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CN1241602C - Oral administered medicated wine for treating cardiovascular and cerebrovascular diseases - Google Patents

Oral administered medicated wine for treating cardiovascular and cerebrovascular diseases Download PDF

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CN1241602C
CN1241602C CNB2004100121197A CN200410012119A CN1241602C CN 1241602 C CN1241602 C CN 1241602C CN B2004100121197 A CNB2004100121197 A CN B2004100121197A CN 200410012119 A CN200410012119 A CN 200410012119A CN 1241602 C CN1241602 C CN 1241602C
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CN1557371A (en
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王根文
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Abstract

The present invention relates to a medicinal liqueur for treating coronary heart disease, hyperlipoidemia, hypertension, cerebral thrombosis and other cardiovascular and cerebrovascular diseases. The medicinal liqueur is prepared from angelica, prepared rhizome of rehmannia, white paeony root, himalayan teasel root, psoralea fruit, clematis root, Chinese flowering quince, reticulate millettia, twotooth achyranthes root, ledebouriella root, Saint Paul's-wort, Chuanxiong rhizome, india madder root, red sage root, decumbent bugle herb, great burdock achene, rhizome of drynaria, pubescent angelica root, epimedium herb, tremolite or tremolite asbestos, cortex acanthopanacis, Chinese yam, eucommia bark, pueraria root, fleece flower root, safflower, glossy ganoderma, pangolin scales, flos caryophyllata, scorpion, wild ginger, kusnezoff monkshood root, and 30 to 60% of white spirit as the rest measured by weight. The medicinal liqueur of the present invention is not treated by high temperature, so the original components of cells of all traditional Chinese medicines are guaranteed; oxygen and potency of the medicine quickly reach all the positions of the body under the action of the medicinal liqueur, and the obvious effect of medicine treatment is enhanced; the medicinal liqueur is taken 5 to 10 ml every time, so the taking dose is small; the medicinal liqueur is taken every day both in the morning and in the evening in winter and summer on an empty stomach, so the medicinal liqueur is convenient to take.

Description

The oral medicinal liquor of treatment cardiovascular and cerebrovascular disease
Technical field
The present invention relates to a kind of medicated wine for the treatment of cardiovascular and cerebrovascular diseases such as coronary heart disease, hyperlipidemia, hypertension, cerebral thrombosis, specifically is the medicinal preparation for oral administration that 32 kinds of Chinese herbal medicine of a kind of usefulness and soaking in Chinese liquor form.
Background technology
Cardiovascular and cerebrovascular disease is the universality disease of serious harm human health, and sharply increases year by year, and mortality rate and to the height of residual rate is referred to as the first killer of human health.
Domestic at present a lot of to the medicine for the treatment of this type of disease, but also have certain weak point, such as, the just simple blood pressure lowering of antihypertensive drugs, blood circulation promoting medicine is just invigorated blood circulation merely, the just simple blood vessel dilating of blood vessel dilating, that enriches blood just enriches blood merely.After comprehensive the use, the generation of many side effect is often arranged, and after the treatment, the very fast bounce-back of the state of an illness makes patient form dependency to medicine, even feels to live in the edge of life.In addition, it is 97103888.0 that Chinese patent also discloses a kind of patent No., and name is called " a kind of manufacture method of heart and brain recovery function medicated wine ", this medicated wine Chinese herbal medicine is kind more than 60 nearly, so the multiple medicines thing is immersed in together, influences the performance of principal agent effect, and is also not good to the curative effect of treatment cardiovascular and cerebrovascular disease; And spell out and help treating cardio-cerebral diseases in its summary, that is to say not reach clear and definite curative effect.
Summary of the invention
The present invention realizes by following scheme, and the oral medicinal liquor of treatment cardiovascular and cerebrovascular disease is that the preparation of raw material by following weight ratio forms,
Radix Angelicae Sinensis 6-13 part Radix Rehmanniae Preparata 6-13 part Radix Paeoniae Alba 6-13 part Radix Dipsaci 6-13 part
Fructus Psoraleae 6-13 part Radix Clematidis 6-13 part Fructus Chaenomelis 6-13 part Caulis Spatholobi 6-13 part
Radix Achyranthis Bidentatae 6-13 part Radix Saposhnikoviae 6-13 part Radix Rubiae 6-13 part Herba Siegesbeckiae 6-13 part
Radix Salviae Miltiorrhizae 3-13 part Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 6-13 part Rhizoma Chuanxiong 3-13 part Fructus Arctii 6-13 part
Rhizoma Drynariae 3-10 part Radix Angelicae Pubescentis 3-10 part Herba Epimedii 3-10 part Actinolitum 3-10 part
Cortex Acanthopancis 6-13 part Rhizoma Dioscoreae 6-15 part Cortex Eucommiae 6-15 part Radix Puerariae 6-15 part
Radix Polygoni Multiflori 10-15 part Flos Carthami 3-6 part Ganoderma lucidum seu Japonicum 6-10 part Squama Manis 3-10 part
Flos Caryophylli 1-3 part Scorpio 3-10 part Herba Asari 2-3 part Radix Aconiti Kusnezoffii 1.5-3 part;
Surplus is that alcoholic strength is the oleo stock Chinese liquor of 30-60%.
The present invention treats the oral medicinal liquor of cardiovascular and cerebrovascular disease, is that the preparation of raw material by following weight ratio forms,
13 parts of 13 parts of Radix Dipsacis of 13 portions of Radix Paeoniae Albas of 13 parts of Radix Rehmanniaes Preparata of Radix Angelicae Sinensis
13 parts of 13 portions of Caulis Spatholobis of 13 portions of Fructus Chaenomeliss of 13 parts of Radix Clematidis of Fructus Psoraleae
13 parts of 13 parts of Herba Siegesbeckiae of 13 portions of Radix Rubiaes of 13 parts of Radix Saposhnikoviaes of Radix Achyranthis Bidentatae
13 parts of 13 parts of Fructus Arctiis of 13 parts of Rhizoma Chuanxiongs of 13 parts of Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.)s of Radix Salviae Miltiorrhizae
10 parts of 10 parts of Actinolitum of 10 parts of Herba Epimedii of 10 parts of Radix Angelicae Pubescentiss of Rhizoma Drynariae
15 parts of 15 parts of Radix Puerariaes of 15 parts of Cortexs Eucommiae of 13 portions of Rhizoma Dioscoreaes of Cortex Acanthopancis
3 parts of 6 parts of Squama Maniss of 6 portions of Ganoderma lucidum seu Japonicumes of 15 parts of Flos Carthamis of the Radix Polygoni Multiflori
1.5 parts of 1.5 portions of Radix Aconiti Kusnezoffii of 3 parts of Herba Asaris of 3 portions of Scorpios of Flos Caryophylli;
Surplus is that alcoholic strength is 38% oleo stock Chinese liquor.
The pharmacology that the present invention treats cardiovascular and cerebrovascular disease is divided into following a few part:
1, the class medicine that induces sweat:
Principal agent: Radix Saposhnikoviae, go into liver, lung, taste, bladder, wind-damp dispelling, relieving the exterior syndrome by diaphoresis; Herba Asari is gone into the heart, liver, kidney, the wind-getting resuscitation that looses, and anemofrigid-damp arthralgia has analgesic activity; Scorpio, expelling pathogenic wind from the body surface, the diffusing numbness of arresting convulsion; Radix Puerariae is gone into the taste large intestine, and diaphoresis is brought down a fever, and antidiarrheal is quenched the thirst, and analgesic activity is arranged, and Radix Puerariae has the expansion cerebral arteries again, cerebral blood flow increasing amount, the excretory effect of excited glandula.
Accessory drugs: Fructus Arctii, go into the lung stomach, lung moistening is purged heat, and it is swollen analgesic to loose, and the function of detoxification of reducing phlegm is arranged, and diuresis is arranged; Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), heat-clearing and toxic substances removing, reducing swelling and alleviating pain, the removing heat from blood suppressing the hyperactive liver has diuresis, enhancing human body immunity power.
2, wind-expelling pain-stopping class medicine:
Principal agent: Radix Angelicae Pubescentis, go into liver, kidney, relieving the exterior syndrome by diaphoresis, rheumatic arthralgia has arthritis, blood vessel dilating, the effect of blood pressure lowering; Radix Clematidis is gone into urinary bladder channel, dispels the wind and is open to the custom, and alleviating pain and detumescence has diuresis, blood pressure lowering, spread spectrum antibacterial action; Caulis Spatholobi, function be enrich blood, promoting the circulation of blood, soothing the channels and quicking the network vessels, the effect of the blood pressure lowering of enriching blood is arranged; Herba Siegesbeckiae, wind-damp dispelling, the collateral dredging blood pressure lowering cures mainly rheumatic arthritis, numb limbs and tense tendons, hypertension.
Accessory drugs: Cortex Acanthopancis, go into liver, kidney, expelling wind and dampness, the strong muscle of tonify deficiency has arthritis, and analgesic activity energy enhancing body is to the resistance of disease; Radix Aconiti Kusnezoffii goes into 12 warps, the wind pain relieving of loosing, rheumatism contracture; Fructus Chaenomelis goes into spleen, stomach, liver, lung, the relieving rigidity of muscles and joints wind-damp dispelling.
3, the blood class medicine of regulating the flow of vital energy:
Principal agent: Radix Salviae Miltiorrhizae, go into the heart, liver, benefiting QI for activating blood circulation, the blood stasis removing pain relieving has analgesia, blood pressure lowering, bacteriostasis; Flos Carthami is gone into the heart, liver, and removing blood stasis is invigorated blood circulation, reducing swelling and alleviating pain, and hypotensive effect is arranged, and Rhizoma Chuanxiong is gone into liver, gallbladder, heart born of the same parents, pleasant, circulation of qi promoting, and removing blood stasis with potent drugs is supported new, and hypotensive effect is arranged; Radix Angelicae Sinensis is gone into the heart, liver, spleen, enriches blood, and warming middle-JIAO to relieve pain is moisturized laxation, removing blood stasis to promote tissue regeneration; Radix Rubiae goes into liver, meridians, blood stasis removing pain relieving, the hemostasis of bringing down a fever.
Accessory drugs: Radix Achyranthis Bidentatae, go into liver, kidney, it is descending to draw all medicines, and the effect of blood stasis removing and clots absorbing is arranged, and of short duration blood pressure lowering and the effect of slight diarrhea urine are arranged; Squama Manis is gone into liver, stomach, the blood collateral dredging that looses, the evacuation of pus of merit skin ulcer.
4, tonic class medicine:
Principal agent: the Cortex Eucommiae, go into liver, kidney, the tonifying liver warming the stomach, strong muscle is antiabortive, and blood pressure lowering, diuresis are arranged; Radix Dipsaci is gone into liver, kidney, liver and kidney tonifying, continuous muscle pain relieving, promoting blood circulation, sharp joint; Pain relieving, granulation promoting, benefit is smart antiabortive, contains vitamin E; Fructus Psoraleae is gone into spleen, kidney, heart born of the same parents, warm lumbus and tonifying kidney, and strong muscles and bones has coronary artery dilator and bacteriostasis; Rhizoma Drynariae is gone into liver, kidney, the promoting the circulation of blood hemostasis, and strong muscle is enriched blood supplementing the kidney to control the nocturnal; Radix Rehmanniae Preparata is gone into the heart, lung, kidney, nourishing kidney-YIN, blood enriching and generation of vital essence promoting; Radix Polygoni Multiflori, tonifying liver, nourishing kidney, the strong muscle that nourishes blood can promote the new life of hemocyte to grow, and stops cholesterol at intrahepatic deposition, and the effect of excited intestinal smooth muscle is arranged; Herba Epimedii, warming the kidney to invigorate YANG, blood pressure lowering, the diastole peripheral vessels is built up resistance.
Accessory drugs: Rhizoma Dioscoreae, go into spleen, stomach, lung, kidney, clearind deficient heat, strengthening the spleen and stomach is held up weakness; The Radix Paeoniae Alba goes into liver, spleen, lung, the yin fluid astringing that nourishes blood, and eliminating pathogen in the liver peace spleen, sharp intestinal of heat clearing away and the diffusing what of blood have the spread spectrum antibacterial action; Ganoderma lucidum seu Japonicum, the effect of strengthening by means of tonics; Actinolitum, invigorate vital energy and yang; Flos Caryophylli goes into lung, kidney, stomach, spleen, and warming the spleen warms up waist, and tonifying YANG antidiarrheal has the promotion gastric secretion, the function of stimulating intestine and stomach wriggling.
Alcoholic strength is the oleo stock Chinese liquor of 30-60%, provides approach for each organ of human body absorbs oxygen rapidly.
Above-mentioned each component is adopted following method preparation:
A, take by weighing each dry Chinese medicine mixing, be ground into 100 orders in its ratio;
B, soak 80g medicated powder by the 500ml wine liquid and take by weighing (alcoholic strength is about 30-60%); Soaking 400g medicated powder with the 2500ml wine liquid is a course of treatment.
C, immersion are poured medicated powder in jar or the glass container into, slowly add Chinese liquor, and stir with Glass rod or wooden stick, and fully fusion seals, and is stirred in the immersion;
D, extraction were soaked after 60 days, fully stirred again, after the clarification, poured out supernatant, again with medicinal residues with pressing bean curd method elimination medicinal liquid, mixes with supernatant, disgorging pours into supernatant in the disinfectant bottle, seals, packs and get final product with aseptic manipulation.
The present invention is according to tcm treatment according to syndrome differentiation, and human body is carried out comprehensively regulating, and the unification of the recurrence relation of cardiovascular and cerebrovascular disease and rheumatism and human body integral opinion idea.During according to the treatment acute cardiac insufficiency, oxygen utilizes the comprehensive function of Chinese medicine by the effective measures of resorb behind the ethanol, can treat rheumatism effectively, simultaneously can carry out comprehensively regulating to liver, spleen, lung, kidney, stomach, intestinal etc. again, and without any side effects.
Oral medicinal liquor of the present invention without any high-temperature process, has guaranteed original composition of various Chinese medicine cells, has strengthened the positive effect of Drug therapy, and dosing little (each 5-10ml), takes simple (every day sooner or later on an empty stomach respectively once), and the winter, Xia Junke took.
Medicinal preparation for oral administration of the present invention is evident in efficacy, and each patient has all stopped any Western medicine when taking oral medicinal liquor, the taking of Chinese medicine, and stopped the instillation of liquid.After beginning to take medicine, sb.'s illness took a favorable turn, and without any side effects, and condition of illness is no longer recurrence also.Taking the mid-term course of treatment, effect is more obvious; After the course of treatment, refuse to obey any medicine more than half a year, disease can not recur, and serve on several courses of treatment, can cure the disease and effect a permanent cure, and reaches the purpose of rehabilitation.And solved other medicine fully to the existing dependency of cardiovascular and cerebrovascular diseases, and rebound phenomena, effective percentage reaches 100%, and the rehabilitation rate reaches 90%.
The present invention mainly approach of curing the disease is: expelling pathogenic wind from the body surface → remove evil pain relieving → promoting blood circulation to restore menstrual flow network → blood vessel dilating → conditioning blood pressure → cholesterol reducing → reinforcing the heart nourish heart → nurse one's health blood source → coordinating YIN and YANG → each organ of conditioning health → attack skin ulcer toxin expelling → raising immunity normally moves the dirty meridians of each device of human body.Under the effect of medicated wine, make the oxygen and the efficacy of a drug arrive each position of health rapidly.
Beneficial effect of the present invention:
Clinical case is selected, is diagnosed and cures
The clinical experiment case has been selected through ground district hospital, and after County Hospital and the clinic's treatment and after taking other Chinese patent medicine and Western medicine, the state of an illness constantly rebounds, and also has the 50 routine patients that life is lost the confidence fully to take this oral medicinal liquor, is experimental group.Selecting 20 routine similar patients to take other medicines or treat by transfusion is matched group.
Patient's incidence is: cardiopalmus, impatient, have palpitation, breathe hard, suffer a shock, difficultly round the clock sleep, feel dizzy, numb limbs and tense tendons, general weakness, pale complexion, nauseating, blurred vision, fidgety, weak; Case history is diagnosed as: diseases such as blood supply insufficiency, hypertension, hyperlipidemia, cerebral thrombosis, coronary heart disease.
Experimental group and matched group are as shown in the table
Figure C20041001211900071
Model case: Xue so-and-so, the woman, 50 years old, the peasant, is mixed with shortened tongue, the askew phenomenon of mouth at coronary heart disease, hyperlipidemia, cerebral blood supply insufficiency, cerebral thrombosis cardiopalmus, headache, tinnitus, caligation, can not sleep, can not work, condition of illness such as pale complexion, it is invalid to cure everywhere, begin to take oral medicinal liquor of the present invention, half course of treatment in July, 99 after, condition of illness disappears, after the course of treatment, physical rehabilitation has arrived ordinary person's state, serve on two courses of treatment, consolidated, in the past few years, managing onerous toil, morbidity again has not been full of hope to life.
Wu so-and-so, the man, 60 years old, coronary heart disease, pericarditis, headache, weak, have palpitation, give vent to anger very difficult, irritated, can not ortho sleep, begin to take oral medicinal liquor of the present invention after half course of treatment, nervous phenomenon disappears, breathe transfer normal, course of treatment to after the state of an illness continue to take a turn for the better, serve on two courses of treatment, condition of illness disappears, broken away from forever take oral liquid before, the dependence phenomenon that relies on transfusion to keep.
By above two examples being taken the clinical observation of oral medicinal liquor case of the present invention and they having been carried out comprehensive investigation and return visit, the consistent cardio cerebrovascular affection that confirmed has all obtained effective treatment after taking this agent, and the rehabilitation rate can reach more than 90%, and the bounce-back rate is extremely low.
The specific embodiment
Take by weighing following component, every part is calculated with 10 grams,
13 parts of 13 parts of Radix Dipsacis of 13 portions of Radix Paeoniae Albas of 13 parts of Radix Rehmanniaes Preparata of Radix Angelicae Sinensis
13 parts of 13 portions of Caulis Spatholobis of 13 portions of Fructus Chaenomeliss of 13 parts of Radix Clematidis of Fructus Psoraleae
13 parts of 13 parts of Herba Siegesbeckiae of 13 portions of Radix Rubiaes of 13 parts of Radix Saposhnikoviaes of Radix Achyranthis Bidentatae
13 parts of 13 parts of Fructus Arctiis of 13 parts of Rhizoma Chuanxiongs of 13 parts of Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.)s of Radix Salviae Miltiorrhizae
10 parts of 10 parts of Actinolitum of 10 parts of Herba Epimedii of 10 parts of Radix Angelicae Pubescentiss of Rhizoma Drynariae
15 parts of 15 parts of Radix Puerariaes of 15 parts of Cortexs Eucommiae of 13 portions of Rhizoma Dioscoreaes of Cortex Acanthopancis
3 parts of 6 parts of Squama Maniss of 6 portions of Ganoderma lucidum seu Japonicumes of 15 parts of Flos Carthamis of the Radix Polygoni Multiflori
1.5 parts of 1.5 portions of Radix Aconiti Kusnezoffii of 3 parts of Herba Asaris of 3 portions of Scorpios of Flos Caryophylli;
Surplus is that alcoholic strength is 38% oleo stock Chinese liquor.
Above-mentioned each component is adopted following method preparation:
A, take by weighing each dry Chinese medicine mixing, be ground into 100 orders in its ratio;
B, soak 80g medicated powder by the 500ml wine liquid and take by weighing (alcoholic strength is about 38%); Soaking 400g medicated powder with the 2500ml wine liquid is a course of treatment.
C, immersion are poured medicated powder in jar or the glass container into, slowly add Chinese liquor, and stir with Glass rod or wooden stick, and fully fusion seals, and is stirred in the immersion;
D, extraction were soaked after 60 days, fully stirred again, after the clarification, poured out supernatant, again with medicinal residues with pressing bean curd method elimination medicinal liquid, mixes with supernatant, disgorging pours into supernatant in the disinfectant bottle, seals, packs and get final product with aseptic manipulation.

Claims (2)

1, a kind of oral medicinal liquor for the treatment of cardiovascular and cerebrovascular disease is that the preparation of raw material by following weight ratio forms,
Radix Angelicae Sinensis 6-13 part Radix Rehmanniae Preparata 6-13 part Radix Paeoniae Alba 6-13 part Radix Dipsaci 6-13 part
Fructus Psoraleae 6-13 part Radix Clematidis 6-13 part Fructus Chaenomelis 6-13 part Caulis Spatholobi 6-13 part
Radix Achyranthis Bidentatae 6-13 part Radix Saposhnikoviae 6-13 part Radix Rubiae 6-13 part Herba Siegesbeckiae 6-13 part
Radix Salviae Miltiorrhizae 3-13 part Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 6-13 part Rhizoma Chuanxiong 3-13 part Fructus Arctii 6-13 part
Rhizoma Drynariae 3-10 part Radix Angelicae Pubescentis 3-10 part Herba Epimedii 3-10 part Actinolitum 3-10 part
Cortex Acanthopancis 6-13 part Rhizoma Dioscoreae 6-15 part Cortex Eucommiae 6-15 part Radix Puerariae 6-15 part
Radix Polygoni Multiflori 10-15 part Flos Carthami 3-6 part Ganoderma lucidum seu Japonicum 6-10 part Squama Manis 3-10 part
Flos Caryophylli 1-3 part Scorpio 3-10 part Herba Asari 2-3 part Radix Aconiti Kusnezoffii 1.5-3 part;
Surplus is that alcoholic strength is the oleo stock Chinese liquor of 30-60%.
2, a kind of oral medicinal liquor for the treatment of cardiovascular and cerebrovascular disease is that the preparation of raw material by following weight ratio forms,
13 parts of 13 parts of Radix Dipsacis of 13 portions of Radix Paeoniae Albas of 13 parts of Radix Rehmanniaes Preparata of Radix Angelicae Sinensis
13 parts of 13 portions of Caulis Spatholobis of 13 portions of Fructus Chaenomeliss of 13 parts of Radix Clematidis of Fructus Psoraleae
13 parts of 13 parts of Herba Siegesbeckiae of 13 portions of Radix Rubiaes of 13 parts of Radix Saposhnikoviaes of Radix Achyranthis Bidentatae
13 parts of 13 parts of Fructus Arctiis of 13 parts of Rhizoma Chuanxiongs of 13 parts of Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.)s of Radix Salviae Miltiorrhizae
10 parts of 10 parts of Actinolitum of 10 parts of Herba Epimedii of 10 parts of Radix Angelicae Pubescentiss of Rhizoma Drynariae
15 parts of 15 parts of Radix Puerariaes of 15 parts of Cortexs Eucommiae of 13 portions of Rhizoma Dioscoreaes of Cortex Acanthopancis
3 parts of 6 parts of Squama Maniss of 6 portions of Ganoderma lucidum seu Japonicumes of 15 parts of Flos Carthamis of the Radix Polygoni Multiflori
1.5 parts of 1.5 portions of Radix Aconiti Kusnezoffii of 3 parts of Herba Asaris of 3 portions of Scorpios of Flos Caryophylli;
Surplus is that alcoholic strength is 38% oleo stock Chinese liquor.
CNB2004100121197A 2004-01-14 2004-01-14 Oral administered medicated wine for treating cardiovascular and cerebrovascular diseases Expired - Fee Related CN1241602C (en)

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CN1241602C true CN1241602C (en) 2006-02-15

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