CN1201791C - Wind dispelling and pain relieving ointment - Google Patents
Wind dispelling and pain relieving ointment Download PDFInfo
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- CN1201791C CN1201791C CN 03105156 CN03105156A CN1201791C CN 1201791 C CN1201791 C CN 1201791C CN 03105156 CN03105156 CN 03105156 CN 03105156 A CN03105156 A CN 03105156A CN 1201791 C CN1201791 C CN 1201791C
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- radix angelicae
- zinc oxide
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to an external bonding medicine used for treating rheumatic diseases, a prescription thereof and a making method thereof, particularly to an external bonding paste used for dispelling wind and alleviating pain. The prescription comprises 10 portions of nux vomica, 7 portions of common monkshood mother root, 7 portions of doubleteeth pubesscent angelica root, 5 portions of ephedra, 5 portions of cassia twig, 3 portions of asarum, 5 portions of Radix Saposhnikoviae, 5 portions of angelica, 5 portions of safflower, 2 portions of dragon blood, 5 portions of frankincense, 5 portions of myrrh, 1 portion of camphor, 2 portions of borneol, 7 portions of rosin, 20 portions of zinc oxide. The making method comprises the following steps: (1) the first 9 kinds of herbs in the prescription are soaked in ethanol, and the effective components of water-solubility and fat-solubility components of the first 9 kinds of herbs in the prescription are extracted; (2)frankincense and myrrh are heated for taking oil; (3) substances obtained from (1) and (2) are mixed, and then, the camphor, the borneol, the rosin, the dragon blood and the zinc oxide are added in the mixed substance to form paste; (4)sheepskin or artificial sheepskin is used as backing materials to prepare the external bonding paste.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of rheumatism, specifically a kind of is the external application type unguentum of the wind-expelling pain-stopping of feedstock production with the Chinese herbal medicine, the invention still further relates to the manufacture method of this medicine.
Background technology
Rheumatism is commonly encountered diseases, the frequently-occurring disease of serious harm human health, be divided into kind more than 120 in the world, wherein modal is rheumatic arthritis, rheumatoid arthritis, ankylosing spondylitis and cold rheumatoid joint pain, harm is maximum, sickness rate is also high, clinical manifestation is swelling, the pain of tissue such as joint, muscle, flesh key, and inducement such as wind and cold rheumatism and outbreak repeatedly whenever is so that develop into the joint deformity disability.Many in recent years scholars further investigate the notion of this class disease, the cause of disease, pathology etc., obtain new progress, yet clinically still lack effective treatment means.The external application unguentum is one of traditional method of motherland's therapeutic treatment rheumatism, the history in existing several thousand, through constantly improving and development, form present a series of external application unguentum, mainly be divided into diachylon, rubber plaster, Colophonium cream three major types, existing three major types external application unguentum still has many deficiencies, manufacturing process as diachylon comprises the fried medical herbs of high temperature, concentrate, following Plumbum preparatium, water logging detoxification etc., the shortcoming of this process is the high temperature that needs in the process of boiling through more than 300 ℃, the effective ingredient of part medical herbs is ineffective because of high temperature cabonization, part effective ingredient generation oxidation operation, decompose and destroyed, part composition polymerization reaction take place is arranged again, be polymerized to macromolecular substances and be difficult for Transdermal absorption; Can produce again the prejudicial formaldehyde of skin, propylene etc.; Contain the lead element extremely harmful in the Plumbum preparatium to human body; Rubber plaster (yi zheng gao) is the new development of external application unguentum in modern age, and it is also convenient to use, but in content of dispersion very little, the efficacy of a drug too a little less than, the osmosis table is shallow, and the deep pathological changes is difficult to play effect.Colophonium cream is too hard, and is softening bad, pasting back uncomfortable.Therefore the external application unguentum is badly in need of further improving.Traditional in addition externally applied plaster thing prescription is formed complicated, and as dog skin plaster, panchrest plaster, ZHUIFENG GAO, drug prescription is according to clinical practice experience prescription by more than 20 flavors to 40 multi-flavor mostly, lacks the theory analysis of modern pharmacology and Chemistry for Chinese Traditional Medicine, haves much room for improvement.The main technical points that the outer emplastrum of above three major types is made is the formation of bonding agent and selects for use, as diachylon is the complex that spissated vegetable oil and Plumbum preparatium form under the high temperature, what rubber plaster was selected for use is natural rubber, what Colophonium cream was selected for use is natural rosin, the toxicity of Plumbum preparatium is self-evident, natural rubber be difficult to more medicine sticking and, natural rosin hardness under normal body temperature is bigger, so the improvement of bonding agent is the key problem in technology of external application unguentum.
The content of invention
The object of the present invention is to provide a kind of have wind-damp dispelling, diffusing ailment said due to cold or exposure, warming the meridian and promoting blood circulation, promoting blood circulation and stopping pain, improve the blood circulation of lesion, blood vessel dilating is eliminated spasm, regulates immunity, promote the reparation of damaged tissues, it is higher to include drug level, and action effective is lasting, and cohesiveness is good, the medicine nontoxic, that side effect is less.
Solution of the present invention is based on motherland's medical science to rheumatismal understanding and Therapeutic Principle, filters out the natural plant of expelling wind and dampness, promoting the flow of QI in the collateral by warming the meridian, promoting blood circulation and stopping pain from motherland's medicine treasure-house, by the theory of Chinese medical science prescription.Reach the dialectical purpose of controlling of executing.
According to the result of phytochemistry to Chinese herbal medicine analysis of effective component research, be that solvent extracts according to the water solublity and the fat-soluble employing Diluted Alcohol of these effective ingredient, though few to reach dose, and the higher purpose of effective ingredient concentration.
According to the construction features of skin, pore, sebum glandular orifice add short skin absorbent for absorbing the main thoroughfare of external used medicine, are beneficial to the fast Absorption of medicine.
Body temperature according to human body skin is 36 ℃-37 ℃, and the softening point of adjusting ointment is 25 ℃, and the sticking temperature thresholding is 30 ℃-45 ℃, and is close with body temperature, and the cohesiveness of outer plaster relies on body temperature and keeps.The temperature thresholding of softening point is to rely on the size of resinous, gummy drug ratio amount in the prescription to realize.
Breathability and the humidity required according to human body skin, selecting sheep close with human body or imitative sheep for use is the backing material, keeps good aeration and normal humidity, with flexibility and the comfortableness of keeping product of the present invention.
According to a kind of external plaster for the treatment of rheumatic arthralgia of the present invention, it is characterized in that making by following materials of weight proportions:
Semen Strychni 9-20 part, Radix Aconiti 4-15 part, Radix Angelicae Pubescentis 4-15 part, Herba Ephedrae 4-15 part, Ramulus Cinnamomi 4-15 part, Herba Asari 1-5 part, Radix Saposhnikoviae 4-15 part, Radix Angelicae Sinensis 4-10 part, Flos Carthami 4-10 part, Sanguis Draxonis 1-5 part, Olibanum 4-10 part, Myrrha 4-10 part, Camphora 0.5-1 part, Borneolum Syntheticum 1-3 part, Colophonium 4-10 part and zinc oxide 10-25 part.
External plaster according to another treatment rheumatic arthralgia of the present invention is characterized in that being made by following materials of weight proportions:
Semen Strychni 9-15 part, Radix Aconiti 4-10 part, Radix Angelicae Pubescentis 4-12 part, Herba Ephedrae 4-7 part, Ramulus Cinnamomi 4-7 part, Herba Asari 1-5 part, Radix Saposhnikoviae 4-7 part, Radix Angelicae Sinensis 4-7 part, Flos Carthami 4-7 part, Sanguis Draxonis 1-2 part, Olibanum 4-7 part, Myrrha 4-7 part, Camphora 1-2 part, Borneolum Syntheticum 1-3 part, Colophonium 4-7 part and zinc oxide 10-20 part.
According to another external plaster of the present invention, it is characterized in that making by following materials of weight proportions:
20 parts of 10 parts of Semen Strychni, 7 parts of Radix Aconitis, 7 parts of Radix Angelicae Pubescentiss, 5 parts in Herba Ephedrae, 5 parts of Ramulus Cinnamomi, 3 parts of Herba Asaris, 5 parts of Radix Saposhnikoviaes, 5 parts of Radix Angelicae Sinensis, 5 parts on Flos Carthami, 2 parts of Sanguis Draxonis, 5 parts of Olibanums, 5 parts of Myrrhas, 1 part of Camphora, 2 parts of Borneolum Syntheticums, 7 parts of Colophonium and zinc oxide.
According to the described external plaster of technique scheme, it is characterized in that: the backing material of external plaster is sheep or imitative sheep.
Preparation method according to the described external plaster of technique scheme is characterized in that: with Semen Strychni, Radix Aconiti, Radix Angelicae Pubescentis, Herba Ephedrae, Ramulus Cinnamomi, Herba Asari, Radix Saposhnikoviae, Radix Angelicae Sinensis and Flos Carthami soak with ethanol effective component extracting, through reclaim pure extractum; Olibanum and Myrrha heated get oil; With pure extractum and oil camphorate after miscible, Borneolum Syntheticum, Colophonium, Sanguis Draxonis and zinc oxide make ointment; The softening point of adjusting ointment is 25 ℃, and the sticking temperature thresholding is 30-45 ℃; The cream of getting it filled is even to be spread out on the backing material, makes external plaster.
The objective of the invention is to realize by following proposal:
(1) medicine of the present invention is made (consumption is a weight portion) by following component:
Semen Strychni 9-20 part Radix Aconiti 4-15 part Radix Angelicae Pubescentis 4-15 part
Herba Ephedrae 4-15 part Ramulus Cinnamomi 4-15 part Herba Asari 1-5 part
Radix Saposhnikoviae 4-15 part Radix Angelicae Sinensis 4-10 part Flos Carthami 4-10 part
Sanguis Draxonis 1-5 part Olibanum 4-10 part Myrrha 4-10 part
Camphora 0.5-1 part Borneolum Syntheticum 1-3 part Colophonium 4-10 part
Zinc oxide 10-25 part
(2) square medicine is formed and function
Traditional Chinese medical science science thinks that the etiology and pathogenesis of rheumatism mostly is the evil stasis of blood resistance meridians of cold-damp, so wind-expelling pain-stopping cream cube with remove wind prevailing over dampness, temperature three-way meridian is a method, expelling wind and dampness such as Semen Strychni, Radix Aconiti, Radix Angelicae Pubescentis, Herba Ephedrae, Ramulus Cinnamomi, Herba Asari in the side, Radix Angelicae Sinensis, Flos Carthami promoting blood circulation to remove obstruction in the collateral, Sanguis Draxonis, Olibanum, Myrrha promoting blood circulation and stopping pain, Borneolum Syntheticum, Camphora understand things pain-stopping, Colophonium dispelling the wind and dampness pathogens pruritus.
(3) the formula optimization weight proportion scope of preparation medicine of the present invention is:
Semen Strychni 9---12 parts of 15 portions of Radix Aconitis 4---10 parts of Radix Angelicae Pubescentiss 4---
Herba Ephedrae 4---5 parts of 7 parts of Ramulus Cinnamomi 4---7 parts of Herba Asaris 1---
Radix Saposhnikoviae 4---7 parts of 7 parts of Radix Angelicae Sinensis 4---7 parts of Flos Carthamis 4---
Sanguis Draxonis 1---7 parts of 2 parts of Olibanums 4---7 parts of Myrrhas 4---
Camphora 1---7 parts of 2 parts of Borneolum Syntheticums 1---3 parts of Colophonium 4---
Zinc oxide 10---20 parts
(4) the optimum weight proportioning of medicine of the present invention is:
7 parts of 7 parts of Radix Angelicae Pubescentiss of 10 portions of Radix Aconitis of Semen Strychni
3 parts of 5 parts of Herba Asaris of 5 parts of Ramulus Cinnamomi of Herba Ephedrae
5 parts on 5 parts of Flos Carthamis of 5 parts of Radix Angelicae Sinensis of Radix Saposhnikoviae
5 parts of 5 parts of Myrrhas of 2 parts of Olibanums of Sanguis Draxonis
7 parts of 2 parts of Colophonium of 1 part of Borneolum Syntheticum of Camphora
20 parts of zinc oxide
(5) production process of this wind-expelling pain-stopping cream:
1. Semen Strychni, Radix Aconiti, Radix Angelicae Pubescentis, Herba Ephedrae, Ramulus Cinnamomi, Herba Asari, Radix Saposhnikoviae, Radix Angelicae Sinensis, Flos Carthami are pulverized and be coarse powder, with 75%---95% soak with ethanol was got filtrate more than 24 hours, and medicinal residues extract 3 times more repeatedly, merge ethanol extract, decompression recycling ethanol does not promptly get pure extractum to there being vinosity.
2. Olibanum, Myrrha are heated to getting oil more than 150 ℃.
3. above both miscible backs are added zinc oxide.
4. add Sanguis Draxonis, Camphora, Borneolum Syntheticum is miscible leaves standstill.
5. get 6---20 grams are even to be spread out in the backing material.The backing material can be selected sheep or imitative sheep for use.
(6) important feature of the present invention is:
1. used medicine is without high-temperature process (as fried), and effective ingredient can be by carbonization, can be and lost efficacy in oxidation under the hot conditions, decomposition, and can not produce repolymerization and be reacted into to being difficult to larger molecular organics by skin pore, sebum glandular orifice.
2. this medicine has been avoided the infringement of lead element to human body without the Plumbum preparatium.
3. this medicine is a raw material for the pure natural plant medical material, uses alcohol extracting method and extracts its water solublity and fat-soluble two effective constituents, and it is superior that more traditional diachylon application frying method extracts liposoluble constituent merely.
4. effective ingredient concentration is higher relatively, and efficacy of a drug effect is stronger relatively, and it is lasting to keep action time.
5. softening point of the present invention is at 25 ℃, it below 25 ℃ plaster, desaturation is o'clock at 50 ℃, become rare thick paste more than 50 ℃, the sticky limit step-down, 30 ℃ of---45 ℃ sticky limit is 3---8kg, close with 37 ℃ of human body normal body temperatures, paste back dependence body temperature and keeping its softening point and moderate sticky limit.Softening point and sticky limit are to rely on the proportional quantity that contains each medicine of natural resin in the prescription to finish.
6. another characteristics of the present invention are that to select sheep or imitative sheep for use be the backing material, and permeability and human body skin are close, keeping pasting normal humidity and the breathability of locating, with the flexibility that keeps ointment with pasting the comfortableness of locating skin.
7. this ointment is water insoluble, not influenced by perspiration, and the water operation does not come off under the band ointment.
8. this product character is stable, can use repeatedly.
(7) scope of application of wind-expelling pain-stopping cream: be mainly used in back, neck shoulder, the tingle distending pain of extremities joint that rheumatism causes, comprise cold rheumatoid joint pain, rheumatic arthritis, rheumatoid arthritis, ankylosing arthritis, muscle fiber is knitted inflammation, muscular strain pain, the chronic pain that facial neuritis and osteopatia sprain cause, hepatocarcinoma pain, carcinous bone shifts pain etc.
The specific embodiment
(1) making of wind-expelling pain-stopping cream
Weigh Semen Strychni 30 grams, Radix Aconiti 15 grams, Radix Angelicae Pubescentis 15 grams, Herba Ephedrae 15 grams, Ramulus Cinnamomi 15 grams by above-mentioned formula proportion, Herba Asari 9 grams, Radix Saposhnikoviae 10 grams, Radix Angelicae Sinensis 9 grams, Flos Carthami 10 grams, Sanguis Draxonis 3 grams, Olibanum 10 grams, Myrrha 10 grams, Camphora 2 grams, Borneolum Syntheticum 3 grams, Colophonium 18 grams, zinc oxide 30 grams.The acidic ethanol that is 3-5,60---80% with PH with preceding 9 flavor medicines soaked more than 15 days, got its extractum, heated with Olibanum, Myrrha and got its oil, add Sanguis Draxonis, Camphora, Borneolum Syntheticum then, Colophonium, zinc oxide become cream, get an amount of even the stand on the backing material, make wind-expelling pain-stopping cream of the present invention.
(2) drug efficacy study
Semen Strychni is arranged in this prescription, medicine fractional analysis Semen Strychni main component is strychnine (Strychnine) and brucine (Brucine), strychnine can optionally excited spinal cord, excessive meeting causes toxic reactions such as tic, the effect of brucine and strychnine is similar and action intensity has only the former 1/40, so the toxicity of Semen Strychni mainly is the toxicity of strychnine, though the used Semen Strychni of this medicine is external, but it is also very important, in order to determine safe and effective dosage, once consulted document as a means of reference: clear " surgery is given birth to collection entirely " treatment arthralgia, contain every dose of 0.875g of Semen Strychni amount in the compound recipe, amount to strychnine 10.06mg.Proved recipe dispelling wind Pain-Stopping Pill oral medication joint rheumatism, every ball gross weight 6.00g amounts to strychnine 11.93mg.This medicine contains Semen Strychni crude drug 1.5-3g for every dose, amounts to strychnine 1.42-2.84mg, and long-term the sight looked into non-toxic reaction.
Radix Aconiti contains aconitine, hypaconitine, mesaconitine, effect with remarkable blood vessel dilating and local narcotic analgesic, toxicity is extremely strong, oral ingestion dosage is 0.2mg, toxicity after the process of preparing Chinese medicine reduces by 81.3%, this medicine adopts Radix Aconiti Preparata, and every agent content is 1/50 of an oral dose, can not produce toxic reaction.
Herba Asari, Ramulus Cinnamomi contain identical volatile oil, and main component of essential oil is methyleugenol (accounting for 50%), eugenol, safrole etc., and the part is had anesthesia, analgesic activity.
Olibanum is the gum resin of olive subject plant Boswellia carterii Birdw, resinous 60-70%, and gummy 27-35%, volatile oil 3-8%, the main component of resin is free α, β-boswellic acid 33%, natural gum is the calcium salt and the magnesium salt 20% of arabitic acid, bassorin 6%.
Myrrha is the gum resin of olive subject plant myrrh or Alan's fort myrrh, and the resinous 25-35% of myrrh contains volatile oil, eugenol in the resin, gummy 57-65%.
Sanguis Draxonis is the resin in babassu Sanguis Draxonis fruit and the trunk, is the mixture of resin ester and resinotannol.
Radix Angelicae Pubescentis, Radix Saposhnikoviae, Radix Angelicae Sinensis contain angelol, angelic acid, angelicin and have blood vessel dilating, analgesia, antiphlogistic effect.
Herba Ephedrae contains ephedrine and pseudo-ephedrine, skeletal muscle there is antifatigue effect, can promote by the conduction between the neuromuscular that curare suppressed, can be used for Therapy for Myasthemia Gravis, the action principle of ephedrine belongs to mixed type, major part is the direct effect that produces owing to the adrenoreceptor combination, and fraction is owing to promote the indirect action that medium discharges.
Borneolum Syntheticum, Camphora are resin and the volatile oil of borneo camphor tree and Lignum cinnamomi camphorae, and there are analgesia, itching-relieving action in the part.
Colophonium is the resin of Pinus tabuliformis and Pinus massoniana Lamb, and it is about 80% to contain abietic anhydride and rosin acid, and volatile oil 0.5% has the granulation promoting pain relieving, anti rheumatism action.
(3) diagnostic criteria: the rheumatic four diseases diagnostic criteria of formulating with the national combination of Chinese and Western medicine rheumatism academic conference of first of holding in Kunming in April, 1988, with reference to nineteen eighty-three Americanism damp disease association to rheumatismal diagnostic criteria.
(4) criterion of therapeutical effect: the rheumatic four diseases criterion of therapeutical effect is judged according in April, 1988 whole nation first combination of Chinese and Western medicine rheumatism academic conference, the rheumatic arthralgia criterion of therapeutical effect is: cure in the recent period, get involved after treatment joint, myalgia disappears, joint function recovery is normal, and erythrocyte sedimentation rate fast person reduce to normally.Produce effects: the pain of joint muscle major part of getting involved disappears or obviously alleviates, and it is normal that erythrocyte sedimentation rate recovers.Effectively: the pain of joint muscle or swell and ache and take a favorable turn of after treatment, getting involved.Invalid: through treating 1---the joint symptom of getting involved after 2 courses of treatment (15 days) does not have improvement.
(5) therapeutic outcome: 396 routine rheumatisant results are as follows in clinical observation: cold rheumatoid joint pain 337 examples, cure 272 examples in the recent period, produce effects 35 examples, effective 24 examples, invalid 6 examples, total effective rate 98.2%.Rheumatic arthritis 38 examples, effective 21 examples, effective percentage 55.3%.Rheumatoid arthritis 21 examples, effective 11 examples, effective percentage 52.4%.The result shows that the present invention is to cold rheumatoid joint pain effect best (P＜0.01).
Preference
Example one: open * *, woman, 42 years old, suffered from pain in the shoulder and back 3 years, tired whenever, cloudy day rains, cold-damp and the swelling and pain that shows effect repeatedly, heavy plate, joint stuffiness, each outbreak position is fixed, the time heavy when light, local muscle spasm, through having a rest, physical therapy, treatments such as acupuncture cupping can be alleviated, with the passing of time touching, experience all sorts of and do not heal, erythrocyte sedimentation rate is normal on inspection, anti-" 0 ", rheumatoid factor negative, be diagnosed as " cold rheumatoid joint pain ", " muscle fiber is knitted inflammation ", " omoplate around scorching " etc. is through with wind-expelling pain-stopping cream sx after a day, transference cure after one week, pain degree obviously alleviates when showing effect once more, and is continuous with one week of this cream, and logotype is thoroughly cured for three times.
Example two: poplar * *, the man, 50 years old,, can not walk because of the following water operation fatigue tingle distending pain of low back lower limb of catching cold, because of pain can not be fallen asleep unbearably, stand up difficulty, be diagnosed as " rheumatic lumbago and scelalgia ", through not alleviating with antirheumatic and external application plaster for injury and rheumatism, pain disappears after using this wind-expelling pain-stopping cream, and is respond well.
Example three: the king * *, the man, 50 years old, burst lumbago and skelalgia 3 months can not be upright, and difficulty in walking is diagnosed as intervertebral disc prolapse through CT examination, through failing to respond to any medical treatment with methods such as reduction by tractions, disappears through pasting with pain behind the wind-expelling pain-stopping cream three times, and is as usual on foot.
Claims (5)
1, a kind of external plaster for the treatment of rheumatic arthralgia is characterized in that being made by following materials of weight proportions:
Semen Strychni 9-20 part, Radix Aconiti 4-15 part, Radix Angelicae Pubescentis 4-15 part, Herba Ephedrae 4-15 part, Ramulus Cinnamomi 4-15 part, Herba Asari 1-5 part, Radix Saposhnikoviae 4-15 part, Radix Angelicae Sinensis 4-10 part, Flos Carthami 4-10 part, Sanguis Draxonis 1-5 part, Olibanum 4-10 part, Myrrha 4-10 part, Camphora 0.5-1 part, Borneolum Syntheticum 1-3 part, Colophonium 4-10 part and zinc oxide 10-25 part.
2, a kind of external plaster for the treatment of rheumatic arthralgia is characterized in that being made by following materials of weight proportions:
Semen Strychni 9-15 part, Radix Aconiti 4-10 part, Radix Angelicae Pubescentis 4-12 part, Herba Ephedrae 4-7 part, Ramulus Cinnamomi 4-7 part, Herba Asari 1-5 part, Radix Saposhnikoviae 4-7 part, Radix Angelicae Sinensis 4-7 part, Flos Carthami 4-7 part, Sanguis Draxonis 1-2 part, Olibanum 4-7 part, Myrrha 4-7 part, Camphora 1-2 part, Borneolum Syntheticum 1-3 part, Colophonium 4-7 part and zinc oxide 10-20 part.
3, external plaster according to claim 2 is characterized in that being made by following materials of weight proportions:
10 parts of Semen Strychni, 7 parts of Radix Aconitis, 7 parts of Radix Angelicae Pubescentiss, 5 parts in Herba Ephedrae, 5 parts of Ramulus Cinnamomi,
3 parts of Herba Asaris, 5 parts of Radix Saposhnikoviaes, 5 parts of Radix Angelicae Sinensis, 5 parts on Flos Carthami, 2 parts of Sanguis Draxonis,
5 parts of Olibanums, 5 parts of Myrrhas, 1 part of Camphora, 2 parts of Borneolum Syntheticums, 7 parts of Colophonium
With 20 parts of zinc oxide.
4, according to claim 1,2 or 3 described external plasters, it is characterized in that:
The backing material of external plaster is sheep or imitative sheep.
5, according to the preparation method of claim 1,2 or 3 described external plasters, it is characterized in that:
With Semen Strychni, Radix Aconiti, Radix Angelicae Pubescentis, Herba Ephedrae, Ramulus Cinnamomi, Herba Asari, Radix Saposhnikoviae, Radix Angelicae Sinensis and Flos Carthami soak with ethanol effective component extracting, through reclaim pure extractum;
Olibanum and Myrrha heated get oil;
With pure extractum and oil camphorate after miscible, Borneolum Syntheticum, Colophonium, Sanguis Draxonis and zinc oxide make ointment;
The softening point of adjusting ointment is 25 ℃, and the sticking temperature thresholding is 30-45 ℃;
The cream of getting it filled is even to be spread out on the backing material, makes external plaster.
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| CN 03105156 CN1201791C (en) | 2003-03-06 | 2003-03-06 | Wind dispelling and pain relieving ointment |
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| CN 03105156 CN1201791C (en) | 2003-03-06 | 2003-03-06 | Wind dispelling and pain relieving ointment |
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| CN1201791C true CN1201791C (en) | 2005-05-18 |
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| CN105963407A (en) * | 2016-06-24 | 2016-09-28 | 无锡市中医医院 | Paste capable of activating meridians to stop pain as well as preparation method and application of paste |
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