CN1207687A - 含有维生素d－类似物的药物制剂 - Google Patents
含有维生素d－类似物的药物制剂 Download PDFInfo
- Publication number
- CN1207687A CN1207687A CN96199734A CN96199734A CN1207687A CN 1207687 A CN1207687 A CN 1207687A CN 96199734 A CN96199734 A CN 96199734A CN 96199734 A CN96199734 A CN 96199734A CN 1207687 A CN1207687 A CN 1207687A
- Authority
- CN
- China
- Prior art keywords
- vitamin
- group
- hydrogen atom
- analogues
- pharmaceutical formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Nanotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19549243.9 | 1995-12-21 | ||
| DE19549243A DE19549243A1 (de) | 1995-12-21 | 1995-12-21 | Pharmazeutische Präparate enthaltend Clathrate von Cyclodextrinen und nichtnatürliche Vitamin D-Analoga |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1207687A true CN1207687A (zh) | 1999-02-10 |
Family
ID=7781710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96199734A Pending CN1207687A (zh) | 1995-12-21 | 1996-12-20 | 含有维生素d－类似物的药物制剂 |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0869819A1 (is) |
| JP (1) | JP2000502733A (is) |
| KR (1) | KR19990076637A (is) |
| CN (1) | CN1207687A (is) |
| AU (1) | AU1306997A (is) |
| CA (1) | CA2241205A1 (is) |
| DE (1) | DE19549243A1 (is) |
| HU (1) | HUP9903935A3 (is) |
| IL (1) | IL125020A0 (is) |
| IS (1) | IS4774A (is) |
| NO (1) | NO982874L (is) |
| WO (1) | WO1997023242A1 (is) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6538037B2 (en) | 1991-01-08 | 2003-03-25 | Bone Care International, Inc. | Methods for preparation and use of 1α,24(S)-dihydroxyvitamin D2 |
| US6503893B2 (en) | 1996-12-30 | 2003-01-07 | Bone Care International, Inc. | Method of treating hyperproliferative diseases using active vitamin D analogues |
| US6573256B2 (en) | 1996-12-30 | 2003-06-03 | Bone Care International, Inc. | Method of inhibiting angiogenesis using active vitamin D analogues |
| US6566353B2 (en) | 1996-12-30 | 2003-05-20 | Bone Care International, Inc. | Method of treating malignancy associated hypercalcemia using active vitamin D analogues |
| GB9826656D0 (en) | 1998-12-03 | 1999-01-27 | Novartis Ag | Organic compounds |
| US7094775B2 (en) | 2004-06-30 | 2006-08-22 | Bone Care International, Llc | Method of treating breast cancer using a combination of vitamin D analogues and other agents |
| DE102005017775A1 (de) * | 2005-04-13 | 2006-10-19 | Schering Ag | Komplexe aus Vitamin D-Verbindungen oder deren Analoga mit einem 5Z,7E,10(19)-Trien-System und methlierten Derivaten des ß-Cyclodextrins |
| PT3095447T (pt) | 2006-02-03 | 2022-01-24 | Opko Renal Llc | Tratamento da insuficiência e deficiência de vitamina d com 25-hidroxivitamina d2 e 25-hidroxivitamina d3 |
| SI2037936T1 (sl) | 2006-06-21 | 2014-11-28 | Opko Renal, Llc | Postopek zdravljenja in prepreäśevanja sekundarnega hiperparatiroidizma |
| KR100822133B1 (ko) * | 2006-11-06 | 2008-04-15 | 한미약품 주식회사 | 비타민 ｄ 또는 이의 유도체의 고체분산체 및비스포스포네이트를 포함하는, 골다공증 예방 또는 치료용복합제제 |
| EP3225243B1 (en) | 2007-04-25 | 2025-09-03 | Opko Renal, LLC | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
| JP5647516B2 (ja) | 2007-04-25 | 2014-12-24 | シトクロマ インコーポレイテッド | ビタミンｄ療法のための方法および化合物 |
| EP2148684B1 (en) | 2007-04-25 | 2013-01-16 | Cytochroma Inc. | Method of treating vitamin d insufficiency and deficiency |
| SI2481400T1 (sl) | 2007-04-25 | 2014-11-28 | Opko IP Holdings II, Inc. | Nadzorovano oralno sproščanje sestavkov, ki vsebujejo spojino vitamina D in voskasti nosilec |
| ES2593356T3 (es) | 2008-04-02 | 2016-12-07 | Opko Ireland Global Holdings, Ltd. | Métodos, composiciones, usos y kits útiles para la deficiencia de la vitamina D y trastornos relacionados |
| LT2552484T (lt) | 2010-03-29 | 2020-04-27 | Opko Ireland Global Holdings, Ltd. | Būdai ir kompozicijos, skirti paratiroidų lygiams sumažinti |
| KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 ｄ 방출 제형 |
| US10220047B2 (en) | 2014-08-07 | 2019-03-05 | Opko Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin D and articles therefor |
| MY198547A (en) | 2016-03-28 | 2023-09-04 | Opko Ireland Global Holdings Ltd | Methods of vitamin d treatment |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU177586B (en) * | 1978-12-19 | 1981-11-28 | Chinoin Gyogyszer Es Vegyeszet | New process for preparing stable inclusion complexes of vitamine d with cyclodextrin |
| JPS5910562A (ja) * | 1982-07-07 | 1984-01-20 | Teijin Ltd | プレ−１α−ヒドロキシコレカルシフエロ−ル類の製造法 |
| JPS5936656A (ja) * | 1982-08-23 | 1984-02-28 | Teijin Ltd | 新規包接化合物及びそれを活性成分とする薬剤 |
| JPS60120812A (ja) * | 1983-12-02 | 1985-06-28 | Teijin Ltd | 糖尿病性骨減少症治療剤 |
| DK0437225T3 (da) * | 1990-01-10 | 1994-06-27 | Hoffmann La Roche | Topiske præparater |
| IL107185A (en) * | 1992-10-06 | 1998-02-22 | Schering Ag | Vitamin d, 25-carboxylic acid derivatives and pharmaceutical compositions containing the same |
-
1995
- 1995-12-21 DE DE19549243A patent/DE19549243A1/de not_active Withdrawn
-
1996
- 1996-12-20 CA CA002241205A patent/CA2241205A1/en not_active Abandoned
- 1996-12-20 AU AU13069/97A patent/AU1306997A/en not_active Abandoned
- 1996-12-20 WO PCT/EP1996/005856 patent/WO1997023242A1/de not_active Ceased
- 1996-12-20 EP EP96944669A patent/EP0869819A1/de not_active Withdrawn
- 1996-12-20 IL IL12502096A patent/IL125020A0/xx unknown
- 1996-12-20 HU HU9903935A patent/HUP9903935A3/hu unknown
- 1996-12-20 JP JP9523335A patent/JP2000502733A/ja active Pending
- 1996-12-20 KR KR1019980704745A patent/KR19990076637A/ko not_active Withdrawn
- 1996-12-20 CN CN96199734A patent/CN1207687A/zh active Pending
-
1998
- 1998-06-15 IS IS4774A patent/IS4774A/is unknown
- 1998-06-19 NO NO982874A patent/NO982874L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL125020A0 (en) | 1999-01-26 |
| HUP9903935A3 (en) | 2000-05-29 |
| JP2000502733A (ja) | 2000-03-07 |
| NO982874D0 (no) | 1998-06-19 |
| CA2241205A1 (en) | 1997-07-03 |
| WO1997023242A1 (de) | 1997-07-03 |
| AU1306997A (en) | 1997-07-17 |
| NO982874L (no) | 1998-08-20 |
| IS4774A (is) | 1998-06-15 |
| DE19549243A1 (de) | 1997-06-26 |
| KR19990076637A (ko) | 1999-10-15 |
| HUP9903935A2 (hu) | 2000-03-28 |
| EP0869819A1 (de) | 1998-10-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| REG | Reference to a national code |
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