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CN1188130C - 夸噻平颗粒 - Google Patents

夸噻平颗粒 Download PDF

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Publication number
CN1188130C
CN1188130C CNB00813166XA CN00813166A CN1188130C CN 1188130 C CN1188130 C CN 1188130C CN B00813166X A CNB00813166X A CN B00813166XA CN 00813166 A CN00813166 A CN 00813166A CN 1188130 C CN1188130 C CN 1188130C
Authority
CN
China
Prior art keywords
preparation
water
granule
binding agent
dibenzo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB00813166XA
Other languages
English (en)
Chinese (zh)
Other versions
CN1374867A (zh
Inventor
D·B·布朗
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10861288&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1188130(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN1374867A publication Critical patent/CN1374867A/zh
Application granted granted Critical
Publication of CN1188130C publication Critical patent/CN1188130C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
CNB00813166XA 1999-09-21 2000-09-18 夸噻平颗粒 Expired - Lifetime CN1188130C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9922271.3A GB9922271D0 (en) 1999-09-21 1999-09-21 Formulation
GB9922271.3 1999-09-21

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNB2004101011599A Division CN1331472C (zh) 1999-09-21 2000-09-18 夸噻平颗粒

Publications (2)

Publication Number Publication Date
CN1374867A CN1374867A (zh) 2002-10-16
CN1188130C true CN1188130C (zh) 2005-02-09

Family

ID=10861288

Family Applications (3)

Application Number Title Priority Date Filing Date
CNB00813166XA Expired - Lifetime CN1188130C (zh) 1999-09-21 2000-09-18 夸噻平颗粒
CNA2006101007643A Pending CN1899288A (zh) 1999-09-21 2000-09-18 夸噻平颗粒
CNB2004101011599A Expired - Lifetime CN1331472C (zh) 1999-09-21 2000-09-18 夸噻平颗粒

Family Applications After (2)

Application Number Title Priority Date Filing Date
CNA2006101007643A Pending CN1899288A (zh) 1999-09-21 2000-09-18 夸噻平颗粒
CNB2004101011599A Expired - Lifetime CN1331472C (zh) 1999-09-21 2000-09-18 夸噻平颗粒

Country Status (37)

Country Link
US (3) US6599897B1 (is)
EP (1) EP1218009B1 (is)
JP (1) JP2003509461A (is)
KR (1) KR100748823B1 (is)
CN (3) CN1188130C (is)
AR (1) AR032596A1 (is)
AT (1) ATE288272T1 (is)
AU (1) AU776292B2 (is)
BG (1) BG65469B1 (is)
BR (1) BR0014107A (is)
CA (1) CA2383131A1 (is)
CO (1) CO5180585A1 (is)
CZ (1) CZ301585B6 (is)
DE (1) DE60017923T2 (is)
DK (1) DK1218009T3 (is)
EE (1) EE200200150A (is)
EG (1) EG24226A (is)
ES (1) ES2235941T3 (is)
GB (2) GB9922271D0 (is)
HK (1) HK1047706B (is)
HU (1) HUP0203531A3 (is)
IL (2) IL148440A0 (is)
IS (1) IS2139B (is)
MX (1) MXPA02002627A (is)
MY (1) MY130208A (is)
NO (1) NO320908B1 (is)
NZ (1) NZ517549A (is)
PL (1) PL198824B1 (is)
PT (1) PT1218009E (is)
RU (1) RU2256453C2 (is)
SI (1) SI1218009T1 (is)
SK (1) SK286884B6 (is)
TR (1) TR200200716T2 (is)
TW (1) TWI226832B (is)
UA (1) UA73529C2 (is)
WO (1) WO2001021179A1 (is)
ZA (1) ZA200201709B (is)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9922271D0 (en) * 1999-09-21 1999-11-17 Zeneca Ltd Formulation
SE0102855D0 (sv) * 2001-08-27 2001-08-27 Astrazeneca Ab Method of treatment
EP1448169A1 (en) * 2001-11-07 2004-08-25 Fujisawa Pharmaceutical Co., Ltd. Method for improving dissolution of poorly dispersible medicaments
JP4514473B2 (ja) * 2004-02-23 2010-07-28 富士通株式会社 コンピュータシステム、中央装置及びプログラム実行方法
UA88792C2 (ru) * 2004-11-10 2009-11-25 Таргасепт, Інк. Гидроксибензоатные соли метаникотиновых соединений
US7459469B2 (en) 2004-11-10 2008-12-02 Targacept, Inc. Hydroxybenzoate salts of metanicotine compounds
EP1879874A2 (en) * 2005-04-21 2008-01-23 Medichem, S.A. Process for preparing quetiapine and quetiapine fumarate
EP1976487A2 (en) 2006-01-25 2008-10-08 Astron Research Limited Sustained release dosage form of phenothiazine derivatives containing channelizer
TWI389889B (zh) * 2006-05-09 2013-03-21 Targacept Inc （２ｓ）-（４ｅ）-ｎ-甲基-５-〔３-（５-異丙氧基吡啶）基〕-４-戊烯-２-胺之新穎多晶型
JP2009536665A (ja) * 2006-05-09 2009-10-15 アストラゼネカ・アクチエボラーグ （２ｓ）−（４ｅ）−ｎ−メチル−５−［３−（５−イソプロポキシピリジン）イル］−４−ペンテン−２−アミンの新規な塩形態
US20090324717A1 (en) * 2006-07-28 2009-12-31 Farmaprojects, S. A. Extended release pharmaceutical formulation of metoprolol and process for its preparation
US20080085888A1 (en) * 2006-09-15 2008-04-10 Breining Scott R Therapeutic Combinations
US8623861B2 (en) * 2006-11-03 2014-01-07 Xin-Min Li Method of treating demyelination diseases
WO2008091592A1 (en) * 2007-01-22 2008-07-31 Targacept, Inc. Intranasal, buccal, and sublingual administration of metanicotine analogs
DE602007009036D1 (de) * 2007-02-14 2010-10-21 Lesvi Laboratorios Sl Pharmazeutische Zusammensetzungen mit Quetiapinfumarat
AU2009219286B2 (en) * 2008-02-27 2012-02-09 Intercontinental Great Brands Llc Multi-region confectionery
DE202009018024U1 (de) 2008-08-01 2010-12-09 Krka Tovarna Zdravil, D.D., Novo Mesto Quetiapin-Zusammensetzung
DE102008046650A1 (de) 2008-09-10 2010-03-11 Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg Quetiapin enthaltende Retardtablette
US20110183963A1 (en) 2009-12-31 2011-07-28 Travis Mickle Amino Acid Conjugates of Quetiapine, Process for Making and Using the Same
LT2544536T (lt) 2010-03-11 2019-02-25 Kempharm, Inc. Kvetiapino riebalų rūgšties konjugatai, jų gamybos būdas ir panaudojimas
WO2011146009A1 (en) 2010-05-20 2011-11-24 Targacept Inc. New process for the preparation of aryl substituted olefinic amines
DE102010033527A1 (de) 2010-08-05 2012-02-09 Acino Pharma Ag Quetiapin-Tabletten
DE102011115690A1 (de) 2011-10-11 2013-04-11 Acino Pharma Ag Quetiapin enthaltende Formulierungen
US9993486B1 (en) 2017-06-19 2018-06-12 Tlc Therapeutics, Llc Oral quetiapine suspension formulations with extended shelf life and enhanced bioavailability
KR20230029605A (ko) * 2020-04-29 2023-03-03 스테판 컴파니 아민, 양성자화 아민 또는 사차 암모늄 화합물을 함유하는 고형 조성물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
GB8705574D0 (en) * 1987-03-10 1987-04-15 Ici Plc Preparation of thiazepine compound
EP0416773B1 (en) * 1989-08-31 1993-03-03 Takeda Chemical Industries, Ltd. Vitamin b12 composition
IT1250701B (it) * 1991-07-24 1995-04-21 Angelini Francesco Ist Ricerca Composizione farmaceutica solida per uso orale a base di dapiprazolo
JPH06100602A (ja) * 1992-09-18 1994-04-12 Asahi Chem Ind Co Ltd 経口固形製剤およびその製造方法
US5397576A (en) * 1992-09-23 1995-03-14 Hoffmann-La Roche Inc. Spray triturated micronutrient compositions
BR9307387A (pt) * 1992-11-09 1999-08-31 Boots Co Plc Agentes terapêuticos
ZA973433B (en) * 1996-04-24 1997-12-10 Shionogi & Co A sertindole-containing preparation and a method for producing the same.
US5948437A (en) 1996-05-23 1999-09-07 Zeneca Limited Pharmaceutical compositions using thiazepine
GB9611328D0 (en) * 1996-05-31 1996-08-07 Zeneca Ltd Pharmaceutical compositions
CN1230883A (zh) * 1996-09-24 1999-10-06 伊莱利利公司 包衣颗粒制剂
US7919119B2 (en) * 1999-05-27 2011-04-05 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
GB9922271D0 (en) * 1999-09-21 1999-11-17 Zeneca Ltd Formulation

Also Published As

Publication number Publication date
EE200200150A (et) 2003-04-15
PT1218009E (pt) 2005-05-31
IL148440A0 (en) 2002-09-12
CZ2002974A3 (cs) 2002-06-12
BR0014107A (pt) 2002-08-20
DK1218009T3 (da) 2005-05-09
GB9922271D0 (en) 1999-11-17
IS2139B (is) 2006-08-15
CO5180585A1 (es) 2002-07-30
US20060159768A1 (en) 2006-07-20
KR100748823B1 (ko) 2007-08-13
GB0021406D0 (en) 2000-10-18
BG65469B1 (bg) 2008-09-30
EP1218009B1 (en) 2005-02-02
NO20021394L (no) 2002-03-20
NZ517549A (en) 2003-10-31
PL198824B1 (pl) 2008-07-31
DE60017923T2 (de) 2006-01-12
ZA200201709B (en) 2003-05-28
EG24226A (en) 2008-11-10
CN1899288A (zh) 2007-01-24
MXPA02002627A (es) 2002-07-30
TR200200716T2 (tr) 2002-06-21
US7022692B2 (en) 2006-04-04
HUP0203531A2 (hu) 2003-02-28
IL148440A (en) 2007-07-04
ES2235941T3 (es) 2005-07-16
SI1218009T1 (en) 2005-06-30
DE60017923D1 (de) 2005-03-10
AU7302300A (en) 2001-04-24
CN1626094A (zh) 2005-06-15
MY130208A (en) 2007-06-29
CA2383131A1 (en) 2001-03-29
CZ301585B6 (cs) 2010-04-21
US6599897B1 (en) 2003-07-29
HK1047706B (en) 2005-06-10
PL357369A1 (en) 2004-07-26
CN1331472C (zh) 2007-08-15
AR032596A1 (es) 2003-11-19
ATE288272T1 (de) 2005-02-15
HK1047706A1 (en) 2003-03-07
IS6308A (is) 2002-03-19
TWI226832B (en) 2005-01-21
CN1374867A (zh) 2002-10-16
BG106509A (en) 2002-12-29
WO2001021179A1 (en) 2001-03-29
SK286884B6 (sk) 2009-07-06
JP2003509461A (ja) 2003-03-11
RU2256453C2 (ru) 2005-07-20
SK3722002A3 (en) 2002-07-02
UA73529C2 (uk) 2005-08-15
NO320908B1 (no) 2006-02-13
HUP0203531A3 (en) 2004-12-28
US20040228914A1 (en) 2004-11-18
AU776292B2 (en) 2004-09-02
EP1218009A1 (en) 2002-07-03
KR20020033186A (ko) 2002-05-04
NO20021394D0 (no) 2002-03-20

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C56 Change in the name or address of the patentee

Owner name: ASTRAZENECA AB

Free format text: FORMER NAME: ASTRA ZENECA AKTIEBOLAG

CP01 Change in the name or title of a patent holder

Address after: Swedish Sodertalje

Patentee after: Astrazeneca (Sweden) AB

Address before: Swedish Sodertalje

Patentee before: Astra Zeneca Aktiebolag

CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20050209