CN111803396A - Cosmetic composition based on retinaldehyde and glycylglycine oleamide and preparation method thereof - Google Patents

Abstract

The invention discloses a cosmetic composition based on retinaldehyde and glycylglycine oleamide and a preparation method thereof. The cosmetic composition comprises: 6-15% of glycerol, 2-5% of butanediol, 0.1-0.5% of xanthan gum, 0.05-0.1% of disodium ethylene diamine tetraacetate, 0.1-0.5% of panthenol, 1-3% of methyl glucose sesquistearate, 1-3% of PEG-100 stearate, 3-6% of polydimethylsiloxane, 4-8% of squalane, 0.1-0.5% of retinal, 1-4% of glycylglycine oleamide, 2-3% of truffle extract, 1-2% of plant leaf extract, 0.1-0.2% of caprylyl glycol and the balance of water. The cosmetic composition has the advantages of long-lasting moisture retention and good absorption, and effective components such as retinene, glycylglycine oleamide, truffle extract and the like are absorbed by skin and act synergistically, so that fine lines and wrinkles can be effectively reduced, rough skin can be smoothed, and skin texture can be improved.

Description

A kind of cosmetic composition based on retinal and bisglycine oleamide and preparation method thereof

technical field

The invention relates to the technical field of cosmetics, in particular to a cosmetic composition based on retinal and bisglycine oleamide and a preparation method thereof.

Background technique

The skin is the largest organ of the human body, healthy skin is smooth and elastic, and it ages with age. Women begin to have wrinkles at the age of 25 to 30, and gradually appear pigmented spots, and then the skin becomes loose, rough, dull, and the wrinkles deepen and increase. Therefore, how to remove wrinkles and delay aging is one of the research focuses of cosmetics. Commercial cosmetics mainly focus on moisturizing, and often do not achieve a good wrinkle-removing effect.

SUMMARY OF THE INVENTION

The object of the present invention is to provide a cosmetic composition based on retinal and glycine peptide oleamide and a preparation method thereof to solve the above-mentioned technical problems.

In order to solve the above-mentioned technical problems, the technical scheme of the present invention is:

In the first aspect, the present invention provides a cosmetic composition based on retinal and glycine peptide oleamide, which, by weight percentage, comprises: 6-15% of glycerin, 2-5% of butanediol, xanthan gum 0.1～0.5%, EDTA disodium 0.05～0.1%, Panthenol 0.1～0.5%, Methyl glucose sesquistearate 1～3%, PEG-100 stearate 1～3% , Polydimethylsiloxane 3~6%, Squalane 4~8%, Retinal 0.1~0.5%, Diglycine oleamide 1~4%, Truffle Extract 2~3%, Plant Leaf extract 1-2%, caprylyl glycol 0.1-0.2%, water balance.

Preferably, the truffle extract is selected from any one or more of the truffle niger extract, the summer truffle extract and the white truffle extract.

Further preferably, the truffle extract is a truffle extract.

Preferably, the plant leaf extract is selected from any one or more of parsley leaf extract, bayberry leaf extract, and grape leaf extract.

Further preferably, the plant leaf extract is composed of cilantro leaf extract and grape leaf extract in a weight ratio of 0.5 to 1:1.

Preferably, the cosmetic composition of retinal and glycine peptide oleamide, by weight percentage, comprises: 12% of glycerin, 3% of butanediol, 0.2% of xanthan gum, ethylenediaminetetraacetic acid Sodium 0.1%, Panthenol 0.2%, Methylglucose sesquistearate 2%, PEG-100 Stearate 2%, Dimethicone 5%, Squalane 6.5%, Retinol Aldehyde 0.3%, glycine oleamide 3%, truffle extract 2.4%, plant leaf extract 1.5%, caprylyl glycol 0.2%, water balance.

In the second aspect, the present invention provides a method for preparing a cosmetic composition based on retinal and glycine peptide oleamide as described in the first aspect, comprising the following steps:

(1) Add methylglucose sesquistearate, PEG-100 stearate, polydimethylsiloxane, and squalane into a stirring pot, heat to 80-85°C, stir and mix evenly, to obtain A component;

(2) adding water, glycerol, butanediol, xanthan gum, disodium EDTA and panthenol into a stirring pot, heating to 80-85°C, stirring and mixing evenly to obtain component B;

(3) Add component B into the vacuum emulsifying pot, then add component A, homogenize at 80-85°C for 10-15min, cool down to 40-50°C, add retinal, glycine peptide oleamide , truffle extract, plant leaf extract, caprylyl glycol, homogenize for 5-10min, and stir evenly.

Compared with the prior art, the present invention has the following effects:

The cosmetic composition provided by the present invention has the advantages of lasting moisturizing and good absorption, and the effective ingredients such as retinal, glycine oleamide, truffle extract and plant leaf extract are absorbed through the skin and act synergistically to improve the skin's micro-organisms. Circulation condition, can regulate the metabolism of epidermis and stratum corneum, can effectively reduce fine lines and wrinkles, smooth rough skin, and improve skin texture.

Description of drawings

FIG. 1 is a bar graph of the skin elasticity change rate provided by the present invention.

Detailed ways

The specific embodiments of the present invention will be further described below with reference to the accompanying drawings. It should be noted here that the descriptions of these embodiments are used to help the understanding of the present invention, but do not constitute a limitation of the present invention. In addition, the technical features involved in the various embodiments of the present invention described below can be combined with each other as long as they do not conflict with each other.

Example 1

The preparation method of the cosmetic composition based on retinal and glycine peptide oleamide provided in this embodiment comprises the following steps:

(1) Prepare the following raw materials by weight percentage: glycerin 12%, butanediol 3%, xanthan gum 0.2%, disodium EDTA 0.1%, panthenol 0.2%, methyl glucose sesquihard Fatty acid ester 2%, PEG-100 stearate 2%, dimethicone 5%, squalane 6.5%, retinal 0.3%, glycine oleamide 3%, black spore block 2.4% of bacterial extract, 1.5% of plant leaf extract, 0.2% of caprylyl glycol, and water balance, wherein, the plant leaf extract is composed of serrata leaf extract and grape leaf extract in a weight ratio of 3:4;

(2) Add methylglucose sesquistearate, PEG-100 stearate, polydimethylsiloxane, and squalane into the stirring pot, heat to 80° C., stir and mix well to obtain A component;

(3) adding water, glycerol, butanediol, xanthan gum, disodium EDTA, panthenol into a stirring pot, heating to 80°C, stirring and mixing to obtain component B;

(4) Add component B into the vacuum emulsification pot, then add component A, homogenize at 80°C for 12 minutes, then cool down to 40°C, add retinal, bisglycine oleamide, and truffles to extract Compound, plant leaf extract, caprylyl glycol, homogenize for 8 min, and stir well.

Example 2

The preparation method of the cosmetic composition based on retinal and glycine peptide oleamide provided in this embodiment comprises the following steps:

(1) Prepare the following raw materials by weight percentage: glycerin 6%, butanediol 5%, xanthan gum 0.5%, disodium EDTA 0.1%, panthenol 0.5%, methyl glucose sesquihard Fatty acid ester 3%, PEG-100 stearate 1%, dimethicone 6%, squalane 8%, retinal 0.5%, glycine oleamide 1%, black spore block 3% of bacterial extract, 1% of plant leaf extract, 0.2% of caprylyl glycol, and water balance, wherein, the plant leaf extract is composed of serrata leaf extract and grape leaf extract in a weight ratio of 1:2;

(2) Add methylglucose sesquistearate, PEG-100 stearate, polydimethylsiloxane and squalane into the stirring pot, heat to 85°C, stir and mix well to obtain A component;

(3) adding water, glycerol, butanediol, xanthan gum, disodium EDTA, panthenol into a stirring pot, heating to 85°C, stirring and mixing to obtain component B;

(4) Add component B into the vacuum emulsifying pot, then add component A, homogenize at 85°C for 10 minutes, then cool down to 50°C, add retinal, bisglycine oleamide, and truffles to extract Compound, plant leaf extract, caprylyl glycol, homogenize for 5min, and stir well.

Example 3

The preparation method of the cosmetic composition based on retinal and glycine peptide oleamide provided in this embodiment comprises the following steps:

(1) Prepare the following raw materials by weight percentage: glycerin 15%, butanediol 2%, xanthan gum 0.1%, disodium EDTA 0.05%, panthenol 0.1%, methyl glucose sesquihard Fatty acid ester 1%, PEG-100 stearate 3%, dimethicone 3%, squalane 4%, retinal 0.1%, glycine oleamide 4%, black spore block 2% of bacterial extract, 2% of plant leaf extract, 0.1% of caprylyl glycol, and water balance, wherein, the plant leaf extract is composed of serrata leaf extract and grape leaf extract in a weight ratio of 1:1;

(2) Add methylglucose sesquistearate, PEG-100 stearate, polydimethylsiloxane and squalane into the stirring pot, heat to 85°C, stir and mix well to obtain A component;

(3) adding water, glycerol, butanediol, xanthan gum, disodium EDTA, panthenol into a stirring pot, heating to 85°C, stirring and mixing to obtain component B;

(4) Add component B into the vacuum emulsifying pot, then add component A, homogenize at 85°C for 15 minutes, then cool down to 50°C, add retinal, glycine oleamide, and truffles to extract extract, plant leaf extract, caprylyl glycol, homogenize for 10 min, and stir well.

Example 4

Prepare the following raw materials by weight percentage: glycerin 12%, butanediol 3%, xanthan gum 0.2%, disodium EDTA 0.1%, panthenol 0.2%, methylglucose sesquistearate 2%, PEG-100 stearate 2%, dimethicone 5%, squalane 6.5%, retinal 0.3%, glycine oleamide 3%, truffle niger extract 2.4%, plant leaf extract 1.5%, caprylyl glycol 0.2%, water balance, wherein, the plant leaf extract is composed of bayberry leaf extract and grape leaf extract in a weight ratio of 3:4, according to Example 1. The preparation method makes the finished product.

Example 5

Prepare the following raw materials by weight percentage: glycerin 12%, butanediol 3%, xanthan gum 0.2%, disodium EDTA 0.1%, panthenol 0.2%, methylglucose sesquistearate 2%, PEG-100 stearate 2%, dimethicone 5%, squalane 6.5%, retinal 0.3%, glycine oleamide 3%, truffle niger extract 2.4%, plant leaf extract 1.5%, caprylyl glycol 0.2%, water balance, wherein, the plant leaf extract is composed of fenugreek leaf extract and mulberry leaf extract in a weight ratio of 3:4, according to Example 1 The preparation method makes the finished product.

Example 6

In order to further illustrate the beneficial effects of the present invention, a preparation method similar to that of Example 1 is adopted, and the difference between this example and Example 1 is only that: this example uses the truffle extract.

Example 7

In order to further illustrate the beneficial effects of the present invention, a preparation method similar to that of Example 1 is adopted, and the difference between this example and Example 1 is only that: this example uses the truffle extract.

Example 8

Prepare the following raw materials by weight percentage: glycerin 6%, butanediol 5%, xanthan gum 0.5%, disodium EDTA 0.1%, panthenol 0.5%, methylglucose sesquistearate 3%, PEG-100 Stearate 1%, Dimethicone 6%, Squalane 8%, Retinal 1%, Diglycine Oleamide 1%, Truffles Nigella Extract 3%, plant leaf extract 1%, caprylyl glycol 0.2%, water balance, wherein, the plant leaf extract is composed of serrata leaf extract and grape leaf extract in a weight ratio of 1:2, according to Example 1 The preparation method makes the finished product.

Example 9

Prepare the following raw materials by weight percentage: glycerin 6%, butanediol 5%, xanthan gum 0.5%, disodium EDTA 0.1%, panthenol 0.5%, methylglucose sesquistearate 3%, PEG-100 stearate 1%, dimethicone 6%, squalane 8%, retinal 0.5%, glycine oleamide 0.1%, truffle niger extract 3%, plant leaf extract 1%, caprylyl glycol 0.2%, water balance, wherein, the plant leaf extract is composed of serrata leaf extract and grape leaf extract in a weight ratio of 1:2, according to Example 1 The preparation method makes the finished product.

Example 10

Prepare the following raw materials by weight percentage: glycerin 6%, butanediol 5%, xanthan gum 0.5%, disodium EDTA 0.1%, panthenol 0.5%, methylglucose sesquistearate 3%, PEG-100 stearate 1%, dimethicone 6%, squalane 8%, retinal 0.5%, glycine oleamide 1%, plant leaf extract 1% , Caprylyl glycol 0.2%, water balance, wherein, the plant leaf extract is composed of parsley leaf extract and grape leaf extract in a weight ratio of 1:2, and the finished product is prepared according to the preparation method of Example 1.

Product performance test:

1, carry out heat resistance test, cold resistance test and centrifugal test to above-mentioned embodiment gained product:

(1) Thermal stability test (48°C, 40 days): no oil-water separation phenomenon, qualified;

(2) Cold resistance stability test (-15℃, 40 days): no oil-water separation phenomenon, qualified;

(3) Centrifugal stability test (4000r/min, 30min): qualified.

2. Select 50 subjects aged 20 to 50 years old, randomly divide them into 10 groups, try the products obtained in Examples 1 to 10 respectively, take 0.03 g of the products obtained in Examples 1 to 10, and apply special tapes to cover them. On the subject's back, the skin reaction on the subject's back was observed at 30 min, 6 hours, 12 hours, 24 hours, and 48 hours after removal, and the results were recorded according to the skin reaction grading standard in "Cosmetic Hygiene Standard" (2007 edition).

The test results showed that no adverse skin reaction occurred in each group of subjects, indicating that the products obtained in Examples 1 to 10 were safe to use.

3. Select 100 subjects aged 25 to 40 years old, and randomly divide the subjects into 10 groups with 10 people in each group. The 10 groups of subjects use the products of Examples 1 to 10 respectively, every morning and evening, Take an appropriate amount of the product and apply it to the face, gently circle until the product is completely absorbed, use a skin tester to test the skin elasticity index before the trial and after 7 days of continuous trial, find the average value of each group, and then further calculate the skin elasticity change rate, The calculation formula is as follows: skin elasticity change rate=(skin elasticity index after trial-skin elasticity index before trial)/skin elasticity index before trial×100%, see FIG. 1 for the results.

The above results show that: the product of Example 1 has the best wrinkle-removing effect. Compared with Examples 8 to 10, Example 1 extracts an appropriate amount of retinal, glycine oleamide, truffle extract and plant leaves. When used in combination, the anti-wrinkle effect is better, and these components have a synergistic effect.

The embodiments of the present invention have been described in detail above with reference to the accompanying drawings, but the present invention is not limited to the described embodiments. For those skilled in the art, without departing from the principle and spirit of the present invention, various changes, modifications, substitutions and alterations can be made to these embodiments, which still fall within the protection scope of the present invention.

Claims (7)

1. A cosmetic composition based on retinal and glycylglycine oleamide, characterized in that it comprises, in percentages by weight: 6-15% of glycerol, 2-5% of butanediol, 0.1-0.5% of xanthan gum, 0.05-0.1% of disodium ethylene diamine tetraacetate, 0.1-0.5% of panthenol, 1-3% of methyl glucose sesquistearate, 1-3% of PEG-100 stearate, 3-6% of polydimethylsiloxane, 4-8% of squalane, 0.1-0.5% of retinal, 1-4% of glycylglycine oleamide, 2-3% of truffle extract, 1-2% of plant leaf extract, 0.1-0.2% of caprylyl glycol and the balance of water.

2. The cosmetic composition based on retinal and glycylglycine oleamide according to claim 1, wherein the truffle extract is selected from any one or more of a truffle nigrospora extract, a truffle charantia extract and a truffle alba extract.

3. The cosmetic composition based on retinal and glycylglycine oleamide according to claim 2, characterized in that the truffle extract is truffle nigrospora extract.

4. The cosmetic composition according to claim 1, wherein the plant leaf extract is selected from any one or more of extracts of rosewood leaves, red bayberry leaves and grape leaves.

5. The cosmetic composition based on retinal and glycylglycine oleamide according to claim 4, wherein the plant leaf extract is composed of a dalbergia wood leaf extract and a grape leaf extract at a weight ratio of 0.5 to 1: 1.

6. The cosmetic composition based on retinal and glycylglycine oleamide according to claim 1, wherein the cosmetic composition based on retinal and glycylglycine oleamide comprises, in weight percent: 12% of glycerin, 3% of butanediol, 0.2% of xanthan gum, 0.1% of disodium ethylene diamine tetraacetate, 0.2% of panthenol, 2% of methylglucose sesquistearate, 2% of PEG-100 stearate, 5% of polydimethylsiloxane, 6.5% of squalane, 0.3% of retinal, 3% of glycylglycine oleamide, 2.4% of truffle extract, 1.5% of plant leaf extract, 0.2% of caprylyl glycol and the balance of water.

7. A process for preparing a cosmetic composition based on retinaldehyde and glycylglycine oleamide according to claim 1, comprising the steps of:

(1) adding methyl glucose sesquistearate, PEG-100 stearate, polydimethylsiloxane and squalane into a stirring pot, heating to 80-85 ℃, and uniformly stirring and mixing to obtain a component A;

(2) adding water, glycerol, butanediol, xanthan gum, disodium ethylene diamine tetraacetate and panthenol into a stirring pot, heating to 80-85 ℃, and uniformly stirring and mixing to obtain a component B;

(3) adding the component B into a vacuum emulsifying pot, adding the component A, homogenizing at 80-85 ℃ for 10-15 min, cooling to 40-50 ℃, adding retinal, glycylglycine oleamide, truffle extract, plant leaf extract and caprylyl glycol, homogenizing for 5-10 min, and stirring uniformly.

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