CN115808406A

CN115808406A - Portable urine analyzer

Info

Publication number: CN115808406A
Application number: CN202310000221.8A
Authority: CN
Inventors: 张海悦; 蒋翠翠; 孙景春; 王跃达; 张国光; 陈浩; 李群杰; 徐海金; 李佳林
Original assignee: Jilin Fusheng Medical Device Co ltd
Current assignee: Jilin Fusheng Medical Device Co ltd
Priority date: 2023-01-02
Filing date: 2023-01-02
Publication date: 2023-03-17

Abstract

The invention relates to a portable urine analyzer, which comprises a protective shell, a display screen, a test strip conveying device, a PLC (programmable logic controller) processor, a battery, a scanning head, a dual-wavelength reflectivity detection system and an information management system, wherein the display screen is arranged on the protective shell; the dual-wavelength reflectivity detection system scans the test paper area item by using light with dual wavelengths generated by the light source and the photoelectric conversion mechanism, and determines the content of each biochemical component in urine according to the different reflectivity reflected by the color change generated by the reaction of the urine and the reagent paper; after adopting the structure, the invention has the following advantages: the invention utilizes light of double wavelength generated by the light source and the photoelectric conversion mechanism to scan the test paper area item by item, determines the content of each biochemical component in urine according to the different reflectivity reflected by the color change generated by the reaction of the urine and the reagent paper, is matched with the urine analysis reagent paper for use, and detects and analyzes the biochemical components in a human urine sample.

Description

Portable urine analyzer

Technical Field

The invention relates to the technical field of urine analysis, in particular to a portable urine analyzer.

Background

The urine analyzer is an automatic instrument for measuring certain chemical components in urine, is an important tool for automatically examining urine in a medical laboratory, and has the advantages of simplicity in operation, rapidness and the like. However, the urine analyzer can directly influence the accuracy of the automatic analysis result due to improper use, many intermediate links and influence factors, and can not only cause error of the experimental result, but also delay diagnosis, so that the operator is required to fully know the principle, performance, attention and influence factors of the automatic analyzer, and correctly use the automatic analyzer, so that the result obtained by the urine analyzer is more reliable and accurate.

Urine test is one of three major routine tests of modern clinical medicine, urine analyzer is the special analytical instrument that urine test paper strip that adopts dry chemistry principle to make carries out urine test, this instrument is according to several kinds of specific composition in the urine and test paper piece the colour change that produces and come the testing result, and according to the change through discerning the district colour of reaction reagent, output test report after calculating, urine analyzer divide into large-scale urine analyzer and domestic portable urine analyzer in daily use, in current domestic portable urine analyzer, insert the portable urine analyzer with the test paper strip most alone in, the position of inserting mistake often can appear, lead to the testing result inaccurate, and often can appear staining position inaccurate when staining urine through the test paper, easily make dirty hand, inconvenient use.

Disclosure of Invention

The invention aims to solve the technical problems and provides a portable urine analyzer.

In order to solve the technical problems, the technical scheme provided by the invention is as follows:

a portable urine analyzer comprises a protective shell, a display screen, a test strip conveying device, a PLC (programmable logic controller) processor, a battery, a scanning head, a dual-wavelength reflectivity detection system and an information management system;

the display screen is arranged on the front surface of the protective shell, the PLC processor, the test strip conveying device, the battery, the dual-wavelength reflectivity detection system and the information management system are arranged in the protective shell, and the scanning head is arranged on the outer surface of the protective shell;

the test strip conveying device comprises a driving system and a test strip conveying plate, the driving system can drive the test strip conveying plate to move out or enter the protective shell to reciprocate, and a test strip area is arranged on the test strip conveying plate and can store reagent paper;

the dual-wavelength reflectivity detection system comprises a light source and a photoelectric conversion mechanism, the dual-wavelength reflectivity detection system scans the test paper area item by using light with dual wavelengths generated by the light source and the photoelectric conversion mechanism, and the content of each biochemical component in urine is determined according to the different reflectivity reflected by the color change generated by the reaction of the urine and the reagent paper;

the battery supplies power to the display screen, the test paper strip conveying device, the PLC processor, the scanning head, the light source and the information management system, the test paper strip conveying device is electrically connected with the dual-wavelength reflectivity detection system and the PLC processor, the scanning head is electrically connected with the information management system, and information scanned by the scanning head is stored in the information management system.

Preferably, the wavelength of the dual wavelength light is 525-625nm.

Preferably, the protective shell is provided with a through hole matched with the test strip conveying plate to move.

Preferably, a white reference area is arranged on the test strip transmission plate.

Preferably, the information management system comprises an information storage and a Bluetooth, the information scanned by the scanning head is transmitted to the information storage for storage, and the information of the information storage can be printed by connecting an external printer through the Bluetooth.

Preferably, the driving system may adopt one or more combinations of a screw mechanism, a cylinder mechanism, a worm gear mechanism, a link mechanism, a cam mechanism, a screw mechanism or a rack and pinion mechanism.

Preferably, the interface of the battery is a DCVA charging interface.

After adopting the structure, the invention has the following advantages:

1. the invention utilizes light of double wavelength generated by the light source and the photoelectric conversion mechanism to scan the test paper area item by item, determines the content of each biochemical component in urine according to the different reflectivity reflected by the color change generated by the reaction of the urine and the reagent paper, is matched with the urine analysis reagent paper for use, and detects and analyzes the biochemical components in a human urine sample.

2. The invention uses radio frequency energy to meet specific functions, the radio frequency emission of the invention is very low, and the possibility of generating interference to nearby electronic equipment is very low, and the accuracy is high;

3. the test strip conveying plate disclosed by the invention can be used for generating urine dirt, directly wiping off a little clear water dipped by a cotton swab or cotton cloth, and then wiping off the urine dirt by clear water, so that the test strip conveying plate is convenient to clean and can be used for improving the detection accuracy.

The foregoing summary is provided for the purpose of description only and is not intended to be limiting in any way. In addition to the illustrative aspects, embodiments, and features described above, further aspects, embodiments, and features of the present invention will be readily apparent by reference to the drawings and the following detailed description.

Drawings

In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings used in the embodiments or technical descriptions will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative efforts.

FIG. 1 is a schematic diagram of the present invention.

Fig. 2 is a schematic diagram of the system of the present invention.

FIG. 3 is a schematic view of a test strip delivery device of the present invention.

FIG. 4 is a schematic diagram of a dual wavelength reflectivity detection system of the present invention.

FIG. 5 is a drawing of a split machine interface according to the present invention.

As shown in the figure: 1. a protective housing; 2. a display screen; 3. a PLC processor; 4. a test strip delivery device; 4.1, a driving system; 4.2, a test strip conveying plate; 4.3, a test paper area; 4.4, a white reference area; 5. a battery; 6. a scanning head; 7. a dual wavelength reflectivity detection system; 7.1, a light source; 7.2, a photoelectric conversion mechanism; 8. an information management system; 9. function keys.

Detailed Description

Reference will now be made in detail to the embodiments of the present application, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present application and are not to be construed as limiting the present application.

In the description of the present application, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or may be connected through the use of two elements or the interaction of two elements. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art as appropriate.

The present invention is described in further detail below in conjunction with the full text.

With reference to fig. 1-4, a portable urine analyzer includes a protective housing 1, a display screen 2, a test strip conveyer 4, a PLC processor 3, a battery 5, a scanning head 6, a dual-wavelength reflectivity detection system 7, and an information management system 8;

the display screen 2 is mounted on the front surface of the protective shell 1, the PLC processor 3, the test strip conveying device, the battery 5, the dual-wavelength reflectivity detection system 7 and the information management system 8 are mounted inside the protective shell 1, and the scanning head 6 is mounted on the outer surface of the protective shell 1;

the test strip conveying device 4 comprises a driving system 4.1 and a test strip conveying plate 4.2, the driving system 4.1 can drive the test strip conveying plate 4.2 to move out or enter the protective shell 1 to reciprocate, a test strip area 4.3 is arranged on the test strip conveying plate 4.2, and reagent paper can be stored in the test strip area 4.3;

the dual-wavelength reflectivity detection system 7 comprises a light source 7.1 and a photoelectric conversion mechanism 7.2, the dual-wavelength reflectivity detection system 7 utilizes the light source 7.1 and the photoelectric conversion mechanism 7.2 to generate dual-wavelength light to scan the test paper area 4.3 item by item, and the content of each biochemical component in the urine is determined according to the different reflectivity reflected by the color change generated by the reaction of the urine and the reagent paper;

the battery 5 supplies power to the display screen 2, the test strip conveying device 4, the PLC processor 3, the scanning head 6, the light source 7.1 and the information management system 8, the test strip conveying device 4 is electrically connected with the dual-wavelength reflectivity detection system 7 and the PLC processor 3, the scanning head 6 is electrically connected with the information management system 8, and information scanned by the scanning head 6 is stored in the information management system 8.

The optical wavelength of the dual wavelength is 525-625nm. In the specific implementation of the invention, the detection light wavelength can be selected from 525nm, 565nm, 625nm or 660 nm.

The protective shell 1 is provided with a through hole matched with the test strip conveying plate 4.2 to move. In the specific implementation of the invention, the outer side of the protective shell 1 is provided with the function keys 9, the function keys 9 comprise a key 1, a key 2, a key 3 and a key 4,

and a white reference area 4.4 is arranged on the test strip conveying plate 4.2.

The information management system 8 comprises an information storage and Bluetooth, the information scanned by the scanning head 6 is transmitted to the information storage for storage, and the information of the information storage can be printed by connecting an external printer through the Bluetooth. First, the Addr of the printer is read out to print out the interface information, and the connection address Addr of the printer is recorded. And turns on the bluetooth function. Entering a Bluetooth setting interface of the instrument, filling the read Addr and UUID of the printer into corresponding positions and storing the Addr and UUID, changing the connection type into printer, changing the Bluetooth state into open, and automatically applying related Bluetooth setting by the instrument when exiting the Bluetooth setting interface. If you turn on the bluetooth of the apple device before, please turn it off first. The instrument is successfully connected with the Bluetooth printer, and the external printer can be connected with the instrument through Bluetooth to print

The driving system 4.1 can adopt one or more combinations of a screw rod mechanism, an air cylinder mechanism, a worm and gear mechanism, a link mechanism, a cam mechanism, a screw mechanism or a gear rack mechanism.

And the interface of the battery 5 is a DC5V24A charging interface.

The invention starts up as shown in fig. 5:

sample number: sample number of next sample. Sample number starts from 0001 every day. The sample number can be set by itself, see section of the setting interface, and the instrument assigns a unique number to each sample. The default is to start with number 1 every day, and the next sample is automatically incremented by 1, with the operator modifying the starting sample number before each test. The sample number should not be repeated within one day.

Time and date: current system time and date. Note that the date and time must be determined for correctness prior to sample analysis.

Analyzing the name of the project: the name of 14 items analyzed by the instrument.

Analysis result display area: the analysis result position of each item corresponds to the corresponding analysis item name one by one.

A status bar: the top end of the interface is a status bar, and the status bar appears at the top end of each operation interface. The temperature, the test paper type, the Bluetooth state and the battery state in the display machine are displayed in the status bar.

The temperature in the machine is as follows: when the temperature is too high or too low, the color shows red, and the test cannot be performed. The font is white when the temperature is in the normal range.

The test paper type is as follows: indicating the type of test strip currently selected. 14H represents URS-14FSP test paper.

Bluetooth state: when the Bluetooth is turned off, no Bluetooth state mark exists;

the battery state: the remaining capacity is mainly displayed. Red when the battery is about to run out, and white otherwise.

A prompt bar: and displaying related operation prompts and error information.

A button prompt bar: the displayed buttons correspond to the physical keys below the instrument one to one.

Pressing the "<" key at the sample analysis interface may enter the history interface, as shown in the following figure. Previous test records may be viewed through the "<" and ">" keys. In this interface, the sample number, time and date of the test, the test results (in the following figures, conventional units are used, and other units can be set in the setting interface), and the abnormal results will be displayed in red. If the Bluetooth is in a connected state, such as being connected to a printer, the test result can be printed through an output button; if the Bluetooth is not connected, the button is grey and cannot output.

The menu comprises calibration, bluetooth, setting, bar code, cleaning and maintenance buttons, the selected menu is switched by using < "and >" keys, and a 'confirm' key is pressed to enter a corresponding functional interface. Pressing the "back" key may return to the sample analysis interface.

The dual-wavelength reflectivity detection system 7 of the invention utilizes the light source 7.1 and the photoelectric conversion mechanism 7.2 to generate the light with dual wavelengths to scan the test paper area 4.3 item by item, and determines the content of each biochemical component in urine according to the different reflectivity reflected by the color change generated by the reaction of the urine and the reagent paper as follows:

pH (pH): normal urine is weakly acidic, has a pH value of about 6.0, and has small fluctuation due to influence of diet and active sweating. If the urine is strongly acidic or strongly alkaline, the possibility of acidosis, alkalosis and heat venereal disease should be considered, and further examination should be made for confirmation.

Specific Gravity (SG): the normal specific gravity of urine is generally about 1.015, which changes with age. If the specific gravity is higher, the disease may be caused by high heat dehydration and nephropathy; diabetes insipidus and chronic nephritis should be considered when the specific gravity is low; changes in the specific gravity of urine can also be caused by changes in the renal parenchyma.

Blood (BLD): normal urine BLD should be negative. The increase in BLD may be caused by red blood cells discharged from the kidney or urinary tract hemorrhage, and may be caused by blood circulation disorders.

White blood cells (LEU): normal urine leukocytes should be negative. A positive result indicates the possibility of urine infection.

Nitrite (NIT): the screening index for bacterial infection of urinary system is prepared from nitrate contained in urine of normal human by reducing with bacteria (especially bacteria of Enterobacteriaceae). Therefore, when urinary tract infection (such as cystitis and pyelonephritis) is positive, since enterobacteriaceae (such as Escherichia coli and Proteus) are common bacteria of urinary tract infection, the test is often used as the screening of urinary tract infection.

Protein (PRO): urine protein is an important index for diagnosing, treating and observing kidney diseases after healing. Urinary protein can be discharged and increased under the environment of nephritis, nephropathy, urinary system infection, calculus, malignant tumor, renal tubular acidosis, heavy metal poisoning, renal transplantation and extrusion response sound, and the like, and urinary protein can also be discharged and increased under the environment of hypertensive nephropathy and diabetic nephropathy; therefore, patients with hypertension and diabetes should be examined regularly or quantified for urine protein, and then observed whether kidney is damaged or not. However, the increase of protein may also occur after strenuous activity, cold or fever.

Microalbumin (MA): the microalbumin is mainly used for evaluating kidney diseases, has important significance for monitoring the functions after kidney transplantation and distinguishing glomeruli from tubular diseases, and the level of albumin excretion directly reflects the change degree of glomerular permeability. The development and early diagnosis of the diabetic nephropathy are predicted, and the microalbumin detection is a sensitive index for the occurrence of the diabetic microvascular complication. The excretion rate of microalbumin in urine of hypertension patients is obviously higher than that of normal people, and the increase of microalbumin in urine is an important forecast index of the cardiovascular disease progress.

Ketone body (KET): ketone bodies are produced by oxidation of fatty acids in the liver and are a general term for acetoacetate, β -hydroxybutyrate, and acetone. A positive ketone body in urine is called ketonuria, and is seen in severe diabetes, poisoning, long-term fasting, severe vomiting, diarrhea, dehydration, excessive fat intake and the like.

Glucose (GLU): urine glucose is an index monitored in the process of diabetes diagnosis and treatment, and normal people can generate transient urine glucose increase in a short time, such as when a large amount of glucose liquid is taken, after activities and during pregnancy, so that the clinical significance is avoided. In both primary diabetes, secondary diabetes and renal diabetes, urinary glucose excretion is increased.

Bilirubin (BIL): bilirubin is produced by the degradation of hemoglobin released by the destruction of aged erythrocytes by the treatment of the reticuloendothelial system. Bilirubin is increased in urine in hepatocellular jaundice (such as acute and chronic hepatitis, liver cirrhosis, and liver cancer) and obstructive jaundice (such as cholelithiasis, biliary tract tumor, and pancreatic cancer).

Urobilinogen (PRO): urobilinogen is formed by combining bilirubin, excreting to intestinal tract along with bile and reducing by intestinal bacteria (feces and gallogen). Most of the blood is excreted with the feces, and a small part of the blood is reabsorbed into the colon and excreted by the kidneys. Increased in liver dysfunction, febrile disease, heart failure, hemolytic jaundice, intestinal obstruction, etc.

Creatinine (CRE): urinary creatinine is mainly used for evaluating renal functions, such as acute and chronic renal failure; diagnosis of uremia; evaluation of thyroid function; diagnosis of heart failure, fluid loss, shock, etc.

Calcium ion (Ca): the kit is mainly used for evaluating the functions of thyroid and parathyroid; diagnosis of bone tumors or bone metastases, acute bone atrophy, hypercalcemia or poisoning; diagnosis of vitamin D deficiency; diagnosis of chronic renal insufficiency, malabsorption, osteomalacia, etc.

Ascorbic acid (VC): the high level of ascorbic acid in the long term may be associated with kidney stone formation.

The working principle of the invention is as follows:

the prompt bar of the display of the invention displays "please scan the bar code! ". Please aim the scanning head of the instrument at the bar code on the package of the test paper strip, and the scanning head performs the hair removal; if the prompt bar shows "please put test paper to start testing! "show does not need to scan the bar code, can carry on the test operation directly.

And (3) completely immersing all color blocks of the reagent paper in urine for 2-3S, then taking out, placing the edge of the reagent paper on absorbent paper, and removing redundant urine on the test paper strip. The reagent paper is immediately horizontally placed in a test paper area of an instrument and cannot be skewed, the top end of a reagent paper strip must be aligned with the top end of the test paper area, a dual-wavelength reflectivity detection system of the invention is immediately started, the instrument starts to count down for 1 minute (the test paper reacts for one minute), then the instrument automatically starts to test, firstly, a driving system drives a test paper strip conveying plate to move into a protective shell, meanwhile, the dual-wavelength reflectivity detection system utilizes light of dual wavelengths generated by a light source and a photoelectric conversion mechanism to carry out item-by-item scanning on the test paper area, the content of each biochemical component in urine is determined according to the difference of reflectivity reflected by color change generated by reaction of the urine and the reagent paper, a test structure is conveyed into an information management system, and is connected with an external printer through Bluetooth to print results.

The present invention and its embodiments have been described above, but the description is not limited thereto, and the embodiments shown in the whole text are only one of the embodiments of the present invention, and the actual structure is not limited thereto. In summary, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.

Claims

1. A portable urine analyzer is characterized by comprising a protective shell (1), a display screen (2), a test strip conveying device (4), a PLC (programmable logic controller) processor (3), a battery (5), a scanning head (6), a dual-wavelength reflectivity detection system (7) and an information management system (8);

the display screen (2) is mounted on the front surface of the protective shell (1), the PLC processor (3), the test strip conveying device, the battery (5), the dual-wavelength reflectivity detection system (7) and the information management system (8) are mounted inside the protective shell (1), and the scanning head (6) is mounted on the outer surface of the protective shell (1);

the test strip conveying device (4) comprises a driving system (4.1) and a test strip conveying plate (4.2), the driving system (4.1) can drive the test strip conveying plate (4.2) to move out or enter the protective shell (1) to reciprocate, a test strip area (4.3) is arranged on the test strip conveying plate (4.2), and reagent paper can be stored in the test strip area (4.3);

the dual-wavelength reflectivity detection system (7) comprises a light source (7.1) and a photoelectric conversion mechanism (7.2), the dual-wavelength reflectivity detection system (7) utilizes the light source (7.1) and the photoelectric conversion mechanism (7.2) to generate dual-wavelength light to scan the test paper area (4.3) item by item, and the content of each biochemical component in urine is determined according to the different reflectivity reflected by the color change generated by the reaction of the urine and reagent paper;

display screen (2), test paper strip conveyer (4), PLC treater (3), scanning head (6), light source (7.1) and information management system (8) power supply are given in battery (5), test paper strip conveyer (4) and dual wavelength reflectivity detecting system (7) and PLC treater (3) electricity are connected, scanning head (6) and information management system (8) electricity connect and the information storage of scanning head (6) scanning in information management system (8).

2. The portable urine analyzer according to claim 1, wherein: the optical wavelength of the dual wavelength is 525-625nm.

3. The portable urine analyzer according to claim 1, wherein: the protective shell (1) is provided with a through hole matched with the test strip conveying plate (4.2) to move.

4. The portable urine analyzer according to claim 1, wherein: and a white reference area (4.4) is arranged on the test strip conveying plate (4.2).

5. The portable urine analyzer according to claim 1, wherein: the information management system (8) comprises an information storage and Bluetooth, the information scanned by the scanning head (6) is transmitted to the information storage for storage, and the information of the information storage can be printed by connecting the Bluetooth with an external printer.

6. The portable urine analyzer according to claim 1, wherein: the driving system (4.1) can adopt one or more combinations of a screw rod mechanism, a cylinder mechanism, a worm and gear mechanism, a link mechanism, a cam mechanism, a screw mechanism or a gear rack mechanism.

7. The portable urine analyzer according to claim 1, wherein: and an interface of the battery (5) is a DC5V24A charging interface.