CN1135910A - Capsule of Bidoukang - Google Patents
Capsule of Bidoukang Download PDFInfo
- Publication number
- CN1135910A CN1135910A CN 96100733 CN96100733A CN1135910A CN 1135910 A CN1135910 A CN 1135910A CN 96100733 CN96100733 CN 96100733 CN 96100733 A CN96100733 A CN 96100733A CN 1135910 A CN1135910 A CN 1135910A
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- grams
- gram
- radix angelicae
- radix
- capsule
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- 239000002775 capsule Substances 0.000 title claims abstract description 16
- 241000628997 Flos Species 0.000 claims description 10
- 239000009636 Huang Qi Substances 0.000 claims description 9
- 201000009890 sinusitis Diseases 0.000 claims description 8
- 230000001154 acute effect Effects 0.000 abstract description 5
- 230000001684 chronic effect Effects 0.000 abstract description 2
- 241000213006 Angelica dahurica Species 0.000 abstract 2
- 241000218378 Magnolia Species 0.000 abstract 1
- 241000207929 Scutellaria Species 0.000 abstract 1
- 229940107666 astragalus root Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 8
- 230000006872 improvement Effects 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 230000001737 promoting effect Effects 0.000 description 7
- 230000000694 effects Effects 0.000 description 5
- 230000035876 healing Effects 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 206010001076 Acute sinusitis Diseases 0.000 description 3
- 206010009137 Chronic sinusitis Diseases 0.000 description 3
- 208000027157 chronic rhinosinusitis Diseases 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 241000721047 Danaus plexippus Species 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 230000017423 tissue regeneration Effects 0.000 description 2
- 206010002653 Anosmia Diseases 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010050515 Hyposmia Diseases 0.000 description 1
- 206010028748 Nasal obstruction Diseases 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- 208000032023 Signs and Symptoms Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 229940059082 douche Drugs 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- -1 go puppet Substances 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 235000019559 hyposmia Nutrition 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 208000010753 nasal discharge Diseases 0.000 description 1
- 230000000242 pagocytic effect Effects 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000009182 swimming Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000008728 vascular permeability Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
A Chinese-medicinal capsule for curing acute, chronic or suppurative nasosinusitis with high cure rate (95.8%) is prepared from Chuan-xiong rhizome, Chinese angelica root, astragalus root, scutellaria root, dahurian angelica root and magnolia flower.
Description
The present invention relates to a kind of oral medicine for the treatment of acute and chronic sinusitis.
Acute and chronic purulent sinusitis, the traditional Chinese medical science is referred to as " nasal sinusitis ", and the sickness rate height is one of nose section commonly encountered diseases, frequently-occurring disease, is to be the cacorhinia of principal character with the turbid nasal discharge.Primary disease is often with headache, nasal obstruction, hyposmia, and is then empty for a long time endlessly dizzy, influences work, study, even can cause severe complication, causes adverse consequences.
At present, the treatment measure to this disease both at home and abroad mainly contains: use antibiosis control infection usually, Chang Buneng eradicates focus; Local puncture douche therapy, dangerous big and easily recurrence; Oral Chinese patent medicine, as " HUODAN WAN " of domestic current, because of its bioavailability is low, effectively poor stability only can be controlled acute stage symptom.Still there is not satisfied therapeutic scheme at present both at home and abroad.
The purpose of this invention is to provide a kind of safe, sinusitis Chinese medicine preparation efficiently.
The object of the present invention is achieved like this: according to the etiology and pathology and the local anatomical features of sinusitis, on the basis of determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, use blood circulation promoting and blood stasis dispelling, sensible detoxifcation rule, combination principle according to tcm prescription " monarch, minister, help, make ", through the screening and optimizing combination, a kind of capsule of Bidoukang of being made up of Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Radix Astragali, Radix Scutellariae, the Radix Angelicae Dahuricae, Flos Magnoliae has been proposed, wherein per 10 gram Radix Angelicae Sinensis are joined Rhizoma Chuanxiong 12-18 gram, Radix Astragali 12-18 gram, Radix Scutellariae 20-30 gram, Radix Angelicae Dahuricae 9-15 gram, Flos Magnoliae 8-11 gram.
Rhizoma Chuanxiong, the hot fragrant row of Radix Angelicae Sinensis loose in the capsule of Bidoukang prescription, and blood-activating and qi-promoting, reducing swelling and alleviating pain are monarch; Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication are minister; Assistant is set upright with Radix Astragali QI invigorating, promoting pus discharge and tissue regeneration strengthening, and the power that helps Rhizoma Chuanxiong, Radix Angelicae Sinensis promoting flow of QI and blood to nourish blood is equipped with on the Radix Angelicae Dahuricae fragrance again and reaches, and dispelling wind and relieving pain helps the effect of Radix Scutellariae dampness, and Flos Magnoliae is apt to clearing the nasal passage, for the key medicine of nasal sinusitis makes for assistant altogether.Receive strengthening vital QI to eliminate pathogenic factors altogether, promoting flow of QI and blood, sensible detoxifcation, the merit of evacuation of pus granulation promoting.This prescription is eliminating evil holds concurrently to set upright, and activating blood circulation is held concurrently with benefiting vital QI and blood, and simultaneously using both cold and hot drugs disappears and mends double making, and dispels and tissue regeneration promoting, and tonify without causing stagnation is so be applicable to the disease of various nasal sinusitis.
This preparation meets the Chinese prescription principle, on the basis of not losing former pharmaceutical properties, through process such as extract, go puppet, concentrate, does not contain any additives and chemical excipient, does not find toxic and side effects through clinical verification, possesses the feature of high-efficiency preparation.Use capsule oral, fall rate by improving platelet and erythrocyte surface electric charge and erythroprecipitin thereof, the microcirculation improvement obstacle reaches blood viscosity lowering and vascular permeability (not swimming out of but do not influence leukocyte); Strengthen the phagocytic activity of macrophage; Improve body immunity, antibacterial and suppress the formation of granulation tissue.In formal experiment, the treatment group healing improvement rate of using this agent reaches 95.8%, is 64.4% and contrast I group (HUODAN WAN group) healing improvement rate, and it only is 52.6% that contrast II organizes (Western medicine group) healing improvement rate, analyze by statistics, curative effect has utmost point notable difference (P＜0.01) between three groups.The healing improvement rate of capsule of Bidoukang treatment acute sinusitis is 93.9%, is 97.4% to the healing improvement rate of chronic sinusitis, analyzes by statistics, and curative effect no significant difference (P＞0.05) therefore all has high curative effect to acute and chronic sinusitis between the two.By the comparison of capsule of Bidoukang group and its decoct group (relative dosage of capsule of Bidoukang prescription is decocted in water for oral dose), it is 21% that the decoct group was cured improvement rate on 7th, and Capsules group improvement rate on the 7th is 72.7%, illustrates that Capsules group extremely obviously is better than the decoct group.It is low that capsule of Bidoukang also has a cost, and clinical being convenient to used the acceptant advantage of patient
Embodiment 1
Rhizoma Chuanxiong 15 grams, Radix Angelicae Sinensis 10 grams, the Radix Astragali 15 grams, Radix Scutellariae 20 grams, the Radix Angelicae Dahuricae 12 grams, Flos Magnoliae 8 grams.
Embodiment 2
Rhizoma Chuanxiong 18 grams, Radix Angelicae Sinensis 10 grams, the Radix Astragali 18 grams, Radix Scutellariae 30 grams, the Radix Angelicae Dahuricae 15 grams, Flos Magnoliae 11 grams, Herba Asari 10 grams, Herba Menthae 35 grams.
Embodiment 3
Rhizoma Chuanxiong 12 grams, Radix Angelicae Sinensis 10 grams, the Radix Astragali 12 grams, Radix Scutellariae 25 grams, the Radix Angelicae Dahuricae 9 grams, Flos Magnoliae 9 grams, Herba Asari 6 grams, Herba Menthae 25 grams.
Embodiment 4
Rhizoma Chuanxiong 15 grams, Radix Angelicae Sinensis 10 grams, the Radix Astragali 15 grams, Radix Scutellariae 20 grams, the Radix Angelicae Dahuricae 12 grams, Flos Magnoliae 8 grams, Herba Asari 8 grams, Herba Menthae 30 grams.
Above medicated powder is broken, sieve with No. 2 sieves, leave and take the Radix Angelicae Dahuricae 3 grams, Flos Magnoliae 2 grams, surplus medicinal decocting method extracts, and concentrates, add and leave and take medicine, drying is pulverized, and sieves with No. 6 sieves, mixes, dry heat sterilization is handled, and incapsulates, and removes the outer bur of capsule, the paraffin polishing, and bottling is stored.
Function with cure mainly: QI invigorating, promoting flow of QI and blood, sensible detoxifcation, treatment acute-chronic purulent sinusitis.
Usage and dosage: every day three times, each 4-6 grain, taking medicine after meal.
Claims (3)
1, a kind of capsule for the treatment of sinusitis is characterized in that being made up of Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Radix Astragali, Radix Scutellariae, the Radix Angelicae Dahuricae, Flos Magnoliae, and wherein per 10 gram Radix Angelicae Sinensis are joined Rhizoma Chuanxiong 12-18 gram, Radix Astragali 12-18 gram, Radix Scutellariae 20-30 gram, Radix Angelicae Dahuricae 9-15 gram, Flos Magnoliae 8-11 gram.
2, capsule according to claim 1 is characterized in that also containing Herba Asari, and content is that per 10 gram Radix Angelicae Sinensis are joined Herba Asari 6-10 gram.
3, capsule according to claim 1 and 2 is characterized in that also containing Herba Menthae, and content is that per 10 gram Radix Angelicae Sinensis are joined Herba Menthae 25-35 gram.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96100733 CN1135910A (en) | 1996-01-30 | 1996-01-30 | Capsule of Bidoukang |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96100733 CN1135910A (en) | 1996-01-30 | 1996-01-30 | Capsule of Bidoukang |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1135910A true CN1135910A (en) | 1996-11-20 |
Family
ID=5116704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 96100733 Pending CN1135910A (en) | 1996-01-30 | 1996-01-30 | Capsule of Bidoukang |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1135910A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101322759B (en) * | 2008-07-07 | 2010-09-08 | 张景峰 | Medicament for treating coryza and preparation thereof |
| CN106333998A (en) * | 2016-10-21 | 2017-01-18 | 济宁沭康生物科技有限公司 | Bacteriostatic nasal-spray honeysuckle fluid |
-
1996
- 1996-01-30 CN CN 96100733 patent/CN1135910A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101322759B (en) * | 2008-07-07 | 2010-09-08 | 张景峰 | Medicament for treating coryza and preparation thereof |
| CN106333998A (en) * | 2016-10-21 | 2017-01-18 | 济宁沭康生物科技有限公司 | Bacteriostatic nasal-spray honeysuckle fluid |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination |