CN1569366A - Nano-silver aqueous solution preparation and its preparation method, use and using method - Google Patents
Nano-silver aqueous solution preparation and its preparation method, use and using method Download PDFInfo
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- CN1569366A CN1569366A CN 200410022463 CN200410022463A CN1569366A CN 1569366 A CN1569366 A CN 1569366A CN 200410022463 CN200410022463 CN 200410022463 CN 200410022463 A CN200410022463 A CN 200410022463A CN 1569366 A CN1569366 A CN 1569366A
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Abstract
The invention relates to a nanometer silver aqueous solution preparation. Its components and weight percentage are: nanometer silver 0.05-1.5, the dispersant 0.5-1.5, the reducer 0.05-0.2, the stabilizer is nanometer silver 0.5-1.5, the dispersant 0.5-1.5, the reducer is 0.05-0.2, the stabilizer is 0.5-10, and the deioned water is 1000. The invention also relates the manufacturing method for above mentioned nanometer silver aqueous solution preparation, and the usage for curing man social disease, and the using method for ejecting the medicine into bladder through urethra. The reducer and stabilizer in the solution accord with the standards of America FDA or china sanitary department.
Description
(1) technical field:
The present invention relates to a kind of Nano Silver preparation, particularly a kind of nano-silver water solution preparation with anti-inflammatory, antibacterial action; The invention still further relates to preparation method, purposes and the using method of above-mentioned nano-silver water solution preparation.
(2) background technology:
Modern medicine confirms, Nano Silver has outstanding antibacterial ability, has a broad antifungal spectrum, to the Glanz positive bacteria, the Glanz negative bacterium, fungi, anaerobic bacteria all has tangible antibacterial functions, especially to the same tool sterilizing ability of drug resistance pathogenic bacteria, as staphylococcus aureus, Escherichia coli, gonococcus, candida albicans, Pseudomonas aeruginosa, micrococcus scarlatinae, bacillus subtilis, pneumobacillus, pathogenic bacteria such as anaerobic bacteria, also can kill chlamydia trachomatis, and avirulence, no anaphylaxis, nonirritant, therefore be made into pulvis, anti-inflammatory film and gel are used clinically, as application number is 01110767.7, name is called " aggregation-preventing nanometer wide-spectrum antibacterial silve powder and inductrial production process ", application number is 01129505.8, name is called " Nano Silver gynaecological disease antimicrobial inflammation-relieving film and industrialized producing technology thereof " and application number is 01129507.4, name is called " nanometer silver antimicrobial inflammation-relieving gel for curing prostatitis and industrialized producing technology thereof ", these pulvis, antibacterial film and gel can be used for the treatment of vaginitis, male prostatitis and senile organic prostatitis, its using method is by vagina or the direct administration of rectum, because pulvis, anti-inflammatory film and gel all can't inject urethra and bladder, therefore still unmanned Nano Silver preparation for treating male venereal disease and urethra and the bladder disease used.
(3) summary of the invention:
The present invention will disclose a kind of nano-silver water solution preparation that can inject urethra and bladder.The present invention also will disclose preparation method, purposes and the using method of above-mentioned nano-silver water solution preparation.
The composition and the weight fraction of nano-silver water solution preparation of the present invention are as follows:
Nano Silver 0.05～1.5, dispersant 0.5～1.5, reducing agent 0.05～0.2, stabilizing agent are 0.5～10, deionized water 1000.
The preferred weight of above-mentioned each composition of aqueous solution preparation is divided into:
Nano Silver 0.08～1.2, dispersant 0.8～1.2, reducing agent 0.1～0.15, stabilizing agent are 0.8～2, deionized water 1000.
The optimum weight of above-mentioned each composition of nano-silver water solution preparation is divided into:
Nano Silver 0.35, dispersant 1, reducing agent 0.12, stabilizing agent are 1, deionized water 1000.
Reducing agent generally uses sulphite described in the above-mentioned nano-silver water solution preparation, preferably uses Sodium Metabisulfite or sodium sulfite; Described stabilizing agent preferably uses V
E,, V
COr different V
CIn a kind of, or between them with any proportional quantity, the mixture that is arbitrarily made with; Described dispersant generally uses the high molecular polymer class, and surfactant-based and organic acid dispersant preferably uses triethanolamine.
Nano-silver water solution preparation of the present invention can be made according to a conventional method, but its preparation method is best:
1) takes by weighing raw material in proportion;
2) with ultrasonic wave nano-silver powder is made dispersion treatment;
3) add deionized water and make dilution;
4) in dilution, add reducing agent and stabilizing agent and dispersant;
5) can, sealing are preserved.
Wherein said reducing agent generally uses sulphite, preferably uses Sodium Metabisulfite or sodium sulfite; Described stabilizing agent preferably uses V
E,, V
COr different V
CIn a kind of, or between them with any proportional quantity, the mixture that is arbitrarily made with; Described dispersant generally uses the high molecular polymer class, and surfactant-based and organic acid dispersant preferably uses triethanolamine.
Nano-silver water solution preparation of the present invention is particularly suitable for treating urethra, bladder disease and male venereal disease.
The using method of nano-silver water solution preparation of the present invention when being used for the treatment of urethra, bladder disease and male venereal disease is to inject bladder by urethra.
Because the present invention is a kind of aqueous solution preparation, therefore easily inject urethra and bladder, can be used for treating urethra and bladder inflammation, particularly treat male venereal disease.What the present invention was the most outstanding is also advantageous in that, all reducing agents in the nano-silver water solution preparation of the present invention and stabilizing agent all are through U.S. FDA or ministry of Health of China approval, can be applied to the additive in food or the medicine, and use amount is limited the quantity of less than maximum, therefore human body is not had spread effect, long-term use can not cause bad reactions such as poisoning.Safety testing shows this product avirulence, no anaphylaxis, to skin, mucous membrane nonirritant, and no sensitization, rapid-action, good effect has no side effect.Employed assistant agent or additive all can be buied from market among the present invention, also can adopt the conventional similar product that uses in the industry, therefore are convenient to large-scale industrialization production.
(4) specific embodiment:
Below further specify the present invention by specific embodiment, but embodiment only be used for the explanation, can not limit the scope of the invention.
Embodiment one
1) ratio takes by weighing Nano Silver 0.35 gram, triethanolamine 1 gram, Sodium Metabisulfite 0.12 gram, V
E1 gram, deionized water 1000 grams;
2) nano-silver powder is made dispersion treatment with ultrasonic wave;
3) add deionized water and make dilution;
4) in dilution, add Sodium Metabisulfite, triethanolamine and V
E
5) stir, can, sealing are preserved.
The said goods is to killing effect such as the following table of various germs:
As seen from the above table, product of the present invention can be killed multiple venereal disease germ in 8～12 hours, be a kind of medicine of good treatment venereal disease.
It is as follows that the said goods is used for the male venereal disease result of treatment:
Treat clinical std patient 38 examples, be the male sex, age between 25～53, wherein infection of staphylococcus aureus person 3 examples, charrin's disease person 5 examples, candida albicans infection person 4 examples, gonococcal infection person 7 examples, mycoplasma infection person 9 examples, choamydiae infection person 5 examples, trichomonas vaginalis infection person 5 examples.
Methods of treatment is to adopt the mode of this product being injected bladder from urethra.Inject a deuterzooid product every day, inject 40ml at every turn, treating six days is a course of treatment, treats two courses of treatment continuously, and cure rate is 95%.The cooperation antibiotic therapy of in particular cases can following the doctor's advice.
Embodiment two
1) takes by weighing Nano Silver 0.15 gram, triethanolamine 1 gram, sodium sulfite 0.05 gram, V
E, V
CWith different V
CEach 0.5 gram, deionized water 1000 grams;
2) nano-silver powder is made dispersion treatment with ultrasonic wave;
3) add deionized water and make dilution;
4) in dilution, add sodium sulfite, triethanolamine, V
E, and different V
C
5) stir, can, sealing are preserved.
Claims (10)
1, a kind of nano-silver water solution preparation, the weight distribution ratio of its each composition is as follows:
Nano Silver 0.05～1.5, dispersant 0.5～1.5, reducing agent 0.05～0.2, stabilizing agent are 0.5～10, deionized water 1000.
2, nano-silver water solution preparation according to claim 1 is characterized in that wherein the weight distribution ratio of each composition is as follows:
Nano Silver 0.08～1.2, dispersant 0.8～1.2, reducing agent 0.1～0.15, stabilizing agent 0.8～2, deionized water 1000.
3, nano-silver water solution preparation according to claim 2 is characterized in that wherein the weight distribution ratio of each composition is as follows:
Nano Silver 0.35, dispersant 1, reducing agent 0.12, stabilizing agent are 1, deionized water 1000.
4, according to the described nano-silver water solution preparation of claim 1～3, it is characterized in that: wherein said reducing agent is a sulphite.
5, nano-silver water solution preparation according to claim 4 is characterized in that: described reducing agent is Sodium Metabisulfite or sodium sulfite.
6, according to the described nano-silver water solution preparation of claim 1～3, it is characterized in that: described stabilizing agent is a kind of among VE, VC or the different VC, or between them with any proportional quantity, the mixture formed of compound mode arbitrarily.
7, according to the described nano-silver water solution preparation of claim 1～3, it is characterized in that: dispersant is the high molecular polymer class, and surfactant-based and organic acid dispersant is preferably triethanolamine.
8, the preparation method of nano-silver water solution preparation:
1) takes by weighing raw material in proportion;
2) nano-silver powder is made dispersion treatment with ultrasonic wave;
3) add deionized water and make dilution;
4) in dilution, add reducing agent, dispersant and stabilizing agent;
5) can, sealing are preserved.
9, the nano-silver water solution preparation is in the purposes of preparation treatment urethra, bladder disease and male venereal disease medicine.
10, the using method of nano-silver water solution preparation is to inject bladder by urethra.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410022463 CN1245152C (en) | 2004-04-30 | 2004-04-30 | Nano-silver aqueous solution preparation and its preparation method, use and using method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410022463 CN1245152C (en) | 2004-04-30 | 2004-04-30 | Nano-silver aqueous solution preparation and its preparation method, use and using method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1569366A true CN1569366A (en) | 2005-01-26 |
| CN1245152C CN1245152C (en) | 2006-03-15 |
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| CN 200410022463 Expired - Fee Related CN1245152C (en) | 2004-04-30 | 2004-04-30 | Nano-silver aqueous solution preparation and its preparation method, use and using method |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007014497A1 (en) * | 2005-08-04 | 2007-02-08 | Chenlung Lin | A composition comprising silver nanoparticles and the use thereof |
| CN100425375C (en) * | 2006-04-03 | 2008-10-15 | 庄平 | Nano-class silver colloidal solution and preparation method thereof |
| CN102510783A (en) * | 2010-08-27 | 2012-06-20 | 同和电子科技有限公司 | Low-temperature sinterable silver nanoparticle composition and electronic component formed using that composition |
| CN103817348A (en) * | 2014-03-21 | 2014-05-28 | 德华兔宝宝装饰新材股份有限公司 | Nano-silver aqueous solution and application method for applying nano-silver aqueous solution to technical wood |
| CN103817753A (en) * | 2014-03-21 | 2014-05-28 | 德华兔宝宝装饰新材股份有限公司 | Anti-mould and antibacterial nano-silver floor |
| CN103817754A (en) * | 2014-03-21 | 2014-05-28 | 德华兔宝宝装饰新材股份有限公司 | Nano-silver floor |
| CN103832205A (en) * | 2014-03-21 | 2014-06-04 | 德华兔宝宝装饰新材股份有限公司 | Nano silver decoration laminated board |
| CN103862988A (en) * | 2014-03-21 | 2014-06-18 | 德华兔宝宝装饰新材股份有限公司 | Mildew-resistant and antibacterial nano-silver decorative laminated board |
| CN104473965A (en) * | 2005-08-04 | 2015-04-01 | 林成龙 | Composition containing silver nanoparticles and application thereof |
| CN105640986A (en) * | 2014-11-28 | 2016-06-08 | 广东工业大学 | Silver nanoparticle composition for control of lung cancer and prostate cancer |
-
2004
- 2004-04-30 CN CN 200410022463 patent/CN1245152C/en not_active Expired - Fee Related
Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007014497A1 (en) * | 2005-08-04 | 2007-02-08 | Chenlung Lin | A composition comprising silver nanoparticles and the use thereof |
| CN104473965A (en) * | 2005-08-04 | 2015-04-01 | 林成龙 | Composition containing silver nanoparticles and application thereof |
| CN101287477B (en) * | 2005-08-04 | 2014-10-08 | 林成龙 | A composition comprising silver nanoparticles and its use |
| CN100425375C (en) * | 2006-04-03 | 2008-10-15 | 庄平 | Nano-class silver colloidal solution and preparation method thereof |
| CN102510783A (en) * | 2010-08-27 | 2012-06-20 | 同和电子科技有限公司 | Low-temperature sinterable silver nanoparticle composition and electronic component formed using that composition |
| US8673049B2 (en) | 2010-08-27 | 2014-03-18 | Dowa Electronics Materials Co., Ltd. | Low-temperature sintered silver nanoparticle composition and electronic articles formed using the same |
| CN102510783B (en) * | 2010-08-27 | 2015-07-22 | 同和电子科技有限公司 | Low-temperature sinterable silver nanoparticle composition and electronic component formed using that composition |
| CN103862988A (en) * | 2014-03-21 | 2014-06-18 | 德华兔宝宝装饰新材股份有限公司 | Mildew-resistant and antibacterial nano-silver decorative laminated board |
| CN103832205A (en) * | 2014-03-21 | 2014-06-04 | 德华兔宝宝装饰新材股份有限公司 | Nano silver decoration laminated board |
| CN103817754A (en) * | 2014-03-21 | 2014-05-28 | 德华兔宝宝装饰新材股份有限公司 | Nano-silver floor |
| CN103817753A (en) * | 2014-03-21 | 2014-05-28 | 德华兔宝宝装饰新材股份有限公司 | Anti-mould and antibacterial nano-silver floor |
| CN103817348A (en) * | 2014-03-21 | 2014-05-28 | 德华兔宝宝装饰新材股份有限公司 | Nano-silver aqueous solution and application method for applying nano-silver aqueous solution to technical wood |
| CN103817754B (en) * | 2014-03-21 | 2015-09-16 | 德华兔宝宝装饰新材股份有限公司 | A kind of Nano Silver floor |
| CN103817753B (en) * | 2014-03-21 | 2015-11-25 | 德华兔宝宝装饰新材股份有限公司 | A kind of Nano Silver floor of antimildew and antibacterial |
| CN103817348B (en) * | 2014-03-21 | 2015-12-02 | 德华兔宝宝装饰新材股份有限公司 | A kind of nano-silver water solution and the using method for Recombinant Wood thereof |
| CN103862988B (en) * | 2014-03-21 | 2016-02-03 | 德华兔宝宝装饰新材股份有限公司 | A kind of Nano Silver decoration veneer of antimildew and antibacterial |
| CN105640986A (en) * | 2014-11-28 | 2016-06-08 | 广东工业大学 | Silver nanoparticle composition for control of lung cancer and prostate cancer |
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