CN109700856A - A kind of Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons - Google Patents
A kind of Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine external prescriptions relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons, are mainly made of the bulk pharmaceutical chemicals that following weight matches: 15-30 parts of folium artemisiae argyi, 12-20 parts of ramulus cinnamomi, 15-30 parts of safflower, 15-30 parts of Radix Angelicae Sinensis, 15-30 parts of Cortex Eucommiae, 9-25 parts of herba taxilli, 9-12 parts of Rhizoma Chuanxiong, 6-12 parts of rhizoma corydalis, 1-5 parts of menthol, 1-3 parts of vanillyl butyl ether.Compared with existing product, the Chinese medicine external compatibility of medicines in a prescription disclosed by the invention follows " monarch " principle, treating both manifestation and root cause of disease, and utilize modern extraction technique, merge small-molecule active substance, enhance subcutaneous tissue penetration, analgesia promoting blood circulation effect can be generated in a short time by making Chinese medicine external prescription not only, and chin or cheek nourishing liver and kidney can be reached, the effect of reconciliation muscles and bones, there is significant curative effect to rheumatisms such as gonitis, cervical spondylosis, scapulohumeral periarthritis, lumbar vertebrae shoulder disks, achieve the purpose that rheumatism is thoroughly eradicated conducive to by the conditioning to inside of human body function.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines more particularly to a kind of Chinese medicine external sides relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons
Agent.
Background technique
Rheumatism is clinical common frequently-occurring disease, is typically due to human body machine table or channels and collaterals by wind, cold, wet, thermal conductivity and causes limb
There is tingle, pain, swelling in body joint, muscle and muscles and bones, or even cause anchylosis, numbness, deformity or injure the diseases such as internal organs
Shape.The stubborn diseases such as gonitis, cervical spondylosis, scapulohumeral periarthritis, lumbar vertebrae shoulder disk belong to cold-dampness type rheumatism more.
As Internet technology continues to develop, mobile phone and computer have become in recent years people's work and life can not or
Scarce a part, " computer family " or " family of bowing " become social normality, and for a long time with anchor operate computer or
Mobile phone can cause chronic fatigue syndrome, and body is caused to be in sub-health state.It investigates and shows according to the Ministry of Public Health, in recent years cervical vertebra
In the patient of the cold-dampness types rheumatism such as disease, scapulohumeral periarthritis mostly based on the young and the middle aged, have statistics display patient with cervical Spondylopathy in nearly 70% be city
White collar, and in patient with cervical Spondylopathy 48% be 40 years old the young and the middle aged below, this indicates that the cold-dampness types rheumatism such as cervical spondylosis, scapulohumeral periarthritis
Patient groups gradually tend to rejuvenation, not only bring pain to people's lives, also cause centainly to the labour and production of society
Loss.
Currently, the treatment for numbness pains such as rheumatalgia, knee numbness, scapulohumeral periarthritis, cervical spondylosiss, existing product type in the market
Various, curative effect is different.Doctor trained in Western medicine mostly uses the conventional means such as anti-inflammation analgesia medicine, microwave electrotherapy or operative treatment, generally takes height, wound
Wound is big, and palliative.Chinese medicine mostly uses acupuncture, traction, massage, massage, stifling, oral medicinal herb and the means such as controls outside.Its
In, though acupuncture, traction, massage, massage, it is stifling can effective swelling and pain relieving still have some deficits for restoring soft tissue function, and
The course for the treatment of is longer；And there is a certain security risk for oral medicinal herb, though external therapy of Chinese herb such as exterior-applied medical wine etc. has stronger subcutaneous group
Penetration is knitted, but it is fast to volatilize, stimulation is big, and curative effect is weak.
Summary of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of Chinese medicine external sides relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons
Agent, in the formula of the exterior-applied prescription containing folium artemisiae argyi, ramulus cinnamomi, safflower, Radix Angelicae Sinensis, Cortex Eucommiae, herba taxilli, Rhizoma Chuanxiong, rhizoma corydalis, menthol and
Vanillyl butyl ether has effects that obvious promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons analgesic, can effectively treat gonitis, cervical spondylosis, shoulder
The intractables cold-dampness paralysis such as inflammation, lumbar vertebrae shoulder disk, conducive to treating both manifestation and root cause of disease is achieved the purpose that.
In order to solve the above-mentioned technical problem, the present invention realizes by the following technical programs:
Chinese medicine that traditional Chinese medicinal components of the present invention can be had same or similar effect replaces, and these medicinal materials can be according to
" national Chinese medicine preparation specification " or " dictionary of medicinal plant " are processed.
A kind of Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons, the Chinese medicine external prescription is mainly by following heavy
The bulk pharmaceutical chemicals composition of amount proportion: 15-30 parts of folium artemisiae argyi, 12-20 parts of ramulus cinnamomi, 15-30 parts of safflower, 15-30 parts of Radix Angelicae Sinensis, Cortex Eucommiae 15-30
Part, 9-25 parts of herba taxilli, 9-12 parts of Rhizoma Chuanxiong, 6-12 parts of rhizoma corydalis, 1-5 parts of menthol, 1-3 parts of vanillyl butyl ether.
Further, the Chinese medicine external prescription is mainly made of the bulk pharmaceutical chemicals that following weight matches: 20-25 parts of folium artemisiae argyi,
15-17 parts of ramulus cinnamomi, 20-25 parts of Radix Angelicae Sinensis, 20-25 parts of Cortex Eucommiae, 14-20 parts of herba taxilli, 10-11 parts of Rhizoma Chuanxiong, prolongs 20-25 parts of safflower
8-10 parts of Hu rope, 2-4 parts of menthol, 1.5-2.5 parts of vanillyl butyl ether.
Further, the Chinese medicine external prescription is mainly made of the bulk pharmaceutical chemicals that following weight matches: 22 parts of folium artemisiae argyi, ramulus cinnamomi
16 parts, 22 parts of safflower, 22 parts of Radix Angelicae Sinensis, 22 parts of Cortex Eucommiae, 17 parts of herba taxilli, 10.5 parts of Rhizoma Chuanxiong, 9 parts of rhizoma corydalis, 3 parts of menthol, perfume
2 parts of blue base butyl ether.
Further, the Chinese medicine external prescription is mainly made of the bulk pharmaceutical chemicals that following weight matches: 25 parts of folium artemisiae argyi, ramulus cinnamomi
20 parts, 25 parts of safflower, 20 parts of Radix Angelicae Sinensis, 25 parts of Cortex Eucommiae, 20 parts of herba taxilli, 12 parts of Rhizoma Chuanxiong, 9 parts of rhizoma corydalis, 1.5 parts of menthol, perfume
1 part of blue base butyl ether.
A kind of preparation method of the Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons, includes the following steps:
(1) appropriate folium artemisiae argyi, ramulus cinnamomi, safflower, Radix Angelicae Sinensis, Cortex Eucommiae, herba taxilli, Rhizoma Chuanxiong, rhizoma corydalis are weighed and is respectively crushed into coarse powder, is mixed
Mixed-powder is formed after uniformly, it is spare；
(2) mixed-powder deionized water heating and refluxing extraction obtained by step (1), Extracting temperature are 80-100 DEG C, extraction time
At least 2 times, 1-2 hours each, extracting solution merges filtering, recycles deionized water, obtains filtrate, spare；
(3) gained filtrate obtains mixing Chinese medicine extract after strainer filtering in step (2), spare；
(4) suitable menthol and vanillyl butyl ether are sequentially added in the mixing Chinese medicine extract in step (3), stirring is equal
Finished product medicament is obtained after even.
Further, filtrate described in step (3) successively passes through the strainer of 20 mesh, 40 mesh, 100 mesh, 200 mesh and 400 mesh
Filtering.
Further, vanillyl butyl ether described in step (4) is obtained by supercritical extraction.
Further, the weight ratio of deionized water described in step (2) and mixed-powder is 10-30.
Further, in step (2), extraction time is 3 times, and extraction time first time is 2 hours, second of extraction time
It is 1 hour, third time extraction time is 1 hour.
Application method: prepared Chinese medicine external prescription is applied to painful area, is massaged into until fully absorbing, daily
2-3 times.
The selected traditional Chinese medicinal components of the present invention can be by commercially available, and pharmacological property and effect are as follows:
Folium artemisiae argyi: its is warm-natured, and bitter returns liver,spleen,kidney to pass through, the property of pure sun, and logical 12 warp walks three yin；Fragrant temperature dissipates, and can rise can drop,
There are warming channel for arresting bleeding, eliminating cold to stop pain, removing dampness to stop itchin and other effects.
Ramulus cinnamomi: acrid flavour temperature is apt to wind-dispelling by cold, warming meridian, to cold-damp rheumatoid arthrosis disadvantage pain, menostasis, dysmenorrhea, phlegm retention
Equal diseases have therapeutic effect.
Safflower: acrid flavour, warm-natured, converge to heart and liver channels, main blood circulation, removing blood stasis and acesodyne are drug for invigorating blood circulation and eliminating stasis traditional simply,
Clinically it is commonly used for treating acute and chronic muscular strain, traumatic injury, carbuncle swells silt pain.
Radix Angelicae Sinensis: it is sweet in flavor, pungent, it is warm-natured, return liver, the heart, the spleen channel, all pains of swelling from head to foot, blood vessels discord, mend five Tibetan, raw muscle can be controlled
Bone, ease constipation stomach.
Cortex Eucommiae: acrid flavour, sweet, the flat temperature of gas enters liver and kidney channel, nourishing liver and kidney, strengthening the bones and muscles, main waist and knee especially cannot bend pain in the loins
The person of stretching has special effect.
Herba taxilli: hardship is put down nontoxic, returns liver and kidney channel, is played the role of nourishing liver and kidney, is helped muscles and bones, beneficial blood vessels, miscarriage prevention member, to rheumatism
Numbness pain, kidney deficiency and liver, soreness of waist and knee joint, muscles and bones inability person are especially suitable for.
Rhizoma Chuanxiong: temperature, acrid flavour return liver, gallbladder, pericardium channel, and main apoplexy enters brain headache, arthritis muscle contraction, is apt to blood-activating and qi-promoting, relaxing muscles and tendons
Analgesic.
Rhizoma corydalis: temperature, acrid flavour return liver, the spleen channel, have promoting blood circulation, promoting the circulation of qi, analgesic the effect of, for chest side of body, epigastric pain,
Chest impediment and cardialgia, amenorrhea and algomenorrhea, postpartum stasis, tumbling and swelling.
Menthol: the main component of peppermint, have special fragrance, cool feeling, be widely used in medicine wind dispelling, anti-corrosion,
In addition anti-inflammatory, analgesia, antipruritic etc. also have apparent transdermal rush infiltration effect.
Vanillyl butyl ether: small molecule active object after acting locally on skin, can quickly generate mild lasting pyrogen effect
It answers, including accelerates microcirculation, stimulation subcutaneous fat is metabolized, and is promoted capillary blood circulation, is promoted the suction of effective component in drug
Receive etc..
"Nei Jing" has cloud " wet three gas of chill is miscellaneous extremely, combined into numbness "；" General Treatise on the Cause and Symptoms of Diseases " is pointed out: " deficiency of kidney-QI, by ailment said due to cold or exposure
So-called, internal lesion caused by overexertion then kidney deficiency, it is empty then by with it is air-cooled, it is air-cooled to be striven with healthy tendency friendship, therefore lumbar and pedal pain ", it is seen that the cause of disease of disadvantage is kidney deficiency
For this, cold-evil is mark.Folium artemisiae argyi in Chinese medicine external prescription disclosed by the invention, ramulus cinnamomi is warming channel and expelling cold, clearing damp eliminating impediment, safflower, Radix Angelicae Sinensis
Promoting blood circulation and stopping pain, Cortex Eucommiae, herba taxilli tonifying liver and kidney and strengthening bones and muscles, assistant are helped with Rhizoma Chuanxiong, rhizoma corydalis promoting qi circulation and relieving pain, menthol sedation-analgesia
Drug absorption, and vanillyl butyl ether can play collaboration and promote microcirculation and Transdermal absorption, can make spreader portion when in use
The experience of ice fire is built in position fever altogether together with menthol.
Compared with existing product, the Chinese medicine external compatibility of medicines in a prescription disclosed by the invention follows " monarch " principle, and sample is simultaneous
It controls, and utilizes modern extraction technique, merge small-molecule active substance, enhance subcutaneous tissue penetration, make Chinese medicine external prescription
Analgesia promoting blood circulation effect can be not only generated in a short time, and can reach chin or cheek nourishing liver and kidney, reconciles the effect of muscles and bones, to knee joint
The rheumatisms such as inflammation, cervical spondylosis, scapulohumeral periarthritis, lumbar vertebrae shoulder disk have significant curative effect, reach conducive to by the conditioning to inside of human body function
The purpose that rheumatism is thoroughly eradicated.In addition, Chinese medicine external prescription preparing process disclosed by the invention is simple, has no toxic side effect, uses
Convenient, quick, cure rate is high, and uneasy to recur.
Present inventor, which passes through, carries out clinical trial to 800 many cases patient with cervical Spondylopathy, can reach within medication 2-3 weeks and fullys recover from an illness
More therapeutic effect, total effective rate maintain essentially in 65% or more, and cure rate is up to 50% or more, and schedules to last to above-mentioned case
Tracking in 2 years is not recurred again after finding most patient's recoveries from illness, and radical cure effect is obvious.
Typical case:
Patient Liu, female, 55 years old, plant operation worker, with cervical spondylosis be up to 3 years, patient occur nape pain, upper limb without
Power, finger be numb, the symptoms such as dizzy, uses multiple therapy methods instead in past therapeutic process without obtaining significant curative effect,
Be applied to painful area with Chinese medicine external prescription of the invention, each medication, which is massaged into, to be fully absorbed, medication after two weeks, pain and
Dizzy symptom completely eliminates, upper myasthenia of limbs and finger is numb is obviously slowed down, medication after three weeks, upper myasthenia of limbs and finger hair
The symptom eliminates of fiber crops, patient body state are significantly restored, and track 2 years without recurrence, and therapeutic effect is obvious.
Specific embodiment
For the ease of it will be understood by those skilled in the art that, the present invention is further explained in the light of specific embodiments,
The content that embodiment refers to is not delimit the scope of the invention.
Embodiment 1
A kind of Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons is present embodiments provided, the Chinese medicine external prescription is straight
It connects and is applied to painful area, be massaged into and fully absorb, daily medication 2-3 times is adhered to can reach therapeutic effect in medication 2-3 weeks.
The present embodiment is equipped with test group and control group, and the specific formula difference of test group and control group is as follows:
The Chinese medicine external prescription of test group 1, the component containing following parts by weight:
15 parts of folium artemisiae argyi, 12 parts of ramulus cinnamomi, 15 parts of safflower, 15 parts of Radix Angelicae Sinensis, 15 parts of Cortex Eucommiae, 9 parts of herba taxilli, 9 parts of Rhizoma Chuanxiong, 6 parts of rhizoma corydalis,
1 part of menthol, 1 part of vanillyl butyl ether.
The Chinese medicine external prescription of test group 2, the component containing following parts by weight:
20 parts of folium artemisiae argyi, 15 parts of ramulus cinnamomi, 20 parts of safflower, 20 parts of Radix Angelicae Sinensis, 20 parts of Cortex Eucommiae, 14 parts of herba taxilli, 10 parts of Rhizoma Chuanxiong, rhizoma corydalis 8
Part, 2 parts of menthol, 1.5 parts of vanillyl butyl ether.
The Chinese medicine external prescription of test group 3, the component containing following parts by weight:
22 parts of folium artemisiae argyi, 16 parts of ramulus cinnamomi, 22 parts of safflower, 22 parts of Radix Angelicae Sinensis, 22 parts of Cortex Eucommiae, 17 parts of herba taxilli, 10.5 parts of Rhizoma Chuanxiong, rhizoma corydalis
9 parts, 3 parts of menthol, 2 parts of vanillyl butyl ether.
The Chinese medicine external prescription of test group 4, the component containing following parts by weight:
25 parts of folium artemisiae argyi, 17 parts of ramulus cinnamomi, 25 parts of safflower, 25 parts of Radix Angelicae Sinensis, 25 parts of Cortex Eucommiae, 20 parts of herba taxilli, 11 parts of Rhizoma Chuanxiong, rhizoma corydalis 10
Part, 4 parts of menthol, 2.5 parts of vanillyl butyl ether.
The Chinese medicine external prescription of test group 5, the component containing following parts by weight:
30 parts of folium artemisiae argyi, 20 parts of ramulus cinnamomi, 30 parts of safflower, 30 parts of Radix Angelicae Sinensis, 30 parts of Cortex Eucommiae, 25 parts of herba taxilli, 12 parts of Rhizoma Chuanxiong, rhizoma corydalis 12
Part, 5 parts of menthol, 3 parts of vanillyl butyl ether.
The Chinese medicine external prescription of test group 6, the component containing following parts by weight:
30 parts of folium artemisiae argyi, 20 parts of ramulus cinnamomi, 30 parts of safflower, 30 parts of Radix Angelicae Sinensis, 30 parts of Cortex Eucommiae, 25 parts of herba taxilli, 12 parts of Rhizoma Chuanxiong, rhizoma corydalis 12
Part, 3 parts of menthol, 2 parts of vanillyl butyl ether.
The Chinese medicine external prescription of test group 7, the component containing following parts by weight:
25 parts of folium artemisiae argyi, 20 parts of ramulus cinnamomi, 25 parts of safflower, 20 parts of Radix Angelicae Sinensis, 25 parts of Cortex Eucommiae, 20 parts of herba taxilli, 12 parts of Rhizoma Chuanxiong, rhizoma corydalis 9
Part, 1.5 parts of menthol, 1 part of vanillyl butyl ether.
The Chinese medicine external prescription of test group 1-7 is prepared via a method which:
(1) appropriate folium artemisiae argyi, ramulus cinnamomi, safflower, Radix Angelicae Sinensis, Cortex Eucommiae, herba taxilli, Rhizoma Chuanxiong, rhizoma corydalis are weighed and is respectively crushed into coarse powder, is mixed
Mixed-powder is formed after uniformly, it is spare；
(2) mixed-powder deionized water heating and refluxing extraction obtained by step (1), the weight ratio of deionized water and mixed-powder
It is 30, Extracting temperature is 80 DEG C, and extraction time is 2 times, i.e., the filter residue obtained after extracting for the first time repeats to extract 1 time, is mentioned for the first time
Taking the time is 2 hours, and second of extraction time is 1 hour, and 2 extracting solutions are merged filtering, deionized water is recycled, is filtered
Liquid, it is spare；
(3) in step (2) gained filtrate successively after the strainer filtering of 20 mesh, 40 mesh, 100 mesh, 200 mesh and 400 mesh to get
Mix Chinese medicine extract；
(4) suitable menthol and vanillyl butyl ether are sequentially added in the mixing Chinese medicine extract in step (3), stirring is equal
Finished product medicament is obtained after even.
Wherein, the vanillyl butyl ether is obtained by supercritical extraction.
The Chinese medicine external prescription of control group 1, the component containing following parts by weight:
25 parts of folium artemisiae argyi, 20 parts of ramulus cinnamomi, 25 parts of safflower, 20 parts of Radix Angelicae Sinensis, 25 parts of Cortex Eucommiae, 20 parts of herba taxilli, 12 parts of Rhizoma Chuanxiong, rhizoma corydalis 9
Part, 1.5 parts of menthol.I.e. control group 1 is removed without containing the vanillyl butyl ether in test group 7, other compositions and content with examination
It is identical to test group 7.
The Chinese medicine external prescription of control group 2, the component containing following parts by weight:
25 parts of folium artemisiae argyi, 20 parts of ramulus cinnamomi, 25 parts of safflower, 20 parts of Radix Angelicae Sinensis, 25 parts of Cortex Eucommiae, 20 parts of herba taxilli, 12 parts of Rhizoma Chuanxiong, rhizoma corydalis 9
Part, 1 part of vanillyl butyl ether.I.e. control group 2 is removed without containing the menthol in test group 7, other compositions and content with test
Group 7 is identical.
The Chinese medicine external prescription preparation method of control group 1 and control group 2 is similar with test group 1-7 Chinese medicine external prescription,
This will not be repeated here.
270 patient with cervical Spondylopathy are chosen as subjects, are randomly divided into 9 groups, examination is respectively adopted in every group of 30 people, 1-7 group
Chinese medicine external prescription prepared by group 1-7 is tested, 8 groups and 9 groups are respectively adopted control group 1 and the preparation-obtained Chinese medicine of control group 2
Exterior-applied prescription.All patients are carried out with treatment in three weeks by a definite date, daily medication three times, smears the use of Chinese medicine external prescription every time
Amount keeps identical, and carries out two-year tracking to all patients, to confirm the case where Relapse rate breaks out.Each group is controlled
It is specifically as shown in table 1 to treat situation.Healing described in table refers to that cervical vertebra disease symptoms completely eliminate；Effectively refer in cervical vertebra disease symptoms extremely
A few symptom is improved, but is thoroughly eliminated not yet；Total effective rate refers to cure rate and efficient summation.
Cervical vertebra disease symptoms: nape pain, finger be numb, limbs fatigue, dizziness, Nausea and vomiting.
Table 1 is each group treatment of cervical spondylopathy situation Comparative result
As can be seen from Table 1, test group 1-7 has good therapeutic effect to cervical spondylosis, and cure rate can maintain 50% substantially
More than, total effective rate may remain in 65% or more, especially test group 7, and cure rate can achieve 60%, while total effective rate is protected
It holds 76.7%, therapeutic effect is significant.And the above-mentioned patient being cured is tracked 2 years, only 13 recurrences, radical cure effect is bright
It is aobvious.Compared with test group 1-7, the therapeutic effect of control group 1 and control group 2 is relatively poor, and total effective rate is not higher than 60%, cures
Rate is lower, increases patient's treatment cost to a certain degree.
Embodiment 2:
A kind of Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons is present embodiments provided, which can be straight
It connects and is applied to painful area, be massaged into and fully absorb, daily medication 2-3 times is adhered to can reach therapeutic effect in medication 2-3 weeks.
The present embodiment is equipped with test group and control group, and the specific formula difference of test group and control group is as follows:
In the present embodiment, the formula composition of test group 1-7 is with the test group 1-7 in embodiment 1, and details are not described herein.
In the present embodiment, the Chinese medicine external prescription of test group 1-7 is prepared via a method which:
(1) appropriate folium artemisiae argyi, ramulus cinnamomi, safflower, Radix Angelicae Sinensis, Cortex Eucommiae, herba taxilli, Rhizoma Chuanxiong, rhizoma corydalis are weighed and is respectively crushed into coarse powder, is mixed
Mixed-powder is formed after uniformly, it is spare；
(2) mixed-powder deionized water heating and refluxing extraction obtained by step (1), the weight ratio of deionized water and mixed-powder
It is 10, Extracting temperature is 90 DEG C, and extraction time is 3 times, i.e., the filter residue obtained after extracting for the first time repeats extraction 2 times, for the first time
Extraction time is 2 hours, and second of extraction time is 1.5 hours, and third time extraction time is 1 hour, and 3 extracting solutions are closed
And filter, deionized water is recycled, filtrate is obtained, it is spare；
(3) in step (2) gained filtrate successively after the strainer filtering of 20 mesh, 40 mesh, 100 mesh, 200 mesh and 400 mesh to get
Mix Chinese medicine extract；
(4) suitable menthol and vanillyl butyl ether are sequentially added in the mixing Chinese medicine extract in step (3), stirring is equal
Finished product medicament is obtained after even.
Wherein, the vanillyl butyl ether is obtained by supercritical extraction.
In the present embodiment, the formula composition of control group 1 and control group 2 is identical as control group 1 in embodiment 1 and control group 2,
Details are not described herein.The Chinese medicine external prescription preparation method of control group 1 and control group 2 in the present embodiment is and in the present embodiment
The preparation method of Chinese medicine external prescription described in test group 1-7 is similar, and this will not be repeated here.
270 patient with cervical Spondylopathy are chosen as subjects, are randomly divided into 9 groups, examination is respectively adopted in every group of 30 people, 1-7 group
Chinese medicine external prescription prepared by group 1-7 is tested, 8 groups and 9 groups are respectively adopted control group 1 and the preparation-obtained Chinese medicine of control group 2
Exterior-applied prescription.All patients are carried out with treatment in three weeks by a definite date, daily medication three times, smears the use of Chinese medicine external prescription every time
Amount keeps identical, and carries out two-year tracking to all patients, to confirm the case where Relapse rate breaks out.Each group is controlled
It is as shown in table 2 to treat situation.Healing described in table refers to that cervical vertebra disease symptoms completely eliminate；Effectively refer at least one in cervical vertebra disease symptoms
A symptom is improved, but is thoroughly eliminated not yet；Total effective rate refers to cure rate and efficient summation.
Table 2 is each group treatment of cervical spondylopathy situation Comparative result
As can be seen from Table 2, test group 1-7 has good therapeutic effect to cervical spondylosis, and cure rate can maintain 55% substantially
More than, total effective rate may remain in 75% or more, especially test group 7, and cure rate can achieve 66.7%, and total effective rate can be with
Reach 86.7%, healing efficiency with higher.And the above-mentioned patient being cured is tracked 2 years, only 18 recurrences, radical cure effect
Fruit is obvious.Compared with test group 1-7, the therapeutic effect of control group 1 and control group 2 is relatively poor, and total effective rate is lower than 75%, controls
More rate is lower, increases patient's treatment cost to a certain degree.
Embodiment 3:
A kind of Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons is present embodiments provided, which can be straight
It connects and is applied to painful area, be massaged into and fully absorb, daily medication 2-3 times is adhered to can reach therapeutic effect in medication 2-3 weeks.
The present embodiment is equipped with test group and control group, and the specific formula difference of test group and control group is as follows:
In the present embodiment, the formula composition of test group 1-7 is with the test group 1-7 in embodiment 1, and details are not described herein.
In the present embodiment, the Chinese medicine external prescription of test group 1-7 is prepared via a method which:
(1) appropriate folium artemisiae argyi, ramulus cinnamomi, safflower, Radix Angelicae Sinensis, Cortex Eucommiae, herba taxilli, Rhizoma Chuanxiong, rhizoma corydalis are weighed and is respectively crushed into coarse powder, is mixed
Mixed-powder is formed after uniformly, it is spare；
(2) mixed-powder deionized water heating and refluxing extraction obtained by step (1), the weight ratio of deionized water and mixed-powder
It is 15, Extracting temperature is 100 DEG C, and extraction time is 3 times, i.e., the filter residue obtained after extracting for the first time repeats extraction 2 times, for the first time
Extraction time is 2 hours, and second of extraction time is 1 hour, and third time extraction time is 1 hour, and 3 extracting solutions are merged
Filtering recycles deionized water, obtains filtrate, spare；
(3) in step (2) gained filtrate successively after the strainer filtering of 20 mesh, 40 mesh, 100 mesh, 200 mesh and 400 mesh to get
Mix Chinese medicine extract；
(4) suitable menthol and vanillyl butyl ether are sequentially added in the mixing Chinese medicine extract in step (3), stirring is equal
Finished product medicament is obtained after even.
Wherein, the vanillyl butyl ether is obtained by supercritical extraction.
In the present embodiment, the formula composition of control group 1 and control group 2 is identical as control group 1 in embodiment 1 and control group 2,
Details are not described herein.The Chinese medicine external prescription preparation method of control group 1 and control group 2 in the present embodiment is and in the present embodiment
Chinese medicine external prescription described in test group 1-7 is similar, and this will not be repeated here.
270 patient with cervical Spondylopathy are equally chosen as subjects, are randomly divided into 9 groups, every group of 30 people, 1-7 group is adopted respectively
The Chinese medicine external prescription prepared by test group 1-7,8 groups and 9 groups are respectively adopted control group 1 and control group 2 is preparation-obtained
Chinese medicine external prescription.All patients are carried out with treatment in three weeks by a definite date, daily medication three times, smears Chinese medicine external prescription every time
Dosage keep identical, and two-year tracking is carried out to all patients, the case where to confirm Relapse rate breaking-out.Each group
Treatment condition it is as shown in table 3.Healing described in table refers to that cervical vertebra disease symptoms completely eliminate；Effectively refer in cervical vertebra disease symptoms extremely
A few symptom is improved, but is thoroughly eliminated not yet；Total effective rate refers to cure rate and efficient summation.
Table 3 is each group treatment of cervical spondylopathy situation Comparative result
| Group | Total number of persons | Healing number | Cure rate | Efficiently individual quantity | It is efficient | Total effective rate |
| Test group 1 | 30 | 20 | 66.7% | 6 | 20% | 86.7% |
| Test group 2 | 30 | 18 | 60% | 9 | 30% | 90% |
| Test group 3 | 30 | 20 | 66.7% | 6 | 20% | 86.7% |
| Test group 4 | 30 | 18 | 60% | 7 | 23.3% | 83.3% |
| Test group 5 | 30 | 19 | 63.3% | 8 | 26.7% | 90% |
| Test group 6 | 30 | 20 | 66.7% | 7 | 23.3% | 90% |
| Test group 7 | 30 | 21 | 70% | 7 | 23.3% | 93.3% |
| Control group 1 | 30 | 15 | 50% | 8 | 26.7% | 76.7% |
| Control group 2 | 30 | 18 | 60% | 6 | 20% | 80% |
As can be seen from Table 3, test group 1-7 is good to the therapeutic effect of cervical spondylosis, and cure rate is up to 60% or more, total effective rate
Substantially 83% or more, especially test group 7 be may remain in, cure rate can achieve 70%, and total effective rate is up to 93.3%, cures
Significant effect.The above-mentioned patient being cured is tracked 2 years, only 14 recurrences, radical cure effect is obvious.With test group 1-7 phase
Than the therapeutic effect of control group 1 and control group 2 is although relatively poor, but compared with embodiment 1 and embodiment 2, also has and obviously mention
Height, total effective rate breach 75%.
Comparative example 1, embodiment 2 and embodiment 3, it is found that compared with test group 1-6, with forming for test group 7
The Chinese medicine external prescription being prepared based on formula has relatively apparent therapeutic effect to cervical spondylosis.Especially with test group
Based on 7 compositing formula, by preparation method disclosed in embodiment 3 obtain Chinese medicine external prescription therapeutic effect more preferably,
Cure rate is up to 70%, and total effective rate is up to 93.3%, and curative effect is substantially better than other test groups and control group.Moreover, identical group
Based on formula, the Chinese medicine external prescription that is acquired by preparation method disclosed in embodiment 1, embodiment 2 and embodiment 3
Drug concentration there is also difference, the Chinese medicine external recipe drug concentration obtained in embodiment 1 is minimum, obtains in embodiment 2
Chinese medicine external recipe drug concentration highest, the Chinese medicine external recipe drug moderate concentration obtained in embodiment 3 obtain in embodiment 3
The Chinese medicine external prescription obtained also complies with the dose requirement of monarch, has not only saved cost, but also send out prescription drug effect effectively
It waves, is generally satisfactory in clinical application.Therefore, preparation method disclosed in embodiment 3 is best preparation method, with test
Based on the compositing formula of group 7, the Chinese medicine external prescription therapeutic effect obtained using preparation method disclosed in embodiment 3 is best.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie
In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power
Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims
Variation is included within the present invention.
Embodiments of the present invention above described embodiment only expresses, the description thereof is more specific and detailed, but can not
Therefore limitations on the scope of the patent of the present invention are interpreted as, as long as skill obtained in the form of equivalent substitutions or equivalent transformations
Art scheme should all be fallen within the scope and spirit of the invention.
Claims (9)
1. a kind of Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons, which is characterized in that the Chinese medicine external prescription is main
It is made of the bulk pharmaceutical chemicals that following weight matches: 15-30 parts of folium artemisiae argyi, 12-20 parts of ramulus cinnamomi, 15-30 parts of safflower, 15-30 parts of Radix Angelicae Sinensis, Du
15-30 parts secondary, 9-25 parts of herba taxilli, 9-12 parts of Rhizoma Chuanxiong, 6-12 parts of rhizoma corydalis, 1-5 parts of menthol, 1-3 parts of vanillyl butyl ether.
2. a kind of Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons as described in claim 1, which is characterized in that described
Chinese medicine external prescription is mainly made of the bulk pharmaceutical chemicals that following weight matches: 20-25 parts of folium artemisiae argyi, 15-17 parts of ramulus cinnamomi, safflower 20-25
Part, 20-25 parts of Radix Angelicae Sinensis, 20-25 parts of Cortex Eucommiae, 14-20 parts of herba taxilli, 10-11 parts of Rhizoma Chuanxiong, 8-10 parts of rhizoma corydalis, menthol 2-4
Part, 1.5-2.5 parts of vanillyl butyl ether.
3. a kind of Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons as claimed in claim 2, which is characterized in that described
Chinese medicine external prescription is mainly made of the bulk pharmaceutical chemicals that following weight matches: 22 parts of folium artemisiae argyi, 16 parts of ramulus cinnamomi, 22 parts of safflower, Radix Angelicae Sinensis 22
Part, 22 parts of Cortex Eucommiae, 17 parts of herba taxilli, 10.5 parts of Rhizoma Chuanxiong, 9 parts of rhizoma corydalis, 3 parts of menthol, 2 parts of vanillyl butyl ether.
4. a kind of Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons as described in claim 1, which is characterized in that described
Chinese medicine external prescription is mainly made of the bulk pharmaceutical chemicals that following weight matches: 25 parts of folium artemisiae argyi, 20 parts of ramulus cinnamomi, 25 parts of safflower, Radix Angelicae Sinensis 20
Part, 25 parts of Cortex Eucommiae, 20 parts of herba taxilli, 12 parts of Rhizoma Chuanxiong, 9 parts of rhizoma corydalis, 1.5 parts of menthol, 1 part of vanillyl butyl ether.
5. a kind of preparation of Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons according to any one of claims 1-4
Method, which comprises the steps of:
(1) appropriate folium artemisiae argyi, ramulus cinnamomi, safflower, Radix Angelicae Sinensis, Cortex Eucommiae, herba taxilli, Rhizoma Chuanxiong, rhizoma corydalis are weighed and is respectively crushed into coarse powder, is mixed
Mixed-powder is formed after uniformly, it is spare；
(2) mixed-powder deionized water heating and refluxing extraction obtained by step (1), Extracting temperature are 80-100 DEG C, extraction time
At least 2 times, 1-2 hours each, extracting solution merges filtering, recycles deionized water, obtains filtrate, spare；
(3) gained filtrate obtains mixing Chinese medicine extract after strainer filtering in step (2), spare；
(4) suitable menthol and vanillyl butyl ether are sequentially added in the mixing Chinese medicine extract in step (3), stirring is equal
Finished product medicament is obtained after even.
6. a kind of preparation method of the Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons as claimed in claim 5, feature
It is, filtrate described in step (3) successively passes through the strainer filtering of 20 mesh, 40 mesh, 100 mesh, 200 mesh and 400 mesh.
7. a kind of preparation method of the Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons as claimed in claim 5, feature
It is, vanillyl butyl ether described in step (4) is obtained by supercritical extraction.
8. a kind of preparation method of the Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons as claimed in claim 5, feature
It is, the weight ratio of deionized water described in step (2) and mixed-powder is 10-30.
9. a kind of preparation method of the Chinese medicine external prescription relieved pain with promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons as claimed in claim 8, feature
It is, in step (2), extraction time is 3 times, and extraction time first time is 2 hours, and second of extraction time is 1 hour, third
Secondary extraction time is 1 hour.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113209258A (en) * | 2021-05-11 | 2021-08-06 | 洪东秀 | Painless bonesetting method |
| CN115245529A (en) * | 2021-04-26 | 2022-10-28 | 上海幼官健康管理有限公司 | A kind of skin penetrant and external pain reliever prepared therefrom |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463221A (en) * | 2013-09-27 | 2013-12-25 | 通化斯威药业股份有限公司 | Analgesic liquid for external application capable of promoting blood circulation, removing blood stasis, reducing swelling and alleviating pain and its preparation method |
| CN106074752A (en) * | 2016-08-10 | 2016-11-09 | 侯志飞 | A kind of external medicine composition treating osteopathia |
| CN108452275A (en) * | 2018-03-22 | 2018-08-28 | 珠海市玖鑫化妆品有限公司 | It is a kind of to have effects that the composition, medicament and preparation method of relaxing tendons and activating collaterals |
-
2019
- 2019-01-24 CN CN201910067603.6A patent/CN109700856A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463221A (en) * | 2013-09-27 | 2013-12-25 | 通化斯威药业股份有限公司 | Analgesic liquid for external application capable of promoting blood circulation, removing blood stasis, reducing swelling and alleviating pain and its preparation method |
| CN106074752A (en) * | 2016-08-10 | 2016-11-09 | 侯志飞 | A kind of external medicine composition treating osteopathia |
| CN108452275A (en) * | 2018-03-22 | 2018-08-28 | 珠海市玖鑫化妆品有限公司 | It is a kind of to have effects that the composition, medicament and preparation method of relaxing tendons and activating collaterals |
Non-Patent Citations (1)
| Title |
|---|
| YAO-XIN GAO等: "Fengshi Gutong Capsule Attenuates Osteoarthritis by Inhibiting MAPK,NF-kB, AP-1, and Akt Pathways", 《FRONTIERS IN PHARMACOLOGY》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115245529A (en) * | 2021-04-26 | 2022-10-28 | 上海幼官健康管理有限公司 | A kind of skin penetrant and external pain reliever prepared therefrom |
| CN113209258A (en) * | 2021-05-11 | 2021-08-06 | 洪东秀 | Painless bonesetting method |
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