting a permanent cure ", and curative effect is obviously improved.
For showing the curative effect of Chinese medicine of the present invention, through the external service department of Provincial Medicine Research Institute, Hebei traditional Chinese medical science osteopathia treatment bone matrix hyperplasia 62 examples, knee joint hyperosteogeny 15 examples wherein, cervical vertebra hyperosteogeny 26 examples, joint of lumbar vertebra hyperosteogeny 21 examples.Treat after 1 month clinical cure 30 examples, 12 examples that significantly take a turn for the better, 17 examples that take a turn for the better, invalid 3 examples.Total effective rate is 95.2%.
Embodiments of the present invention are as follows:
| Component | Implement 1 | Implement 2 | Implement 3 | Implement 4 | Implement 5 | Implement 6 | Implement 7 |
| Radix Rehmanniae Preparata | 10g | 20g | 30g | 15g | 20g | 25g | 30g |
| Herba Epimedii | 20g | 12g | 5g | 15g | 10g | 5g | 20g |
| Radix Angelicae Sinensis | 10g | 20g | 30g | 20g | 16g | 12g | 12g |
| Radix Aconiti Preparata | 12g | 9g | 3g | 3g | 7g | 10g | 6g |
| Radix Clematidis | 5g | 10g | 15g | 12g | 9g | 6g | 10g |
The production method that above-mentioned each component is made Chinese medicine of the present invention is:
Get Radix Rehmanniae Preparata, Herba Epimedii, Radix Angelicae Sinensis, Radix Aconiti Preparata, Radix Clematidis, mix, be soaked in water 2-4 hour, extract 3 times with the decocting extraction method, each time all used slow fire boiling 1-2 hour, with 3 decocting liquid mixing, concentrated, dry, promptly obtains finished product.
Utilize respectively component of the present invention, make said any oral medicine dosage form on the pharmaceutics of Chinese drugs, all can play same effect.
Claims (3)
1, a kind of oral medicine for the treatment of hyperosteogeny---pellet for treating bone pain is characterized in that it is made by following components by weight portion: Radix Rehmanniae Preparata (10-30) part, Herba Epimedii (5-20) part, Radix Angelicae Sinensis (10-30) part, Radix Aconiti Preparata (3-12) part and Radix Clematidis (5-15) part.
2, a kind of oral medicine for the treatment of hyperosteogeny according to claim 1---pellet for treating bone pain is characterized in that it is made by the optimum ratio of following ratio of weight and number: Radix Rehmanniae Preparata (15-25) part, Herba Epimedii (5-15) part, Radix Angelicae Sinensis (12-20) part, Radix Aconiti Preparata (3-10) part and Radix Clematidis (6-12) part.
3, a kind of oral medicine for the treatment of hyperosteogeny according to claim 1 and 2---pellet for treating bone pain is characterized in that it is made by the proportioning component of following the best: 10 parts of 30 parts of Radix Rehmanniae Preparata, 20 parts of Herba Epimedii, 12 parts of Radix Angelicae Sinensis, 6 parts of Radix Aconiti Preparatas and Radix Clematidis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410064599 CN1788754A (en) | 2004-12-13 | 2004-12-13 | Oral medicine for treating hyperosteogeny-pellet for treating bone pain |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410064599 CN1788754A (en) | 2004-12-13 | 2004-12-13 | Oral medicine for treating hyperosteogeny-pellet for treating bone pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1788754A true CN1788754A (en) | 2006-06-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410064599 Pending CN1788754A (en) | 2004-12-13 | 2004-12-13 | Oral medicine for treating hyperosteogeny-pellet for treating bone pain |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103550380A (en) * | 2013-11-15 | 2014-02-05 | 王楚霄 | Traditional Chinese medicine composition for treating hyperostosis |
| CN105395754A (en) * | 2015-11-30 | 2016-03-16 | 马瑞 | Internal medicine for treating osteoproliferation |
| CN106511831A (en) * | 2016-12-06 | 2017-03-22 | 车念祖 | Traditional Chinese medicine composition for treating cervical spondylosis and lumbar spondylosis |
| CN108888680A (en) * | 2018-09-26 | 2018-11-27 | 丁武沛 | A kind of Chinese medicine for treating liver-kidney yin deficiency osteoproliferation |
| CN118059165B (en) * | 2024-02-29 | 2025-06-20 | 贵州中医药大学第二附属医院 | Medicine for treating knee osteoarthritis, preparation method and application |
-
2004
- 2004-12-13 CN CN 200410064599 patent/CN1788754A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103550380A (en) * | 2013-11-15 | 2014-02-05 | 王楚霄 | Traditional Chinese medicine composition for treating hyperostosis |
| CN103550380B (en) * | 2013-11-15 | 2015-07-08 | 王楚霄 | Traditional Chinese medicine composition for treating hyperostosis |
| CN105395754A (en) * | 2015-11-30 | 2016-03-16 | 马瑞 | Internal medicine for treating osteoproliferation |
| CN106511831A (en) * | 2016-12-06 | 2017-03-22 | 车念祖 | Traditional Chinese medicine composition for treating cervical spondylosis and lumbar spondylosis |
| CN108888680A (en) * | 2018-09-26 | 2018-11-27 | 丁武沛 | A kind of Chinese medicine for treating liver-kidney yin deficiency osteoproliferation |
| CN118059165B (en) * | 2024-02-29 | 2025-06-20 | 贵州中医药大学第二附属医院 | Medicine for treating knee osteoarthritis, preparation method and application |
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| WD01 | Invention patent application deemed withdrawn after publication |