CN117405916A - Sample adding confirmation structure of reagent strip - Google Patents

Abstract

The invention discloses a sample adding confirmation structure of a reagent strip, which comprises a reagent strip component, a reagent bin component, a recognition reading module, a photoelectric sensor component and a transmission mechanism, wherein the reagent bin component comprises a reagent bin and the photoelectric sensor component in the reagent bin, the reagent strip component is inserted into the reagent bin of the reagent bin component, the reagent bin is arranged on the transmission mechanism, the photoelectric sensor component comprises a reflection optocoupler for recognizing the insertion of the reagent strip and a light path recognition module for recognizing sample adding, and the recognition reading module comprises a reagent type recognition module and a fluorescence reading module. Through the sample adding confirmation structure of the reagent strip, the initial time of sample adding is confirmed more accurately, and the sampling is carried out after the set reaction time, so that the reliability of the result is ensured; no additional timing work is required by the tester.

Description

Sample addition confirmation structure of a reagent strip

Technical field

The invention relates to a sample addition confirmation structure, in particular to a sample addition confirmation structure of a reagent strip.

Background technique

The basic principle and clinical application of POCT: infiltrate the relevant liquid reagents in the traditional method into the absorbent materials of filter paper and various microporous membranes to form an integrated dry reagent block, and then fix it on the rigid matrix to form Various forms of diagnostic reagent strips, such as test strips for early pregnancy testing, myoglobin (Mb), CK-MB, troponin I (cTnI) and troponin T (cTnT), biochemical markers for diagnosing AMI, etc. , suitable for whole blood, serum, plasma, urine and other types of samples.

For POCT semi-automatic instruments, the sample adding mode is divided into two modes: internal display panel and external display panel. Usually, after adding the sample, the reaction time is manually counted down, and then the instrument is inserted for result detection.

Existing POCT semi-automatic instruments cannot identify whether to add a sample, and there is a risk that the reaction time cannot be accurately calculated.

Contents of the invention

In order to solve the technical problem that the instrument cannot identify whether to add a sample, the present invention provides a sample addition confirmation structure of a reagent strip.

The present invention provides the following technical solutions:

A reagent strip sample addition confirmation structure includes a reagent strip assembly, a reagent compartment assembly, an identification reading module, a photoelectric sensor assembly and a transmission mechanism. The reagent compartment assembly includes a reagent compartment and a photoelectric sensor assembly in the reagent compartment. The reagent strip The assembly is inserted into the reagent compartment of the reagent compartment assembly. The photoelectric sensor assembly is located below the reagent strip assembly. The photoelectric sensor assembly includes a reflective optical coupler for identifying the insertion of the reagent strip and an optical path identification module for identifying sample addition. The identification reads The module includes a reagent type identification module and a fluorescence reading module. The reagent bin is installed on a transmission mechanism, and the transmission mechanism drives the reagent bin to move away from the reagent strip assembly.

Further, the reagent strip assembly includes a gland, a reagent strip and a bottom case. The reagent strip is placed between the gland and the bottom case. The bottom case is provided with a bottom case limit hole and a bottom case light hole. , there is a light hole on the bottom plate of the reagent strip.

Furthermore, the reagent strip is provided with an NC film area, the gland is provided with a sampling hole, and the gland is also provided with a reagent strip QR code.

Further, the reagent type identification module is used to photograph the QR code of the reagent strip and identify the reagent type, and the fluorescence reading module performs fluorescence measurement on the NC film area of the reagent strip.

Further, the optical path identification module includes an optical path base, an LED, and a photodiode. The photodiode reads the change in reflection value before and after adding the sample through the optical path base.

The reagent bin is installed on a transmission mechanism, and the transmission mechanism drives the reagent bin to move away from the reagent strip assembly.

Further, the transmission mechanism includes a motor, a screw and a connecting block. The motor drives the screw to rotate. The connecting block is installed on the screw, and the connecting block is connected to the reagent chamber.

Further, a limiting structure is provided below the reagent compartment to cooperate with the bottom case limiting hole of the bottom case of the reagent strip assembly.

Compared with the existing technology, the beneficial effects of the present invention are: when the reagent strip assembly is inserted into the reagent compartment, after the reflective optical coupler detects the reagent strip, the reagent type identification module recognizes the reagent type and prompts the user to add a sample. After adding the sample, the optical path recognition module identifies that the reagent strip is added, and the transmission system brings the reagent compartment into the temperature bath inside the machine. The system counts down. After the reaction time is completed, the transmission mechanism drives out with the reagent strip assembly, and the fluorescence reading module proceeds. Fluorescence values. Confirm the structure by adding samples to the reagent strip, so as to more accurately confirm the initial time of adding the sample, and collect the value after the set reaction time to ensure the reliability of the results; no additional timing work is required by the tester.

Description of the drawings

Figure 1 is a schematic structural diagram of the present invention.

Figure 2 is a schematic structural diagram of the reagent strip assembly in the present invention.

Figure 3 is a schematic structural diagram of the photoelectric sensor assembly in the present invention.

Figure 4 is a functional block diagram of the present invention.

In the picture: 1. Reagent strip assembly; 2. Gland, 21. Sample hole, 22. Reagent strip QR code; 3. Reagent strip, 31. Light hole, 32. NC membrane area; 4. Bottom shell, 41. Bottom case limit hole, 42. Bottom case light hole; 5. Identification reading module, 51. Reagent type identification module, 52. Fluorescence reading module; 6. Reagent compartment; 7. Photoelectric sensor assembly, 71. Reflective optical coupler, 72. Optical path seat, 73. LED, 74. Photodiode; 8. Limiting structure; 9. Motor; 10. Connection block; 11. Human-computer interaction system; 12. Lead screw.

Implementation

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts fall within the scope of protection of the present invention.

Please refer to Figures 1-3. The sample addition confirmation structure of a reagent strip according to the present invention includes a reagent strip assembly 1, a reagent compartment assembly, an identification reading module 5, a photoelectric sensor assembly 7 and a transmission mechanism. The reagent compartment assembly includes a reagent compartment. 6 and the photoelectric sensor assembly 7 in the reagent compartment 6. The reagent strip assembly 1 is inserted into the reagent compartment 6 of the reagent compartment assembly. The photoelectric sensor assembly 7 includes a reflective optical coupler 71 for identifying the insertion of the reagent strip and an optical path identification module for identifying the addition of the sample. The reading module 5 includes a reagent type identification module 51 and a fluorescence reading module 52. The reagent bin 6 is installed on a transmission mechanism, and the transmission mechanism can drive the reagent bin 6 to move. Combined with the sample type identified by the reagent type identification module 51, the reaction time countdown begins. After the countdown, the reagent compartment 6 moves away from the reagent strip assembly 1, and the fluorescence reading module 52 collects the fluorescence value of the reagent strip.

The reagent strip assembly 1 includes a gland 2, a reagent strip 3 and a bottom case 4. The reagent strip 3 is placed between the gland 2 and the bottom case 4. The bottom case 4 has a bottom case limit hole 41 and a bottom case light hole. 42. There is a light hole 31 on the bottom plate of the reagent strip 3.

The reagent strip 3 is provided with an NC membrane area 32, the gland 2 is provided with a sampling hole 21, the gland 2 is provided with a reagent strip QR code 22, and the reagent strip assembly 1 is inserted into the reagent compartment 6.

The reagent type identification module 5 is used to photograph the QR code 22 of the reagent strip and identify the reagent type. The fluorescence reading module 52 performs fluorescence sampling on the NC film area 32 of the reagent strip.

The optical path identification module includes an optical path base 72, an LED 73, and a photodiode 74. The optical path identification module is used to identify whether the reagent strip is loaded with a sample.

The reagent bin 6 is installed on a transmission mechanism. The transmission mechanism drives the reagent bin 6 to move. The transmission mechanism includes a motor 9, a screw 12 and a connecting block 10. The motor 9 drives the screw 12 to rotate. The connecting block 10 is installed on the screw 12. The connecting block 10Connect the reagent compartment 6.

The reagent type identification module 51 is used to continuously photograph and identify the reagent strip QR code. The reagent strip QR code can be marked with a laser, and the reagent strip QR code can also be attached to the shell, such as the gland in the reagent strip assembly 1. 2. Set the QR code on the reagent strip.

The fluorescence reading module 52 emits excitation light, such as 365 nm purple light, and receives the excited light from the reagent strip.

The identification reading module 5 and the photoelectric sensor assembly 7 are electrically connected to the human-computer interaction system 11 .

A limiting structure 8 is provided below the reagent chamber 6 to cooperate with the bottom shell limiting hole 41 of the bottom shell 4 of the reagent strip assembly 1 . The photoelectric sensor assembly 7 is located below the reagent strip assembly 1 .

As shown in Figure 4, when the reagent strip assembly 1 is inserted into the reagent compartment 6, the reflective optical coupler 71 detects the reagent strip. Through the photoelectric sensor assembly 7 below the reagent strip assembly 1, the reflective optical coupler 71 is used to determine that the reagent strip assembly has been inserted, and turns on the LED 73 and The photodiode 74 simultaneously uses the reagent type identification module 51 to identify the reagent type of the reagent strip QR code 22, and prompts the user to add the sample to the sampling hole 21 through the human-computer interaction system 11. When the bottom of the reagent strip 3 passes through the light hole After 31 is infiltrated by the sample, the photodiode 74 reads the change in reflection value before and after adding the sample through the optical path base 72, and combined with the sample type identified by the reagent type identification module 51, starts the reaction time countdown. After the countdown ends, the motor 9 passes The connection block 10 drives the reagent chamber 6 to take out the reagent strip assembly 1, and the fluorescence reading module 52 collects the C/T value of the NC film area 32 of the reagent strip 3.

Confirm the structure by adding samples to the reagent strip, so as to more accurately confirm the initial time of adding the sample, and collect the value after the set reaction time to ensure the reliability of the results; no additional timing work is required by the tester.

Although the embodiments of the present invention have been shown and described, those of ordinary skill in the art will understand that various changes, modifications, and substitutions can be made to these embodiments without departing from the principles and spirit of the invention. and modifications, the scope of the invention is defined by the appended claims and their equivalents.

Claims (8)

1. A reagent strip sample addition confirmation structure, characterized by: including a reagent strip assembly (1), a reagent bin assembly, an identification reading module (5), a photoelectric sensor assembly (7) and a transmission mechanism. The reagent bin The assembly includes a reagent compartment (6) and a photoelectric sensor assembly (7) in the reagent compartment (6). The reagent strip assembly (1) is inserted into the reagent compartment (6) of the reagent compartment assembly. The photoelectric sensor assembly (7) is located in the reagent compartment. Below the strip assembly (1), the photoelectric sensor assembly (7) includes a reflective optical coupler (71) for identifying the insertion of the reagent strip and an optical path identification module for identifying sample addition. The identification reading module (5) includes reagent type identification. module (51) and fluorescence reading module (52), the reagent bin (6) is installed on a transmission mechanism, and the transmission mechanism drives the reagent bin (6) to move away from the reagent strip assembly (1). 2. A reagent strip sample addition confirmation structure according to claim 1, characterized in that: the reagent strip assembly (1) includes a gland (2), a reagent strip (3) and a bottom shell (4), The reagent strip (3) is placed between the gland (2) and the bottom case (4). The bottom case (4) is provided with a bottom case limit hole (41) and a bottom case light hole (42). , there is a light hole (31) on the bottom plate of the reagent strip (3). 3. The sample adding confirmation structure of a reagent strip according to claim 2, characterized in that: the reagent strip (3) is provided with an NC film area (32), and the gland (2) is provided with an NC film area (32). There is a sampling hole (21), and a reagent strip QR code (22) is also provided on the gland (2). 4. A reagent strip adding confirmation structure according to claim 3, characterized in that: the reagent type identification module (51) is used to photograph the reagent strip QR code (22) and identify the reagent type, so The fluorescence reading module (52) collects fluorescence values from the NC membrane area (32) of the reagent strip. 5. A reagent strip adding confirmation structure according to claim 1, characterized in that: the optical path identification module includes an optical path base (72), an LED (73), and a photodiode (74). The photodiode (74) reads the change in reflection value before and after adding the sample through the optical path base (72). 6. A reagent strip adding confirmation structure according to claim 1, characterized in that: the reagent bin (6) is installed on a transmission mechanism, and the transmission mechanism drives the reagent bin (6) to move in contact with the reagent strip. Component (1) is detached. 7. A reagent strip adding confirmation structure according to claim 1, characterized in that: the transmission mechanism includes a motor (9), a screw (12) and a connecting block (10), and the motor (9) ) drives the screw (12) to rotate, a connecting block (10) is installed on the screw (12), and the connecting block (10) is connected to the reagent chamber (6). 8. A reagent strip adding confirmation structure according to claim 2, characterized in that: a limiting structure (8) and a bottom shell (4) of the reagent strip assembly (1) are provided below the reagent compartment (6). ) to match the bottom shell limit hole (41).