CN1034261C - 在支架上放置药用胶囊的方法和设备 - Google Patents
在支架上放置药用胶囊的方法和设备 Download PDFInfo
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- CN1034261C CN1034261C CN93108476A CN93108476A CN1034261C CN 1034261 C CN1034261 C CN 1034261C CN 93108476 A CN93108476 A CN 93108476A CN 93108476 A CN93108476 A CN 93108476A CN 1034261 C CN1034261 C CN 1034261C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/14—Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
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Abstract
本发明涉及在一支架上插入一管形药用胶囊的方法和设备。根据本发明，在紧靠在被插入贯通胶囊的开孔的支架前面通过将加压空气吹入该开孔将其扩张。在胶囊进入其位置后，释放压力，从而胶囊开口收缩而胶囊固定在支架上。
Description
本发明涉及一种在支架上放置管状药用胶囊的方法和设备。所涉及的药用胶囊可以是，如一种释放避孕物质的胶囊，而且它在子宫内是安置在用于固定胶囊的适宜支架上。这类避孕工具本身是已知的并以各种不同方法制备。其中，支架是由惰性物质的锚状构件所组成，在其杆上放置有中空管形的药用胶囊。
通过在合适溶剂中膨胀胶囊，然后将膨胀态胶囊插在支架上而使这种管形药用胶囊放置在支架上的方法是已知的。随着溶剂蒸发，胶囊收缩，因而就紧固在支架上。
本发明的目的则是提供一种根据不同的原理的方法和设备。该原理是基于通过内压而扩张胶囊以使之能将支架插入其内部。当压力降低，胶囊就回复到其初态而紧固在支架上。
根据本发明的一个方面，提供一种用于在支架上放置管形药用胶囊，优选地一种包覆的药用胶囊，如避孕胶囊，的方法，其特点在于，在紧靠在被插入贯通胶囊的开孔的支架前边通过加压将该开孔扩张，当支架已推入胶囊中的正确位置，然后通过释放扩张压力而使胶囊紧固在支架上。
根据本发明的另一方面，提供一种实施上述方法将带有一通孔的药用胶囊装在一杆状支架上的设备，如用来将一避孕胶囊装在锚状支架上，其特点在于该设备中包括：
一连结模，它有贯通开孔并相对至少一个通过开孔的平面来说分成两个或多个部件，开孔的长度超过要放置的胶囊的长度；
一个要插入连接模开孔并可在开孔的一端从其中退出的心轴，该心轴的外径相当于要放置的管形胶囊的内径，而其长度相当于要放置的胶囊的长度；
一个可在心轴入口端对面一端插入并退出连接模开孔的压力针，压力针的顶端是开口的，而且其外径相当于要放置的中空胶囊的内径；
由心轴插入的同一端将支架插入连接模开孔以及由此退出支架的装置；
用于控制连接模的部件、心轴、压力针以及支架的插入部件的共同运行的控制装置；以及
用于加压压力针的加压装置。
本发明通过附图予以描述，其中，
图1表明药用胶囊放置的最初阶段时的发明设备。
图2表明放置操作循环的第二阶段。
图3表明在放置阶段中的设备，其药用胶囊是在关闭的连接模中。
图4表明在放置阶段中的设备，其支架是在放置阶段的最初状态。
图5表明在放置最终阶段的设备。
图6表明在放置完成后的设备。
图7表明在制好产品的取出阶段时的设备。
图1表明在放置循环最初阶段时本发明设备的基本部分。连结模或外壳4是在其开启位置，压力针7插入准备接受胶囊1的模的开孔5中，当模开启时，该胶囊在心轴6上送入连接模中。当心轴支持的胶囊与压力针在模开孔端接触时，压力针开始了退回移动。此后，心轴6和其上的胶囊1以及位于对着胶囊端的压力针按一个方向继续移动，使胶囊进入开启的模中。
当胶囊已完全进入连接模，其位置如图3所示，即模被关闭而心轴6开始其返回移动，同时加压针7在胶囊内追随心轴，然后通过由针顶端的开口排出空气而扩大胶囊，因而有助于心轴的移动。在心轴离开胶囊后，压力针到达胶囊的端部，将在其上要放置胶囊的支架3引入胶囊端部此时心轴已从该端部移开，如图4所示。
此后，将支架3推进胶囊以跟随在其前面边退边扩张胶囊的加压针7，如图5和6所示。当支架已推入胶囊中的正确位置，打开连结模而取出制备好的产品。将压力针推到打开的模中，按图1由起点开始操作循环。
所述设备也包括在连接模4两边的两个导杆8、9，它们一方面导引心轴6的移动，另一方面导引压力针7的移动而有助于操作。但如果所述部件的移动和操作的严密性可以用其它方法保证则这些导杆是不必要的。
连接模4的开孔5的截面形状最好选择能与支架3截面的形状相匹配。
为了控制设备各部件正确地共同运转，设备当然包括电控制系统，其详细结构和操作，对本领域技术人员是熟知的，它们不是本发明的主要部分。
Claims (2)
1、一种用于在支架上放置管形药用胶囊，优选地一种包覆的药用胶囊，如避孕胶囊，的方法，其特征在于，在紧靠在被插入贯通胶囊的开孔的支架前边通过加压将该开孔扩张，当支架已推入胶囊中的正确位置，然后通过释放扩张压力而使胶囊紧固在支架上。
2、一种实施权利要求1的方法将带有一通孔的药用胶囊(1)装在一杆状支架(3)上的设备，如用来将一避孕胶囊装在一锚状支架上，其特征在于，该设备中包括：
一连结模(4)，它有贯通开孔(5)并相对至少一个通过开孔的平面来说分成两个或多个部件(4′，4″)，开孔的长度超过要放置的胶囊的长度；
一个要插入连接模开孔(5)并可在开孔的一端从其中退出的心轴(6)，该心轴的外径相当于要放置的管形胶囊的内径，而其长度相当于要放置的胶囊的长度；
一个可在心轴(6)入口端对面一端插入并退出连接模开孔(5)的压力针(7)，压力针的顶端是开口的，而且其外径相当于要放置的中空胶囊的内径；
由心轴(6)插入的同一端将支架(3)插入连接模开孔(5)以及由此退出支架的装置；
用于控制连接模(4)的部件(4′，4″)、心轴(6)、压力针(7)以及支架(3)的插入部件的共同运行的控制装置；以及
用于加压压力针(7)的加压装置。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI923467 | 1992-07-31 | ||
| FI923467A FI90626C (fi) | 1992-07-31 | 1992-07-31 | Menetelmä ja laitteisto lääkeainekapselin asentamiseksi kannattimelle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1081872A CN1081872A (zh) | 1994-02-16 |
| CN1034261C true CN1034261C (zh) | 1997-03-19 |
Family
ID=8535673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93108476A Expired - Lifetime CN1034261C (zh) | 1992-07-31 | 1993-07-26 | 在支架上放置药用胶囊的方法和设备 |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5400804A (zh) |
| EP (1) | EP0652737B1 (zh) |
| JP (1) | JP3258015B2 (zh) |
| KR (2) | KR0142272B1 (zh) |
| CN (1) | CN1034261C (zh) |
| AT (1) | ATE151269T1 (zh) |
| AU (1) | AU670109B2 (zh) |
| BR (1) | BR9306783A (zh) |
| CA (1) | CA2137544C (zh) |
| DE (1) | DE69309689T2 (zh) |
| DK (1) | DK0652737T3 (zh) |
| EE (1) | EE02968B1 (zh) |
| ES (1) | ES2102657T3 (zh) |
| FI (1) | FI90626C (zh) |
| GR (1) | GR3023881T3 (zh) |
| HK (1) | HK130597A (zh) |
| HU (1) | HU217807B (zh) |
| LT (1) | LT3085B (zh) |
| LV (1) | LV10377B (zh) |
| MX (1) | MX9304622A (zh) |
| MY (1) | MY108979A (zh) |
| NO (1) | NO303162B1 (zh) |
| PH (1) | PH30867A (zh) |
| RU (1) | RU2106838C1 (zh) |
| SG (1) | SG83623A1 (zh) |
| TW (1) | TW231266B (zh) |
| UA (1) | UA35595C2 (zh) |
| WO (1) | WO1994003143A1 (zh) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3563370B2 (ja) | 2001-06-08 | 2004-09-08 | Ｎｅｃマイクロシステム株式会社 | 信号生成回路 |
| EP1400258A1 (en) * | 2002-09-18 | 2004-03-24 | Schering Oy | Pharmaceutical composition delivery device and its manufacturing process |
| FR2881046A1 (fr) * | 2005-01-25 | 2006-07-28 | 7 Med Ind Sa | Procede de fabrication d'un reservoir contenant une substance active diffusant a travers le reservoir et installation pour sa mise en oeuvre |
| US7862552B2 (en) * | 2005-05-09 | 2011-01-04 | Boston Scientific Scimed, Inc. | Medical devices for treating urological and uterine conditions |
| JP2007258891A (ja) | 2006-03-22 | 2007-10-04 | Nec Electronics Corp | 相補信号生成回路 |
| ES2338961B2 (es) * | 2007-12-18 | 2011-05-09 | Eurogine S.L. | Maquina bobinadora semiautomatica aplicable para carga de alambre en dius de diferentes tamaños. |
| US8435239B2 (en) | 2009-12-17 | 2013-05-07 | Stryker Trauma Gmbh | Encapsulated screw locking system |
| US8377062B2 (en) | 2009-12-17 | 2013-02-19 | Stryker Trauma Gmbh | Therapeutic agent capsule for implants |
| US10028858B2 (en) | 2011-07-11 | 2018-07-24 | Medicines360 | Intrauterine systems, IUD insertion devices, and related methods and kits therefor |
| TW201350122A (zh) | 2012-04-23 | 2013-12-16 | Bayer Pharma AG | １８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內用途，包含１８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內系統，及其於避孕及婦科治療之用途 |
| BR112014026086A2 (pt) | 2012-04-23 | 2017-07-18 | Bayer Pharma AG | aplicação de 18-metil-15beta,16beta-metilen-19-nor-20-spirox-4-en-3-onas na terapia da menorragia, bem como sistemas intrauterinos contendo 18-metil-15beta,16beta-metilen-19-nor-20-spirox-4-en-3-onas para a terapia de distúrbios de sangramento uterino |
| USD718435S1 (en) | 2012-05-30 | 2014-11-25 | Medicines360 | Intrauterine insertion device |
| WO2015055789A1 (en) | 2013-10-17 | 2015-04-23 | Bayer Pharma Aktiengesellschaft | INTRAVAGINAL USE OF 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, INTRAVAGINAL RINGS COMPRISING 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, AND USE THEREOF IN CONTRACEPTION |
| CN104188745B (zh) * | 2014-09-19 | 2017-01-25 | 卢书美 | 一种妇科取环器 |
| US11096888B2 (en) | 2015-05-13 | 2021-08-24 | Bayer Oy | Long acting drug delivery device and its use in contraception |
| US11278445B2 (en) * | 2015-07-30 | 2022-03-22 | Medicines360 | IUD loading devices and methods for inserting an IUD into an insertion device |
| US11571328B2 (en) | 2018-04-09 | 2023-02-07 | Medicines360 | IUD insertion devices |
| US20200261258A1 (en) | 2019-02-19 | 2020-08-20 | Medicines360 | Devices, systems, methods and kits for insertion and removal of iuds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3323511A (en) * | 1962-03-05 | 1967-06-06 | Holter Company | Radiation source applicator |
| US3509877A (en) * | 1967-08-24 | 1970-05-05 | Leonard S Weiss | Intra-uterine contraceptive device and method of using same |
| US3507274A (en) * | 1968-03-18 | 1970-04-21 | Samuel Soichet | Intra-uterine device |
| EP0082894B1 (en) * | 1981-12-30 | 1986-08-13 | The Population Council, Inc. | Method of making intrauterine devices |
| DE3503354A1 (de) | 1985-02-01 | 1986-08-07 | Ing. Erich Pfeiffer GmbH & Co KG, 7760 Radolfzell | Wirkstoff-spender |
| FI81494C (fi) * | 1987-12-30 | 1990-11-12 | Huhtamaeki Oy | Kasettsystem och anordning foer framstaellning av subkutan preventivkapsel. |
| US4993432A (en) * | 1989-03-28 | 1991-02-19 | Shields Jack W | Applicator for cervical caps |
| US4949732A (en) * | 1989-08-24 | 1990-08-21 | Gyno Pharma Inc. | Apparatus for insertion and fixation of an intra uterine contraceptive device to the uterine fundus |
-
1992
- 1992-07-26 PH PH46575A patent/PH30867A/en unknown
- 1992-07-31 FI FI923467A patent/FI90626C/fi not_active IP Right Cessation
-
1993
- 1993-07-14 EP EP93914768A patent/EP0652737B1/en not_active Expired - Lifetime
- 1993-07-14 WO PCT/FI1993/000296 patent/WO1994003143A1/en not_active Ceased
- 1993-07-14 BR BR9306783A patent/BR9306783A/pt not_active IP Right Cessation
- 1993-07-14 ES ES93914768T patent/ES2102657T3/es not_active Expired - Lifetime
- 1993-07-14 HU HU9403357A patent/HU217807B/hu unknown
- 1993-07-14 UA UA95018092A patent/UA35595C2/uk unknown
- 1993-07-14 AU AU45040/93A patent/AU670109B2/en not_active Expired
- 1993-07-14 JP JP50503694A patent/JP3258015B2/ja not_active Expired - Lifetime
- 1993-07-14 CA CA002137544A patent/CA2137544C/en not_active Expired - Lifetime
- 1993-07-14 DE DE69309689T patent/DE69309689T2/de not_active Expired - Lifetime
- 1993-07-14 RU RU94046420A patent/RU2106838C1/ru active
- 1993-07-14 AT AT93914768T patent/ATE151269T1/de active
- 1993-07-14 TW TW082105620A patent/TW231266B/zh active
- 1993-07-14 DK DK93914768.2T patent/DK0652737T3/da active
- 1993-07-14 SG SG9501081A patent/SG83623A1/en unknown
- 1993-07-14 KR KR1019940704749A patent/KR0142272B1/ko not_active Expired - Lifetime
- 1993-07-20 US US08/093,893 patent/US5400804A/en not_active Expired - Lifetime
- 1993-07-23 LT LTIP811A patent/LT3085B/lt not_active IP Right Cessation
- 1993-07-26 CN CN93108476A patent/CN1034261C/zh not_active Expired - Lifetime
- 1993-07-27 MY MYPI93001466A patent/MY108979A/en unknown
- 1993-07-30 MX MX9304622A patent/MX9304622A/es unknown
- 1993-07-31 LV LVP-93-1003A patent/LV10377B/en unknown
-
1994
- 1994-10-26 EE EE9400177A patent/EE02968B1/xx unknown
- 1994-12-15 NO NO944866A patent/NO303162B1/no not_active IP Right Cessation
- 1994-12-26 KR KR1019940704749A patent/KR950702108A/ko active Granted
-
1997
- 1997-06-26 GR GR970401523T patent/GR3023881T3/el unknown
- 1997-06-26 HK HK130597A patent/HK130597A/en not_active IP Right Cessation
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Expiration termination date: 20130726 Granted publication date: 19970319 |