CN1443187A - 有核激素受体功能的稠环调节剂 - Google Patents

有核激素受体功能的稠环调节剂 Download PDF

Info

Publication number: CN1443187A
Authority: CN; China
Prior art keywords: replacement; imidazo; alkyl; methylene radical; aryl
Prior art date: 2000-06-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

CN01811976A

Other languages

English (en)

Chinese (zh)

Inventor

M·E·萨尔瓦蒂

J·A·巴洛

单伟芳

S·吉斯

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Squibb Co

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-28

Filing date

2001-06-20

Publication date

2003-09-17

2001-06-20 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2003-09-17 Publication of CN1443187A publication Critical patent/CN1443187A/zh

Status Pending legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

CN01811976A 2000-06-28 2001-06-20 有核激素受体功能的稠环调节剂 Pending CN1443187A (zh)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date
US21439200P	2000-06-28	2000-06-28
US60/214,392		2000-06-28
US28443801P	2001-04-18	2001-04-18
US28461701P	2001-04-18	2001-04-18
US60/284,438		2001-04-18
US60/284,617		2001-04-18

Publications (1)

Publication Number	Publication Date
CN1443187A true CN1443187A (zh)	2003-09-17

Family

ID=27395986

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CN01811976A Pending CN1443187A (zh)	2000-06-28	2001-06-20	有核激素受体功能的稠环调节剂

Country Status (9)

Country	Link
KR (1)	KR20030014407A (es)
CN (1)	CN1443187A (es)
AR (1)	AR031709A1 (es)
CZ (1)	CZ20024250A3 (es)
IL (1)	IL152890A0 (es)
PE (1)	PE20030186A1 (es)
PL (1)	PL366565A1 (es)
TR (1)	TR200202702T2 (es)
UY (1)	UY26809A1 (es)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102702013A (zh) *	2005-11-28	2012-10-03	Gtx公司	核受体结合剂
CN102875556A (zh) *	2011-07-12	2013-01-16	上海药明康德新药开发有限公司	(4s)-1-取代-2,5-二氮杂双环[2,2,1]庚烷衍生物及制备方法
US9051267B2 (en)	2005-11-28	2015-06-09	Gtx, Inc.	Estrogen receptor ligands and methods of use thereof
US9409856B2 (en)	2005-11-28	2016-08-09	Gtx, Inc.	Estrogen receptor ligands and methods of use thereof
CN110577995A (zh) *	2019-07-11	2019-12-17	德阳市人民医院	男性骨质疏松症的诊断标志物

2001
- 2001-06-20 KR KR1020027017857A patent/KR20030014407A/ko not_active Withdrawn
- 2001-06-20 TR TR2002/02702T patent/TR200202702T2/ unknown
- 2001-06-20 CN CN01811976A patent/CN1443187A/zh active Pending
- 2001-06-20 CZ CZ20024250A patent/CZ20024250A3/cs unknown
- 2001-06-20 PL PL01366565A patent/PL366565A1/xx not_active Application Discontinuation
- 2001-06-20 IL IL15289001A patent/IL152890A0/xx unknown
- 2001-06-28 AR ARP010103100A patent/AR031709A1/es unknown
- 2001-06-28 UY UY26809A patent/UY26809A1/es not_active Application Discontinuation
- 2001-08-23 PE PE2001000651A patent/PE20030186A1/es not_active Application Discontinuation

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102702013A (zh) *	2005-11-28	2012-10-03	Gtx公司	核受体结合剂
US9051267B2 (en)	2005-11-28	2015-06-09	Gtx, Inc.	Estrogen receptor ligands and methods of use thereof
CN102702013B (zh) *	2005-11-28	2016-02-10	Gtx公司	核受体结合剂
US9409856B2 (en)	2005-11-28	2016-08-09	Gtx, Inc.	Estrogen receptor ligands and methods of use thereof
CN102875556A (zh) *	2011-07-12	2013-01-16	上海药明康德新药开发有限公司	(4s)-1-取代-2,5-二氮杂双环[2,2,1]庚烷衍生物及制备方法
CN110577995A (zh) *	2019-07-11	2019-12-17	德阳市人民医院	男性骨质疏松症的诊断标志物
CN110577995B (zh) *	2019-07-11	2020-11-06	德阳市人民医院	男性骨质疏松症的诊断标志物

Also Published As

Publication number	Publication date
PL366565A1 (en)	2005-02-07
TR200202702T2 (tr)	2004-12-21
CZ20024250A3 (cs)	2003-10-15
KR20030014407A (ko)	2003-02-17
IL152890A0 (en)	2003-06-24
UY26809A1 (es)	2002-01-31
PE20030186A1 (es)	2003-03-23
AR031709A1 (es)	2003-10-01

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Legal Events

Date	Code	Title
2003-09-17	C06	Publication
2003-09-17	PB01	Publication
2003-12-03	C10	Entry into substantive examination
2003-12-03	SE01	Entry into force of request for substantive examination
2006-10-04	C02	Deemed withdrawal of patent application after publication (patent law 2001)
2006-10-04	WD01	Invention patent application deemed withdrawn after publication