CN1233398C - Medicine for treating stomatocase - Google Patents
Medicine for treating stomatocase Download PDFInfo
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- CN1233398C CN1233398C CN 200310117417 CN200310117417A CN1233398C CN 1233398 C CN1233398 C CN 1233398C CN 200310117417 CN200310117417 CN 200310117417 CN 200310117417 A CN200310117417 A CN 200310117417A CN 1233398 C CN1233398 C CN 1233398C
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- 208000007117 Oral Ulcer Diseases 0.000 claims abstract description 12
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention discloses a medicament for treating recurrent oral ulcers, which is prepared from the following raw materials according to the percentage by weight: 40 to 60% of alum, 2 to 5% of panax notoginseng, 2 to 5% of pearl, 8 to 12% of elephant hide, 8 to 12% of vietnamese sophora root, 3 to 7% of Chinese gall, 2 to 5% of borneol, 3 to 7% of raw licorice root, 1 to 4% of metronidazole tablets, 0.1 to 2% of furazolidone, 2 to 6% of vitamin B2 tablets and 2 to 6% of prednisone tablets. The medicament for treating recurrent oral ulcers has the characteristics of obvious effect, no oral cavity stimulation and no toxic or side effect. The medicament for treating recurrent oral ulcers can reduce the side effect of hormone, enhance the effect of relieve inflammation and accelerate the healing of ulcers. The present invention has good therapeutic effect on recurrent oral ulcers, tonsillitis, sphagitis, swelling pain of gums, mouth and tongue sores, perleche, glossitis, etc.
Description
Technical field
The present invention relates to a kind of medicament for the treatment of recurrent oral ulceration.
Background technology
Recurrent oral ulceration is ulcer infringement common, the most obstinate, the most multiple in the disease of cari oris mucosa, has the rule of cyclic recurrence, and prevalence occupies the oral mucosal disease first place, is about 10-20%, brings great misery and harm to the patient.
Medicine and therapy to the primary disease treatment is a lot of at present, as vitamin, antibiotic, trace element, biological preparation etc., and methods such as the Chinese medicine and the combination of Chinese and Western medicine, but be symptomatic treatment substantially, can only ease the pain and reduce recurrent number, can not control recurrence, and curative effect is also undesirable; Also useful 17-hydroxy-11-dehydrocorticosterone treatment, as prednisone, cortisone, dexamethasone etc., the first time spent is effective, and life-time service is unfavorable to health.
The purpose of this invention is to provide a kind of instant effect,, short treating period non-stimulated, have no side effect, be difficult for the medicament of the treatment oral ulcer of recurrence the oral cavity.
Summary of the invention
The present invention goes into to think that the main interior of recurrent oral ulceration is because the endocrine function imbalance makes autoimmune function reduction, trace element and vitamin deficiency and microcirculation disturbance, hyperactivity of fire caused by deficiency of YIN, pyretic toxicity are burnt bright, feelings will is unsuccessful and undermine heart spleen, heart-fire and spleen are wet to pent up, blocks mechanism of qi, steams in mouth on outer strongly fragrant or interior folder is damp and hot; Exopathogenic factor often by feed hot dry deep fried foodstuff, stress, work fatigue, do not have enough sleep and bring out that this is sick or increase the weight of the state of an illness, therefore should be, skin ulcer is held back in detoxifcation, antiinflammatory is removed to swell, changed saprophytic machine, depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling, lets out damp and hot clearly is the principles of formulating prescriptions with invigorating the spleen and benefiting QI.
The scheme that the present invention adopts is: a kind of medicament for the treatment of oral ulcer, its prescription is made up of the following raw materials by weight percent material: Alumen 40-60%, Radix Notoginseng 2-5%, Margarita 2-5%, Corium elephatis 8-12%, Radix Sophorae Tonkinensis 8-12%, Galla Chinensis 3-7%, Borneolum Syntheticum 2-5%, Radix Glycyrrhizae 3-7%, Metronidazole Tablet 1-4%, furazolidone sheet 0.1-2%, vitamin B
2Sheet 2-6%, prednisone sheet 2-6%.
The preferred weight proportioning of medicament stock material of the present invention is: Alumen 50%, Radix Notoginseng 3%, Margarita 3%, Corium elephatis 10%, Radix Sophorae Tonkinensis 10%, Galla Chinensis 5%, Borneolum Syntheticum 3%, Radix Glycyrrhizae 5%, Metronidazole Tablet 2%, furazolidone sheet 1%, vitamin B
2Sheet 4%, prednisone sheet 4%.
Above-mentioned materials of weight proportions is made powder.
The present invention prescription is all by the requirement process of preparing Chinese medicine of one one of Pharmacopoeia of the People's Republic of China version in 1997.
Alumen dampness convergence detoxifcation in the prescription; Radix Notoginseng promoting blood circulation and stopping pain, muscle-growing and detumescence; Margarita heat-clearing and toxic substances removing, expelling pus and promoting granulation; The Corium elephatis hemostasia and promoting granulation is held back skin ulcer; Extremely bitter and cold in nature, kind pyretic toxicity, the reducing swelling and alleviating pain separated of Radix Sophorae Tonkinensis flavor, the successive dynasties are with the key medicine that is fire-toxin sore throat skin infection; Galla Chinensis heat-clearing and toxic substances removing, removing dampness are held back the skin ulcer hemostasis; Borneolum Syntheticum heat radiation antiinflammatory, pain relieving granulation promoting; The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription; Metronidazole has specially good effect to various anaerobe, stable performance, and action time is permanent, and osmosis is preferably arranged, and is the choice drug of oral cavity infection; Furazolidone is the antibacterials of nitro heterocyclic, escherichia coli, Enterobacter etc. is had the effect of antibiotic, alleviating pain and promotion ulcer healing; Vitamin B
2The metabolism of involved in sugar, protein and fat, relevant with the normal function of keeping oral mucosa.
Prednisone belongs to adrenal cortex hormones drug, has very strong antiinflammatory action, can suppress the inflammation that multiple reason causes, early stage oozing out can reduce inflammation, edema, telangiectasis, leukocyte infiltration and engulf reaction, thereby improve red, swollen, heat, symptoms such as pain, can relax the vigorous reaction that body causes various noxious stimulus things various endotoxic reactions and mesenchymal tissue, increase adaptability and the resistivity of body to pathology damage, therefore prednisone obtains addition with the pharmacological action of said medicine drug combination and works in coordination with, has heat-clearing and toxic substances removing, anti-inflammation detumescence, exudation, eliminate mucosa swelling, promoting blood circulation and stopping pain, eliminating dampness and astringing sores, the effect of hemostasia and promoting granulation, can reduce capillary permeability, stop inflammatory infiltration, blood vessel dilating, improve the wound surface blood microcirculation, can suppress extraordinary cell immune response, regulate and enhancing body's immunological function, prevent and treat the mucocutaneous erosion that causes because of allergy, ulceration, the energy metabolism in the activated cell and the substance transportation of cell membrane, promote the utilization of damaged tissues to oxygen, promote the formation of fresh granulation tissue, promote angiogenesis, quicken the rapid healing of oral injury mucosal ulcer.
Medicament of the present invention has remarkable affinity to the oral cavity epithelial surface, attached to the ulcer surface; Loose, figuration, be dissolved on the ulcer, infiltrate pathological tissues rapidly; Can adhere to lastingly and form thin film on the oral mucosa, protection wound surface, prolong drug action time effectively; Can directedly bring into play drug action; Its drug effect is direct, local concentration is high, absorption is complete, lasting medicine, can promote rapidly that inflammation is eliminated, ulcer healing, instant effect, non-stimulated to the oral cavity, have no side effect, recurrent oral ulceration, tonsillitis, pharyngolaryngitis, gingival swelling and pain, aphtha of the mouth and tongue, angular cheilitis, glossitis etc. had excellent curative.
The specific embodiment
Embodiment 1:
Xiao * *, the woman, 38 years old, suffered from oral ulcer nearly 10 years, the ulcer that diameter about 2-3 millimeter in many places is arranged in places such as soft palate, gingiva, tongue abdomens, heavy when light during the state of an illness, causalgia is obvious when serious, have a meal and drink water all bitterly, what all dare not be eaten, and outbreak increases the weight of year by year repeatedly, once looses with BINGPENG SAN, acute throat trouble and fails to respond to any medical treatment, through using medicament of the present invention local medicine-feeding once before sleeping every night, symptom obviously alleviated in second day, and local again the medicine-feeding once before the sleep in second day evening is after three days, oral ulcer healing, pain disappear, and follow up a case by regular visits to and do not see recurrence in 1 year.
The present invention treats the medicament of recurrent oral ulceration, and its prescription is made up of the following raw materials by weight percent material: Alumen 50%, Radix Notoginseng 3%, Margarita 3%, Corium elephatis 10%, Radix Sophorae Tonkinensis 10%, Galla Chinensis 5%, Borneolum Syntheticum 3%, Radix Glycyrrhizae 5%, Metronidazole Tablet 2%, furazolidone sheet 1%, vitamin B
2Sheet 4%, prednisone sheet 4%, more than all medicines carry out behind quality control that sterilized powder is broken, the canned product that forms sieves.
Embodiment 2:
Temperature * *, the woman 35 years old, suffered from oral ulcer 6 years, outbreak increases the weight of year by year repeatedly, and is invalid through integrative therapy, comes rash preceding 2 all ulcer to increase the weight of, can't feed, severe pain, sialorrhea, obstruction in a minute, took effect the same day after using medicament of the present invention, five days and heal, follows up a case by regular visits to and do not see recurrence more than a year.
The present invention treats the medicament of recurrent oral ulceration, and its prescription is made up of the following raw materials by weight percent material: Alumen 50%, Radix Notoginseng 3%, Margarita 3%, Corium elephatis 10%, Radix Sophorae Tonkinensis 10%, Galla Chinensis 5%, Borneolum Syntheticum 3%, Radix Glycyrrhizae 5%, Metronidazole Tablet 2%, furazolidone sheet 1%, vitamin B
2Sheet 4%, prednisone sheet 4%, more than all medicines carry out behind quality control that sterilized powder is broken, the canned product that forms sieves.
Embodiment 3:
Husky * *, the man, 21 years old, be subjected to the ulcer puzzlement for many years, almost arranged in morbidity a greater part of time in recent years in every month, used a lot of medicines, curative effect is very little, cures after using medicament of the present invention, follows up a case by regular visits to and does not see recurrence more than a year.
The present invention treats the medicament of recurrent oral ulceration, and its prescription is made up of the following raw materials by weight percent material: Alumen 50%, Radix Notoginseng 3%, Margarita 3%, Corium elephatis 10%, Radix Sophorae Tonkinensis 10%, Galla Chinensis 5%, Borneolum Syntheticum 3%, Radix Glycyrrhizae 5%, Metronidazole Tablet 2%, furazolidone sheet 1%, vitamin B
2Sheet 4%, prednisone sheet 4%, more than all medicines carry out behind quality control that sterilized powder is broken, the canned product that forms sieves.
Claims (2)
1. medicament for the treatment of oral ulcer, it is characterized in that: the weight percent content of each medicine of distinguishing the flavor of is: Alumen 40--65%, Radix Notoginseng 2--5%, Margarita 2--5%, Corium elephatis 8--12%, Radix Sophorae Tonkinensis 8--12%, Galla Chinensis 4--7%, Borneolum Syntheticum 2--5%, Radix Glycyrrhizae 4--7%, Metronidazole Tablet 1--4%, furazolidone sheet 0.5--2%, vitamin B2 sheet 3--6%, prednisone sheet 3--6%.
2. treatment oral ulcer medicament according to claim 1, it is characterized in that: the weight percent content of each medicine of distinguishing the flavor of is: Alumen 50%, Radix Notoginseng 3%, Margarita 3%, Corium elephatis 10%, Radix Sophorae Tonkinensis 10%, Galla Chinensis 5%, Borneolum Syntheticum 3%, Radix Glycyrrhizae 5%, Metronidazole Tablet 2%, furazolidone sheet 1%, vitamin B2 sheet 4%, prednisone sheet 4%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310117417 CN1233398C (en) | 2003-12-15 | 2003-12-15 | Medicine for treating stomatocase |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310117417 CN1233398C (en) | 2003-12-15 | 2003-12-15 | Medicine for treating stomatocase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1546142A CN1546142A (en) | 2004-11-17 |
| CN1233398C true CN1233398C (en) | 2005-12-28 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200310117417 Expired - Fee Related CN1233398C (en) | 2003-12-15 | 2003-12-15 | Medicine for treating stomatocase |
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| Country | Link |
|---|---|
| CN (1) | CN1233398C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101264225B (en) * | 2008-04-26 | 2010-10-20 | 聂兆刚 | Orally-administered decoction for treating ulcer in tongue base |
| CN102078490A (en) * | 2011-01-24 | 2011-06-01 | 王凤龙 | Oral ulcer healing liquor and preparation method thereof |
| CN105477429A (en) * | 2015-12-29 | 2016-04-13 | 张利 | Traditional Chinese medicine for treating oral ulcer and preparation method of traditional Chinese medicine |
-
2003
- 2003-12-15 CN CN 200310117417 patent/CN1233398C/en not_active Expired - Fee Related
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|---|---|
| CN1546142A (en) | 2004-11-17 |
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