CN1304363C - N－甲基－高半胱氨酸及其应用以及制备方法 - Google Patents

N－甲基－高半胱氨酸及其应用以及制备方法 Download PDF

Info

Publication number: CN1304363C
Authority: CN; China
Prior art keywords: methyl; compound; formula; oxygen base; acid
Prior art date: 2001-11-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CNB028228235A

Other languages

English (en)

Chinese (zh)

Other versions

CN1589257A (zh

Inventor

马克·维卢恩

约翰内斯·普拉策克

埃克哈德·奥托

奥尔林·彼得罗夫

克劳迪娅·博尔姆

迪尔克·欣茨

格雷戈尔·曼

约翰·利斯特-詹姆斯

戴维·M·威尔逊

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

CIS Bio International SA

Original Assignee

CIS Bio International SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-15

Filing date

2002-10-22

Publication date

2007-03-14

2002-10-22 Application filed by CIS Bio International SA filed Critical CIS Bio International SA

2005-03-02 Publication of CN1589257A publication Critical patent/CN1589257A/zh

2007-03-14 Application granted granted Critical

2007-03-14 Publication of CN1304363C publication Critical patent/CN1304363C/zh

2022-10-22 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/52—Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Biophysics (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical Kinetics & Catalysis (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

CNB028228235A 2001-11-15 2002-10-22 N－甲基－高半胱氨酸及其应用以及制备方法 Expired - Fee Related CN1304363C (zh)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US33141601P	2001-11-15	2001-11-15
US60/331,416		2001-11-15
DE10215336A DE10215336A1 (de)	2002-03-28	2002-03-28	N-Methyl-Homocysteine und ihre Verwendung sowie Verfahren zu ihrer Herstellung
DE10215336.1		2002-03-28

Publications (2)

Publication Number	Publication Date
CN1589257A CN1589257A (zh)	2005-03-02
CN1304363C true CN1304363C (zh)	2007-03-14

Family

ID=28458629

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CNB028228235A Expired - Fee Related CN1304363C (zh)	2001-11-15	2002-10-22	N－甲基－高半胱氨酸及其应用以及制备方法

Country Status (17)

Country	Link
US (1)	US7659364B2 (no)
EP (1)	EP1444194B1 (no)
JP (1)	JP4264353B2 (no)
KR (1)	KR20050039739A (no)
CN (1)	CN1304363C (no)
AT (1)	ATE451347T1 (no)
AU (1)	AU2002348998B9 (no)
BR (1)	BR0214103A (no)
CA (1)	CA2467264A1 (no)
DE (2)	DE10215336A1 (no)
IL (1)	IL161974A0 (no)
MX (1)	MXPA04004526A (no)
NO (1)	NO20042469L (no)
PL (1)	PL369244A1 (no)
RU (1)	RU2305678C2 (no)
WO (1)	WO2003042163A1 (no)
ZA (1)	ZA200404713B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN103373940B (zh) *	2012-04-26	2015-07-15	长春百克生物科技股份公司	一种针对非活泼侧链的n-fmoc-氨基酸粗品结晶的新工艺
CN103901211B (zh) *	2014-03-13	2015-07-29	复旦大学	一种dl-高半胱氨酸可视识别的新方法
KR20220133572A (ko)	2021-03-25	2022-10-05	박종윤	건강기록부
CN113004392A (zh) *	2021-03-26	2021-06-22	清华大学深圳国际研究生院	S-腺苷同型半胱氨酸人工完全抗原及其制备方法、应用
US20240002491A1 (en)	2022-04-27	2024-01-04	Regeneron Pharmaceuticals, Inc.	Methods for selecting patients for treatment with an ngf antagonist

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5932189A (en) *	1994-07-29	1999-08-03	Diatech, Inc.	Cyclic peptide somatostatin analogs
US6358491B1 (en) *	1999-08-27	2002-03-19	Berlex Laboratories, Inc.	Somatostatin analogs
CA2390658A1 (en) *	1999-11-19	2001-05-25	Scott J. Hultgren	Pyridinones to treat and prevent bacterial infections
US6841559B1 (en) *	1999-11-19	2005-01-11	Washington University Of St. Louis	Pyridinones to treat and prevent bacterial infections
US6333410B1 (en) *	2000-08-18	2001-12-25	Immunogen, Inc.	Process for the preparation and purification of thiol-containing maytansinoids
TW526395B (en) *	2000-09-29	2003-04-01	United Microelectronics Corp	Method to improve side profile of photoresist pattern

2002
- 2002-03-28 DE DE10215336A patent/DE10215336A1/de not_active Withdrawn
- 2002-10-22 DE DE50214080T patent/DE50214080D1/de not_active Expired - Lifetime
- 2002-10-22 BR BR0214103-5A patent/BR0214103A/pt not_active IP Right Cessation
- 2002-10-22 AU AU2002348998A patent/AU2002348998B9/en not_active Ceased
- 2002-10-22 JP JP2003544000A patent/JP4264353B2/ja not_active Expired - Fee Related
- 2002-10-22 AT AT02781275T patent/ATE451347T1/de not_active IP Right Cessation
- 2002-10-22 EP EP02781275A patent/EP1444194B1/de not_active Expired - Lifetime
- 2002-10-22 CN CNB028228235A patent/CN1304363C/zh not_active Expired - Fee Related
- 2002-10-22 WO PCT/EP2002/011779 patent/WO2003042163A1/de not_active Ceased
- 2002-10-22 CA CA002467264A patent/CA2467264A1/en not_active Abandoned
- 2002-10-22 RU RU2004118248/04A patent/RU2305678C2/ru not_active IP Right Cessation
- 2002-10-22 IL IL16197402A patent/IL161974A0/xx unknown
- 2002-10-22 MX MXPA04004526A patent/MXPA04004526A/es active IP Right Grant
- 2002-10-22 PL PL02369244A patent/PL369244A1/xx not_active Application Discontinuation
- 2002-10-22 KR KR1020047007070A patent/KR20050039739A/ko not_active Ceased
- 2002-11-15 US US10/295,043 patent/US7659364B2/en not_active Expired - Fee Related
2004
- 2004-06-14 ZA ZA200404713A patent/ZA200404713B/en unknown
- 2004-06-14 NO NO20042469A patent/NO20042469L/no unknown

Also Published As

Publication number	Publication date
HK1074833A1 (en)	2005-11-25
IL161974A0 (en)	2005-11-20
CN1589257A (zh)	2005-03-02
NO20042469L (no)	2004-06-14
PL369244A1 (en)	2005-04-18
MXPA04004526A (es)	2004-08-11
CA2467264A1 (en)	2003-05-22
DE10215336A1 (de)	2003-10-23
RU2004118248A (ru)	2006-01-10
AU2002348998B2 (en)	2009-01-29
EP1444194B1 (de)	2009-12-09
WO2003042163A1 (de)	2003-05-22
AU2002348998B9 (en)	2009-03-12
BR0214103A (pt)	2004-09-28
US20030120032A1 (en)	2003-06-26
JP2005509023A (ja)	2005-04-07
DE50214080D1 (de)	2010-01-21
US7659364B2 (en)	2010-02-09
ATE451347T1 (de)	2009-12-15
KR20050039739A (ko)	2005-04-29
EP1444194A1 (de)	2004-08-11
RU2305678C2 (ru)	2007-09-10
ZA200404713B (en)	2005-06-14
JP4264353B2 (ja)	2009-05-13

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Legal Events

Date	Code	Title	Description
2005-03-02	C06	Publication
2005-03-02	PB01	Publication
2005-05-04	C10	Entry into substantive examination
2005-05-04	SE01	Entry into force of request for substantive examination
2005-11-25	REG	Reference to a national code	Ref country code: HK Ref legal event code: DE Ref document number: 1074833 Country of ref document: HK
2006-08-23	ASS	Succession or assignment of patent right	Owner name: CIS BIOLOGY INTERNATIONAL CO., LTD. Free format text: FORMER OWNER: SCHERING AG Effective date: 20060721
2006-08-23	C41	Transfer of patent application or patent right or utility model
2006-08-23	TA01	Transfer of patent application right	Effective date of registration: 20060721 Address after: French Thackeray Applicant after: CIS Biology International Co. Address before: Berlin Applicant before: Schering AG
2007-03-14	C14	Grant of patent or utility model
2007-03-14	GR01	Patent grant
2011-12-28	C17	Cessation of patent right
2011-12-28	CF01	Termination of patent right due to non-payment of annual fee	Granted publication date: 20070314 Termination date: 20101022