CN113813308A

CN113813308A - Medicine for treating burn and scald and preparation method thereof

Info

Publication number: CN113813308A
Application number: CN202010567011.3A
Authority: CN
Inventors: 付学义
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-06-19
Filing date: 2020-06-19
Publication date: 2021-12-21

Abstract

The invention relates to the field of traditional Chinese medicine preparations, in particular to a medicine for treating burns and scalds and a preparation method thereof.

Description

Medicine for treating burn and scald and preparation method thereof

Technical Field

Background

Burn and scald generally refers to the heat, including the tissue damage caused by hot liquid (water, soup, oil, etc.), steam, high temperature gas, flame, hot metal liquid or solid (such as molten steel, steel ingot), etc., mainly refers to skin and/or mucous membrane, and serious patients may also injure the subcutaneous or/and submucosal tissues, such as muscle, bone, joint and even viscera. Scald is a tissue injury caused by hot liquid, steam, etc., and is a kind of thermal burn. The larger the burn area, the more serious the injury to the human body. The deeper the burn, the more severe the damage to the local tissue. The existing treatment technology, especially large-area burn, has not ideal treatment effect of common medicines and instruments. The burn and scald treatment is needed to be cured in the first time on the burn and scald site, large-area skin grafting and scar remaining are avoided, and the difficulty in later recovery is overcome. Because the burn and scald result is serious, the field emergency treatment is needed, and the burn and scald preparation with high cure rate is needed in the treatment process. The patents of 'CN 00133639.8 a medicine for treating burns and scalds' and 'CN 103230471A an external medicine for treating burns and scalds and a preparation method thereof' which have been applied by others are found, and the patents are all the medicines for treating burns and scalds of which the ointment category is more, and the medicines need to be applied by professional medical staff in an aseptic environment, so that the use is inconvenient, and the use is inconvenient particularly in an emergency environment.

Disclosure of Invention

Based on the above, the application provides the medicine for treating the burns and scalds and the preparation method thereof, which do not need to be applied and used in a non-contact way, do not depend on medical staff completely, are more convenient to use, can be used under emergency rescue conditions, quickly reduce the pain of the burn and scald staff, and greatly improve the cure rate of the burns and scalds.

The application provides a medicine for treating burns and scalds and a preparation method thereof, and the medicine comprises the following raw materials in parts by weight:

5-15 parts of garden burnet, 5-15 parts of phellodendron, 5-15 parts of sophora flavescens, 5-15 parts of coptis chinensis, 2-10 parts of scutellaria baicalensis, 3-8 parts of lithospermum and 30-100 parts of ethanol.

The preparation method of the medicine prepared from the components comprises the following steps:

firstly, crushing raw materials by adopting an ultra-micro crushing technology, then taking 10000-35000 ml of ethanol and placing the ethanol in a suitable stainless steel container, adding the crushed raw materials under stirring, adding 10000-30000 ml of ethanol after stirring, stirring again to ensure that the solvent submerges the medicine surface, sealing and soaking for 24-96 hours, stirring for 1-5 times in the middle, pouring out liquid, adding 10000-35000 ml of ethanol into residues, soaking once again, squeezing the residues, finally combining the liquid, standing for 12-36 hours, filtering, and subpackaging to obtain a brownish red liquid finished medicine.

Compared with the prior art, the invention has the following characteristics and beneficial effects:

1. the six Chinese herbal medicines in the invention have the additive and synergistic effects of medicinal properties, have the effects of clearing heat and detoxicating, clearing heat and drying dampness, cooling blood, activating blood, relieving pain, activating blood and dissolving stasis and astringing to form scab, and simultaneously, the alcohol and a large amount of tannin, alkaloid, flavonoid glycoside and the like in the medicines form a medicinal scab barrier on the wound surface, thereby achieving the purposes of astringing, activating blood and dissolving stasis, reducing body fluid exudation and protein loss, resisting bacteria, inhibiting bacteria, forming scab, protecting scab and promoting wound healing, and achieving the purpose of treating burns and scalds.

2. The medical nursing agent is used in a spraying mode, does not need to be smeared, is used in a non-contact mode, does not depend on medical care personnel completely, is more convenient to use, can be used under the emergency condition, and can quickly reduce the pain of people who suffer from burns and scalds.

3. The invention has simple preparation, low price of the used medicine, has the efficacies of promoting tissue regeneration, healing sore, relieving swelling and pain, is convenient to use and is suitable for wide popularization and use.

Detailed Description

In order to make the objects, technical solutions and advantages of the present application more apparent, the present application is further described in detail with reference to the following combinations and examples. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application. All other examples, which can be obtained by a person skilled in the art without any inventive step based on the examples in this application, are within the scope of protection of this application.

The usage and dosage are as follows: repeatedly flushing the wound surface with 1% of hydrogen peroxide and 0.9% of normal saline, then disinfecting with iodophor, cleaning up dirt on the wound surface, shearing off the separated and fallen epidermis, shearing off bubble liquid with scissors if bubbles exist, retaining the bubble skin which is not dissociated, then directly spraying the medicament, carrying out spraying once every 2-3 hours, and carrying out spraying once every 3-4 hours after scabbing until the scabbing is healed; the wound surface of the fresh burn and scald does not need to be treated, and the medicament of the invention is directly sprayed until decrustation and healing.

Note that: patients with transient pain and alcohol allergy are forbidden; pregnant women and patients with cardiovascular and cerebrovascular diseases should use with cautions; fishy smell and mutton are prohibited during administration.

The mechanism of the medicine is as follows:

garden burnet root: the sanguisorba root is used as a medicine, has slightly cold property, bitter taste, cold property and bitter acid taste, and is nontoxic; has the effects of cooling blood, stopping bleeding, clearing away heat and toxic materials, nourishing yin, relieving swelling and healing wound.

Flavescent sophora root: the dried root of the plant is bitter in taste and cold in nature, has the effects of clearing heat and drying dampness, killing insects and promoting urination, and is used for eczema, skin itch, mange and leprosy, and matrine and oxymatrine contained in the sophora flavescens have good leukocyte increasing and anti-inflammatory effects.

Coptis chinensis: perennial herb with extremely bitter taste, the effects of clearing heat and drying dampness, purging fire and removing toxicity, is used for treating damp-heat fullness, vomiting and acid regurgitation, dysentery, jaundice, high fever and coma, hyperactivity of heart fire, vexation and insomnia, blood heat hematemesis and epistaxis, conjunctival congestion, toothache, thirst, carbuncle swelling and furuncle; the external treatment of eczema, eczema and purulent ear canals, the treatment amount of the berberine is quite safe, the side effect is little, and no obstacle is seen after long-term administration.

Phellodendron bark: bitter taste and cold nature, has the effects of clearing heat, eliminating dampness, purging fire, removing steam, removing toxic substances and treating sore, and can be used for treating damp-heat dysentery, stranguria with heat, pain with astringency, bone steaming, fatigue heat, pyocutaneous disease, toxic swelling, eczema, and sore, and berberine and phellodendron bark has good antibacterial effect.

Scutellaria baicalensis: it is used as medicine with bitter taste and cold nature, and has the functions of clearing away heat and toxic material, eliminating dampness, purging fire, arresting bleeding, etc. and has clinical antibacterial effect on skullcap root rather than Chinese goldthread.

Lithospermum: the traditional Chinese medicine composition has the effects of clearing heat, cooling blood, promoting blood circulation, removing toxicity, promoting eruption, and has good antibacterial, anti-inflammatory and wound healing effects on naphthoquinone pigment contained in lithospermum in modern pharmacological research; the benzoquinone and phenol contained in radix Arnebiae have good analgesic effect.

In the prescription, the sanguisorba and the lightyellow sophora root are used as monarch drugs, and the properties and tastes of the sanguisorba and the lightyellow sophora root are bitter, sour and slightly cold, so that the sanguisorba and the lightyellow sophora root have the functions of astringing to stop bleeding, astringing to stop pain; the coptis chinensis, the phellodendron amurense and the scutellaria baicalensis are ministerial drugs, the three yellows have the effects of clearing heat and drying dampness and clearing heat and removing toxicity, and meanwhile, the antibacterial property of the three yellows effectively inhibits susceptible bacteria such as gram-negative bacteria, pseudomonas aeruginosa, escherichia coli and the like for burn and has the effects of inhibiting and killing; the lithospermum is an adjuvant drug, has pungent, bitter and mild properties, comprehensively conditions the properties of the coptis chinensis, the phellodendron amurense and the scutellaria baicalensis, has the effects of astringing to stop bleeding, clearing heat and removing toxicity, and has the effect of inhibiting various bacteria such as gram-negative bacteria, staphylococcus aureus, gram-positive bacteria, pseudomonas aeruginosa and the like.

Case analysis:

1) the cause of injury is: 242 cases of tests are carried out, wherein 98 cases of flame burns such as gasoline, alcohol, electric sparks and the like account for 40.49 percent; 129 cases of hot oil, hot water, hot porridge soup and steam scald account for 53.31%. Acid, alkali, lime, asphalt and the like account for 6.2 percent of 15 cases of chemical burns.

2) Area of burn and scald: 242 cases of the medicament of the invention are mainly treated by 1 to 30 percent of medium and small areas; wherein the area is between 21 and 30 percent and 36 cases account for 14.87 percent. 54 cases with the area between 11 percent and 20 percent account for 22.31 percent; the area is less than 10 percent, 152 cases account for 62.8 percent.

3) Depth of scald: among 242, 131 superficial II degree wounds accounted for 54.13%. 102 superficial II degree and deep II degree wounds exist simultaneously, and account for 42.14%. 7 cases of III degree wound surface with less than 1 percent account for 2.89 percent; the III degree wound surface is more than 1 percent of 2 cases, accounting for 0.08 percent.

5) The comment standard is: after the medicament is sprayed, the wound exudate is reduced, the swelling is reduced, and the wound is scabbed effectively; the wound skin can heal automatically, epithelial cells grow completely to eliminate the wound and the wound is self-healed (more than 1 percent of III-degree wound is not self-healed after spraying medicine and needs decrustation, and granulation wound skin grafting does not account for the cure rate); infection of the wound surface is ineffective.

6) The treatment results are as follows: the medicament is used for treating 240 cases of 242 cases of burns and scalds, which are all the burns and scalds with superficial II degree wound surfaces, deep II degree wound surfaces and III degree wound surfaces within less than 1 percent, and the cure rate is 99.17 percent. 2 cases with more than 1 percent of III degree wound surface are cured by adopting the medicament to protect scab, resist infection, and graft skin on the scab granulation wound surface at the later stage.

7) Statistics of burn and scald wound healing time: the superficial II degree wound surface is healed in 6-10 days, the deep II degree wound surface is healed in 12-24 days, and the wound surface with the III degree wound surface is healed in 28-45 days.

The technical features of the above embodiments can be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the above embodiments are not described, but should be considered as the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the scope of the present application. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. The medicine for treating burns and scalds is characterized by comprising the following raw materials in parts by weight: 5-15 parts of garden burnet, 5-15 parts of phellodendron, 5-15 parts of sophora flavescens, 5-15 parts of coptis chinensis, 2-10 parts of scutellaria baicalensis, 3-8 parts of lithospermum and 30-100 parts of ethanol.

2. The preparation method of the medicine for treating burns and scalds according to claim 1, which is characterized by comprising the following steps: firstly, crushing the raw materials by adopting an ultramicro crushing technology, then placing 10000-35000 ml of ethanol into a suitable stainless steel container, adding the crushed raw materials under stirring, adding 10000-30000 ml of ethanol after stirring, stirring again to ensure that the solvent submerges the medicine surface, soaking for 24-96 hours in a sealed manner, stirring for 1-5 times in the middle, pouring out liquid, adding 10000-35000 ml of ethanol into residues, soaking once again, squeezing residues, finally combining the liquid, standing for 12-36 hours, filtering, and subpackaging to obtain the finished medicine.