CN1108160C - Medicine for curing stomatocace and its preparation method - Google Patents
Medicine for curing stomatocace and its preparation method Download PDFInfo
- Publication number
- CN1108160C CN1108160C CN00111161A CN00111161A CN1108160C CN 1108160 C CN1108160 C CN 1108160C CN 00111161 A CN00111161 A CN 00111161A CN 00111161 A CN00111161 A CN 00111161A CN 1108160 C CN1108160 C CN 1108160C
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- medicine
- vermilion
- borax
- oral ulcer
- white cocoon
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- 235000010339 sodium tetraborate Nutrition 0.000 claims abstract description 15
- 239000002994 raw material Substances 0.000 claims abstract description 7
- 208000002399 aphthous stomatitis Diseases 0.000 claims description 22
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- 229910017052 cobalt Inorganic materials 0.000 description 2
- 239000010941 cobalt Substances 0.000 description 2
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 2
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- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention provides medicine for treating dental ulcer and a preparation method thereof. The medicine for treating dental ulcer is prepared from raw materials of the following proportion by weight: 5 to 25 of white cocoon, 5 to 20 of coptis, 5 to 20 of natural indigo, 5 to 15 of dried alum, 5 to 15 of borax and 1 to 5 of vermilion, wherein the coptis, the natural indigo, the dried alum, the borax and the vermilion are respectively processed and crushed into a state that the fineness is 200 meshes; the white cocoon is baked, processed and crushed into a state that the fineness is 200 meshes; the whole fine powder is mixed according to the proportion and is sterilized to prepare the medicine.
Description
The present invention relates to a kind of medicine that is used for the treatment of recurrent aphtha, especially a kind of is the medicine of the treatment recurrent aphtha of primary raw material preparation with Chinese medicine, the invention still further relates to the preparation method of this medicine.
Recurrent aphtha is a kind of clinical modal disease of cari oris mucosa, and men and women, old and young can be taken place, and are in the majority with the young and the middle aged, and crowd's prevalence surpasses 10%.This disease is that a kind of the outbreak repeatedly with periodicity is the oral mucosa limitation ulcer infringement of characteristics, can betide any position of oral mucosa, see with lip, cheek, tongue position more, severe patient can bring disaster to pharyngeal mucosa, and many patients are along with the prolongation of the state of an illness, and the ulcer area increases, number increases, pain increases the weight of, healing stage prolongs, and shortens interval and seriously hinders feed and speak, and influences quality of life.
It is many because of retention of heat in the spleen and stomach, hyperactivity of deficient fire that the pathogenic factor of recurrent aphtha, motherland's medical science are thought, then opinions vary for modern medicine study, still do not have final conclusion so far, therefore, also just do not have specificity active drug and Therapeutic Method.The medicine that uses clinically generally all has certain curative effect now, can alleviate local symptom, promotes ulcer healing, but the cost of medicine is higher, generally needs take effect half an hour, lacks nutritional labeling, ulcer healing is slower, and zest or toxic side effect etc. are arranged, and pharmaceutical technology is also complicated.
One of purpose of the present invention is for the oral ulcer patient provides a kind of cost low, rapid-action, contains nutritional labeling, and ulcer healing is rapid, nonirritant and the medicine that has no side effect.It is simple that two of purpose provides a kind of technology that one of achieves the goal, the process for preparing medicine of easy operating.
One of purpose of the present invention can realize by following measure:
Medicine of the present invention has following component to make: (consumption is a weight portion)
White cocoon 5～25 Rhizoma Coptidis 5～20
Indigo Naturalis 5～20 dried Alumens 5～15
Borax 5～15 Vermilion 1～5
Formula optimization weight (part) ratio range of preparation medicine of the present invention is:
White cocoon 5～15 Rhizoma Coptidis 8～15
Indigo Naturalis 8～15 dried Alumens 6～10
Borax 6～10 Vermilion 1～3
The optimum weight of medicine of the present invention (part) proportioning is:
White cocoon 12 Rhizoma Coptidis 8
Indigo Naturalis 10 dried Alumens 10
Borax 6,5 Vermilion 1,5
The said medicament of the present invention is a said dosage form on any pharmaceutics; Said pharmaceutical formulation is a preferred version with powder or pad pasting.
Above-mentioned each component is made medicine production method of the present invention is:
Get earlier Rhizoma Coptidis, Indigo Naturalis, dried Alumen, Borax, Vermilion respectively processing powder be broken into 200 order fineness; White cocoon roasting is crisp, and processing powder is broken into 200 order fineness; Then above-mentioned whole fine powder components are made medicine of the present invention by described mixed and after sterilizing.
Medicine of the present invention is made the agent special plastic bottle that dusts of can packing into behind the powder, also medicated powder can be made pad pasting with medical excipient.
Sterilization of the present invention is conventional ultraviolet or the sterilization of cobalt Room 60.
The described white cocoon of component of the present invention is that silkworm weaves silk will become pupa the time and makes nest, and described white cocoon can replace with real silk or pure squeeze.
The present invention utilizes the Chinese medicine that has no side effect to provide a kind of cost the low medicine that also can reach the clinical cure purpose rapidly for the oral ulcer patient.The present invention is that raw material is made by white cocoon, Rhizoma Coptidis, Indigo Naturalis, dried Alumen, Borax, Vermilion.The Fang Zhongbai cocoon is monarch, and Rhizoma Coptidis, Indigo Naturalis are minister, and assistant is with dried Alumen, Borax, Vermilion.The main component of white cocoon is low molecular aminoacid, contains fibroin, and its molecular structure is similar to the collagen protein that constitutes skin, can strengthen its elasticity and vigor when contacting with human body skin.Also have and good improve blood capillary, promote blood fortune, promote the metabolic effect of skin surface adipose membrane, protein in the white cocoon and main amino acid content are than Margarita height, it is contained in the fibroin that native protein---leucine can be accelerated the metabolism of cell rapidly, promote wound and ulcer healing, and certain antiinflammatory action is arranged.Serine, threonine also have the effect that activates the Skin Cell function, white cocoon powder resolves into protein, the aminoacid with above-mentioned therapeutical effect in the oral cavity rapidly through enzyme, therefore, white cocoon is a kind of good medicine that is used for the treatment of oral ulcer that not it is found that as yet and utilize.Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication in the side can suppress multiple pathogenic bacteria, and good antiinflammatory, antiulcer effect are arranged, and are called the antibiotic king of Chinese medicine by people.The Indigo Naturalis clearing away heat,cooling blood and removing toxin, ancient doctor's nationality Holy Benevolent Prescriptions carries can control aphtha of the mouth and tongue, and modern study also shows can improve the human body immunity, is used for the treatment of leukemia etc. effectively.To be Alumen dissolve and be fired to dried-up getting through heating dried Alumen, it weakens greatly to Mucocutaneous stimulation after calcining, dried Alumen function dampness, convergence detoxifcation, hemostasis, have antibiotic, removing the necrotic tissue, astriction, ancients are used for the treatment of skin infection in the oral cavities such as aphtha of the mouth and tongue, sore throat, toothache, tonsillitis already.Borax function heat-clearing and toxic substances removing, anticorrosion is that treatment is swollen and ache in the throat, the good medicine of aphtha of the mouth and tongue.The redness of the skin or complexion cinnabar of Vermilion for manually making, tradition thinks that Vermilion is that hydrargyrum processes, so poisonous, modern study proof Vermilion is not absorbed under one's belt, the safety non-toxic so enter the mouth in a small amount, meaning can be controlled and have sore throat Vermilion function dampness, parasite killing and counteracting toxic substances in " first aid side " book.At ulcer surface very strong adhesive force is arranged with clinical practice proof Vermilion after deliberation,, can bring into play therapeutical effect better with Vermilion and the above medicine compatibility of respectively distinguishing the flavor of.Take a broad view of full side, prescription is shown an interesting new approach, and section emulates the advanced, and has both met motherland's medicine and pharmacology theory, meets modern medicine and pharmacology research again.With white cocoon serves as that the main medicine for preparing is used for the treatment of recurrent aphtha and other oral cavity skin infection, whenever control a routine patient, used medicine cost only needs several maos, takes effect at once after the medication, and routine patients up to ten thousand use proof through recent two decades, find no invalid case, medicine of the present invention has the nutritional labeling of abundant promotion wound healing, and general patient's ulcer healing needs 2～3 days, and the phenomenon of recurrence is rarely found, in addition, nonirritant and having no side effect.This medicine also can be widely used in oral cavity skin ulcers such as thrush, angular cheilitis and burst, and once has China to help the non-expert of medical team Africa of taking in addition, is used for the treatment of ulcer due to the AIDS human mouth monilial infection, and is respond well.
Model case:
1, Du XX, man, 49 years old, the cadre of Military Affairs Office suffered from apoplexy before 5 years, hemiplegia still after treatment, slurred speech, oral ulcer will be found in bed from the end of the year 1999 all the year round, see with the tongue buccal more, invalid in certain hospital with western medicines in treatment, after New Year's Day in 2000, ulcer spreads to whole oral cavity, continues outbreak, does not have the obvious cycle, pain unbearably, diet very the difficulty, come to seek medical advice on February 6th, 2000.Make it accompany family members that medicine belt of the present invention is gone home, cancel and dip in this medicated powder again all over being coated with the affected part after malicious cotton swab dips in normal saline, one for several times, and the emphasis ulcer surface is stained with medicated powder with antiseptic gauze and pastes plug, through week treatment, patient's readme: the instant pain in medicine-feeding back obviously alleviates for the first time, and the same day, diet promptly made moderate progress, and the ulcer number obviously reduces after 3 days, ulcer surface dwindles, continue one week of medication, the ulcer recovery from illness is followed up a case by regular visits to and is not had recurrence so far.
2, Xu Shi, woman, 68 years old, the housewife, oral ulcer, outbreak repeatedly, obstinate 3 years was examined on July 26th, 1999, and readme promptly dislikes eating melon and fruit and vegetable from youth, prolonged constipation is whenever busy farming season or dry weather are just got angry aphtha of the mouth and tongue, the external BINGPENG SAN, antibiotic medicine for oral administration, all invalid, obeying one section Chinese medicine of letting out fire can temporarily alleviate, and outbreak recently is serious, lip, tongue, cheek, pharynx diffusivity ulcer, pain unbearably, influence diet and speech, be diagnosed as oral ulcer, use medicated powder of the present invention to spray treatment, one for several times, pain relief is promptly felt in the back further consultation of one week, patient's readme medication just for the first time, and the ulcer number subtracts greatly after three days, ulcer surface obviously dwindles, the diet speech is recovered normally substantially, and one week of medication is not outside the ulcer surface that the indivedual areas of depolarization are big and dark thoroughly heals as yet, all the other all heal, the medication three days that continues obtains recovery from illness, follows up a case by regular visits to so far recurrence.
Embodiment:
Take by weighing raw material (kilogram) by following proportioning:
White cocoon 12 Rhizoma Coptidis 10
Indigo Naturalis 10 dried Alumens 8,5
Borax 8,5 Vermilion 2
Production method is as follows:
A, get Rhizoma Coptidis, Indigo Naturalis, dried Alumen, Borax, Vermilion and process pulverizing respectively, cross 200 mesh sieves, standby;
B, white cocoon roasting is crisp, processing is pulverized, and crosses 200 mesh sieves, and is standby;
C, the fine powder of above-mentioned a, b two-step is inserted the mixing drum mixing;
D, get the agent special plastic bottle that dusts through disinfection by ultraviolet light, fill in Drug Manufacturing Room, every bottle 3 gram is labelled after filling and sealing is good and is put cobalt Room 60 and sterilize, thereby makes powder of the present invention.
Claims (6)
1, a kind of medicine for the treatment of oral ulcer is characterized in that it is the medicament that has the following weight proportion raw material to make
White cocoon 5～25 Rhizoma Coptidis 5～20
Indigo Naturalis 5～20 dried Alumens 5～15
Borax 5～15 Vermilion 1～5
2, the medicine of treatment oral ulcer according to claim 1, wherein the weight proportion of each raw material is
White cocoon 5～15 Rhizoma Coptidis 8～15
Indigo Naturalis 8～15 dried Alumens 6～10
Borax 6～10 Vermilion 1～3
3, the medicine of treatment oral ulcer according to claim 1, wherein the weight proportion of each raw material is
White cocoon 12 Rhizoma Coptidis 8
Indigo Naturalis 10 dried Alumens 10
Borax 6,5 Vermilion 1,5
4,, it is characterized in that said medicament is a said dosage form on any pharmaceutics according to the medicine of claim 1,2 or 3 described treatment oral ulcer.
5, the medicine of treatment oral ulcer according to claim 4 is characterized in that said medicament is powder or pad pasting.
6, the preparation method of the medicine of the described treatment oral ulcer of claim 1, it is characterized in that getting earlier Rhizoma Coptidis, Indigo Naturalis, dried Alumen, Borax, Vermilion respectively processing powder be broken into 200 order fineness; White cocoon roasting is crisp, and processing powder is broken into 200 order fineness; Then above-mentioned whole fine powder components are made medicine of the present invention by described mixed and after sterilizing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00111161A CN1108160C (en) | 2000-06-30 | 2000-06-30 | Medicine for curing stomatocace and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00111161A CN1108160C (en) | 2000-06-30 | 2000-06-30 | Medicine for curing stomatocace and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1281708A CN1281708A (en) | 2001-01-31 |
| CN1108160C true CN1108160C (en) | 2003-05-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN00111161A Expired - Fee Related CN1108160C (en) | 2000-06-30 | 2000-06-30 | Medicine for curing stomatocace and its preparation method |
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| Country | Link |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100386091C (en) * | 2004-04-22 | 2008-05-07 | 王松林 | Medicine for treating canker and preparing method |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213594A (en) * | 2015-11-07 | 2016-01-06 | 杜卫卫 | A kind of medicine composition for the treatment of thrush |
-
2000
- 2000-06-30 CN CN00111161A patent/CN1108160C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100386091C (en) * | 2004-04-22 | 2008-05-07 | 王松林 | Medicine for treating canker and preparing method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1281708A (en) | 2001-01-31 |
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